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The map label for this gene is aroB [H]

Identifier: 118580199

GI number: 118580199

Start: 1907332

End: 1908267

Strand: Reverse

Name: aroB [H]

Synonym: Ppro_1779

Alternate gene names: 118580199

Gene position: 1908267-1907332 (Counterclockwise)

Preceding gene: 118580200

Following gene: 118580198

Centisome position: 47.61

GC content: 59.83

Gene sequence:

>936_bases
ATGAGCAACAGGGTCGCCGTCATAGATTTTGGCACCAATACCGCGCGGCTTTTGATCGCCGAACGGGTTGAGAAGGGATA
TTTCCGTCATGTCCATCTGCGGCGCGAGATCGTACGCATGGGAGGGAGCTTCAACAAATCGGAAGGGCTGTCGCCCGAGG
CGATGGAGCGCGGTCTTTCCTGCCTGACGCGCTTCTCCGAGCATATCCGTGAGTACGACGTTGTATCGGTACGGGCCGTC
GCCACCAGCGCCGTGCGCGACGCAGGCAACGGGACCGAGTTCGTGGAAAACGTGCGCAGGAAAACCGGTATAGAGCTCGC
GGTCATCGACGGTATTGCCGAGGGGACCCTGACCCTGGCGGGCGTCATGGTGGGACTCGACCGGAGCCACGATGAGATTC
TGGTGGTGGACATCGGCGGCGGCAGCACCGAATATACGTTGGCACGTTCAGAGCGGGCCGCTTTCGTGCGCAGCCTGCCG
CTGGGGGTGGTCAGGCTAACCGAAGGACAGGGGAGCTTGGCAGCCATGGAGAGCAAGATACAGAGGGAGCTGGAGGCGTT
GTGGCGCGACATGGCCGAGTCCCGCTGCCGTATCCGGAACGGTACTCCCCTGGTGGGAACAGCCGGCACCGCAACCACCC
TGGCGGCCATCAGTATGGAGATGGATGAGTACGACTATCGCAAGGTCAACAATACCGTCATCTCCAGGGAAAAGATCGCA
GCCATCTTTGAGCGCCTGCTTCCCCTGACACCACAGGAGAGACTGAAGGTGCCGGGGCTTGAAAAAGGGAGAGAAGATTT
GATTATTTCAGGAATGCTGATCACCTTGCGGACCATGGATCTGTTCGGCATGGGAGAGATGAAGGTCAGCGATTACGGTC
TGCTGGAGGGACTGCTGGTAAGCTTGGACGGAGGAGTCGGACGCTATGGCGAGTGA

Upstream 100 bases:

>100_bases
CGCCACGGACCGCCCTCATGTTTAACGAATTGAACGAGGCCTTTGTGAGAATCGCGGAGCTGAGCTGGAACATCATGGCA
GTACGGGAGCGTAAGAACGG

Downstream 100 bases:

>100_bases
TCTCGCAGAACTGGAGCGGGAGATTGCGTATCGTTTTATCGATCAGGCCCCGCTGCTGCAGGCTCTGACCCATCCGTCGT
TTGAGCATGAGCAGGCCGGG

Product: Ppx/GppA phosphatase

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MSNRVAVIDFGTNTARLLIAERVEKGYFRHVHLRREIVRMGGSFNKSEGLSPEAMERGLSCLTRFSEHIREYDVVSVRAV
ATSAVRDAGNGTEFVENVRRKTGIELAVIDGIAEGTLTLAGVMVGLDRSHDEILVVDIGGGSTEYTLARSERAAFVRSLP
LGVVRLTEGQGSLAAMESKIQRELEALWRDMAESRCRIRNGTPLVGTAGTATTLAAISMEMDEYDYRKVNNTVISREKIA
AIFERLLPLTPQERLKVPGLEKGREDLIISGMLITLRTMDLFGMGEMKVSDYGLLEGLLVSLDGGVGRYGE

Sequences:

>Translated_311_residues
MSNRVAVIDFGTNTARLLIAERVEKGYFRHVHLRREIVRMGGSFNKSEGLSPEAMERGLSCLTRFSEHIREYDVVSVRAV
ATSAVRDAGNGTEFVENVRRKTGIELAVIDGIAEGTLTLAGVMVGLDRSHDEILVVDIGGGSTEYTLARSERAAFVRSLP
LGVVRLTEGQGSLAAMESKIQRELEALWRDMAESRCRIRNGTPLVGTAGTATTLAAISMEMDEYDYRKVNNTVISREKIA
AIFERLLPLTPQERLKVPGLEKGREDLIISGMLITLRTMDLFGMGEMKVSDYGLLEGLLVSLDGGVGRYGE
>Mature_310_residues
SNRVAVIDFGTNTARLLIAERVEKGYFRHVHLRREIVRMGGSFNKSEGLSPEAMERGLSCLTRFSEHIREYDVVSVRAVA
TSAVRDAGNGTEFVENVRRKTGIELAVIDGIAEGTLTLAGVMVGLDRSHDEILVVDIGGGSTEYTLARSERAAFVRSLPL
GVVRLTEGQGSLAAMESKIQRELEALWRDMAESRCRIRNGTPLVGTAGTATTLAAISMEMDEYDYRKVNNTVISREKIAA
IFERLLPLTPQERLKVPGLEKGREDLIISGMLITLRTMDLFGMGEMKVSDYGLLEGLLVSLDGGVGRYGE

Specific function: Degradation Of Inorganic Polyphosphates. Orthophosphate Is Released Progressively From The Ends Of Polyphosphate Of Circa 500 Residues Long, While Chains Of Circa 15 Residues Compete Poorly With Polyphosphate As Substrate. [C]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI1788848, Length=311, Percent_Identity=27.0096463022508, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI48994966, Length=313, Percent_Identity=30.0319488817891, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 34127; Mature: 33996

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNRVAVIDFGTNTARLLIAERVEKGYFRHVHLRREIVRMGGSFNKSEGLSPEAMERGLS
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
CLTRFSEHIREYDVVSVRAVATSAVRDAGNGTEFVENVRRKTGIELAVIDGIAEGTLTLA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHH
GVMVGLDRSHDEILVVDIGGGSTEYTLARSERAAFVRSLPLGVVRLTEGQGSLAAMESKI
HHHHCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHH
QRELEALWRDMAESRCRIRNGTPLVGTAGTATTLAAISMEMDEYDYRKVNNTVISREKIA
HHHHHHHHHHHHHHHHEECCCCCEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AIFERLLPLTPQERLKVPGLEKGREDLIISGMLITLRTMDLFGMGEMKVSDYGLLEGLLV
HHHHHHCCCCCHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCEECCHHHHHHHHE
SLDGGVGRYGE
EECCCCCCCCC
>Mature Secondary Structure 
SNRVAVIDFGTNTARLLIAERVEKGYFRHVHLRREIVRMGGSFNKSEGLSPEAMERGLS
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
CLTRFSEHIREYDVVSVRAVATSAVRDAGNGTEFVENVRRKTGIELAVIDGIAEGTLTLA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHH
GVMVGLDRSHDEILVVDIGGGSTEYTLARSERAAFVRSLPLGVVRLTEGQGSLAAMESKI
HHHHCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHH
QRELEALWRDMAESRCRIRNGTPLVGTAGTATTLAAISMEMDEYDYRKVNNTVISREKIA
HHHHHHHHHHHHHHHHEECCCCCEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AIFERLLPLTPQERLKVPGLEKGREDLIISGMLITLRTMDLFGMGEMKVSDYGLLEGLLV
HHHHHHCCCCCHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCEECCHHHHHHHHE
SLDGGVGRYGE
EECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]