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The map label for this gene is dinB [H]

Identifier: 118580322

GI number: 118580322

Start: 2051262

End: 2052497

Strand: Direct

Name: dinB [H]

Synonym: Ppro_1904

Alternate gene names: 118580322

Gene position: 2051262-2052497 (Clockwise)

Preceding gene: 118580321

Following gene: 118580325

Centisome position: 51.18

GC content: 50.73

Gene sequence:

>1236_bases
ATGGAAGAACAGCGCATTGTGATCCACAACGATATGAATGCGTTTTTTGCTTCGGTCGAGCAACAGGCGAACCCGGAACT
GCGGGGGAAACCAATAGCCGTGGTCGGAGGAGGTGGCAGGACAGTCATCACGACCAGCTCCTATGAAGCACGAGCTTTTG
GCGTCAAGACCGGCATGGCTAAATGGGAGGCACTGAGAGTTTGCCCCCAACTCATCATCGTCGTGGGGGACAATAAGAAA
TACACCTACACATCAGCACGCATCATGGAAATGATGAAGGAATACACCCCACTGGTGGAAGTCTTCTCAATTGATGAAGC
ATGGATGGACATTACCCACTCCCTGTCCATCTTCGGCACCCCGGAACGCATTGCATATTTGTTGAAGGCCCGCATCAAAG
AATCTTTCGGTATCACCTGCTCCATCGGGATCGCCCCCAATAAGCTGCTGGCGAAACTCGCATCTGACCTTCATAAACCG
GATGGATTAACCGTAATCAAACCTGAAGAGGTGTCGCGAGTCCTTGAACGCATGCCGATTAAGGAGCTGTGCGGCATAGG
CAAGAAGACGGAATATCAGTTAAAAGTCATGAATATCAACACCTGTGGCGAGTTGGGACGCTGTGACGAATCACGATTGA
CCCGTAAGTTTGGCATAATCGGTTCAAGGTTGAAGCAGATGGGCCAGGGTATTGACGATAGCCCGGTTACCCCAAACGAA
GAAGATGATGAGGTCAAGAGTGTTGGCCATAGCATGACCTTGAGGAGGGATGTAGAGCGGAGGGAGGATATTCTCAAGTA
CCTGTTGCAGCTATCGGAGATGGTTGGCAGGAGAGCCAGGAGATATGGTGTGTCGGGGAAGACAGTGACTCTGCACGTGC
GATTCGCGGATTTCTACAGCTCGTTCGGCAAACAAAACACCCTGAAATCCTATATCAATCTAAGTGACGACATTTTCAAA
GCGGCGGTCGCTATCCTGGATACGACAGAACTCCCCCAGCCGGTTCGTCAGCTGGGGGTCAAATTGTCCAATTTGAAATA
CCAGGCCGAGCAGTTGTCGTTATTCCGGGATGTGCAGAAGAAGAGTGACGCTATCAAAGCGATGGATGCCGTAAATGATC
GTTACGGTGAGTTTAAGGTGACTTTCGGTTCGTTGCTACAGTCGGAAGACAAGGGGAGTCATGTAATTTCACCGGCATGG
CGACCGGAGGGGATACGAAACGTGGACGTACAATAG

Upstream 100 bases:

>100_bases
CGTGCCCATGCTGATACGGCGTATTCGATCAAGTCGATTATTCATTCAAGGATCAGGCCCAGACCTGGGAGTTGTACCCA
CCCCACAAGACTGAATAGCC

Downstream 100 bases:

>100_bases
GTTAACGCCTTTATATGATTGGCAACTATCACAAAGACTTGGGTATCGAATAGTATTCAACTGATTTACTCGTTAAAATA
AGAACTTAATACAAGTTACC

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MEEQRIVIHNDMNAFFASVEQQANPELRGKPIAVVGGGGRTVITTSSYEARAFGVKTGMAKWEALRVCPQLIIVVGDNKK
YTYTSARIMEMMKEYTPLVEVFSIDEAWMDITHSLSIFGTPERIAYLLKARIKESFGITCSIGIAPNKLLAKLASDLHKP
DGLTVIKPEEVSRVLERMPIKELCGIGKKTEYQLKVMNINTCGELGRCDESRLTRKFGIIGSRLKQMGQGIDDSPVTPNE
EDDEVKSVGHSMTLRRDVERREDILKYLLQLSEMVGRRARRYGVSGKTVTLHVRFADFYSSFGKQNTLKSYINLSDDIFK
AAVAILDTTELPQPVRQLGVKLSNLKYQAEQLSLFRDVQKKSDAIKAMDAVNDRYGEFKVTFGSLLQSEDKGSHVISPAW
RPEGIRNVDVQ

Sequences:

