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The map label for this gene is tadA [H]

Identifier: 118580679

GI number: 118580679

Start: 2443736

End: 2444281

Strand: Reverse

Name: tadA [H]

Synonym: Ppro_2264

Alternate gene names: 118580679

Gene position: 2444281-2443736 (Counterclockwise)

Preceding gene: 118580680

Following gene: 118580678

Centisome position: 60.99

GC content: 63.92

Gene sequence:

>546_bases
ATGCCGGTCATGATCGTGGAAAAGAAGAGTATCGCCCGCAGCCACGAGTACTGGATGCAGCGGGCCATAGCCGAGGCGGG
CAAGGCCCGCAGCAGGGACGAGGTCCCCATCGGCTGCGTGATCGTCAGGGACAACAGGATTATCGCCCGCGGCCACAACC
TGCGGGAGAGTTCCCAGGACCCTTCCGCCCATGCCGAGATGATCGCCATACGCAAGGCAGCCCGAAAGCTCTCCTCCTGG
CGACTCCTGGACACCACCCTCTATGTAACCCTGGAACCCTGCACCATGTGCATGGGCGCCATCATCCTTTCGCGCATCCC
CCGCGTCGTGTTCGGCTGCCTGGACCCCAAGGGGGGGGCGGCCGGTTCGCTCTACGATCTCTCCAACGATCCCCGTCTCA
ATCATCGTGTGGAACTGCTGCCCGGCGTGCTGGAGCGCGATTGCTCGTCGCTTTTGAGCGGCTTCTTCGCCGAGTTGAGG
AGGCGCAGGCGTGAGGCGCGCCTTAGCTCCGCTGGAGAGCTTCCCGGAACTCCACAGGGCTGTTGA

Upstream 100 bases:

>100_bases
GGGCTTTCTGTTGGTCAGCTACCTCATGACCAGGTAGCATGACGTGCCGTGACCCCTCCCCCAGGATTCCCTTTGCCCGT
TTCCCCCCTCTGTGGTATAG

Downstream 100 bases:

>100_bases
TGTTGCGGAACGACACTCCGGCGCCGGGAATGGAGCGGATCACCTGTCGGGGGATCACGCCGGTCACCCCACCAATCCTG
GCGCTGTCCGTCACGGGGAG

Product: CMP/dCMP deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MPVMIVEKKSIARSHEYWMQRAIAEAGKARSRDEVPIGCVIVRDNRIIARGHNLRESSQDPSAHAEMIAIRKAARKLSSW
RLLDTTLYVTLEPCTMCMGAIILSRIPRVVFGCLDPKGGAAGSLYDLSNDPRLNHRVELLPGVLERDCSSLLSGFFAELR
RRRREARLSSAGELPGTPQGC

Sequences:

>Translated_181_residues
MPVMIVEKKSIARSHEYWMQRAIAEAGKARSRDEVPIGCVIVRDNRIIARGHNLRESSQDPSAHAEMIAIRKAARKLSSW
RLLDTTLYVTLEPCTMCMGAIILSRIPRVVFGCLDPKGGAAGSLYDLSNDPRLNHRVELLPGVLERDCSSLLSGFFAELR
RRRREARLSSAGELPGTPQGC
>Mature_180_residues
PVMIVEKKSIARSHEYWMQRAIAEAGKARSRDEVPIGCVIVRDNRIIARGHNLRESSQDPSAHAEMIAIRKAARKLSSWR
LLDTTLYVTLEPCTMCMGAIILSRIPRVVFGCLDPKGGAAGSLYDLSNDPRLNHRVELLPGVLERDCSSLLSGFFAELRR
RRREARLSSAGELPGTPQGC

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=155, Percent_Identity=32.258064516129, Blast_Score=100, Evalue=1e-21,
Organism=Escherichia coli, GI145693172, Length=154, Percent_Identity=51.9480519480519, Blast_Score=165, Evalue=2e-42,
Organism=Escherichia coli, GI1786616, Length=154, Percent_Identity=31.8181818181818, Blast_Score=65, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17554608, Length=96, Percent_Identity=40.625, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17541138, Length=145, Percent_Identity=31.7241379310345, Blast_Score=85, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17555996, Length=130, Percent_Identity=32.3076923076923, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6322425, Length=169, Percent_Identity=31.9526627218935, Blast_Score=79, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6325319, Length=96, Percent_Identity=39.5833333333333, Blast_Score=70, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355527, Length=145, Percent_Identity=31.7241379310345, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 20112; Mature: 19980

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVMIVEKKSIARSHEYWMQRAIAEAGKARSRDEVPIGCVIVRDNRIIARGHNLRESSQD
CCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCEEEECCCCCCCCCCC
PSAHAEMIAIRKAARKLSSWRLLDTTLYVTLEPCTMCMGAIILSRIPRVVFGCLDPKGGA
CHHHHHHHHHHHHHHHHHCCEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCC
AGSLYDLSNDPRLNHRVELLPGVLERDCSSLLSGFFAELRRRRREARLSSAGELPGTPQG
CCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
C
C
>Mature Secondary Structure 
PVMIVEKKSIARSHEYWMQRAIAEAGKARSRDEVPIGCVIVRDNRIIARGHNLRESSQD
CEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCEEEECCCCCCCCCCC
PSAHAEMIAIRKAARKLSSWRLLDTTLYVTLEPCTMCMGAIILSRIPRVVFGCLDPKGGA
CHHHHHHHHHHHHHHHHHCCEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCC
AGSLYDLSNDPRLNHRVELLPGVLERDCSSLLSGFFAELRRRRREARLSSAGELPGTPQG
CCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
C
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]