Click here to switch to the map view.

The map label for this gene is recD [H]

Identifier: 118580566

GI number: 118580566

Start: 2311875

End: 2313689

Strand: Direct

Name: recD [H]

Synonym: Ppro_2150

Alternate gene names: 118580566

Gene position: 2311875-2313689 (Clockwise)

Preceding gene: 118580565

Following gene: 118580568

Centisome position: 57.68

GC content: 60.94

Gene sequence:

>1815_bases
ATGGCGACGGTTTTCGAACTCACTGCTACGGACATCCACTTTGCCGAATTCATCCAGCGCGAGGCGGGAGAGACTCCAGC
CTGGTTCAGACCCATGGCTGCGCTGGTGAGCAATGCCATGGGCAACGGCAACATCTGCCTTGATCTGTCGGATATCGCGG
AAAAGATCATCCAGGTGGATGGCAGGGATCAACAGTTCCCGGCACTCTCTGAAATGCGTGACCTACTGGCTGGCATGCCG
GTGATAGGCTCCCCCGGTGATTTTCGGCCACTGGTGCTTGACGGTGATTGCCGGCTCTACCTCTACCGCTACTGGAAGTA
TGAGCGGGAACTGGTGCGGGTCATCCAGGACAAGTCTTCCCTCCCCGGGTGCGACATCGATGAGACGCTCCTTGGCGCGG
GGATCGGCAGGCTTTTCCCCCCCTCTTCCGGAGAGGGGGTCGACTGGCAAAAGGTTGCCGCTCTGGGGGCACTCTGGAAG
CGGTTCTTCGTCATTTCCGGCGGGCCGGGAACGGGCAAGACCTCCACGGTGGTCAAGATCCTTGCACTGCTCCTGGAGCA
GGCGCAAGGGGCAACCGTTCACATTGCCCTGGCTGCTCCGACGGGTAAATCGGCGGCGCGACTCAAGGAATCGATCCGCC
TGATGAAGGAAAGCCTGGATTGCAGCCCGGAGGTGAAGAGCCGGATTCCGGAAGAGGTCACAACCATCCACCGTCTGCTT
GGGGTCCGTTCCGGATCGGTCCGTTTTCAATACTCCGCTGAAAATCAGCTGCCCTACGGCGTTGTCATCGTTGACGAGGC
ATCCATGGTTGCGCTCCCCCTTATGGCAAAGCTGGCCACGGCACTCAAGCCGGAGGCGCGCATCATCCTGCTGGGGGACA
AGGACCAGTTGGCCTCGGTCGAGGCAGGGGCGGCGCTGGGGGACATCTGCGGCGGAGGGCGGCCCGAGCTTTTTTCCACA
GCTTTTCAGTCCTTTGTCGCCAGGGTCGCCGGCGGGCGACTCCCCTCGACAGCTGTGGCCACCTGCACCGGCTTTCCCGG
CGATGCCCTGGCCGTTCTGAAAAGGAATTACCGCTTTGCGACCGAAAGCGGCATTGGGGGGACGGCGAGAGCGGTTAACT
CGGGAGATGCGGGAAGCGCCCTGCGGCTGCTCAACGATGAGCTGCATCAGGATATCCGCTGGCAGGAGGCGCCTTCGACC
GAACAGCTGAAGAAAGCGCTCGCGGAGAGAATCGTCTCCGGGTATTCATCCTACCTCGCGGCCGCTACCGCCGAAGAGGC
ACTGCGGCTGTTCGACGGTTTCAGGGTGCTGACGGCCCTGCGTCAGGGGCCGTACGGCGTTGCCGGGGTCAACGGGCTGA
TCGAGGAGATTCTCGCCGAACAGGGGCTGATCGAGCGTCAAACCCTTTGGTATCCCGGGCGTCCGGTGATGATCACGGTG
AATGATTACCATCTGAAACTGTTCAATGGAGACATCGGGATCGTTTTTCCCGACCCGGAGGCAAATGGGAATCCCAAGGT
CTTCTTCCCCTCTCCGGAAGGGGGGGTGCGCACAGTTTCTCCCTTACGCCTCCCCGCGCACGACACCGTTTACGCCATGA
CCATTCACAAGAGCCAGGGCTCGGAGTTCAACCGGATCCTTTTGCTGCTCCCGGAGCAGGACTCGGAACTTTTGACCAGG
GAATTGATCTATACCGGACTTACCCGGGCAAAAAAAGAGGTTGAGATCTGGGGAGACGAGGGGGTTTTCAGGACCGCCGT
ATCACGGAGGGTCGAGCGCACCTCCGGTCTCAGGAAAGCGCTCTGGGGCGATTGA

Upstream 100 bases:

>100_bases
CAGGGAGAGGGGCGAAGCGTTCGGCGTGTTCCGGGATACTCCGCCAGCGGGATTGATACATGAAGTGACCAATTGCCTGA
TCCAGGCTGGAGGGTAAGAC

Downstream 100 bases:

>100_bases
ACGACTGCCCAGCCCGCATCTGGCAGCGGATGACCATGCTTCTGCATCGTTCCCCATCATGTCGCGCATGTTTGCCGCAA
CTGTCCATGATGTAAAGGCA

Product: exodeoxyribonuclease V subunit alpha

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 604; Mature: 603

Protein sequence:

>604_residues
MATVFELTATDIHFAEFIQREAGETPAWFRPMAALVSNAMGNGNICLDLSDIAEKIIQVDGRDQQFPALSEMRDLLAGMP
VIGSPGDFRPLVLDGDCRLYLYRYWKYERELVRVIQDKSSLPGCDIDETLLGAGIGRLFPPSSGEGVDWQKVAALGALWK
RFFVISGGPGTGKTSTVVKILALLLEQAQGATVHIALAAPTGKSAARLKESIRLMKESLDCSPEVKSRIPEEVTTIHRLL
GVRSGSVRFQYSAENQLPYGVVIVDEASMVALPLMAKLATALKPEARIILLGDKDQLASVEAGAALGDICGGGRPELFST
AFQSFVARVAGGRLPSTAVATCTGFPGDALAVLKRNYRFATESGIGGTARAVNSGDAGSALRLLNDELHQDIRWQEAPST
EQLKKALAERIVSGYSSYLAAATAEEALRLFDGFRVLTALRQGPYGVAGVNGLIEEILAEQGLIERQTLWYPGRPVMITV
NDYHLKLFNGDIGIVFPDPEANGNPKVFFPSPEGGVRTVSPLRLPAHDTVYAMTIHKSQGSEFNRILLLLPEQDSELLTR
ELIYTGLTRAKKEVEIWGDEGVFRTAVSRRVERTSGLRKALWGD

Sequences:

>Translated_604_residues
MATVFELTATDIHFAEFIQREAGETPAWFRPMAALVSNAMGNGNICLDLSDIAEKIIQVDGRDQQFPALSEMRDLLAGMP
VIGSPGDFRPLVLDGDCRLYLYRYWKYERELVRVIQDKSSLPGCDIDETLLGAGIGRLFPPSSGEGVDWQKVAALGALWK
RFFVISGGPGTGKTSTVVKILALLLEQAQGATVHIALAAPTGKSAARLKESIRLMKESLDCSPEVKSRIPEEVTTIHRLL
GVRSGSVRFQYSAENQLPYGVVIVDEASMVALPLMAKLATALKPEARIILLGDKDQLASVEAGAALGDICGGGRPELFST
AFQSFVARVAGGRLPSTAVATCTGFPGDALAVLKRNYRFATESGIGGTARAVNSGDAGSALRLLNDELHQDIRWQEAPST
EQLKKALAERIVSGYSSYLAAATAEEALRLFDGFRVLTALRQGPYGVAGVNGLIEEILAEQGLIERQTLWYPGRPVMITV
NDYHLKLFNGDIGIVFPDPEANGNPKVFFPSPEGGVRTVSPLRLPAHDTVYAMTIHKSQGSEFNRILLLLPEQDSELLTR
ELIYTGLTRAKKEVEIWGDEGVFRTAVSRRVERTSGLRKALWGD
>Mature_603_residues
ATVFELTATDIHFAEFIQREAGETPAWFRPMAALVSNAMGNGNICLDLSDIAEKIIQVDGRDQQFPALSEMRDLLAGMPV
IGSPGDFRPLVLDGDCRLYLYRYWKYERELVRVIQDKSSLPGCDIDETLLGAGIGRLFPPSSGEGVDWQKVAALGALWKR
FFVISGGPGTGKTSTVVKILALLLEQAQGATVHIALAAPTGKSAARLKESIRLMKESLDCSPEVKSRIPEEVTTIHRLLG
VRSGSVRFQYSAENQLPYGVVIVDEASMVALPLMAKLATALKPEARIILLGDKDQLASVEAGAALGDICGGGRPELFSTA
FQSFVARVAGGRLPSTAVATCTGFPGDALAVLKRNYRFATESGIGGTARAVNSGDAGSALRLLNDELHQDIRWQEAPSTE
QLKKALAERIVSGYSSYLAAATAEEALRLFDGFRVLTALRQGPYGVAGVNGLIEEILAEQGLIERQTLWYPGRPVMITVN
DYHLKLFNGDIGIVFPDPEANGNPKVFFPSPEGGVRTVSPLRLPAHDTVYAMTIHKSQGSEFNRILLLLPEQDSELLTRE
LIYTGLTRAKKEVEIWGDEGVFRTAVSRRVERTSGLRKALWGD

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=610, Percent_Identity=41.6393442622951, Blast_Score=394, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 65572; Mature: 65441

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVFELTATDIHFAEFIQREAGETPAWFRPMAALVSNAMGNGNICLDLSDIAEKIIQVD
CCEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCC
GRDQQFPALSEMRDLLAGMPVIGSPGDFRPLVLDGDCRLYLYRYWKYERELVRVIQDKSS
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHCCC
LPGCDIDETLLGAGIGRLFPPSSGEGVDWQKVAALGALWKRFFVISGGPGTGKTSTVVKI
CCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHH
LALLLEQAQGATVHIALAAPTGKSAARLKESIRLMKESLDCSPEVKSRIPEEVTTIHRLL
HHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHH
GVRSGSVRFQYSAENQLPYGVVIVDEASMVALPLMAKLATALKPEARIILLGDKDQLASV
CCCCCCEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHH
EAGAALGDICGGGRPELFSTAFQSFVARVAGGRLPSTAVATCTGFPGDALAVLKRNYRFA
HCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHCCCEE
TESGIGGTARAVNSGDAGSALRLLNDELHQDIRWQEAPSTEQLKKALAERIVSGYSSYLA
ECCCCCCCCEECCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AATAEEALRLFDGFRVLTALRQGPYGVAGVNGLIEEILAEQGLIERQTLWYPGRPVMITV
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEE
NDYHLKLFNGDIGIVFPDPEANGNPKVFFPSPEGGVRTVSPLRLPAHDTVYAMTIHKSQG
EEEEEEEEECCEEEEECCCCCCCCCEEEECCCCCCCEECCCCCCCCCCEEEEEEEECCCC
SEFNRILLLLPEQDSELLTRELIYTGLTRAKKEVEIWGDEGVFRTAVSRRVERTSGLRKA
CCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHH
LWGD
HCCC
>Mature Secondary Structure 
ATVFELTATDIHFAEFIQREAGETPAWFRPMAALVSNAMGNGNICLDLSDIAEKIIQVD
CEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCC
GRDQQFPALSEMRDLLAGMPVIGSPGDFRPLVLDGDCRLYLYRYWKYERELVRVIQDKSS
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHCCC
LPGCDIDETLLGAGIGRLFPPSSGEGVDWQKVAALGALWKRFFVISGGPGTGKTSTVVKI
CCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHH
LALLLEQAQGATVHIALAAPTGKSAARLKESIRLMKESLDCSPEVKSRIPEEVTTIHRLL
HHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHH
GVRSGSVRFQYSAENQLPYGVVIVDEASMVALPLMAKLATALKPEARIILLGDKDQLASV
CCCCCCEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHH
EAGAALGDICGGGRPELFSTAFQSFVARVAGGRLPSTAVATCTGFPGDALAVLKRNYRFA
HCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHCCCEE
TESGIGGTARAVNSGDAGSALRLLNDELHQDIRWQEAPSTEQLKKALAERIVSGYSSYLA
ECCCCCCCCEECCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AATAEEALRLFDGFRVLTALRQGPYGVAGVNGLIEEILAEQGLIERQTLWYPGRPVMITV
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEE
NDYHLKLFNGDIGIVFPDPEANGNPKVFFPSPEGGVRTVSPLRLPAHDTVYAMTIHKSQG
EEEEEEEEECCEEEEECCCCCCCCCEEEECCCCCCCEECCCCCCCCCCEEEEEEEECCCC
SEFNRILLLLPEQDSELLTRELIYTGLTRAKKEVEIWGDEGVFRTAVSRRVERTSGLRKA
CCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHH
LWGD
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]