>Translated_411_residues
MEEQRIVIHNDMNAFFASVEQQANPELRGKPIAVVGGGGRTVITTSSYEARAFGVKTGMAKWEALRVCPQLIIVVGDNKK
YTYTSARIMEMMKEYTPLVEVFSIDEAWMDITHSLSIFGTPERIAYLLKARIKESFGITCSIGIAPNKLLAKLASDLHKP
DGLTVIKPEEVSRVLERMPIKELCGIGKKTEYQLKVMNINTCGELGRCDESRLTRKFGIIGSRLKQMGQGIDDSPVTPNE
EDDEVKSVGHSMTLRRDVERREDILKYLLQLSEMVGRRARRYGVSGKTVTLHVRFADFYSSFGKQNTLKSYINLSDDIFK
AAVAILDTTELPQPVRQLGVKLSNLKYQAEQLSLFRDVQKKSDAIKAMDAVNDRYGEFKVTFGSLLQSEDKGSHVISPAW
RPEGIRNVDVQ
>Mature_411_residues
MEEQRIVIHNDMNAFFASVEQQANPELRGKPIAVVGGGGRTVITTSSYEARAFGVKTGMAKWEALRVCPQLIIVVGDNKK
YTYTSARIMEMMKEYTPLVEVFSIDEAWMDITHSLSIFGTPERIAYLLKARIKESFGITCSIGIAPNKLLAKLASDLHKP
DGLTVIKPEEVSRVLERMPIKELCGIGKKTEYQLKVMNINTCGELGRCDESRLTRKFGIIGSRLKQMGQGIDDSPVTPNE
EDDEVKSVGHSMTLRRDVERREDILKYLLQLSEMVGRRARRYGVSGKTVTLHVRFADFYSSFGKQNTLKSYINLSDDIFK
AAVAILDTTELPQPVRQLGVKLSNLKYQAEQLSLFRDVQKKSDAIKAMDAVNDRYGEFKVTFGSLLQSEDKGSHVISPAW
RPEGIRNVDVQ

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=345, Percent_Identity=30.1449275362319, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI7706681, Length=346, Percent_Identity=30.0578034682081, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI154350220, Length=329, Percent_Identity=29.1793313069909, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI7705344, Length=109, Percent_Identity=44.954128440367, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI5729982, Length=125, Percent_Identity=40, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1786425, Length=352, Percent_Identity=34.6590909090909, Blast_Score=188, Evalue=6e-49,
Organism=Escherichia coli, GI1787432, Length=401, Percent_Identity=27.1820448877805, Blast_Score=99, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI193205700, Length=424, Percent_Identity=29.2452830188679, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17537959, Length=242, Percent_Identity=28.5123966942149, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI193205702, Length=357, Percent_Identity=27.1708683473389, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI115534089, Length=123, Percent_Identity=36.5853658536585, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21355641, Length=317, Percent_Identity=32.4921135646688, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24644984, Length=317, Percent_Identity=32.4921135646688, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI19923006, Length=415, Percent_Identity=26.0240963855422, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24668444, Length=124, Percent_Identity=34.6774193548387, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 46150; Mature: 46150

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS50173 UMUC ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEQRIVIHNDMNAFFASVEQQANPELRGKPIAVVGGGGRTVITTSSYEARAFGVKTGMA
CCCCEEEEECCHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHH
KWEALRVCPQLIIVVGDNKKYTYTSARIMEMMKEYTPLVEVFSIDEAWMDITHSLSIFGT
HHHHHHHCCEEEEEEECCCEEEEHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCEEECCC
PERIAYLLKARIKESFGITCSIGIAPNKLLAKLASDLHKPDGLTVIKPEEVSRVLERMPI
HHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHCCH
KELCGIGKKTEYQLKVMNINTCGELGRCDESRLTRKFGIIGSRLKQMGQGIDDSPVTPNE
HHHHCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
EDDEVKSVGHSMTLRRDVERREDILKYLLQLSEMVGRRARRYGVSGKTVTLHVRFADFYS
CHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHH
SFGKQNTLKSYINLSDDIFKAAVAILDTTELPQPVRQLGVKLSNLKYQAEQLSLFRDVQK
HHCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KSDAIKAMDAVNDRYGEFKVTFGSLLQSEDKGSHVISPAWRPEGIRNVDVQ
HHHHHHHHHHHHCCCCCEEEEHHHHHCCCCCCCEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MEEQRIVIHNDMNAFFASVEQQANPELRGKPIAVVGGGGRTVITTSSYEARAFGVKTGMA
CCCCEEEEECCHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHH
KWEALRVCPQLIIVVGDNKKYTYTSARIMEMMKEYTPLVEVFSIDEAWMDITHSLSIFGT
HHHHHHHCCEEEEEEECCCEEEEHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCEEECCC
PERIAYLLKARIKESFGITCSIGIAPNKLLAKLASDLHKPDGLTVIKPEEVSRVLERMPI
HHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHCCH
KELCGIGKKTEYQLKVMNINTCGELGRCDESRLTRKFGIIGSRLKQMGQGIDDSPVTPNE
HHHHCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
EDDEVKSVGHSMTLRRDVERREDILKYLLQLSEMVGRRARRYGVSGKTVTLHVRFADFYS
CHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHH
SFGKQNTLKSYINLSDDIFKAAVAILDTTELPQPVRQLGVKLSNLKYQAEQLSLFRDVQK
HHCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KSDAIKAMDAVNDRYGEFKVTFGSLLQSEDKGSHVISPAWRPEGIRNVDVQ
HHHHHHHHHHHHCCCCCEEEEHHHHHCCCCCCCEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA