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The map label for this gene is lon1 [H]

Identifier: 118580698

GI number: 118580698

Start: 2459983

End: 2462022

Strand: Reverse

Name: lon1 [H]

Synonym: Ppro_2283

Alternate gene names: 118580698

Gene position: 2462022-2459983 (Counterclockwise)

Preceding gene: 118580699

Following gene: 118580697

Centisome position: 61.43

GC content: 52.6

Gene sequence:

>2040_bases
ATGGATACCCAATTGAATTGCAGCCTGGACAGCCTCCTGAACCAGCACTTTGCCGGTAAGGTCGTCAGGAAAGACCTGAC
CAAGCTGGTGAAGGAAGGGGCGAACGTTCCAGTCTATGTCCTGGAATACCTTCTGGGGATGTATTGCGCTTCGGATAACG
AAGAGGTCATTCAGGACGGGTTGGTGAACGTCAAGAAGATACTGGCCGAGAACTATGTCCGTCCGGACGAAGCCGAGAAG
GTGAAGTCCAAAATCCGCGAACTGGGAACCTATAAGGTCATCGACAAGGTTACGGTCAAGCTGAATGAAAAACGGGATAC
CTATGAAGCTCTGCTGTCTAACCTGGGGGTGAAGGGGGTTGAGATCGCCAGTGGCACCGTCAAGAAGTACGAAAAGCTGC
TGGTCGGCGGGATCTGGTGCATTGTCACCCTTAATTATTTCTACGAAGAGAATATGAAGGGCTCTCCTTTCAGCATCGGT
GACCTGAAGCCGATTCAGATGCCGAACATGGACATGGAGGGGCTGTTTGAAGGTCGCAAGGCATTCAGCCAGGAACAGTG
GATGGATGTTCTTGTCCGCTCCACCGGCATGGAACCTTCCGTGCTGGAGCAGCGGGTTAAGTGGCACCTGATCGCCAGAA
TGATCCCCTTTGTCGAGAACGGCTATAACCTCTGTGAGCTTGGCCCGAGGGGAACCGGCAAGAGCCATATCTACAAGGAA
ATCAGTCCGAACAGCATCCTTGTTTCCGGCGGACAGACGACCGTAGCCAATCTGTTCTACAACATGGGGTCGCATCAGGT
TGGCCTTGTGGGTATGTGGGATGTGGTCGCCTTCGACGAAGTTGCAGGCATATCCTTCAAGGACAAAGATGGCGTCCAGA
TCATGAAGGACTACATGGCTTCCGGTTCTTTTGCCAGGGGTAAAGATCAGATTTCCGCCAATGCTGCCATGGTCTTCGTC
GGTAACATCAACCAACCGGTGGATACCTTGGTCAAAACCAGCCATCTGCTGGCACCATTCCCCGAGAGCATGATTGATTC
AGCCTTCTTCGACCGCTTCCACTGCTACATCCCCGGCTGGGAAGTTCCGAAGATGCGGCCGGAGTTCTTCACCAACCAGT
ATGGCTTGATTGTAGACTACCTTGCCGAATATCTGCGGGAGATGCGGAAGTACAATTTCTCGGATGCCATCGACAAGTTT
TTCAAGCTGGGGAACAACCTCAACCAGCGGGATACCATCGCCGTTCGCCGAACGGTATCCGGGCTATTGAAGCTCCTGTA
TCCCCATGGTGAATTTGACAAGGAAGCAGTACGCCAATGCCTGCACTATGCCTTGGAGGTCCGCAGGAGGATCAAGGAAC
AGCTCAAGAAAATCGGTGGCATGGAATTTTACGACGTTCATTTCAGCTATATCGACAACGAAAGCATGGAAGAGCGCTTT
ATCGGAGTTCCCGAGCAGGGAGGCAGCTCCCTCATCCCTGAAGGACAGCTGAAACCGGGTACGTTGCACACCGTATCAAC
CGGATCTGGCGGCATGCTTGGCCTATATCGCCTTGAATTGCAGGTCATCGGCGGCAATGGGAAGTTGTCCCTGTCGGGGT
TCGGCACATCCCAAAATGCGAAAGAGCCGGTCAAGGTGGCATTCGACTATTTCAAAGCCAATCTGACCAGGGTAAGCGGA
ATCGCCAAGGCGATTGACCATGATTACCACATGCACATGGTTGAGCTGCATAATACCGGACCTGCATCGGCTTTGACCAT
AGCCTCGTTTGTCTGTTTCTGTTCGGGGTTACTGGGCAAGCCGATACAAAGCCAAATGGTAATTCTGGGTGACATGAGCC
TTGGGGGGAGCATTATTCCGGCGGAGAACCTGGCCGAATCGCTCCAGGTTGCTTTTGATGCAGGAGCAAAAAGGATTCTG
ATTCCCATGAGCAGTGTCAAAGACATACCGACGATACCGGGGGAGTTGTTCGCCAAGTTCCAGACCAGTTTTTATGCTGA
TCCGGTGGATGCGGTATTTAAGGCGCTGGGGGTGGATTAG

Upstream 100 bases:

>100_bases
CTGGTGCTCCGTGATGCAGCGGACAAGACCGAAATCGAGCGGATTCCGCTGACGATTGATTTATCATTTGGAAATGAATT
CTGACCATCAAGGAACCGGT

Downstream 100 bases:

>100_bases
GACCATATGCATGAATACAAGAAAATCCGTTTCTCACTTAAGTCCCTTGCAAAGACGGGCTTAGCTTCAGAAGAAATCAG
AAGCAAGTATTTCGGACATT

Product: ATP-dependent Lon-type protease

Products: NA

Alternate protein names: ATP-dependent protease La 1 [H]

Number of amino acids: Translated: 679; Mature: 679

Protein sequence:

>679_residues
MDTQLNCSLDSLLNQHFAGKVVRKDLTKLVKEGANVPVYVLEYLLGMYCASDNEEVIQDGLVNVKKILAENYVRPDEAEK
VKSKIRELGTYKVIDKVTVKLNEKRDTYEALLSNLGVKGVEIASGTVKKYEKLLVGGIWCIVTLNYFYEENMKGSPFSIG
DLKPIQMPNMDMEGLFEGRKAFSQEQWMDVLVRSTGMEPSVLEQRVKWHLIARMIPFVENGYNLCELGPRGTGKSHIYKE
ISPNSILVSGGQTTVANLFYNMGSHQVGLVGMWDVVAFDEVAGISFKDKDGVQIMKDYMASGSFARGKDQISANAAMVFV
GNINQPVDTLVKTSHLLAPFPESMIDSAFFDRFHCYIPGWEVPKMRPEFFTNQYGLIVDYLAEYLREMRKYNFSDAIDKF
FKLGNNLNQRDTIAVRRTVSGLLKLLYPHGEFDKEAVRQCLHYALEVRRRIKEQLKKIGGMEFYDVHFSYIDNESMEERF
IGVPEQGGSSLIPEGQLKPGTLHTVSTGSGGMLGLYRLELQVIGGNGKLSLSGFGTSQNAKEPVKVAFDYFKANLTRVSG
IAKAIDHDYHMHMVELHNTGPASALTIASFVCFCSGLLGKPIQSQMVILGDMSLGGSIIPAENLAESLQVAFDAGAKRIL
IPMSSVKDIPTIPGELFAKFQTSFYADPVDAVFKALGVD

Sequences:

>Translated_679_residues
MDTQLNCSLDSLLNQHFAGKVVRKDLTKLVKEGANVPVYVLEYLLGMYCASDNEEVIQDGLVNVKKILAENYVRPDEAEK
VKSKIRELGTYKVIDKVTVKLNEKRDTYEALLSNLGVKGVEIASGTVKKYEKLLVGGIWCIVTLNYFYEENMKGSPFSIG
DLKPIQMPNMDMEGLFEGRKAFSQEQWMDVLVRSTGMEPSVLEQRVKWHLIARMIPFVENGYNLCELGPRGTGKSHIYKE
ISPNSILVSGGQTTVANLFYNMGSHQVGLVGMWDVVAFDEVAGISFKDKDGVQIMKDYMASGSFARGKDQISANAAMVFV
GNINQPVDTLVKTSHLLAPFPESMIDSAFFDRFHCYIPGWEVPKMRPEFFTNQYGLIVDYLAEYLREMRKYNFSDAIDKF
FKLGNNLNQRDTIAVRRTVSGLLKLLYPHGEFDKEAVRQCLHYALEVRRRIKEQLKKIGGMEFYDVHFSYIDNESMEERF
IGVPEQGGSSLIPEGQLKPGTLHTVSTGSGGMLGLYRLELQVIGGNGKLSLSGFGTSQNAKEPVKVAFDYFKANLTRVSG
IAKAIDHDYHMHMVELHNTGPASALTIASFVCFCSGLLGKPIQSQMVILGDMSLGGSIIPAENLAESLQVAFDAGAKRIL
IPMSSVKDIPTIPGELFAKFQTSFYADPVDAVFKALGVD
>Mature_679_residues
MDTQLNCSLDSLLNQHFAGKVVRKDLTKLVKEGANVPVYVLEYLLGMYCASDNEEVIQDGLVNVKKILAENYVRPDEAEK
VKSKIRELGTYKVIDKVTVKLNEKRDTYEALLSNLGVKGVEIASGTVKKYEKLLVGGIWCIVTLNYFYEENMKGSPFSIG
DLKPIQMPNMDMEGLFEGRKAFSQEQWMDVLVRSTGMEPSVLEQRVKWHLIARMIPFVENGYNLCELGPRGTGKSHIYKE
ISPNSILVSGGQTTVANLFYNMGSHQVGLVGMWDVVAFDEVAGISFKDKDGVQIMKDYMASGSFARGKDQISANAAMVFV
GNINQPVDTLVKTSHLLAPFPESMIDSAFFDRFHCYIPGWEVPKMRPEFFTNQYGLIVDYLAEYLREMRKYNFSDAIDKF
FKLGNNLNQRDTIAVRRTVSGLLKLLYPHGEFDKEAVRQCLHYALEVRRRIKEQLKKIGGMEFYDVHFSYIDNESMEERF
IGVPEQGGSSLIPEGQLKPGTLHTVSTGSGGMLGLYRLELQVIGGNGKLSLSGFGTSQNAKEPVKVAFDYFKANLTRVSG
IAKAIDHDYHMHMVELHNTGPASALTIASFVCFCSGLLGKPIQSQMVILGDMSLGGSIIPAENLAESLQVAFDAGAKRIL
IPMSSVKDIPTIPGELFAKFQTSFYADPVDAVFKALGVD

Specific function: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced

COG id: COG4930

COG function: function code O; Predicted ATP-dependent Lon-type protease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Lon domain [H]

Homologues:

None

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008269
- InterPro:   IPR004815
- InterPro:   IPR003111
- InterPro:   IPR008268
- InterPro:   IPR001984
- InterPro:   IPR015947
- InterPro:   IPR020568 [H]

Pfam domain/function: PF00004 AAA; PF02190 LON; PF05362 Lon_C [H]

EC number: =3.4.21.53 [H]

Molecular weight: Translated: 75539; Mature: 75539

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTQLNCSLDSLLNQHFAGKVVRKDLTKLVKEGANVPVYVLEYLLGMYCASDNEEVIQDG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHH
LVNVKKILAENYVRPDEAEKVKSKIRELGTYKVIDKVTVKLNEKRDTYEALLSNLGVKGV
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHEEEEECCCCHHHHHHHHHCCCCCE
EIASGTVKKYEKLLVGGIWCIVTLNYFYEENMKGSPFSIGDLKPIQMPNMDMEGLFEGRK
EECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
AFSQEQWMDVLVRSTGMEPSVLEQRVKWHLIARMIPFVENGYNLCELGPRGTGKSHIYKE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHC
ISPNSILVSGGQTTVANLFYNMGSHQVGLVGMWDVVAFDEVAGISFKDKDGVQIMKDYMA
CCCCEEEEECCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
SGSFARGKDQISANAAMVFVGNINQPVDTLVKTSHLLAPFPESMIDSAFFDRFHCYIPGW
CCCCCCCCHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCEEEECCCC
EVPKMRPEFFTNQYGLIVDYLAEYLREMRKYNFSDAIDKFFKLGNNLNQRDTIAVRRTVS
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
GLLKLLYPHGEFDKEAVRQCLHYALEVRRRIKEQLKKIGGMEFYDVHFSYIDNESMEERF
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHH
IGVPEQGGSSLIPEGQLKPGTLHTVSTGSGGMLGLYRLELQVIGGNGKLSLSGFGTSQNA
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEEEEEECCCCEEEEEECCCCCCC
KEPVKVAFDYFKANLTRVSGIAKAIDHDYHMHMVELHNTGPASALTIASFVCFCSGLLGK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCC
PIQSQMVILGDMSLGGSIIPAENLAESLQVAFDAGAKRILIPMSSVKDIPTIPGELFAKF
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEHHHCCCCCCCCHHHHHHH
QTSFYADPVDAVFKALGVD
HHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure
MDTQLNCSLDSLLNQHFAGKVVRKDLTKLVKEGANVPVYVLEYLLGMYCASDNEEVIQDG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHH
LVNVKKILAENYVRPDEAEKVKSKIRELGTYKVIDKVTVKLNEKRDTYEALLSNLGVKGV
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHEEEEECCCCHHHHHHHHHCCCCCE
EIASGTVKKYEKLLVGGIWCIVTLNYFYEENMKGSPFSIGDLKPIQMPNMDMEGLFEGRK
EECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
AFSQEQWMDVLVRSTGMEPSVLEQRVKWHLIARMIPFVENGYNLCELGPRGTGKSHIYKE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHC
ISPNSILVSGGQTTVANLFYNMGSHQVGLVGMWDVVAFDEVAGISFKDKDGVQIMKDYMA
CCCCEEEEECCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
SGSFARGKDQISANAAMVFVGNINQPVDTLVKTSHLLAPFPESMIDSAFFDRFHCYIPGW
CCCCCCCCHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCEEEECCCC
EVPKMRPEFFTNQYGLIVDYLAEYLREMRKYNFSDAIDKFFKLGNNLNQRDTIAVRRTVS
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
GLLKLLYPHGEFDKEAVRQCLHYALEVRRRIKEQLKKIGGMEFYDVHFSYIDNESMEERF
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHH
IGVPEQGGSSLIPEGQLKPGTLHTVSTGSGGMLGLYRLELQVIGGNGKLSLSGFGTSQNA
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEEEEEECCCCEEEEEECCCCCCC
KEPVKVAFDYFKANLTRVSGIAKAIDHDYHMHMVELHNTGPASALTIASFVCFCSGLLGK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCC
PIQSQMVILGDMSLGGSIIPAENLAESLQVAFDAGAKRILIPMSSVKDIPTIPGELFAKF
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEHHHCCCCCCCCHHHHHHH
QTSFYADPVDAVFKALGVD
HHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA