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The map label for this gene is asnC

Identifier: 118580126

GI number: 118580126

Start: 1831432

End: 1832811

Strand: Reverse

Name: asnC

Synonym: Ppro_1706

Alternate gene names: 118580126

Gene position: 1832811-1831432 (Counterclockwise)

Preceding gene: 118580129

Following gene: 118580125

Centisome position: 45.73

GC content: 65.8

Gene sequence:

>1380_bases
GTGAGAACAATCATCAGACAGCTGCTGTCCCAGGGGGTAAGCGGACAGACCTACGCCATTGCCGGCTGGGTCCGATCCTT
AAGGATTTCCAAGGGAATCGCCTTCATCGCGCTCAACGACGGCTCCAACCTGGCCGGAATCCAGGTGGTGGTGGAAGAGC
AGAGCCCGGCCTTTTCTGAGATCGACGCCATAGCCACCGGCTGTTCCTTACGGGTCACGGGCACGCTGGTGGCATCACCG
GCCGCCGGCCAGGAGCGGGAACTGCGCGCGGAGAGCATCGCCATCGTGGGTACCAGCGACGAGAACTACCCGCTGCAGAA
GAAGCGGCACTCTTTCGAATACCTGCGGGAGATCGCCCACCTGCGGCCGCGCAGCAACACCTTCGGCGCGGTGTTCAGGC
TGCGCTCCCGCCTGGCCCAGGCCATCCACCGCTTCTTCGGCGACAACAACTTCCTCTACGTGCATACGCCGATCATCACC
GCCAGCGACTGCGAGGGGGCCGGCGAGCTGTTCCGGGTGACCACCCTGGACGCCGCCTCCCCTCCCCTGCTGGAGGGGAG
GCCGGACTTCGGCCAGGACTTCTTCGGCCAGAAGACCGGCCTGACCGTCAGCGGTCAGCTGGAGGGGGAACTGTTCGCCC
TGGCCTTCTCCGACATCTACACCTTCGGCCCCACCTTTAGGGCCGAGAACTCCAACACCCCCCGCCACGCCGCCGAGTTC
TGGATGATCGAGCCGGAGATGGCCTTCGCCGACCTGGCCGACGACGCCGCCCTGGCGGAGAAGTTCGTCCGCTACCTCTG
CCGCTTTGCCCTGGAGGAGTGTGCTGAGGAGATGGCCTTCTTCGACCGCCAGATCGAGAAGGGGCTCCTGGAGCGGGTGC
GCCGGGTAGCCGAGGCGGACTTCGTGCGCATGGAGTACGACGAGGCCATCCAACGGCTGCAGCGGTCGGGCGTCACATTC
TCCTACCCGGTGGAATGGGGGCTGGACCTGCAGACCGAGCACGAACGCTACATCACCGAGAAGATCGTGGGGGGACCGGC
CTTCATCCTCAACTACCCCCGGGACATCAAGGCCTTCTACATGCGCAGCAACCCGGACAACAGGACCGTGGCAGCCATGG
ACCTGCTGGTGCCCAAGGTGGGCGAGATCATCGGCGGTAGCCAGCGCGAGGAGCGGCTGGACGTCCTGGAGGCACGCATG
GCGGAGTTGGGCATCGCCCGGGAGCCGCTCTGGTGGTACCTGGAGAGCCGCCGCTGGGGGAGCTGCCCCCACGCCGGTTT
CGGCCTCGGCTTCGAGCGGTTGGTGATGTACCTGTCCGGCATGGAGAACATCCGCGACGTTATCCCTTTCCCCCGCACTC
CGCGCCACGCCGAGTTCTGA

Upstream 100 bases:

>100_bases
TTTCTAATGATCTTAACATCTCCCCTCCATCCCCCTTGCATCCCCTCCCCCATGCACGTATCATTGCGCCAGCACACGCG
CCGAAGGGAGGATGTAATCC

Downstream 100 bases:

>100_bases
ACCATGTTCATCTTCTGTCTCGAACTCCACCTCTCCCTCTCCTGCGACTCGCTGAAGGGGAAGCGGGGCATCGTCAAGAG
CCTTCTGGGGCGCAGCCGCA

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MRTIIRQLLSQGVSGQTYAIAGWVRSLRISKGIAFIALNDGSNLAGIQVVVEEQSPAFSEIDAIATGCSLRVTGTLVASP
AAGQERELRAESIAIVGTSDENYPLQKKRHSFEYLREIAHLRPRSNTFGAVFRLRSRLAQAIHRFFGDNNFLYVHTPIIT
ASDCEGAGELFRVTTLDAASPPLLEGRPDFGQDFFGQKTGLTVSGQLEGELFALAFSDIYTFGPTFRAENSNTPRHAAEF
WMIEPEMAFADLADDAALAEKFVRYLCRFALEECAEEMAFFDRQIEKGLLERVRRVAEADFVRMEYDEAIQRLQRSGVTF
SYPVEWGLDLQTEHERYITEKIVGGPAFILNYPRDIKAFYMRSNPDNRTVAAMDLLVPKVGEIIGGSQREERLDVLEARM
AELGIAREPLWWYLESRRWGSCPHAGFGLGFERLVMYLSGMENIRDVIPFPRTPRHAEF

Sequences:

>Translated_459_residues
MRTIIRQLLSQGVSGQTYAIAGWVRSLRISKGIAFIALNDGSNLAGIQVVVEEQSPAFSEIDAIATGCSLRVTGTLVASP
AAGQERELRAESIAIVGTSDENYPLQKKRHSFEYLREIAHLRPRSNTFGAVFRLRSRLAQAIHRFFGDNNFLYVHTPIIT
ASDCEGAGELFRVTTLDAASPPLLEGRPDFGQDFFGQKTGLTVSGQLEGELFALAFSDIYTFGPTFRAENSNTPRHAAEF
WMIEPEMAFADLADDAALAEKFVRYLCRFALEECAEEMAFFDRQIEKGLLERVRRVAEADFVRMEYDEAIQRLQRSGVTF
SYPVEWGLDLQTEHERYITEKIVGGPAFILNYPRDIKAFYMRSNPDNRTVAAMDLLVPKVGEIIGGSQREERLDVLEARM
AELGIAREPLWWYLESRRWGSCPHAGFGLGFERLVMYLSGMENIRDVIPFPRTPRHAEF
>Mature_459_residues
MRTIIRQLLSQGVSGQTYAIAGWVRSLRISKGIAFIALNDGSNLAGIQVVVEEQSPAFSEIDAIATGCSLRVTGTLVASP
AAGQERELRAESIAIVGTSDENYPLQKKRHSFEYLREIAHLRPRSNTFGAVFRLRSRLAQAIHRFFGDNNFLYVHTPIIT
ASDCEGAGELFRVTTLDAASPPLLEGRPDFGQDFFGQKTGLTVSGQLEGELFALAFSDIYTFGPTFRAENSNTPRHAAEF
WMIEPEMAFADLADDAALAEKFVRYLCRFALEECAEEMAFFDRQIEKGLLERVRRVAEADFVRMEYDEAIQRLQRSGVTF
SYPVEWGLDLQTEHERYITEKIVGGPAFILNYPRDIKAFYMRSNPDNRTVAAMDLLVPKVGEIIGGSQREERLDVLEARM
AELGIAREPLWWYLESRRWGSCPHAGFGLGFERLVMYLSGMENIRDVIPFPRTPRHAEF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI226491502, Length=455, Percent_Identity=43.2967032967033, Blast_Score=381, Evalue=1e-106,
Organism=Homo sapiens, GI4758762, Length=457, Percent_Identity=28.4463894967177, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI45439306, Length=354, Percent_Identity=29.9435028248588, Blast_Score=130, Evalue=2e-30,
Organism=Escherichia coli, GI1787161, Length=445, Percent_Identity=55.5056179775281, Blast_Score=519, Evalue=1e-148,
Organism=Escherichia coli, GI1788173, Length=105, Percent_Identity=37.1428571428571, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789256, Length=465, Percent_Identity=23.8709677419355, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17556372, Length=430, Percent_Identity=32.7906976744186, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI71984122, Length=449, Percent_Identity=29.1759465478842, Blast_Score=176, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17551876, Length=487, Percent_Identity=24.435318275154, Blast_Score=109, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6319872, Length=462, Percent_Identity=37.8787878787879, Blast_Score=296, Evalue=5e-81,
Organism=Saccharomyces cerevisiae, GI6321807, Length=451, Percent_Identity=28.159645232816, Blast_Score=188, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6323011, Length=343, Percent_Identity=29.4460641399417, Blast_Score=127, Evalue=4e-30,
Organism=Drosophila melanogaster, GI19922416, Length=464, Percent_Identity=35.3448275862069, Blast_Score=270, Evalue=1e-72,
Organism=Drosophila melanogaster, GI19921528, Length=442, Percent_Identity=27.8280542986425, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI17136276, Length=359, Percent_Identity=27.2980501392758, Blast_Score=112, Evalue=5e-25,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SYN_PELPD (A1APP8)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_901376.1
- ProteinModelPortal:   A1APP8
- SMR:   A1APP8
- STRING:   A1APP8
- GeneID:   4572755
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_1706
- eggNOG:   COG0017
- HOGENOM:   HBG745843
- OMA:   EPEMAFC
- PhylomeDB:   A1APP8
- ProtClustDB:   PRK03932
- GO:   GO:0005737
- HAMAP:   MF_00534
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00457

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.22

Molecular weight: Translated: 51733; Mature: 51733

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTIIRQLLSQGVSGQTYAIAGWVRSLRISKGIAFIALNDGSNLAGIQVVVEEQSPAFSE
CHHHHHHHHHCCCCCCEEEHHHHHHHHHHHCCEEEEEECCCCCEEEEEEEEECCCCCHHH
IDAIATGCSLRVTGTLVASPAAGQERELRAESIAIVGTSDENYPLQKKRHSFEYLREIAH
HHHHHCCCEEEEEEEEEECCCCCCHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHH
LRPRSNTFGAVFRLRSRLAQAIHRFFGDNNFLYVHTPIITASDCEGAGELFRVTTLDAAS
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECEEEECCCCCCCCEEEEEEECCCC
PPLLEGRPDFGQDFFGQKTGLTVSGQLEGELFALAFSDIYTFGPTFRAENSNTPRHAAEF
CCCCCCCCCCCHHHCCCCCCEEEEEECCCEEEEEEHHHHHHCCCCEECCCCCCCCHHHHE
WMIEPEMAFADLADDAALAEKFVRYLCRFALEECAEEMAFFDRQIEKGLLERVRRVAEAD
EEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVRMEYDEAIQRLQRSGVTFSYPVEWGLDLQTEHERYITEKIVGGPAFILNYPRDIKAFY
HHHCCHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCEEEE
MRSNPDNRTVAAMDLLVPKVGEIIGGSQREERLDVLEARMAELGIAREPLWWYLESRRWG
EECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHEEEECCCCC
SCPHAGFGLGFERLVMYLSGMENIRDVIPFPRTPRHAEF
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MRTIIRQLLSQGVSGQTYAIAGWVRSLRISKGIAFIALNDGSNLAGIQVVVEEQSPAFSE
CHHHHHHHHHCCCCCCEEEHHHHHHHHHHHCCEEEEEECCCCCEEEEEEEEECCCCCHHH
IDAIATGCSLRVTGTLVASPAAGQERELRAESIAIVGTSDENYPLQKKRHSFEYLREIAH
HHHHHCCCEEEEEEEEEECCCCCCHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHH
LRPRSNTFGAVFRLRSRLAQAIHRFFGDNNFLYVHTPIITASDCEGAGELFRVTTLDAAS
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECEEEECCCCCCCCEEEEEEECCCC
PPLLEGRPDFGQDFFGQKTGLTVSGQLEGELFALAFSDIYTFGPTFRAENSNTPRHAAEF
CCCCCCCCCCCHHHCCCCCCEEEEEECCCEEEEEEHHHHHHCCCCEECCCCCCCCHHHHE
WMIEPEMAFADLADDAALAEKFVRYLCRFALEECAEEMAFFDRQIEKGLLERVRRVAEAD
EEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVRMEYDEAIQRLQRSGVTFSYPVEWGLDLQTEHERYITEKIVGGPAFILNYPRDIKAFY
HHHCCHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCEEEE
MRSNPDNRTVAAMDLLVPKVGEIIGGSQREERLDVLEARMAELGIAREPLWWYLESRRWG
EECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHEEEECCCCC
SCPHAGFGLGFERLVMYLSGMENIRDVIPFPRTPRHAEF
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA