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The map label for this gene is paaK [H]

Identifier: 118580174

GI number: 118580174

Start: 1886449

End: 1887756

Strand: Direct

Name: paaK [H]

Synonym: Ppro_1754

Alternate gene names: 118580174

Gene position: 1886449-1887756 (Clockwise)

Preceding gene: 118580173

Following gene: 118580175

Centisome position: 47.07

GC content: 58.94

Gene sequence:

>1308_bases
ATGCAGATAAGTATTTGGGACCCCCAGCACGAATCCATGCCGCGGGAGGAACTGGAACAGCTTCAACTGGAACGACTCCA
GGCAACGCTCAACAGAGTCTACAAGAACGTCACCTGTTACCGGAACAAGTTCAACCAGTTGGGGATCGTTCCCGAGGATG
TGGCTTCCCTGTCCGACCTGTCCAAGCTTCCCTTTACCACCAAGGAGGATCTACGGGTAAACTACCCCTACGGCATGTTC
GCCGTGCCGCTCAGGGAGGTGGTGCGCATTCACTCATCATCCGGCACCACCGGCAAGCCGACGGTGGTCGGATATACCAA
GAACGACCTGAAGACCTGGTCGAACCTGGTGGCGCGGTTCATGACTTCCGCCGGTGTGACCCACGACGATGTGGTTCAGA
TCGCCTTCGGCTATGGCCTGTTTACCGGCGCCTTCGGTCTGCACTACGGTTCCGAGGCGATCGGAGCGGCCGTGATCCCC
ATGGGGGGCGGCAACACGGAAAAGCAGATCATGATCATGCAGGACTACAAGAGCACGGTCCTGGTCTGTACTCCCAGCTA
TGCCATCACCATCGCCGACCACATGGAGAAGAAGGGGATCGACCCAAAATCGTTGTCCCTCAAGGTCGGGCTCTTTGGCG
GCGAGCCCTGGTCCGAGTCCATGCGCAGAGAGATCGAGTCGCGCCTGATGATCCGTGCCACGGACAACTACGGGCTCTCG
GAGATCATCGGGCCGGGCGTTGGAGGAGAGTGCCTGCATAAATGCGGCATGCACATCTCCGAGGACGCCTTCATCGCCGA
AATTATCGACCCCGACACCTGCGAGGTGCTGCCGCCGGGAAGCGTGGGCGAGTTGGTGCTGACCACCATCAGCAAGGAGG
CGTTTCCCATGATCCGTTACCGGACGCGGGACATCACCTGTCTGGACTATGCTCCCTGCGACTGCGGACGCACTACGGTG
CGGATGAGGAAAACCATGGGGCGTTCGGACGACATGCTGATCATCAAGGGGGTCAACGTCTTTCCGTCCCAGATCGAAGA
GGTGCTGATCTCCATCGAGGGGTGCGAACCCCATTACCAGCTGGTGGTGGATCGTAAGGGAGCACTGGATACCCTGGAAG
TGCGCATCGAAGTCACGGAAAACATCTTCTTCGACGAGATGAAGCAGCAGCGCGCCTTTCTAGAGACGGTGGAGAAGCGC
ATCGACTCCGTGCTCGGTGTTGGTGTTACCGTCAAGCTGGTGGAGCCCAACAGTATCCCGCGCCACGAGGGCAAGTCCGA
CCGGGTCATCGACAGACGAATCATCTGA

Upstream 100 bases:

>100_bases
GATGCTCCTGCTCTCTCCGGACGAAGCCGTGGAGACCATCGTCCGCATGGTCAGGGATGCCGTGACAAGCGCCCAATAAA
GCTACAATTTCGAGGTTGTG

Downstream 100 bases:

>100_bases
GTGAGAGCGATGTCACAGCACAGAGGGCAGCTCCGCATAACCACACTATCTTGAACTTGACATAATATATCTTATGGGCG
ATTATTTTAAAGACATCTCA

Product: phenylacetate--CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MQISIWDPQHESMPREELEQLQLERLQATLNRVYKNVTCYRNKFNQLGIVPEDVASLSDLSKLPFTTKEDLRVNYPYGMF
AVPLREVVRIHSSSGTTGKPTVVGYTKNDLKTWSNLVARFMTSAGVTHDDVVQIAFGYGLFTGAFGLHYGSEAIGAAVIP
MGGGNTEKQIMIMQDYKSTVLVCTPSYAITIADHMEKKGIDPKSLSLKVGLFGGEPWSESMRREIESRLMIRATDNYGLS
EIIGPGVGGECLHKCGMHISEDAFIAEIIDPDTCEVLPPGSVGELVLTTISKEAFPMIRYRTRDITCLDYAPCDCGRTTV
RMRKTMGRSDDMLIIKGVNVFPSQIEEVLISIEGCEPHYQLVVDRKGALDTLEVRIEVTENIFFDEMKQQRAFLETVEKR
IDSVLGVGVTVKLVEPNSIPRHEGKSDRVIDRRII

Sequences:

>Translated_435_residues
MQISIWDPQHESMPREELEQLQLERLQATLNRVYKNVTCYRNKFNQLGIVPEDVASLSDLSKLPFTTKEDLRVNYPYGMF
AVPLREVVRIHSSSGTTGKPTVVGYTKNDLKTWSNLVARFMTSAGVTHDDVVQIAFGYGLFTGAFGLHYGSEAIGAAVIP
MGGGNTEKQIMIMQDYKSTVLVCTPSYAITIADHMEKKGIDPKSLSLKVGLFGGEPWSESMRREIESRLMIRATDNYGLS
EIIGPGVGGECLHKCGMHISEDAFIAEIIDPDTCEVLPPGSVGELVLTTISKEAFPMIRYRTRDITCLDYAPCDCGRTTV
RMRKTMGRSDDMLIIKGVNVFPSQIEEVLISIEGCEPHYQLVVDRKGALDTLEVRIEVTENIFFDEMKQQRAFLETVEKR
IDSVLGVGVTVKLVEPNSIPRHEGKSDRVIDRRII
>Mature_435_residues
MQISIWDPQHESMPREELEQLQLERLQATLNRVYKNVTCYRNKFNQLGIVPEDVASLSDLSKLPFTTKEDLRVNYPYGMF
AVPLREVVRIHSSSGTTGKPTVVGYTKNDLKTWSNLVARFMTSAGVTHDDVVQIAFGYGLFTGAFGLHYGSEAIGAAVIP
MGGGNTEKQIMIMQDYKSTVLVCTPSYAITIADHMEKKGIDPKSLSLKVGLFGGEPWSESMRREIESRLMIRATDNYGLS
EIIGPGVGGECLHKCGMHISEDAFIAEIIDPDTCEVLPPGSVGELVLTTISKEAFPMIRYRTRDITCLDYAPCDCGRTTV
RMRKTMGRSDDMLIIKGVNVFPSQIEEVLISIEGCEPHYQLVVDRKGALDTLEVRIEVTENIFFDEMKQQRAFLETVEKR
IDSVLGVGVTVKLVEPNSIPRHEGKSDRVIDRRII

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=427, Percent_Identity=50.8196721311475, Blast_Score=430, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 48593; Mature: 48593

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQISIWDPQHESMPREELEQLQLERLQATLNRVYKNVTCYRNKFNQLGIVPEDVASLSDL
CEEEEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
SKLPFTTKEDLRVNYPYGMFAVPLREVVRIHSSSGTTGKPTVVGYTKNDLKTWSNLVARF
HHCCCCCCCCCEEECCCCEEHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHH
MTSAGVTHDDVVQIAFGYGLFTGAFGLHYGSEAIGAAVIPMGGGNTEKQIMIMQDYKSTV
HHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCEEEEECCCCCCCCEEEEEECCCCEE
LVCTPSYAITIADHMEKKGIDPKSLSLKVGLFGGEPWSESMRREIESRLMIRATDNYGLS
EEECCCEEEEEHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCEEEEEECCCCHH
EIIGPGVGGECLHKCGMHISEDAFIAEIIDPDTCEVLPPGSVGELVLTTISKEAFPMIRY
HHHCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEE
RTRDITCLDYAPCDCGRTTVRMRKTMGRSDDMLIIKGVNVFPSQIEEVLISIEGCEPHYQ
ECCCEEEEECCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHEEECCCCCCEE
LVVDRKGALDTLEVRIEVTENIFFDEMKQQRAFLETVEKRIDSVLGVGVTVKLVEPNSIP
EEEECCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCC
RHEGKSDRVIDRRII
CCCCCCCCCHHCCCC
>Mature Secondary Structure
MQISIWDPQHESMPREELEQLQLERLQATLNRVYKNVTCYRNKFNQLGIVPEDVASLSDL
CEEEEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
SKLPFTTKEDLRVNYPYGMFAVPLREVVRIHSSSGTTGKPTVVGYTKNDLKTWSNLVARF
HHCCCCCCCCCEEECCCCEEHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHH
MTSAGVTHDDVVQIAFGYGLFTGAFGLHYGSEAIGAAVIPMGGGNTEKQIMIMQDYKSTV
HHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCEEEEECCCCCCCCEEEEEECCCCEE
LVCTPSYAITIADHMEKKGIDPKSLSLKVGLFGGEPWSESMRREIESRLMIRATDNYGLS
EEECCCEEEEEHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCEEEEEECCCCHH
EIIGPGVGGECLHKCGMHISEDAFIAEIIDPDTCEVLPPGSVGELVLTTISKEAFPMIRY
HHHCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEE
RTRDITCLDYAPCDCGRTTVRMRKTMGRSDDMLIIKGVNVFPSQIEEVLISIEGCEPHYQ
ECCCEEEEECCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHEEECCCCCCEE
LVVDRKGALDTLEVRIEVTENIFFDEMKQQRAFLETVEKRIDSVLGVGVTVKLVEPNSIP
EEEECCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCC
RHEGKSDRVIDRRII
CCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]