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The map label for this gene is fabD [H]

Identifier: 118580163

GI number: 118580163

Start: 1875627

End: 1876547

Strand: Direct

Name: fabD [H]

Synonym: Ppro_1743

Alternate gene names: 118580163

Gene position: 1875627-1876547 (Clockwise)

Preceding gene: 118580162

Following gene: 118580164

Centisome position: 46.8

GC content: 58.96

Gene sequence:

>921_bases
ATGAGAAAGACGGCTTTTGTTTTTCCTGGTCAAGGCTCGCAATACCCGGGTATGGGCAAGGAACTGTTCGATACCTACCG
GGTTTCCCGTGAGGTCTTTGAAGAGGCCGATGAAGCCCTCGGACTGAAGCTTTCCACCCTCTGCTTCGAGGGGGGAGAAG
ATGAACTGAAGCTGACCGCCAACACCCAGCCCGCTATCCTGACCACCAGCATCGCCATCCTGAAGGCTCTTCTGCAGGAA
ACCGGCCTTAAACCCGATTACGTTGCCGGCCACTCTCTGGGCGAGTTTTCTGCCTTGGTCTGCACCGGAACCCTGTCCCT
GGCCGATGCGGTGCGCACGGTGCGCTCACGCGGCTTCTTCATGCAGGACGCGGTTCCCGTGGGAACCGGTGCCATGGCGG
CAATCTTGAGCGTCAGTGCCGAAGTGCTGGACGAGATCTGCCAGGAGGCTGCCCAGGGGGAGATCGTCGCTCCCGCCAAC
TTCAACTCGCCCGGACAGGTCGTTATCGCCGGCCATTCCGGTGCTGTCCACCGTGCTATCACCATAGCCAAGGAGCGGGG
GTTCAAGAAGGCGCTCATGCTTCCGGTTAGCGCACCATTCCACTGTGCGCTGATGCAACCGGCGGCTGAAAGGCTTGCCG
AGGTGCTTGAACGGGTAAAGTTCGCCCATGTCAAGGTGCCCTATGTTGCCAATGCTGATGCGGAACCCAATACCAACCGC
ACCAGAATCAAGCCGCTGCTCATAACCCAGGTCTGCGCGCCGGTGCTCTGGGAACAGTCGGTCAGGAAAATGGCGTCTCT
GGGCGTGGAACGATTCGTTGAGATCGGTCCCGGCAAGGTCCTGTCCGGCCTTGTTAAGCGGATCGCCAAGGAGAGCCTGG
TTGACAATGTGGAGAATATTGCCACCCTTAAGGCTCTATAA

Upstream 100 bases:

>100_bases
TGTTTCGCGCTGTCCCGGTTTCTGATCCCCCGGCGGAGCTTTGGCAATTGACTTCAATTGCGCTATAGTGAAGAATCCAC
ATGATTGATGAGGTAATCAC

Downstream 100 bases:

>100_bases
ACCAACAAACATGATTTCTGAAGGAGGAAGGTTATGGTTAAAGACAGGGTTGCCGTTGTAACCGGGGCGTCGCGCGGTAT
CGGACGCAGCATAGCGCTTG

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MRKTAFVFPGQGSQYPGMGKELFDTYRVSREVFEEADEALGLKLSTLCFEGGEDELKLTANTQPAILTTSIAILKALLQE
TGLKPDYVAGHSLGEFSALVCTGTLSLADAVRTVRSRGFFMQDAVPVGTGAMAAILSVSAEVLDEICQEAAQGEIVAPAN
FNSPGQVVIAGHSGAVHRAITIAKERGFKKALMLPVSAPFHCALMQPAAERLAEVLERVKFAHVKVPYVANADAEPNTNR
TRIKPLLITQVCAPVLWEQSVRKMASLGVERFVEIGPGKVLSGLVKRIAKESLVDNVENIATLKAL

Sequences:

>Translated_306_residues
MRKTAFVFPGQGSQYPGMGKELFDTYRVSREVFEEADEALGLKLSTLCFEGGEDELKLTANTQPAILTTSIAILKALLQE
TGLKPDYVAGHSLGEFSALVCTGTLSLADAVRTVRSRGFFMQDAVPVGTGAMAAILSVSAEVLDEICQEAAQGEIVAPAN
FNSPGQVVIAGHSGAVHRAITIAKERGFKKALMLPVSAPFHCALMQPAAERLAEVLERVKFAHVKVPYVANADAEPNTNR
TRIKPLLITQVCAPVLWEQSVRKMASLGVERFVEIGPGKVLSGLVKRIAKESLVDNVENIATLKAL
>Mature_306_residues
MRKTAFVFPGQGSQYPGMGKELFDTYRVSREVFEEADEALGLKLSTLCFEGGEDELKLTANTQPAILTTSIAILKALLQE
TGLKPDYVAGHSLGEFSALVCTGTLSLADAVRTVRSRGFFMQDAVPVGTGAMAAILSVSAEVLDEICQEAAQGEIVAPAN
FNSPGQVVIAGHSGAVHRAITIAKERGFKKALMLPVSAPFHCALMQPAAERLAEVLERVKFAHVKVPYVANADAEPNTNR
TRIKPLLITQVCAPVLWEQSVRKMASLGVERFVEIGPGKVLSGLVKRIAKESLVDNVENIATLKAL

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=301, Percent_Identity=31.5614617940199, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI41872631, Length=299, Percent_Identity=27.4247491638796, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI27477045, Length=112, Percent_Identity=38.3928571428571, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1787334, Length=288, Percent_Identity=52.4305555555556, Blast_Score=280, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI17550940, Length=319, Percent_Identity=29.7805642633229, Blast_Score=117, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71984332, Length=291, Percent_Identity=28.8659793814433, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI212642053, Length=319, Percent_Identity=24.7648902821317, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24665753, Length=303, Percent_Identity=33.3333333333333, Blast_Score=134, Evalue=6e-32,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32788; Mature: 32788

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKTAFVFPGQGSQYPGMGKELFDTYRVSREVFEEADEALGLKLSTLCFEGGEDELKLTA
CCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECCCCCCEEEEC
NTQPAILTTSIAILKALLQETGLKPDYVAGHSLGEFSALVCTGTLSLADAVRTVRSRGFF
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCE
MQDAVPVGTGAMAAILSVSAEVLDEICQEAAQGEIVAPANFNSPGQVVIAGHSGAVHRAI
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCEEEECCCCCHHHHH
TIAKERGFKKALMLPVSAPFHCALMQPAAERLAEVLERVKFAHVKVPYVANADAEPNTNR
HHHHHCCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCEEECCCCCCCCCC
TRIKPLLITQVCAPVLWEQSVRKMASLGVERFVEIGPGKVLSGLVKRIAKESLVDNVENI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ATLKAL
HHHHCC
>Mature Secondary Structure
MRKTAFVFPGQGSQYPGMGKELFDTYRVSREVFEEADEALGLKLSTLCFEGGEDELKLTA
CCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECCCCCCEEEEC
NTQPAILTTSIAILKALLQETGLKPDYVAGHSLGEFSALVCTGTLSLADAVRTVRSRGFF
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCE
MQDAVPVGTGAMAAILSVSAEVLDEICQEAAQGEIVAPANFNSPGQVVIAGHSGAVHRAI
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCEEEECCCCCHHHHH
TIAKERGFKKALMLPVSAPFHCALMQPAAERLAEVLERVKFAHVKVPYVANADAEPNTNR
HHHHHCCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCEEECCCCCCCCCC
TRIKPLLITQVCAPVLWEQSVRKMASLGVERFVEIGPGKVLSGLVKRIAKESLVDNVENI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ATLKAL
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]