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The map label for this gene is adcA [H]

Identifier: 118580555

GI number: 118580555

Start: 2295072

End: 2296073

Strand: Reverse

Name: adcA [H]

Synonym: Ppro_2139

Alternate gene names: 118580555

Gene position: 2296073-2295072 (Counterclockwise)

Preceding gene: 118580556

Following gene: 118580554

Centisome position: 57.29

GC content: 64.17

Gene sequence:

>1002_bases
ATGACCCATGACAGCATACACCAGGAGAACGTCACCTGCTCTTTTCGCCGGGCGCTGGCAGCGCTCTGCCTTGCCCTGAT
CGCTCTCTTGGCGGCCTGCGGCGGTACGGACGGACCCCGGACTACTCCCCCCGCGGATGGCAGGTTGCGGGTGGTAACCA
CGCTCTTCCCGCTGTACGACTTTGCCCGTTCCATCGCCGGAGAGCGTGCCCAGGTGTCCATGCTGCTGCCTCCCGGCATG
GAGCCGCACAGCTTCGAACCCCGGCCTGATGACATGCTGCGCATAAACAGTGCCGGCCTGTTCGTCTACACCAATCCGGT
TATGGAGCCCTGGGCAGCCAGGATCATCCAGGGAGTGGACCCGAACCGGGTGCGGGTGATAAACGCGGGCCAGGGTGCAG
GCTATCGGACGGTCACCCCTGATGGCGATGCTGATGGCCATGAACATGGTCACCAGCATGCCGGCGCCCTGGATCCCCAT
ATCTGGCTCGACCTGGACAACGCCCAGCTGATGGTGGACAACATCCTGTCCGGCTTCACGGCCGCCGATCCGGTTAATGC
TGCCTACTACCGCGGCAATGCTTCCGCTCTGAAGTCGAGGCTGGCTGACCTGGACAGGCGCTATCGCGGGGGACTGGCAT
CCTGCGAACGTCGCGAGTTTTTGCATGGCGGCCACTACGCCTTCGGGTATCTGGCCCGACGCTACAACCTGGCCTACCGC
TCCTTAAGCGGCGTCTCGTCGGAATCGGAGCCGTCGGCCGCACGCATGGCCGCCATGGTGCGCCACATCAGGGAGTCCGG
CGCCCAGTACCTGTTCGCCGAGGAGTTGCTCTCACCCCGCCTGACGGAAACCCTGGCTGCCGAGGCAGGGGTGCGGGTGC
TCAGGCTGCACGGGGGGCATAATCTGGCGCTGGACGATTTTCGGGCCGGGGTGACCTTCATCAGCCTGATGGATCGGAAT
CTGGTCAATCTGCAAAAGGGGCTGGCATGCAGGCCGAAGTAG

Upstream 100 bases:

>100_bases
GATGGAATGCTTGATGAGGTCGCGCAACGCTCCGGGGTGCGCGTAACCTCCCCCATCCTGCGGATCAACGGCCTCTGCGC
GGCCAGTCGGGAGAATCAGC

Downstream 100 bases:

>100_bases
TCAGGACGGAGCGCCTGGGCTGCTCCTACTACAGCGGTCCGGTGCTGGAGAACGTCTCCATCTCGGTGCAGGCCGGCGAC
TATGTGGGCATCGTGGGGCC

Product: periplasmic solute binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MTHDSIHQENVTCSFRRALAALCLALIALLAACGGTDGPRTTPPADGRLRVVTTLFPLYDFARSIAGERAQVSMLLPPGM
EPHSFEPRPDDMLRINSAGLFVYTNPVMEPWAARIIQGVDPNRVRVINAGQGAGYRTVTPDGDADGHEHGHQHAGALDPH
IWLDLDNAQLMVDNILSGFTAADPVNAAYYRGNASALKSRLADLDRRYRGGLASCERREFLHGGHYAFGYLARRYNLAYR
SLSGVSSESEPSAARMAAMVRHIRESGAQYLFAEELLSPRLTETLAAEAGVRVLRLHGGHNLALDDFRAGVTFISLMDRN
LVNLQKGLACRPK

Sequences:

>Translated_333_residues
MTHDSIHQENVTCSFRRALAALCLALIALLAACGGTDGPRTTPPADGRLRVVTTLFPLYDFARSIAGERAQVSMLLPPGM
EPHSFEPRPDDMLRINSAGLFVYTNPVMEPWAARIIQGVDPNRVRVINAGQGAGYRTVTPDGDADGHEHGHQHAGALDPH
IWLDLDNAQLMVDNILSGFTAADPVNAAYYRGNASALKSRLADLDRRYRGGLASCERREFLHGGHYAFGYLARRYNLAYR
SLSGVSSESEPSAARMAAMVRHIRESGAQYLFAEELLSPRLTETLAAEAGVRVLRLHGGHNLALDDFRAGVTFISLMDRN
LVNLQKGLACRPK
>Mature_332_residues
THDSIHQENVTCSFRRALAALCLALIALLAACGGTDGPRTTPPADGRLRVVTTLFPLYDFARSIAGERAQVSMLLPPGME
PHSFEPRPDDMLRINSAGLFVYTNPVMEPWAARIIQGVDPNRVRVINAGQGAGYRTVTPDGDADGHEHGHQHAGALDPHI
WLDLDNAQLMVDNILSGFTAADPVNAAYYRGNASALKSRLADLDRRYRGGLASCERREFLHGGHYAFGYLARRYNLAYRS
LSGVSSESEPSAARMAAMVRHIRESGAQYLFAEELLSPRLTETLAAEAGVRVLRLHGGHNLALDDFRAGVTFISLMDRNL
VNLQKGLACRPK

Specific function: Part of the high-affinity ABC transporter complex AdcABC involved in zinc import (Probable) [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=257, Percent_Identity=24.5136186770428, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 36385; Mature: 36254

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHDSIHQENVTCSFRRALAALCLALIALLAACGGTDGPRTTPPADGRLRVVTTLFPLYD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHH
FARSIAGERAQVSMLLPPGMEPHSFEPRPDDMLRINSAGLFVYTNPVMEPWAARIIQGVD
HHHHHCCCCEEEEEECCCCCCCCCCCCCCCCEEEEECCEEEEEECCCCCHHHHHHHCCCC
PNRVRVINAGQGAGYRTVTPDGDADGHEHGHQHAGALDPHIWLDLDNAQLMVDNILSGFT
CCEEEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCC
AADPVNAAYYRGNASALKSRLADLDRRYRGGLASCERREFLHGGHYAFGYLARRYNLAYR
CCCCCCHHEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
SLSGVSSESEPSAARMAAMVRHIRESGAQYLFAEELLSPRLTETLAAEAGVRVLRLHGGH
HHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHCCCEEEEEECCC
NLALDDFRAGVTFISLMDRNLVNLQKGLACRPK
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
THDSIHQENVTCSFRRALAALCLALIALLAACGGTDGPRTTPPADGRLRVVTTLFPLYD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHH
FARSIAGERAQVSMLLPPGMEPHSFEPRPDDMLRINSAGLFVYTNPVMEPWAARIIQGVD
HHHHHCCCCEEEEEECCCCCCCCCCCCCCCCEEEEECCEEEEEECCCCCHHHHHHHCCCC
PNRVRVINAGQGAGYRTVTPDGDADGHEHGHQHAGALDPHIWLDLDNAQLMVDNILSGFT
CCEEEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCC
AADPVNAAYYRGNASALKSRLADLDRRYRGGLASCERREFLHGGHYAFGYLARRYNLAYR
CCCCCCHHEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
SLSGVSSESEPSAARMAAMVRHIRESGAQYLFAEELLSPRLTETLAAEAGVRVLRLHGGH
HHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHCCCEEEEEECCC
NLALDDFRAGVTFISLMDRNLVNLQKGLACRPK
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9811636 [H]