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The map label for this gene is mdtA [H]

Identifier: 118580617

GI number: 118580617

Start: 2373045

End: 2374268

Strand: Direct

Name: mdtA [H]

Synonym: Ppro_2202

Alternate gene names: 118580617

Gene position: 2373045-2374268 (Clockwise)

Preceding gene: 118580616

Following gene: 118580618

Centisome position: 59.21

GC content: 64.38

Gene sequence:

>1224_bases
ATGAGCACCGACACACCTATACCTGTTCCCCAGCCCCCTTCTCGCAGGCGATGGCTGTTCCTGTTCTCCCTGATCTGCCT
GGCTTTGGCGGGAACCTACATGCTCGTCAGCAGGGATCCCGACGCAAACGACGGCACAAAAAAAACACCGCCGAGTCCGC
CGGTGGCGGTGGTGACCCAAGCGGCCAAAAAGAGCGACATCAGCGTCTACCTCACCGGCATCGGGACGGTAACGCCGCTG
AACACCGTCACTGTCAGGTCCCGCGTGGATGGCCAGCTAATGGAAGTGCTCTACCGCGAGGGGCAGACAGTAAGCCGAGG
ACAACTGCTGGCCAGGATCGACCCGCGCCCCTTTCAGGTGCTCTTGACCCAGGCCGAGGGACAGATGGCCCGCGACCAGG
CCCAGCTCTCCAATGCCCGGGTGGATCTCCAGCGCTACCGCACCCTCTGGGCACAGAACTCAATCCCCCGCCAGCAGCTG
GATACCCAGGAGGCGCTGGTGCGCCAGTACCAGGCGGCTGTCAAGAGCGACCAGGGTCAGGTGGACAGCGCGCGACTGCA
GCTGACCTACAGCCGCATCACCGCTCCCTGCGACGGACGTGTCGGCTTGCGGCTGGTGGATGCGGGCAATATCGTGCATG
CCAGCGACAGCGGCGGGCTGGTGGTGATCACCCGCATGCAGCCCATGACGGTGGTCTTCACCATCCCCGAGGACAACCTG
CCGCTGCTCGTGGACCGCATGAGGGGAGGCCGGAAACTGGCGGTGGATGCCTTTGACCGGGAGCAGAAACGGGTGCTTGC
CACAGGATCGCTCTTGACCCTGGACAACCAGATCGACCCCGGAACCGGCACGGTCAAGCTCAAGGCGATCTTCACCAACC
GTGACAACGAACTGTTCCCCAACCAGTTCGTCAATGCCCGCCTGCTAGTGGATGTCAGGCGGGATGCGATCACGGTGCCG
TCCGCCGCCATCCAGAACGGCCCCAAGGGCACATTCGTCTACCTGGTCAAGGGGAACAGGACGGTGGAACTGCGGCCGGT
GGAGAAAGGCGAGTCCGAGGGGGGGAAAACGGCCATCACCCGGGGGCTTGCCATTGGCGAGCAGGTGGTGGTGGACGGCG
CCGAGCGCCTGCGCGAAGGGAGCAGGGTTCAGATTAAACAGCCAGGGCAGGCTTCCGCGACTCCTGTGAGGCGGGACACA
AACCCCGCCCACGGCGCCCCATGA

Upstream 100 bases:

>100_bases
GGCGCGGGAAGACTATTCTCGTTGCCGCCCGCTGTTTTATATCACCGTCCTGTCAAAACGGCACGGCACGTATCCCATTG
GGAGGCTTCGTTTCATCATC

Downstream 100 bases:

>100_bases
ATATCTCCGCCCCCTTCATTCTGCGCCCGGTGGCCACCACCCTCCTGATGCTGGCCATCCTGCTGGCCGGGGCGATGGCC
TACACGCAGCTGCCGGTCTC

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MSTDTPIPVPQPPSRRRWLFLFSLICLALAGTYMLVSRDPDANDGTKKTPPSPPVAVVTQAAKKSDISVYLTGIGTVTPL
NTVTVRSRVDGQLMEVLYREGQTVSRGQLLARIDPRPFQVLLTQAEGQMARDQAQLSNARVDLQRYRTLWAQNSIPRQQL
DTQEALVRQYQAAVKSDQGQVDSARLQLTYSRITAPCDGRVGLRLVDAGNIVHASDSGGLVVITRMQPMTVVFTIPEDNL
PLLVDRMRGGRKLAVDAFDREQKRVLATGSLLTLDNQIDPGTGTVKLKAIFTNRDNELFPNQFVNARLLVDVRRDAITVP
SAAIQNGPKGTFVYLVKGNRTVELRPVEKGESEGGKTAITRGLAIGEQVVVDGAERLREGSRVQIKQPGQASATPVRRDT
NPAHGAP

Sequences:

>Translated_407_residues
MSTDTPIPVPQPPSRRRWLFLFSLICLALAGTYMLVSRDPDANDGTKKTPPSPPVAVVTQAAKKSDISVYLTGIGTVTPL
NTVTVRSRVDGQLMEVLYREGQTVSRGQLLARIDPRPFQVLLTQAEGQMARDQAQLSNARVDLQRYRTLWAQNSIPRQQL
DTQEALVRQYQAAVKSDQGQVDSARLQLTYSRITAPCDGRVGLRLVDAGNIVHASDSGGLVVITRMQPMTVVFTIPEDNL
PLLVDRMRGGRKLAVDAFDREQKRVLATGSLLTLDNQIDPGTGTVKLKAIFTNRDNELFPNQFVNARLLVDVRRDAITVP
SAAIQNGPKGTFVYLVKGNRTVELRPVEKGESEGGKTAITRGLAIGEQVVVDGAERLREGSRVQIKQPGQASATPVRRDT
NPAHGAP
>Mature_406_residues
STDTPIPVPQPPSRRRWLFLFSLICLALAGTYMLVSRDPDANDGTKKTPPSPPVAVVTQAAKKSDISVYLTGIGTVTPLN
TVTVRSRVDGQLMEVLYREGQTVSRGQLLARIDPRPFQVLLTQAEGQMARDQAQLSNARVDLQRYRTLWAQNSIPRQQLD
TQEALVRQYQAAVKSDQGQVDSARLQLTYSRITAPCDGRVGLRLVDAGNIVHASDSGGLVVITRMQPMTVVFTIPEDNLP
LLVDRMRGGRKLAVDAFDREQKRVLATGSLLTLDNQIDPGTGTVKLKAIFTNRDNELFPNQFVNARLLVDVRRDAITVPS
AAIQNGPKGTFVYLVKGNRTVELRPVEKGESEGGKTAITRGLAIGEQVVVDGAERLREGSRVQIKQPGQASATPVRRDTN
PAHGAP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=354, Percent_Identity=47.4576271186441, Blast_Score=334, Evalue=7e-93,
Organism=Escherichia coli, GI1789929, Length=388, Percent_Identity=28.3505154639175, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1786668, Length=371, Percent_Identity=29.3800539083558, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1789665, Length=377, Percent_Identity=29.7082228116711, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI87081951, Length=119, Percent_Identity=35.2941176470588, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87081796, Length=333, Percent_Identity=24.3243243243243, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 44486; Mature: 44354

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTDTPIPVPQPPSRRRWLFLFSLICLALAGTYMLVSRDPDANDGTKKTPPSPPVAVVTQ
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCHHEEEH
AAKKSDISVYLTGIGTVTPLNTVTVRSRVDGQLMEVLYREGQTVSRGQLLARIDPRPFQV
HCCCCCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCEEEEECCCCEEE
LLTQAEGQMARDQAQLSNARVDLQRYRTLWAQNSIPRQQLDTQEALVRQYQAAVKSDQGQ
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHCCCCC
VDSARLQLTYSRITAPCDGRVGLRLVDAGNIVHASDSGGLVVITRMQPMTVVFTIPEDNL
CCCEEEEEEEHHCCCCCCCCCCEEEEECCCEEEECCCCCEEEEEECCCEEEEEEECCCCC
PLLVDRMRGGRKLAVDAFDREQKRVLATGSLLTLDNQIDPGTGTVKLKAIFTNRDNELFP
CCCEECCCCCEEEEEECCCCCCCEEEECCCEEEECCCCCCCCCEEEEEEEEECCCCCCCC
NQFVNARLLVDVRRDAITVPSAAIQNGPKGTFVYLVKGNRTVELRPVEKGESEGGKTAIT
CHHCCEEEEEEECCCEEECCHHHHCCCCCCEEEEEEECCEEEEEEECCCCCCCCCCHHHH
RGLAIGEQVVVDGAERLREGSRVQIKQPGQASATPVRRDTNPAHGAP
HHHHCCCHHEECCHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
STDTPIPVPQPPSRRRWLFLFSLICLALAGTYMLVSRDPDANDGTKKTPPSPPVAVVTQ
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCHHEEEH
AAKKSDISVYLTGIGTVTPLNTVTVRSRVDGQLMEVLYREGQTVSRGQLLARIDPRPFQV
HCCCCCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCEEEEECCCCEEE
LLTQAEGQMARDQAQLSNARVDLQRYRTLWAQNSIPRQQLDTQEALVRQYQAAVKSDQGQ
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHCCCCC
VDSARLQLTYSRITAPCDGRVGLRLVDAGNIVHASDSGGLVVITRMQPMTVVFTIPEDNL
CCCEEEEEEEHHCCCCCCCCCCEEEEECCCEEEECCCCCEEEEEECCCEEEEEEECCCCC
PLLVDRMRGGRKLAVDAFDREQKRVLATGSLLTLDNQIDPGTGTVKLKAIFTNRDNELFP
CCCEECCCCCEEEEEECCCCCCCEEEECCCEEEECCCCCCCCCEEEEEEEEECCCCCCCC
NQFVNARLLVDVRRDAITVPSAAIQNGPKGTFVYLVKGNRTVELRPVEKGESEGGKTAIT
CHHCCEEEEEEECCCEEECCHHHHCCCCCCEEEEEEECCEEEEEEECCCCCCCCCCHHHH
RGLAIGEQVVVDGAERLREGSRVQIKQPGQASATPVRRDTNPAHGAP
HHHHCCCHHEECCHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA