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The map label for this gene is hupB [H]

Identifier: 118580329

GI number: 118580329

Start: 2061145

End: 2061411

Strand: Direct

Name: hupB [H]

Synonym: Ppro_1912

Alternate gene names: 118580329

Gene position: 2061145-2061411 (Clockwise)

Preceding gene: 118580328

Following gene: 118580339

Centisome position: 51.43

GC content: 50.94

Gene sequence:

>267_bases
ATGACGAAAGCAGAATTCGTAGCAGCAATAGCAGCTGAGCTTGATGTGCCTAAAAATGTTGCGGCAGAGACCGTTGAGGC
GTTCCTGAAGGTCACTACTGACCTACTGAAGGCCGGTGATAAGATTACTTTTCCGGGCTTCGGCACATTCGGTGTTTCAG
AGCGTGCAGCTCGCACTGGTCGCAATCCGCAGACAGGCGCAGAGATTCAGATTGCAGCATCCAAGTCAGGTAAGTTCACG
GCCGGTAAGAATCTCAAGAACCTGTAA

Upstream 100 bases:

>100_bases
ATTACATCAGTTTCTATGGTCGGATTGACCGGAATACGCGACTGACAATCATTCAAAAATGTGATAATTATCCAACCCAA
CACCAATTAAAGGAGAGGCC

Downstream 100 bases:

>100_bases
CCATAAAAAAAGCCAGACCTGTGAGGTTTGGCTTAACTTCGCGCTAACTGTTCTCAAAACATTTTTAAATATTTGGAGAG
AATTGTACTCCCTTCTTGGG

Product: histone family protein DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 88; Mature: 87

Protein sequence:

>88_residues
MTKAEFVAAIAAELDVPKNVAAETVEAFLKVTTDLLKAGDKITFPGFGTFGVSERAARTGRNPQTGAEIQIAASKSGKFT
AGKNLKNL

Sequences:

>Translated_88_residues
MTKAEFVAAIAAELDVPKNVAAETVEAFLKVTTDLLKAGDKITFPGFGTFGVSERAARTGRNPQTGAEIQIAASKSGKFT
AGKNLKNL
>Mature_87_residues
TKAEFVAAIAAELDVPKNVAAETVEAFLKVTTDLLKAGDKITFPGFGTFGVSERAARTGRNPQTGAEIQIAASKSGKFTA
GKNLKNL

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=87, Percent_Identity=51.7241379310345, Blast_Score=87, Evalue=2e-19,
Organism=Escherichia coli, GI1790433, Length=87, Percent_Identity=45.9770114942529, Blast_Score=77, Evalue=2e-16,
Organism=Escherichia coli, GI1787141, Length=88, Percent_Identity=32.9545454545455, Blast_Score=61, Evalue=1e-11,
Organism=Escherichia coli, GI1788005, Length=87, Percent_Identity=35.632183908046, Blast_Score=60, Evalue=4e-11,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9199; Mature: 9067

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKAEFVAAIAAELDVPKNVAAETVEAFLKVTTDLLKAGDKITFPGFGTFGVSERAARTG
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHCC
RNPQTGAEIQIAASKSGKFTAGKNLKNL
CCCCCCCEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
TKAEFVAAIAAELDVPKNVAAETVEAFLKVTTDLLKAGDKITFPGFGTFGVSERAARTG
CHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHCC
RNPQTGAEIQIAASKSGKFTAGKNLKNL
CCCCCCCEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7867950; 10984043; 6793399 [H]