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The map label for this gene is katA [H]

Identifier: 118580349

GI number: 118580349

Start: 2081206

End: 2082672

Strand: Direct

Name: katA [H]

Synonym: Ppro_1932

Alternate gene names: 118580349

Gene position: 2081206-2082672 (Clockwise)

Preceding gene: 118580344

Following gene: 118580350

Centisome position: 51.93

GC content: 61.08

Gene sequence:

>1467_bases
ATGATGAGCAAGGATACAAAACTCACCACCAGGAATGGCGCCCCTGTTGTCGACAACCAGAACACCATGACGGCCGGACC
GCGCGGACCTGTGCTGCTGCAGGATGTGTGGTACCTGGAGAAACTGGCCCACTTCGACCGCGAGGTAATCCCGGAGCGGC
GCATGCACGCCAAGGGCTCCGGCGCCTTCGGCACCTTCACCGTCACCCACGACATCACCCAGTACACCAAAGCCAGTATC
TTCTCTGCAATCGGCAAGAAGACCGAGTTGTTCACCCGTTTTTCCACCGTGGCCGGTGAGCGGGGCGCGGCCGATGCCGA
GCGGGATATCCGTGGTTTTGCAACAAAATTTTACACCGAGGAGGGGAACTGGGACCTGGTGGGGAACAACACGCCGGTCT
TCTTCCTGCGCGATCCGCTCAAGTTCCCCGACCTGAACCACGCCGTGAAAAGGGATCCGCGCACCAATATGCGCAGCGCA
AAGAACAACTGGGACTTCTGGACCTCACTTCCCGAGGCGCTGCACCAGGTTACCATCGTCATGAGCGACCGGGGCATCCC
GGCCAGCTACCGCCATATGCACGGCTTCGGCAGCCACACCTTCAGCTTCATCAACGCCAAGAACGAACGTTACTGGGTCA
AGTTCCACCTGCGCACCCAGCAGGGGATCAAGAACCTAAGCGACGAGGAGGCCGAGGCTCTGGTTGGCAAGTGCCGGGAG
AGCCACCAGCGCGACCTGTACGAGAGCATCGAAAAGGGGGATTTTCCCCGCTGGACCATGTTTGTGCAAATCATGCCGGA
AAAGGATGCCGCCACCTACAAATTCCACCCCTTCGACCTGACCAAGGTCTGGCTTAAAAAAGACTACCCGCTGATCGAGG
TGGGGGTGATGGAACTGAACAAAAACCCGGAGAACTACTTCGCCGACGTGGAGCAGGCCGCCTTCAACCCGGCCAACGTG
GTGCCCGGCATCGGCTTCTCACCGGACAAGATGCTCCAGGGCAGGCTCTTCTCCTACGGCGATGCACAGCGCTACCGCCT
GGGGGTCAACCACCACCAGATCCCGGTCAACGCCCCCCGCTGCCCCTACCACAGCTTCCACCGCGACGGTTCCATGCGGG
TGGACGGCAACTACGGCAGCACCCTGGGGTACGAGCCCAATAGCTACGGCGAGTGGCAGCAGCAGCCGGAGTACACCGAG
CCCCCACTTGAGCTGTCGGGGGCGGCGGACAACTGGGACTTCCGCAAGGATGATGACGATTACTACACCCAGCCCGGCCT
GCTTTTCCGCCTGATCGGAGCGGAGAAGCAGAAGCTGCTCTTCGAAAATACCGGACGCGGCATGGGAGACGCGCCGCGGG
AGATCAAGATCCGCCATATCGCCAACTGCTACAAGGCCGACCCTGACTATGGCAAGGGGGTGGCCAACGCCCTGGGCATC
CCCATGTCCGAGGTGCCGACATCCTGA

Upstream 100 bases:

>100_bases
CGCTGGTGAGATTGCGCATTGATTCTCATACGCTACGCTTAGCCGTAAGCCTGAACACGTGGTAGTAGCGCACCGCCACC
ATCCCATGAAAAGGAGAAGC

Downstream 100 bases:

>100_bases
TGGAATACGGTCATATGTCACGACAACGGACGCTTCTCGGAGAGCGTCCGTTGTCGTTCATACCATGCTTCCCGGTAAAT
CAATGACAAAGGAGAATCCC

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MMSKDTKLTTRNGAPVVDNQNTMTAGPRGPVLLQDVWYLEKLAHFDREVIPERRMHAKGSGAFGTFTVTHDITQYTKASI
FSAIGKKTELFTRFSTVAGERGAADAERDIRGFATKFYTEEGNWDLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTNMRSA
KNNWDFWTSLPEALHQVTIVMSDRGIPASYRHMHGFGSHTFSFINAKNERYWVKFHLRTQQGIKNLSDEEAEALVGKCRE
SHQRDLYESIEKGDFPRWTMFVQIMPEKDAATYKFHPFDLTKVWLKKDYPLIEVGVMELNKNPENYFADVEQAAFNPANV
VPGIGFSPDKMLQGRLFSYGDAQRYRLGVNHHQIPVNAPRCPYHSFHRDGSMRVDGNYGSTLGYEPNSYGEWQQQPEYTE
PPLELSGAADNWDFRKDDDDYYTQPGLLFRLIGAEKQKLLFENTGRGMGDAPREIKIRHIANCYKADPDYGKGVANALGI
PMSEVPTS

Sequences:

>Translated_488_residues
MMSKDTKLTTRNGAPVVDNQNTMTAGPRGPVLLQDVWYLEKLAHFDREVIPERRMHAKGSGAFGTFTVTHDITQYTKASI
FSAIGKKTELFTRFSTVAGERGAADAERDIRGFATKFYTEEGNWDLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTNMRSA
KNNWDFWTSLPEALHQVTIVMSDRGIPASYRHMHGFGSHTFSFINAKNERYWVKFHLRTQQGIKNLSDEEAEALVGKCRE
SHQRDLYESIEKGDFPRWTMFVQIMPEKDAATYKFHPFDLTKVWLKKDYPLIEVGVMELNKNPENYFADVEQAAFNPANV
VPGIGFSPDKMLQGRLFSYGDAQRYRLGVNHHQIPVNAPRCPYHSFHRDGSMRVDGNYGSTLGYEPNSYGEWQQQPEYTE
PPLELSGAADNWDFRKDDDDYYTQPGLLFRLIGAEKQKLLFENTGRGMGDAPREIKIRHIANCYKADPDYGKGVANALGI
PMSEVPTS
>Mature_488_residues
MMSKDTKLTTRNGAPVVDNQNTMTAGPRGPVLLQDVWYLEKLAHFDREVIPERRMHAKGSGAFGTFTVTHDITQYTKASI
FSAIGKKTELFTRFSTVAGERGAADAERDIRGFATKFYTEEGNWDLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTNMRSA
KNNWDFWTSLPEALHQVTIVMSDRGIPASYRHMHGFGSHTFSFINAKNERYWVKFHLRTQQGIKNLSDEEAEALVGKCRE
SHQRDLYESIEKGDFPRWTMFVQIMPEKDAATYKFHPFDLTKVWLKKDYPLIEVGVMELNKNPENYFADVEQAAFNPANV
VPGIGFSPDKMLQGRLFSYGDAQRYRLGVNHHQIPVNAPRCPYHSFHRDGSMRVDGNYGSTLGYEPNSYGEWQQQPEYTE
PPLELSGAADNWDFRKDDDDYYTQPGLLFRLIGAEKQKLLFENTGRGMGDAPREIKIRHIANCYKADPDYGKGVANALGI
PMSEVPTS

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=481, Percent_Identity=51.5592515592516, Blast_Score=493, Evalue=1e-139,
Organism=Escherichia coli, GI48994891, Length=499, Percent_Identity=43.0861723446894, Blast_Score=380, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI71998444, Length=469, Percent_Identity=50.1066098081023, Blast_Score=473, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI25151141, Length=473, Percent_Identity=48.6257928118393, Blast_Score=463, Evalue=1e-130,
Organism=Caenorhabditis elegans, GI25147792, Length=473, Percent_Identity=48.6257928118393, Blast_Score=462, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6320462, Length=471, Percent_Identity=48.619957537155, Blast_Score=407, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6321525, Length=517, Percent_Identity=35.7833655705996, Blast_Score=307, Evalue=2e-84,
Organism=Drosophila melanogaster, GI17981717, Length=480, Percent_Identity=48.125, Blast_Score=462, Evalue=1e-130,
Organism=Drosophila melanogaster, GI19920968, Length=475, Percent_Identity=45.0526315789474, Blast_Score=429, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 55647; Mature: 55647

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSKDTKLTTRNGAPVVDNQNTMTAGPRGPVLLQDVWYLEKLAHFDREVIPERRMHAKGS
CCCCCCEEEECCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCC
GAFGTFTVTHDITQYTKASIFSAIGKKTELFTRFSTVAGERGAADAERDIRGFATKFYTE
CCEEEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHEEEC
EGNWDLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTNMRSAKNNWDFWTSLPEALHQVTIV
CCCEEEECCCCCEEEEECCCCCCCCCHHHHCCCCCHHHHCCCCCHHHHHHHHHHHEEEEE
MSDRGIPASYRHMHGFGSHTFSFINAKNERYWVKFHLRTQQGIKNLSDEEAEALVGKCRE
EECCCCCHHHHHHCCCCCCEEEEEECCCCEEEEEEEEECHHHHHCCCHHHHHHHHHHHHH
SHQRDLYESIEKGDFPRWTMFVQIMPEKDAATYKFHPFDLTKVWLKKDYPLIEVGVMELN
HHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEEEECCCCHHHHHHHCCCCEEEEEEEEEC
KNPENYFADVEQAAFNPANVVPGIGFSPDKMLQGRLFSYGDAQRYRLGVNHHQIPVNAPR
CCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCHHHCCCCCCCEEECCCCCCCCCCCCC
CPYHSFHRDGSMRVDGNYGSTLGYEPNSYGEWQQQPEYTEPPLELSGAADNWDFRKDDDD
CCCHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCC
YYTQPGLLFRLIGAEKQKLLFENTGRGMGDAPREIKIRHIANCYKADPDYGKGVANALGI
CCCCCCCEEEECCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCC
PMSEVPTS
CHHHCCCC
>Mature Secondary Structure
MMSKDTKLTTRNGAPVVDNQNTMTAGPRGPVLLQDVWYLEKLAHFDREVIPERRMHAKGS
CCCCCCEEEECCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCC
GAFGTFTVTHDITQYTKASIFSAIGKKTELFTRFSTVAGERGAADAERDIRGFATKFYTE
CCEEEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHEEEC
EGNWDLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTNMRSAKNNWDFWTSLPEALHQVTIV
CCCEEEECCCCCEEEEECCCCCCCCCHHHHCCCCCHHHHCCCCCHHHHHHHHHHHEEEEE
MSDRGIPASYRHMHGFGSHTFSFINAKNERYWVKFHLRTQQGIKNLSDEEAEALVGKCRE
EECCCCCHHHHHHCCCCCCEEEEEECCCCEEEEEEEEECHHHHHCCCHHHHHHHHHHHHH
SHQRDLYESIEKGDFPRWTMFVQIMPEKDAATYKFHPFDLTKVWLKKDYPLIEVGVMELN
HHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEEEECCCCHHHHHHHCCCCEEEEEEEEEC
KNPENYFADVEQAAFNPANVVPGIGFSPDKMLQGRLFSYGDAQRYRLGVNHHQIPVNAPR
CCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCHHHCCCCCCCEEECCCCCCCCCCCCC
CPYHSFHRDGSMRVDGNYGSTLGYEPNSYGEWQQQPEYTEPPLELSGAADNWDFRKDDDD
CCCHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCC
YYTQPGLLFRLIGAEKQKLLFENTGRGMGDAPREIKIRHIANCYKADPDYGKGVANALGI
CCCCCCCEEEECCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCC
PMSEVPTS
CHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA