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The map label for this gene is arpC [H]

Identifier: 118580620

GI number: 118580620

Start: 2380467

End: 2381882

Strand: Direct

Name: arpC [H]

Synonym: Ppro_2205

Alternate gene names: 118580620

Gene position: 2380467-2381882 (Clockwise)

Preceding gene: 118580619

Following gene: 118580621

Centisome position: 59.39

GC content: 66.95

Gene sequence:

>1416_bases
ATGAAACCGATACTGCCCGTTGCCATGGCTACGCTGCTCTTGGCCTGCAGCGTGGGACCTGACTATGTCAGGCCGACCGC
GGTCGTGCCGGCCGCATTCGGGGAGAGCGCCCCCTGGAGGGTTGCCCAGCCCCGCGACAACGCCCAGCGTGGTCCCTGGT
GGCATATCTACGAAGACCCTCGCCTGAACGGGCTGATGGAACAGGTTACGCTTTCCAACCAGTCGCTCAAGGCCGCCGAG
GCGCAGTTCCGCCAGGCGAGAGCCCTTGTCCAGGCCGCCCGCTCCGGTTATCATCCCCAGCTGCACGGGGGAGCGTCGCT
GGATCGTTCCCGGAGCTATTCCAAAAACAGTGGGTCAACCTCCACGACCTACCTGCTCTCAGCCGATGCCTCCTGGGAAC
TGGACCTGTGGGGACGGGTGCGCCGCGACGTCGAGGCCAGCCGGGCCGAGGCCCAGGCCAGCGCGGCCGACCTGGAATCG
CTGCGTTTGAGTATCCAGGCGGAACTGGTGGGAGACTACTTCCAGCTGCGAACCATCGACGCCCAGAAACGGCTCCTGGA
CGAGACCGTCTCCTCCTACGAGCAGTACCTGGAGCTGACCAGAAACCGCCATGCGGCCGGCGTGGCCTCCCCGGCCGACG
TGCTCCAGGCCGAGACCCAGCTGAGGAACAGCCAGGCCCAGGCAATCGACCTGGGAGTGGAGCGCGCCCAACGGGAGCAC
GCCATTGCGCTTCTGATCGGCAGGGCCCCGGCCGAGTTCACCCTGACGCCCATTCCCCTGGACAGCATCCCTCCCCCTTC
ACCTCCCGGCCTGCCGTCCCGGCTCCTGGAACGCAGGCCGGACATAGCGGCGGCCGAGCGGCGGGTTGCTGCGGCCAATG
CCCGCATCGGCGTCGCCACGGCAGCCTACTTCCCCGCCATTACCTTGAGCTCTTCCGCCGGCTTCGCCTCATCGAGCCTT
TCCAACTGGCTGAGTTGGCCCGGCCATGTCTGGGCCCTGGGGAGCGCCATCGCCCAGACCGTCTATGACGGCGGCCTGCG
AGGGGCGCAGGTGGACGAGGCCCGGGCAACCCATGAAGCCACGGTGGCCAACTACCGCCAGACGGTCCTGACCGCCTTCC
AAGAGGTAGAAGACAACCTGGCCGCGCTGCGTATCCTGGAGCAGGAGGCGGCAGTGCAGGATCAGGCGCTGCGGGCGGCA
CGCCAGTCGCTGGTAATCACCACCAACCAGTACCGTGCCGGGATCGTCGGCTATCTCAACGTCATCGTCGCCCAGACAAC
CGCCCTTGAACTGGAGCGGGACAGCATCGACCTCATGGGACGGCGCATGGCGGCCAGCGTGAATCTGGTCAAGGGGATCG
GGGGTGGCTGGGATGCCGCTGACCTGGCGGCGATTGACGGGAACGGACAGCAATAG

Upstream 100 bases:

>100_bases
TCTACCTGTACATGGACCGTTTCAGGATCTGGCTTGACCGGAAGAGGAAGCGGCGGTTTTCCACTGACGCAACTGCACAG
GATGTCAACCTATGAAAAAC

Downstream 100 bases:

>100_bases
TACTACTGGAGAGATGAAACCATTCTGCTTCTCATCCAGCGATCTGAAGTTTCTGCTGCGCGCCCTGCATTCCCGCAACT
ACCGGCTCTTCTTCATTGGA

Product: RND efflux system outer membrane lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MKPILPVAMATLLLACSVGPDYVRPTAVVPAAFGESAPWRVAQPRDNAQRGPWWHIYEDPRLNGLMEQVTLSNQSLKAAE
AQFRQARALVQAARSGYHPQLHGGASLDRSRSYSKNSGSTSTTYLLSADASWELDLWGRVRRDVEASRAEAQASAADLES
LRLSIQAELVGDYFQLRTIDAQKRLLDETVSSYEQYLELTRNRHAAGVASPADVLQAETQLRNSQAQAIDLGVERAQREH
AIALLIGRAPAEFTLTPIPLDSIPPPSPPGLPSRLLERRPDIAAAERRVAAANARIGVATAAYFPAITLSSSAGFASSSL
SNWLSWPGHVWALGSAIAQTVYDGGLRGAQVDEARATHEATVANYRQTVLTAFQEVEDNLAALRILEQEAAVQDQALRAA
RQSLVITTNQYRAGIVGYLNVIVAQTTALELERDSIDLMGRRMAASVNLVKGIGGGWDAADLAAIDGNGQQ

Sequences:

>Translated_471_residues
MKPILPVAMATLLLACSVGPDYVRPTAVVPAAFGESAPWRVAQPRDNAQRGPWWHIYEDPRLNGLMEQVTLSNQSLKAAE
AQFRQARALVQAARSGYHPQLHGGASLDRSRSYSKNSGSTSTTYLLSADASWELDLWGRVRRDVEASRAEAQASAADLES
LRLSIQAELVGDYFQLRTIDAQKRLLDETVSSYEQYLELTRNRHAAGVASPADVLQAETQLRNSQAQAIDLGVERAQREH
AIALLIGRAPAEFTLTPIPLDSIPPPSPPGLPSRLLERRPDIAAAERRVAAANARIGVATAAYFPAITLSSSAGFASSSL
SNWLSWPGHVWALGSAIAQTVYDGGLRGAQVDEARATHEATVANYRQTVLTAFQEVEDNLAALRILEQEAAVQDQALRAA
RQSLVITTNQYRAGIVGYLNVIVAQTTALELERDSIDLMGRRMAASVNLVKGIGGGWDAADLAAIDGNGQQ
>Mature_471_residues
MKPILPVAMATLLLACSVGPDYVRPTAVVPAAFGESAPWRVAQPRDNAQRGPWWHIYEDPRLNGLMEQVTLSNQSLKAAE
AQFRQARALVQAARSGYHPQLHGGASLDRSRSYSKNSGSTSTTYLLSADASWELDLWGRVRRDVEASRAEAQASAADLES
LRLSIQAELVGDYFQLRTIDAQKRLLDETVSSYEQYLELTRNRHAAGVASPADVLQAETQLRNSQAQAIDLGVERAQREH
AIALLIGRAPAEFTLTPIPLDSIPPPSPPGLPSRLLERRPDIAAAERRVAAANARIGVATAAYFPAITLSSSAGFASSSL
SNWLSWPGHVWALGSAIAQTVYDGGLRGAQVDEARATHEATVANYRQTVLTAFQEVEDNLAALRILEQEAAVQDQALRAA
RQSLVITTNQYRAGIVGYLNVIVAQTTALELERDSIDLMGRRMAASVNLVKGIGGGWDAADLAAIDGNGQQ

Specific function: The outer membrane component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin, chloramphenicol, erythromycin, novobiocin, streptomycin and tetracycline. Is not involved in organic solven

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=464, Percent_Identity=30.1724137931034, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI2367348, Length=424, Percent_Identity=24.0566037735849, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 50832; Mature: 50832

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPILPVAMATLLLACSVGPDYVRPTAVVPAAFGESAPWRVAQPRDNAQRGPWWHIYEDP
CCCCHHHHHHHHHHHHCCCCCCCCCCEEEEHHCCCCCCCCCCCCCCCCCCCCEEEEECCC
RLNGLMEQVTLSNQSLKAAEAQFRQARALVQAARSGYHPQLHGGASLDRSRSYSKNSGST
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
STTYLLSADASWELDLWGRVRRDVEASRAEAQASAADLESLRLSIQAELVGDYFQLRTID
CEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEECC
AQKRLLDETVSSYEQYLELTRNRHAAGVASPADVLQAETQLRNSQAQAIDLGVERAQREH
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
AIALLIGRAPAEFTLTPIPLDSIPPPSPPGLPSRLLERRPDIAAAERRVAAANARIGVAT
EEEEEEECCCCCEEEECCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCEEHH
AAYFPAITLSSSAGFASSSLSNWLSWPGHVWALGSAIAQTVYDGGLRGAQVDEARATHEA
HHHHCEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
TVANYRQTVLTAFQEVEDNLAALRILEQEAAVQDQALRAARQSLVITTNQYRAGIVGYLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCHHHHHHHHHH
VIVAQTTALELERDSIDLMGRRMAASVNLVKGIGGGWDAADLAAIDGNGQQ
HHHHHHHHEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCC
>Mature Secondary Structure
MKPILPVAMATLLLACSVGPDYVRPTAVVPAAFGESAPWRVAQPRDNAQRGPWWHIYEDP
CCCCHHHHHHHHHHHHCCCCCCCCCCEEEEHHCCCCCCCCCCCCCCCCCCCCEEEEECCC
RLNGLMEQVTLSNQSLKAAEAQFRQARALVQAARSGYHPQLHGGASLDRSRSYSKNSGST
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
STTYLLSADASWELDLWGRVRRDVEASRAEAQASAADLESLRLSIQAELVGDYFQLRTID
CEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEECC
AQKRLLDETVSSYEQYLELTRNRHAAGVASPADVLQAETQLRNSQAQAIDLGVERAQREH
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
AIALLIGRAPAEFTLTPIPLDSIPPPSPPGLPSRLLERRPDIAAAERRVAAANARIGVAT
EEEEEEECCCCCEEEECCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCEEHH
AAYFPAITLSSSAGFASSSLSNWLSWPGHVWALGSAIAQTVYDGGLRGAQVDEARATHEA
HHHHCEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
TVANYRQTVLTAFQEVEDNLAALRILEQEAAVQDQALRAARQSLVITTNQYRAGIVGYLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCHHHHHHHHHH
VIVAQTTALELERDSIDLMGRRMAASVNLVKGIGGGWDAADLAAIDGNGQQ
HHHHHHHHEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11160799 [H]