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The map label for this gene is atoS [H]

Identifier: 118580505

GI number: 118580505

Start: 2247177

End: 2249585

Strand: Reverse

Name: atoS [H]

Synonym: Ppro_2089

Alternate gene names: 118580505

Gene position: 2249585-2247177 (Counterclockwise)

Preceding gene: 118580507

Following gene: 118580501

Centisome position: 56.13

GC content: 62.35

Gene sequence:

>2409_bases
ATGACCTATACGATTAGCGAACTCATCGATATCGATGAACTCCGGTCGCTGTGTGAACTATTCACGCGCATGACCGGCTT
CGTAACCGCCATTCTCGACATGGAGGGGAATATCCTCATTGCCACCGGCTGGCAGGATATCTGCACCCGCTTTCACCGCG
CCACCCCCGCTTCCGCCGCCCGCTGCCGGGAGAGTGACGTCTATCTGGCCGGGAAGTTGCTACAGGGGGAAACCTACACC
CTGTATGCGTGCAGAAACGGTCTGGTGGATGTGGCGGTACCCATCGTGGTGGCGGGGATGCAGGTGGGCAAGCTGTACTC
GGGGCAGTTCCTGTTTGCGCCGCCCGATACGGATTTTTTCCGGCGCCAGGGGGCTGAATTCGGTTTCGACGAGGCTTCCT
ATCTGGAGGCGCTGGCCAGGGTTCCGGTTGTCAGCGAGGAGCGGGTGCGCCTGGTCATGGAGTTTCTCTGCCGTCTGGCC
GAGATGATCGGCAGGATGGGGCTGGCCAGCAAAAATGCCCGCCAGGCCAGTCTGGTGGTGGAAAATAGCCCGGTGACGCT
CTTTCGCTGGAAGGCGGCCGCGGGATGGCCGGTGGAGTTCGTTTCTGAGAATGTGGTCCAGTTCGGGTATGCGCCGGAAG
AACTCCTGTCCGGGAATGTTTCCTTTGCCAGTCTGATCCACCCCGCCGACCTGGAGCGGGTGGTGGCCGAGGTGGGCGGG
AACGGCGAGGATGTTTCCGATACGCTTTCCCAGGAGTACCGTCTCGTCACCAAAAGCGGTGAGGTGCGCTGGGTTGATGA
CCGCACCACGGTGGAGCGTGACGGAGAGGGGAGGATCACCCATTACCAGGGTATCGCCATGGATATCACCGAACGGAGGC
ATGCCGCCGATGAACTTGCCATGGAAAAGGAACGCCTGGCAGTGACGTTGCGTTCCATCGGTGACGGGGTGATCACCGCC
GATATGGAGGGTAGGGTGATCCTGCTCAACAAGGTGGCCGAGGAACTGACCGGCTGGAAGCAGGAAGAGGCGCGGGGAAA
GGCGTTTGATGAGGTCTTCCGCATCATCGATGAGAGAACGCGCCAGCAGCGCTCCAGTCCGGTGGCCCATGTGCTGAAGA
ACGGTAGCGGTTCCGAGCTTGCCCACAACACCGTACTGGTGGCCAGGGACGGCCGGGAGCGGTTGATCGCCGACAGCGTG
GCGCCGATCCGGGACCGGGAGAGTCGGTTGGTGGGGGTGGTGCTGGTGTTCCGCGACATCACCGAAAAGAAGAGGATCGA
GCAGGAGCTGTTCAATGCCCACCGGCTGGAATCCATCGGCGTCCTGGCCGGCGGCATCGCCCACGACTTCAACAACCTGC
TGACCGCCATCCTGGGAAATATCTCTCTGGCCAAGATGCTCGTCTCCGAGGGGGACAGGATGTTCAGGAACCTGGATGAA
GCGGAGAAGGCCTCCCTGCGGGCCAAGGGGCTGACCCAGCAGCTTTTGACCTTCTCCCGCGGCGGCGCGCCGGTGCGCAG
GACCCTGTCTCTGGCCGCCATCATCAGGGAATCGGCGGCCTTCACCCTGTCCGGTTCCGGAACAACCTGCCGTTTTATTC
TGCCCGAAGATCTCTGGCCGGTGGAGGCGGACGAAGGGCAGATCAGTCAGGTGATCAACAATCTGGTGCTTAACGCCGAT
CAGGCCATGCCAGGCGGGGGGGAGGTCGAGATCAGCTGCGCCAATGTGGTCATTGACGCGAAATCGCAACTTCCGTTGCC
GGCCGGCGCCCATGTGCGCATCGCGGTCAGCGACCGGGGCCAGGGCATCCCCCAGGAAGCCATTACCCGTATCTTCGACC
CCTACTTCACCACCAAGCGGAACGGCACAGGACTCGGCCTGGCAACGGTCTATTCCATCATCAGGAACCATGACGGCCAC
ATAGCCGCGACCTCACGCCAGGGTGGAGGCTCAACCTTCACCATCCATCTTCCCGCCCTGGTGGAGGGGGAGGTGCCGGT
GGCGCCCGAGGAGACGGTGGTAGATTCGGGAAGGGGGACGGTGCTGGTCATGGATGACGAGGAGAGTATCCGGGAGATCG
CCGGAGAGATGCTCTCCTATCTGGGATACGACGCGACCGTTGCCTGTGACGGCGCCGAAGCGGTGGAGCTGTACCGCCAG
GCGCGGGAAAGGGGGCAGCCATTTAGCGTCGTGCTCATGGATCTCACCATTCCGGGCGGCATGGGGGGGAGGGAGGCCAT
CACCCGTCTGCGCCAGATGGACGAATCGGTGCTGGCGGTGGTCTCCAGCGGCTACTCCACCGATCCGATCATGGCCGACT
ACCGTGCCTATGGCTTTAGCGGCGTGATCATCAAGCCGTACCGGGTGGCGGAGCTGAAAAGCGTGCTGGATCAACTTCTG
GCCAGCTGA

Upstream 100 bases:

>100_bases
GTACTACGAGAGAGAGTCTTGCTTTGGCCGTAGCCGCGGGGTAGAGTGTGCACTCTGTTTCTGGCTTGTTTCCAGCACAC
TTTTTGCGGTGGAGATACGG

Downstream 100 bases:

>100_bases
GCTCCATGCCCTCAGGCCGCGGCCGATTTCGGTTTCACCATCCCCGTGTGTAGCCCTCACAGCAGTCAAGGCAGAGCCTG
CGCCCCTCCTTAAGCCGGAT

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 802; Mature: 801

Protein sequence:

>802_residues
MTYTISELIDIDELRSLCELFTRMTGFVTAILDMEGNILIATGWQDICTRFHRATPASAARCRESDVYLAGKLLQGETYT
LYACRNGLVDVAVPIVVAGMQVGKLYSGQFLFAPPDTDFFRRQGAEFGFDEASYLEALARVPVVSEERVRLVMEFLCRLA
EMIGRMGLASKNARQASLVVENSPVTLFRWKAAAGWPVEFVSENVVQFGYAPEELLSGNVSFASLIHPADLERVVAEVGG
NGEDVSDTLSQEYRLVTKSGEVRWVDDRTTVERDGEGRITHYQGIAMDITERRHAADELAMEKERLAVTLRSIGDGVITA
DMEGRVILLNKVAEELTGWKQEEARGKAFDEVFRIIDERTRQQRSSPVAHVLKNGSGSELAHNTVLVARDGRERLIADSV
APIRDRESRLVGVVLVFRDITEKKRIEQELFNAHRLESIGVLAGGIAHDFNNLLTAILGNISLAKMLVSEGDRMFRNLDE
AEKASLRAKGLTQQLLTFSRGGAPVRRTLSLAAIIRESAAFTLSGSGTTCRFILPEDLWPVEADEGQISQVINNLVLNAD
QAMPGGGEVEISCANVVIDAKSQLPLPAGAHVRIAVSDRGQGIPQEAITRIFDPYFTTKRNGTGLGLATVYSIIRNHDGH
IAATSRQGGGSTFTIHLPALVEGEVPVAPEETVVDSGRGTVLVMDDEESIREIAGEMLSYLGYDATVACDGAEAVELYRQ
ARERGQPFSVVLMDLTIPGGMGGREAITRLRQMDESVLAVVSSGYSTDPIMADYRAYGFSGVIIKPYRVAELKSVLDQLL
AS

Sequences:

