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The map label for this gene is dhaR [H]

Identifier: 118580630

GI number: 118580630

Start: 2391651

End: 2392298

Strand: Reverse

Name: dhaR [H]

Synonym: Ppro_2215

Alternate gene names: 118580630

Gene position: 2392298-2391651 (Counterclockwise)

Preceding gene: 118580631

Following gene: 118580629

Centisome position: 59.69

GC content: 59.72

Gene sequence:

>648_bases
ATGCCGTTTCCGGGGGATTTCCTTGACAGGTTAGACTGCCCAGTCTATTTTATGCCCATGGCAAAACGAGATACACGAAG
CGAAATCGTCAAGATCGGCACCGACCTGATCAGCCGCAACGGGTACAACGCCACCGGAATCGACGCGGTGCTCAGGGAAG
CCGGCATACCCAAGGGATCGTTCTACCACTACTTCAAGAGCAAAGAGGAGTTCGGCCTGGCGGTGATCGACCACTTTGCC
GAGCGCTATGACCAGCGACTGGAAACCTTCCTGGCTGATGAAGAGGTGACGCCCCTCAACCGCATCCGCAACTATCTGGA
GAGCGGCCTTGTGCGGCTGGAGCAGAACCTCTGTACCAGGGGATGTCTGGTGGGCAATCTGGGGCAGGAACTGGCGGACA
GCAACGAGCGGTTCCGCTCCCGCCTGGACCAGATCTTCACCTCCTGGAAGGAACGCTTCGCCGCCTGTCTGGTGGAGGCG
CAGGCGGCGGGTGAACTGTCGGGAGAGGTTGACCCCCAGGTTCTGGCCTGTTTCATCCTCTCCGGGTGGGAGGGGGCCAT
CCTGCGGGCCAAGGTGATGAAGTCGCCGCAACCGATCCGGGATTTCATCCAGATCCTGTTTGCGACGGTGCTTCGTTCTC
AGCAGTAG

Upstream 100 bases:

>100_bases
GATCAACGGCAGCGGAGGCGCGGTCGGGGAATGCCGCTCCACCTTGAACCCCCAGGGGGAACAGCCGATCGTTTCCAGAG
CGTCCAGCAGGCGGGGGATG

Downstream 100 bases:

>100_bases
AGCGGCCCGGTCGGCAGTCCGACAAGGACATGACGTCCCCGGTCGTGGTAATCGCCGCCAGTCTAGACGACTGGTCTAAT
TCATACACAAGGAGCCGGAC

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MPFPGDFLDRLDCPVYFMPMAKRDTRSEIVKIGTDLISRNGYNATGIDAVLREAGIPKGSFYHYFKSKEEFGLAVIDHFA
ERYDQRLETFLADEEVTPLNRIRNYLESGLVRLEQNLCTRGCLVGNLGQELADSNERFRSRLDQIFTSWKERFAACLVEA
QAAGELSGEVDPQVLACFILSGWEGAILRAKVMKSPQPIRDFIQILFATVLRSQQ

Sequences:

>Translated_215_residues
MPFPGDFLDRLDCPVYFMPMAKRDTRSEIVKIGTDLISRNGYNATGIDAVLREAGIPKGSFYHYFKSKEEFGLAVIDHFA
ERYDQRLETFLADEEVTPLNRIRNYLESGLVRLEQNLCTRGCLVGNLGQELADSNERFRSRLDQIFTSWKERFAACLVEA
QAAGELSGEVDPQVLACFILSGWEGAILRAKVMKSPQPIRDFIQILFATVLRSQQ
>Mature_214_residues
PFPGDFLDRLDCPVYFMPMAKRDTRSEIVKIGTDLISRNGYNATGIDAVLREAGIPKGSFYHYFKSKEEFGLAVIDHFAE
RYDQRLETFLADEEVTPLNRIRNYLESGLVRLEQNLCTRGCLVGNLGQELADSNERFRSRLDQIFTSWKERFAACLVEAQ
AAGELSGEVDPQVLACFILSGWEGAILRAKVMKSPQPIRDFIQILFATVLRSQQ

Specific function: Transcriptional repressor for the dhaA haloalkane dehalogenase gene [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693141, Length=182, Percent_Identity=31.3186813186813, Blast_Score=96, Evalue=1e-21,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 24408; Mature: 24277

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFPGDFLDRLDCPVYFMPMAKRDTRSEIVKIGTDLISRNGYNATGIDAVLREAGIPKGS
CCCCHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCH
FYHYFKSKEEFGLAVIDHFAERYDQRLETFLADEEVTPLNRIRNYLESGLVRLEQNLCTR
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GCLVGNLGQELADSNERFRSRLDQIFTSWKERFAACLVEAQAAGELSGEVDPQVLACFIL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
SGWEGAILRAKVMKSPQPIRDFIQILFATVLRSQQ
HCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PFPGDFLDRLDCPVYFMPMAKRDTRSEIVKIGTDLISRNGYNATGIDAVLREAGIPKGS
CCCHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCH
FYHYFKSKEEFGLAVIDHFAERYDQRLETFLADEEVTPLNRIRNYLESGLVRLEQNLCTR
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GCLVGNLGQELADSNERFRSRLDQIFTSWKERFAACLVEAQAAGELSGEVDPQVLACFIL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
SGWEGAILRAKVMKSPQPIRDFIQILFATVLRSQQ
HCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10735862 [H]