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The map label for this gene is ccdA [H]

Identifier: 118580421

GI number: 118580421

Start: 2153953

End: 2154684

Strand: Reverse

Name: ccdA [H]

Synonym: Ppro_2005

Alternate gene names: 118580421

Gene position: 2154684-2153953 (Counterclockwise)

Preceding gene: 118580422

Following gene: 118580420

Centisome position: 53.76

GC content: 61.07

Gene sequence:

>732_bases
ATGATCCATACCCAGGACGTAACCTATGCCGGCGCGTTCGTCGCCGGCCTGCTCTCCTTTCTCTCCCCCTGCGTCCTGCC
ACTGATTCCCTCGTACATCACCTACATCACCGGACTCTCCTTCGCCGATCTCCAGGAGCAGCATCCCTCGCACCTGGTGC
GCAGAAAAACCTTTCTTCACTCCATCTGCTTCATCATAGGCTTTACCGCGGTATTCGTCCTCCTGGGCGCCTCGGCCACC
ATGATCGGTTCCCTGCTGCAGCAGCATGCCGCCGCCATCCGGAAGATCGGCGGCCTGCTGATCTTCCTTTTCGGTGCCCA
TGTCACCGGTCTGGTGCCGCTCAGGCTGCTGCTGGGGGAGAAACGCATCAGCGTGCGCAACAAGCCCGCAGGCTACGCGG
GGAGCTTCCTGGTCGGCCTGGTGTTCGCCGCCGGCTGGACCCCCTGCATCGGCCCGATCCTGGCATCCATCCTGATGGTT
GCGGCCAACGAGGCGAGGGTTGCCCAGGGGATCATCCTGCTCTTGCTCTACTCCCTGGGGCTGGGCATCCCGTTTCTGCT
CTCTTCCCTGGCGCTGCACCAGTTCCTCTCCCTCTTCAACCGCTTCAAGCGTTTCATCCGTCTGTTTGAAATCATAACCG
GAGTCTTTCTCATGCTGATCGGAATCCTGCTCTTCTCCAACTGGCTCTCGCGCCTGTCCGGCTATGCCTCATACCTGTTC
GGGGGGGTGTAG

Upstream 100 bases:

>100_bases
TCGTCGTCAAAAAGATCATCGGTCCCCTTGCCTGGGATGCTCCCGATACAATTGCCTTTCTTGAGGACCTGATGAAGAAG
TAGGGGGGTGTGCGCTGACC

Downstream 100 bases:

>100_bases
ATGAACGTGCATCGCTCCCGTCATTCCATCCAGTTCTCCGTGGCTGACCTGGCGGTAACCGAGGCGTTCTACGCCGGAAT
CCTGGAACTCCCGGTGCAGC

Product: cytochrome c biogenesis protein, transmembrane region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MIHTQDVTYAGAFVAGLLSFLSPCVLPLIPSYITYITGLSFADLQEQHPSHLVRRKTFLHSICFIIGFTAVFVLLGASAT
MIGSLLQQHAAAIRKIGGLLIFLFGAHVTGLVPLRLLLGEKRISVRNKPAGYAGSFLVGLVFAAGWTPCIGPILASILMV
AANEARVAQGIILLLLYSLGLGIPFLLSSLALHQFLSLFNRFKRFIRLFEIITGVFLMLIGILLFSNWLSRLSGYASYLF
GGV

Sequences:

>Translated_243_residues
MIHTQDVTYAGAFVAGLLSFLSPCVLPLIPSYITYITGLSFADLQEQHPSHLVRRKTFLHSICFIIGFTAVFVLLGASAT
MIGSLLQQHAAAIRKIGGLLIFLFGAHVTGLVPLRLLLGEKRISVRNKPAGYAGSFLVGLVFAAGWTPCIGPILASILMV
AANEARVAQGIILLLLYSLGLGIPFLLSSLALHQFLSLFNRFKRFIRLFEIITGVFLMLIGILLFSNWLSRLSGYASYLF
GGV
>Mature_243_residues
MIHTQDVTYAGAFVAGLLSFLSPCVLPLIPSYITYITGLSFADLQEQHPSHLVRRKTFLHSICFIIGFTAVFVLLGASAT
MIGSLLQQHAAAIRKIGGLLIFLFGAHVTGLVPLRLLLGEKRISVRNKPAGYAGSFLVGLVFAAGWTPCIGPILASILMV
AANEARVAQGIILLLLYSLGLGIPFLLSSLALHQFLSLFNRFKRFIRLFEIITGVFLMLIGILLFSNWLSRLSGYASYLF
GGV

Specific function: Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation [H]

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: NA

Molecular weight: Translated: 26384; Mature: 26384

Theoretical pI: Translated: 10.38; Mature: 10.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCC
>Mature Secondary Structure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CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969507; 9068642; 9384377; 10781554; 11844773 [H]