>Translated_802_residues
MTYTISELIDIDELRSLCELFTRMTGFVTAILDMEGNILIATGWQDICTRFHRATPASAARCRESDVYLAGKLLQGETYT
LYACRNGLVDVAVPIVVAGMQVGKLYSGQFLFAPPDTDFFRRQGAEFGFDEASYLEALARVPVVSEERVRLVMEFLCRLA
EMIGRMGLASKNARQASLVVENSPVTLFRWKAAAGWPVEFVSENVVQFGYAPEELLSGNVSFASLIHPADLERVVAEVGG
NGEDVSDTLSQEYRLVTKSGEVRWVDDRTTVERDGEGRITHYQGIAMDITERRHAADELAMEKERLAVTLRSIGDGVITA
DMEGRVILLNKVAEELTGWKQEEARGKAFDEVFRIIDERTRQQRSSPVAHVLKNGSGSELAHNTVLVARDGRERLIADSV
APIRDRESRLVGVVLVFRDITEKKRIEQELFNAHRLESIGVLAGGIAHDFNNLLTAILGNISLAKMLVSEGDRMFRNLDE
AEKASLRAKGLTQQLLTFSRGGAPVRRTLSLAAIIRESAAFTLSGSGTTCRFILPEDLWPVEADEGQISQVINNLVLNAD
QAMPGGGEVEISCANVVIDAKSQLPLPAGAHVRIAVSDRGQGIPQEAITRIFDPYFTTKRNGTGLGLATVYSIIRNHDGH
IAATSRQGGGSTFTIHLPALVEGEVPVAPEETVVDSGRGTVLVMDDEESIREIAGEMLSYLGYDATVACDGAEAVELYRQ
ARERGQPFSVVLMDLTIPGGMGGREAITRLRQMDESVLAVVSSGYSTDPIMADYRAYGFSGVIIKPYRVAELKSVLDQLL
AS
>Mature_801_residues
TYTISELIDIDELRSLCELFTRMTGFVTAILDMEGNILIATGWQDICTRFHRATPASAARCRESDVYLAGKLLQGETYTL
YACRNGLVDVAVPIVVAGMQVGKLYSGQFLFAPPDTDFFRRQGAEFGFDEASYLEALARVPVVSEERVRLVMEFLCRLAE
MIGRMGLASKNARQASLVVENSPVTLFRWKAAAGWPVEFVSENVVQFGYAPEELLSGNVSFASLIHPADLERVVAEVGGN
GEDVSDTLSQEYRLVTKSGEVRWVDDRTTVERDGEGRITHYQGIAMDITERRHAADELAMEKERLAVTLRSIGDGVITAD
MEGRVILLNKVAEELTGWKQEEARGKAFDEVFRIIDERTRQQRSSPVAHVLKNGSGSELAHNTVLVARDGRERLIADSVA
PIRDRESRLVGVVLVFRDITEKKRIEQELFNAHRLESIGVLAGGIAHDFNNLLTAILGNISLAKMLVSEGDRMFRNLDEA
EKASLRAKGLTQQLLTFSRGGAPVRRTLSLAAIIRESAAFTLSGSGTTCRFILPEDLWPVEADEGQISQVINNLVLNADQ
AMPGGGEVEISCANVVIDAKSQLPLPAGAHVRIAVSDRGQGIPQEAITRIFDPYFTTKRNGTGLGLATVYSIIRNHDGHI
AATSRQGGGSTFTIHLPALVEGEVPVAPEETVVDSGRGTVLVMDDEESIREIAGEMLSYLGYDATVACDGAEAVELYRQA
RERGQPFSVVLMDLTIPGGMGGREAITRLRQMDESVLAVVSSGYSTDPIMADYRAYGFSGVIIKPYRVAELKSVLDQLLA
S

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=363, Percent_Identity=31.404958677686, Blast_Score=157, Evalue=3e-39,
Organism=Escherichia coli, GI1790436, Length=278, Percent_Identity=29.8561151079137, Blast_Score=115, Evalue=9e-27,
Organism=Escherichia coli, GI48994928, Length=451, Percent_Identity=27.2727272727273, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1788381, Length=182, Percent_Identity=31.8681318681319, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1788713, Length=284, Percent_Identity=26.7605633802817, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1786600, Length=359, Percent_Identity=24.5125348189415, Blast_Score=80, Evalue=7e-16,
Organism=Escherichia coli, GI145693157, Length=272, Percent_Identity=27.5735294117647, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081816, Length=265, Percent_Identity=29.0566037735849, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786912, Length=241, Percent_Identity=27.8008298755187, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790300, Length=356, Percent_Identity=25, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 87710; Mature: 87579

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYTISELIDIDELRSLCELFTRMTGFVTAILDMEGNILIATGWQDICTRFHRATPASAA
CCEEHHHHHCHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEECHHHHHHHHHCCCCCHHH
RCRESDVYLAGKLLQGETYTLYACRNGLVDVAVPIVVAGMQVGKLYSGQFLFAPPDTDFF
HCCCCCEEEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHCCEECCCEEECCCCCHHH
RRQGAEFGFDEASYLEALARVPVVSEERVRLVMEFLCRLAEMIGRMGLASKNARQASLVV
HHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
ENSPVTLFRWKAAAGWPVEFVSENVVQFGYAPEELLSGNVSFASLIHPADLERVVAEVGG
ECCCEEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHCCCCCHHHHCCHHHHHHHHHHHCC
NGEDVSDTLSQEYRLVTKSGEVRWVDDRTTVERDGEGRITHYQGIAMDITERRHAADELA
CCCCHHHHHHHHEEEEECCCCEEEECCCCCCCCCCCCCEEEECCEEEEHHHHHHHHHHHH
MEKERLAVTLRSIGDGVITADMEGRVILLNKVAEELTGWKQEEARGKAFDEVFRIIDERT
HHHHHHHHHHHHCCCCEEEECCCCCEEEHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHH
RQQRSSPVAHVLKNGSGSELAHNTVLVARDGRERLIADSVAPIRDRESRLVGVVLVFRDI
HHHHCCCHHHHHCCCCCCCEECCEEEEEECCCHHHHHHCCCCCCCCCCHHEEHHHHHHHH
TEKKRIEQELFNAHRLESIGVLAGGIAHDFNNLLTAILGNISLAKMLVSEGDRMFRNLDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHCCCH
AEKASLRAKGLTQQLLTFSRGGAPVRRTLSLAAIIRESAAFTLSGSGTTCRFILPEDLWP
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCC
VEADEGQISQVINNLVLNADQAMPGGGEVEISCANVVIDAKSQLPLPAGAHVRIAVSDRG
CCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCEEEEEECCCC
QGIPQEAITRIFDPYFTTKRNGTGLGLATVYSIIRNHDGHIAATSRQGGGSTFTIHLPAL
CCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEECEE
VEGEVPVAPEETVVDSGRGTVLVMDDEESIREIAGEMLSYLGYDATVACDGAEAVELYRQ
ECCCCCCCCCHHHEECCCCEEEEECCHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHH
ARERGQPFSVVLMDLTIPGGMGGREAITRLRQMDESVLAVVSSGYSTDPIMADYRAYGFS
HHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCC
GVIIKPYRVAELKSVLDQLLAS
CEEECCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TYTISELIDIDELRSLCELFTRMTGFVTAILDMEGNILIATGWQDICTRFHRATPASAA
CEEHHHHHCHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEECHHHHHHHHHCCCCCHHH
RCRESDVYLAGKLLQGETYTLYACRNGLVDVAVPIVVAGMQVGKLYSGQFLFAPPDTDFF
HCCCCCEEEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHCCEECCCEEECCCCCHHH
RRQGAEFGFDEASYLEALARVPVVSEERVRLVMEFLCRLAEMIGRMGLASKNARQASLVV
HHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
ENSPVTLFRWKAAAGWPVEFVSENVVQFGYAPEELLSGNVSFASLIHPADLERVVAEVGG
ECCCEEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHCCCCCHHHHCCHHHHHHHHHHHCC
NGEDVSDTLSQEYRLVTKSGEVRWVDDRTTVERDGEGRITHYQGIAMDITERRHAADELA
CCCCHHHHHHHHEEEEECCCCEEEECCCCCCCCCCCCCEEEECCEEEEHHHHHHHHHHHH
MEKERLAVTLRSIGDGVITADMEGRVILLNKVAEELTGWKQEEARGKAFDEVFRIIDERT
HHHHHHHHHHHHCCCCEEEECCCCCEEEHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHH
RQQRSSPVAHVLKNGSGSELAHNTVLVARDGRERLIADSVAPIRDRESRLVGVVLVFRDI
HHHHCCCHHHHHCCCCCCCEECCEEEEEECCCHHHHHHCCCCCCCCCCHHEEHHHHHHHH
TEKKRIEQELFNAHRLESIGVLAGGIAHDFNNLLTAILGNISLAKMLVSEGDRMFRNLDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHCCCH
AEKASLRAKGLTQQLLTFSRGGAPVRRTLSLAAIIRESAAFTLSGSGTTCRFILPEDLWP
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCC
VEADEGQISQVINNLVLNADQAMPGGGEVEISCANVVIDAKSQLPLPAGAHVRIAVSDRG
CCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCEEEEEECCCC
QGIPQEAITRIFDPYFTTKRNGTGLGLATVYSIIRNHDGHIAATSRQGGGSTFTIHLPAL
CCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEECEE
VEGEVPVAPEETVVDSGRGTVLVMDDEESIREIAGEMLSYLGYDATVACDGAEAVELYRQ
ECCCCCCCCCHHHEECCCCEEEEECCHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHH
ARERGQPFSVVLMDLTIPGGMGGREAITRLRQMDESVLAVVSSGYSTDPIMADYRAYGFS
HHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCC
GVIIKPYRVAELKSVLDQLLAS
CEEECCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]