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The map label for this gene is rarA [H]

Identifier: 118580657

GI number: 118580657

Start: 2422521

End: 2423867

Strand: Direct

Name: rarA [H]

Synonym: Ppro_2242

Alternate gene names: 118580657

Gene position: 2422521-2423867 (Clockwise)

Preceding gene: 118580656

Following gene: 118580658

Centisome position: 60.44

GC content: 64.96

Gene sequence:

>1347_bases
ATGAAACAGAACAACACACCCGGCCTCTGGGACAGGGACCAGGGGGAATCCACGGCCGCCCCCTCCGCCAACGCCCCCCT
GGCCGAACGGATGCGGCCGCGCACCCTGACGGAGTTCACCGGCCAGGAACATCTGGTGGGCGAGGACCGCATCCTGCGGC
GCATGATCGAGACCGACACCCTCTCCTCGCTGATCTTCTGGGGACCTCCCGGATGCGGCAAGACCACCCTGGCCCATGTC
ATCGCCCGGGAGACACGGGCGCACTTCATCTTCTTCTCGGCCATCCTGTCCGGCATCAAGGAGATCAGGGAGATCTTCCG
CGAGGCCGAGGGGGTGGCCAGCCGTGGCCGGCGCACGATCCTGTTCGTGGACGAGATCCATCGCTTCAACAAATCCCAGC
AGGACGCCTTTCTCCCCTATGTGGAAAAAGGGGTAGTCACCATGATCGGCGCCACCACCGAGAACCCCTCCTTCGAGGTC
ATCGCCCCGCTGCTCTCCCGCTGTCGCGTGCTGACCCTGAAACAACTGGAGCCGTCCACCATCGCGGGGCTCATCGGCCA
GGCACTGGCCGACCGGGAGCGGGGACTGGGGGAACTGGGGCTAGACATTTCCGAAGAAGGGCTGGACTTCCTGTCCCGGC
AGGCCGGCGGCGACGCGCGCGTGGCCCTGAACACCCTGGAGGTCGCGGCGGGCCTGGCCCGGGAGAGGCTGATCTCCCTG
GAGACGGTCCAGGAGGCGCTGCAGAAGAAGGCGCTCCTGTACGACAAGAGGGGCGAAGAGCACTACAACGTGATCTCCGC
TTTCATCAAGTCCATGCGCGCCAGTGACCCGGACGCGGCCCTGTACTGGCTGGCCCGCATGCTGGAGGCGGGAGAGGATC
CGGTCTTCATCCTGCGGCGCATGATCATCCTGGCGTCGGAAGACATCGGCAATGCCGACCCGCGCGCCCTCCAGCTGGCT
GTTTCAGCCCTGCAGGCCTTCCAGGTGATCGGCATGCCCGAGGGGCGCATAATCATGGCCCAGGCGGTCACCTATCTGGC
CACCGCCCCCAAGTCCAACGCCTCCTACCTGGGCATCGACGCTACCCTGGCCGAGGTCAGGAAGAGCGGCGGCCTGGGGG
TGCCGATGCATATCCGCAACGCCCCCACCACGCTGATGAAGGACCTGGGCTACGGCAAGGGGTACCAGTACGCCCACGAC
TATGCCGAAGGGTATGCCGGCCAGCCCTGCCTGCCGGACGAACTGGCCGGACGCACGTTCTACGAACCAAAGGGGTATGG
ATACGAGAAGAGCATCGTGGAACGCATGGAGTGGCTGAAGAGGATCAAGGAGGAAAGAAAAAAATGA

Upstream 100 bases:

>100_bases
GCCGGTGGGAAGACGAACACATACGGAACTTTTTTAATCGGCTTGGCCACAAAAGAGGGCGCCCCTGAGGTCAAGCCCGA
CAGACTCCTAGAGCACTCGC

Downstream 100 bases:

>100_bases
AACCGTTCACCCTTGAGCGCAGCCAGATTCTTCCGGTGAGCCAGGACGAGGCCTGGAGGTTCTTCTCCGATCCGGCCAAC
CTGGGCAACATCACCCCCCC

Product: recombination factor protein RarA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MKQNNTPGLWDRDQGESTAAPSANAPLAERMRPRTLTEFTGQEHLVGEDRILRRMIETDTLSSLIFWGPPGCGKTTLAHV
IARETRAHFIFFSAILSGIKEIREIFREAEGVASRGRRTILFVDEIHRFNKSQQDAFLPYVEKGVVTMIGATTENPSFEV
IAPLLSRCRVLTLKQLEPSTIAGLIGQALADRERGLGELGLDISEEGLDFLSRQAGGDARVALNTLEVAAGLARERLISL
ETVQEALQKKALLYDKRGEEHYNVISAFIKSMRASDPDAALYWLARMLEAGEDPVFILRRMIILASEDIGNADPRALQLA
VSALQAFQVIGMPEGRIIMAQAVTYLATAPKSNASYLGIDATLAEVRKSGGLGVPMHIRNAPTTLMKDLGYGKGYQYAHD
YAEGYAGQPCLPDELAGRTFYEPKGYGYEKSIVERMEWLKRIKEERKK

Sequences:

>Translated_448_residues
MKQNNTPGLWDRDQGESTAAPSANAPLAERMRPRTLTEFTGQEHLVGEDRILRRMIETDTLSSLIFWGPPGCGKTTLAHV
IARETRAHFIFFSAILSGIKEIREIFREAEGVASRGRRTILFVDEIHRFNKSQQDAFLPYVEKGVVTMIGATTENPSFEV
IAPLLSRCRVLTLKQLEPSTIAGLIGQALADRERGLGELGLDISEEGLDFLSRQAGGDARVALNTLEVAAGLARERLISL
ETVQEALQKKALLYDKRGEEHYNVISAFIKSMRASDPDAALYWLARMLEAGEDPVFILRRMIILASEDIGNADPRALQLA
VSALQAFQVIGMPEGRIIMAQAVTYLATAPKSNASYLGIDATLAEVRKSGGLGVPMHIRNAPTTLMKDLGYGKGYQYAHD
YAEGYAGQPCLPDELAGRTFYEPKGYGYEKSIVERMEWLKRIKEERKK
>Mature_448_residues
MKQNNTPGLWDRDQGESTAAPSANAPLAERMRPRTLTEFTGQEHLVGEDRILRRMIETDTLSSLIFWGPPGCGKTTLAHV
IARETRAHFIFFSAILSGIKEIREIFREAEGVASRGRRTILFVDEIHRFNKSQQDAFLPYVEKGVVTMIGATTENPSFEV
IAPLLSRCRVLTLKQLEPSTIAGLIGQALADRERGLGELGLDISEEGLDFLSRQAGGDARVALNTLEVAAGLARERLISL
ETVQEALQKKALLYDKRGEEHYNVISAFIKSMRASDPDAALYWLARMLEAGEDPVFILRRMIILASEDIGNADPRALQLA
VSALQAFQVIGMPEGRIIMAQAVTYLATAPKSNASYLGIDATLAEVRKSGGLGVPMHIRNAPTTLMKDLGYGKGYQYAHD
YAEGYAGQPCLPDELAGRTFYEPKGYGYEKSIVERMEWLKRIKEERKK

Specific function: Unknown

COG id: COG2256

COG function: function code L; ATPase related to the helicase subunit of the Holliday junction resolvase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rarA family [H]

Homologues:

Organism=Homo sapiens, GI18426902, Length=438, Percent_Identity=47.2602739726027, Blast_Score=380, Evalue=1e-105,
Organism=Homo sapiens, GI18426904, Length=438, Percent_Identity=43.1506849315069, Blast_Score=325, Evalue=6e-89,
Organism=Homo sapiens, GI4506491, Length=244, Percent_Identity=27.4590163934426, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI31881687, Length=244, Percent_Identity=27.4590163934426, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI6677723, Length=226, Percent_Identity=26.1061946902655, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1787119, Length=420, Percent_Identity=49.5238095238095, Blast_Score=407, Evalue=1e-115,
Organism=Escherichia coli, GI1788167, Length=215, Percent_Identity=27.4418604651163, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17541988, Length=327, Percent_Identity=25.9938837920489, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71986063, Length=246, Percent_Identity=26.8292682926829, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324111, Length=425, Percent_Identity=40.7058823529412, Blast_Score=303, Evalue=3e-83,
Organism=Saccharomyces cerevisiae, GI6324039, Length=277, Percent_Identity=24.5487364620939, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI18859927, Length=241, Percent_Identity=24.896265560166, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17647857, Length=284, Percent_Identity=26.7605633802817, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR021886 [H]

Pfam domain/function: PF00004 AAA; PF12002 MgsA_C [H]

EC number: NA

Molecular weight: Translated: 49646; Mature: 49646

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQNNTPGLWDRDQGESTAAPSANAPLAERMRPRTLTEFTGQEHLVGEDRILRRMIETDT
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHHHH
LSSLIFWGPPGCGKTTLAHVIARETRAHFIFFSAILSGIKEIREIFREAEGVASRGRRTI
HHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LFVDEIHRFNKSQQDAFLPYVEKGVVTMIGATTENPSFEVIAPLLSRCRVLTLKQLEPST
EEHHHHHHHCCCCCCCCCHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHH
IAGLIGQALADRERGLGELGLDISEEGLDFLSRQAGGDARVALNTLEVAAGLARERLISL
HHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ETVQEALQKKALLYDKRGEEHYNVISAFIKSMRASDPDAALYWLARMLEAGEDPVFILRR
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHH
MIILASEDIGNADPRALQLAVSALQAFQVIGMPEGRIIMAQAVTYLATAPKSNASYLGID
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCCCCEEEHH
ATLAEVRKSGGLGVPMHIRNAPTTLMKDLGYGKGYQYAHDYAEGYAGQPCLPDELAGRTF
HHHHHHHHCCCCCCCEEECCCCHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCHHHCCCCC
YEPKGYGYEKSIVERMEWLKRIKEERKK
CCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKQNNTPGLWDRDQGESTAAPSANAPLAERMRPRTLTEFTGQEHLVGEDRILRRMIETDT
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHHHH
LSSLIFWGPPGCGKTTLAHVIARETRAHFIFFSAILSGIKEIREIFREAEGVASRGRRTI
HHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LFVDEIHRFNKSQQDAFLPYVEKGVVTMIGATTENPSFEVIAPLLSRCRVLTLKQLEPST
EEHHHHHHHCCCCCCCCCHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHH
IAGLIGQALADRERGLGELGLDISEEGLDFLSRQAGGDARVALNTLEVAAGLARERLISL
HHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ETVQEALQKKALLYDKRGEEHYNVISAFIKSMRASDPDAALYWLARMLEAGEDPVFILRR
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHH
MIILASEDIGNADPRALQLAVSALQAFQVIGMPEGRIIMAQAVTYLATAPKSNASYLGID
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCCCCEEEHH
ATLAEVRKSGGLGVPMHIRNAPTTLMKDLGYGKGYQYAHDYAEGYAGQPCLPDELAGRTF
HHHHHHHHCCCCCCCEEECCCCHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCHHHCCCCC
YEPKGYGYEKSIVERMEWLKRIKEERKK
CCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12704232 [H]