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The map label for this gene is arsB [H]

Identifier: 118580351

GI number: 118580351

Start: 2083392

End: 2084366

Strand: Direct

Name: arsB [H]

Synonym: Ppro_1934

Alternate gene names: 118580351

Gene position: 2083392-2084366 (Clockwise)

Preceding gene: 118580350

Following gene: 118580356

Centisome position: 51.98

GC content: 58.26

Gene sequence:

>975_bases
ATGTGGAAGTTACTGACTTTTCTTCAGAAAAACCTGATATGGACGATACCCGCGGCCATGGTGGCGGGGCTTGCGTACGG
TTCGCTGTGGAACGCTTCCCCCCTGAAGTCGACCATCGTGCCGCTGACATTCCTCATGGTCTATCCCATGATGGTCAACC
TGCAACTGGAAAAGGTCTTTTCAACCGAGGGGATTCGCTGCCAGTTGGCGACCATGCTGATCAATTTCGGGGTTATTCCC
TTCGTGGCTTTTTTCATCGGCCGGTGGTTCTTCGCGGACCAGCCTCTGATCATGCTCGGCCTGCTGCTGGCGGCCCTGCT
CCCCACCAGCGGCATGACCATCACCTGGACCGGTTTCGCCGGCGGTGATATCAACGCGGCCATCAAGATGACCGTCATCG
GCCTGGTTGCCGGCTCCATCGCCACCCCCTTCTATGCCCTCTGGCTCATGGGAGCGGCGATTGAAATACCGCTGGCCGAA
GTCTTCCGGCAGATACTGTTCATCGTTTTCGTTCCCATGCTGCTCGGGTATGCCACAAAACGGATGCTGATCAAACGTTA
CGGCCGGGAAGCCTACCAGCGCGACCTGCAGAAGAAATTTCCCCTCTTTTCCACTCTGGGCGTACTGGGGATCGTCTTTG
TCGCCATGGCGTTGAAATCAGGGAGCATTATGGGCAATCCCGCCATGCTCCTTTCCTACCTCGGGCCGCTCGCCCTGCTC
TATCTGGTGAATTTCCTGTTGAGCACCCTGGTGGGCAAGCTGTTCTTCCCCCGCCCCGAAGCCATCGCCCTGGTGTACGG
CACCGTCATGCGCAACCTGTCCATCGCCCTTGCCATCGCCATTACGGTTTTCAGGGAAAAGGGAGCGGAAATCGCCATCA
TCATCGCCCTGGCCTATATCGTCCAGGTGCAGGCGGCGGCCTGGTACGTCAAGTTTACCGACCGCATCTTCGGCAAGCGC
GCGGCAACGGCCTGA

Upstream 100 bases:

>100_bases
CCCGAACAAAAAAACAGTTGAAAAACCTCAATACATATAATATTCATATATTCATATGATTTATTATTTTCAGAATCATC
ACAACCAACAGGGAGGCATT

Downstream 100 bases:

>100_bases
GACGGCGCGGTATCAGGGCCGGCACCCCGTACCGTCTCTCTTTTCGCGCGGTTCGCGTCAGGCGGTAGCGTGCCGTCACA
CAAAGCCGTCCCCATGAGCG

Product: bile acid:sodium symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MWKLLTFLQKNLIWTIPAAMVAGLAYGSLWNASPLKSTIVPLTFLMVYPMMVNLQLEKVFSTEGIRCQLATMLINFGVIP
FVAFFIGRWFFADQPLIMLGLLLAALLPTSGMTITWTGFAGGDINAAIKMTVIGLVAGSIATPFYALWLMGAAIEIPLAE
VFRQILFIVFVPMLLGYATKRMLIKRYGREAYQRDLQKKFPLFSTLGVLGIVFVAMALKSGSIMGNPAMLLSYLGPLALL
YLVNFLLSTLVGKLFFPRPEAIALVYGTVMRNLSIALAIAITVFREKGAEIAIIIALAYIVQVQAAAWYVKFTDRIFGKR
AATA

Sequences:

>Translated_324_residues
MWKLLTFLQKNLIWTIPAAMVAGLAYGSLWNASPLKSTIVPLTFLMVYPMMVNLQLEKVFSTEGIRCQLATMLINFGVIP
FVAFFIGRWFFADQPLIMLGLLLAALLPTSGMTITWTGFAGGDINAAIKMTVIGLVAGSIATPFYALWLMGAAIEIPLAE
VFRQILFIVFVPMLLGYATKRMLIKRYGREAYQRDLQKKFPLFSTLGVLGIVFVAMALKSGSIMGNPAMLLSYLGPLALL
YLVNFLLSTLVGKLFFPRPEAIALVYGTVMRNLSIALAIAITVFREKGAEIAIIIALAYIVQVQAAAWYVKFTDRIFGKR
AATA
>Mature_324_residues
MWKLLTFLQKNLIWTIPAAMVAGLAYGSLWNASPLKSTIVPLTFLMVYPMMVNLQLEKVFSTEGIRCQLATMLINFGVIP
FVAFFIGRWFFADQPLIMLGLLLAALLPTSGMTITWTGFAGGDINAAIKMTVIGLVAGSIATPFYALWLMGAAIEIPLAE
VFRQILFIVFVPMLLGYATKRMLIKRYGREAYQRDLQKKFPLFSTLGVLGIVFVAMALKSGSIMGNPAMLLSYLGPLALL
YLVNFLLSTLVGKLFFPRPEAIALVYGTVMRNLSIALAIAITVFREKGAEIAIIIALAYIVQVQAAAWYVKFTDRIFGKR
AATA

Specific function: Seems to confer resistance to arsenite by allowing cells to extrude this compound. Could be part of an arsenite extrusion pump [H]

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 35674; Mature: 35674

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWKLLTFLQKNLIWTIPAAMVAGLAYGSLWNASPLKSTIVPLTFLMVYPMMVNLQLEKVF
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
STEGIRCQLATMLINFGVIPFVAFFIGRWFFADQPLIMLGLLLAALLPTSGMTITWTGFA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCC
GGDINAAIKMTVIGLVAGSIATPFYALWLMGAAIEIPLAEVFRQILFIVFVPMLLGYATK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
RMLIKRYGREAYQRDLQKKFPLFSTLGVLGIVFVAMALKSGSIMGNPAMLLSYLGPLALL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
YLVNFLLSTLVGKLFFPRPEAIALVYGTVMRNLSIALAIAITVFREKGAEIAIIIALAYI
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
VQVQAAAWYVKFTDRIFGKRAATA
HHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MWKLLTFLQKNLIWTIPAAMVAGLAYGSLWNASPLKSTIVPLTFLMVYPMMVNLQLEKVF
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
STEGIRCQLATMLINFGVIPFVAFFIGRWFFADQPLIMLGLLLAALLPTSGMTITWTGFA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCC
GGDINAAIKMTVIGLVAGSIATPFYALWLMGAAIEIPLAEVFRQILFIVFVPMLLGYATK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
RMLIKRYGREAYQRDLQKKFPLFSTLGVLGIVFVAMALKSGSIMGNPAMLLSYLGPLALL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
YLVNFLLSTLVGKLFFPRPEAIALVYGTVMRNLSIALAIAITVFREKGAEIAIIIALAYI
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
VQVQAAAWYVKFTDRIFGKRAATA
HHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895; 9537360 [H]