Click here to switch to the map view.

The map label for this gene is perR [H]

Identifier: 118580383

GI number: 118580383

Start: 2110817

End: 2111266

Strand: Reverse

Name: perR [H]

Synonym: Ppro_1966

Alternate gene names: 118580383

Gene position: 2111266-2110817 (Counterclockwise)

Preceding gene: 118580392

Following gene: 118580382

Centisome position: 52.68

GC content: 60.67

Gene sequence:

>450_bases
ATGACACCACTCTCCAACAGCATAGATCACCTGACCCAGACTTTCCGCGAGTCAGGTTTGCGTGTTACCCATCAGCGGCT
TGAGATTTACCGGGAGCTGATGGAGGCCAGGGATCATCCTACAGCTGAACAACTGTATCGCAGGCTGCGCGGGCGAATCC
CGACCCTCTCGCTGGATACGGTCTACCGGACCCTGACGACTCTGGTCACCCATGGCATGGTCAAGCGCCTGGAGACGGTG
GAGAGTCAGGCGCGTTTCGACACGACCCGGCAGCGCCACCATCATATCATCTGCAAGCGCTGCAACGAAATCATGGACTT
CCACTGGCCGCTGCTGGATGAGACGCCGCTGCCGGGAGAGGTGGATTCGTGGGGCAGGCTCGACGGAGTCAACGTGGTCG
TGTACGGCGTCTGCGCCCGCTGTCTTGCAGGAGACGCCCAACCGACCTGA

Upstream 100 bases:

>100_bases
ACTGTTTACGCTTCACGGCGATGATCAAAAATGGCAGCTTGACAAATATTCTTTATCTGTTATTTTTACTAAATAAGAAT
AATTACTAAAAGCGGCTGCC

Downstream 100 bases:

>100_bases
TTGTAGAATGGACTATTTGTTTGCCGCCTTGAGTGCGGCTTACCCCCGAGAGGGGGCATACCACCAAACAACCATAGAGG
AGGACTCACCAGATGCCGAG

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 148

Protein sequence:

>149_residues
MTPLSNSIDHLTQTFRESGLRVTHQRLEIYRELMEARDHPTAEQLYRRLRGRIPTLSLDTVYRTLTTLVTHGMVKRLETV
ESQARFDTTRQRHHHIICKRCNEIMDFHWPLLDETPLPGEVDSWGRLDGVNVVVYGVCARCLAGDAQPT

Sequences:

>Translated_149_residues
MTPLSNSIDHLTQTFRESGLRVTHQRLEIYRELMEARDHPTAEQLYRRLRGRIPTLSLDTVYRTLTTLVTHGMVKRLETV
ESQARFDTTRQRHHHIICKRCNEIMDFHWPLLDETPLPGEVDSWGRLDGVNVVVYGVCARCLAGDAQPT
>Mature_148_residues
TPLSNSIDHLTQTFRESGLRVTHQRLEIYRELMEARDHPTAEQLYRRLRGRIPTLSLDTVYRTLTTLVTHGMVKRLETVE
SQARFDTTRQRHHHIICKRCNEIMDFHWPLLDETPLPGEVDSWGRLDGVNVVVYGVCARCLAGDAQPT

Specific function: Manganese-dependent repressor that controls a regulon of oxidative stress resistance and iron-storage proteins. May act as a hydrogen peroxide and organic hydroperoxide sensor [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=128, Percent_Identity=32.03125, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17265; Mature: 17134

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPLSNSIDHLTQTFRESGLRVTHQRLEIYRELMEARDHPTAEQLYRRLRGRIPTLSLDT
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHH
VYRTLTTLVTHGMVKRLETVESQARFDTTRQRHHHIICKRCNEIMDFHWPLLDETPLPGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
VDSWGRLDGVNVVVYGVCARCLAGDAQPT
CCCCCCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TPLSNSIDHLTQTFRESGLRVTHQRLEIYRELMEARDHPTAEQLYRRLRGRIPTLSLDT
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHH
VYRTLTTLVTHGMVKRLETVESQARFDTTRQRHHHIICKRCNEIMDFHWPLLDETPLPGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
VDSWGRLDGVNVVVYGVCARCLAGDAQPT
CCCCCCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA