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The map label for this gene is holB [H]

Identifier: 118580086

GI number: 118580086

Start: 1783488

End: 1784471

Strand: Reverse

Name: holB [H]

Synonym: Ppro_1664

Alternate gene names: 118580086

Gene position: 1784471-1783488 (Counterclockwise)

Preceding gene: 118580087

Following gene: 118580085

Centisome position: 44.52

GC content: 64.13

Gene sequence:

>984_bases
ATGCCCTTCTCTGACGTCCTGGGCCATGAGCGGATCGTGGATATCCTGCTCCGCTCGCTCCGCACGGGCAAGACGGCCCA
TGCCTACATCTTCGAGGGCCCGTCGGGCTGCGGCCGGCGGAAGACCGCCCTGGCCCTGGTCCAGGCGCTGTTCTGCGGGG
CCGGCACTAACGATGCCTGCGGTGTCTGCCCCTCCTGCCGCAAGGTGGCGGCCGGAAACCATGCCGATATCCACCTGGTG
AATCCGCTGCCGGACAAGCGCGATATCAGCATCTCCCAGCTGCGCGACGTGCAGCGCGACCTGGCCATGCGCCCCTACGA
GGCACCGCGCGCGGCCTGCATCATCGAACCGGCAGACAGAATGAACACCAGCTCGGCCAATTCGTTTCTGAAGACGCTGG
AAGAACCGCCGGGAAACGCGATCATCATCCTGATCACCGAAAATGCCGACATGCTGCTGCCGACCATCCGTTCGCGCTGC
CAGCTGCTGCGTTTCGCCCCGCTCTCACCGGAACAGATCAGGCTGCTCCTGGAACGCGACGGCATGGACAGCGCCACCGC
CTCGCTGCTGGCGCCTCTGTCCGACGGCAGCATGCAGCGCGCCCTGGAACTGGACAACGACTCACTGGCCCAGCGCCGGG
ACCTGCTGCTCAGGCGCCTCGAGCAGCTCTCCCTGGAGCGGGTCGTAACCATTTTCGAATCATCGGAAGAGTTGAGCGGC
AGTCGGGATGAAACACTGGAGAATCTGGACATGCTGCTCTCCTTCAGCCGTGACATGGTTCACCTGGCAGCAGGATGCAG
CGACATAACCAACCGCACCATCCGGCCGACACTGGAGCGTCTTTCCTGTCGCCTCGATCTCCCGGGGGCGCTGCGACTGG
CCGACAGCATCCTGGATACGCGACGTTCCATCCAGCGCAACGCCAATGCAAAACTGGCCCTGGACCATCTCTTCATGAAC
ATAGCCGCGGCGCTGGCAGCCTGA

Upstream 100 bases:

>100_bases
CCGCAGCGGTTCATCACCGTTGACGGCAGCGGCGGAGTGGAGGAAATCTCCGAGGCCATCGTGGCCCAGGTCCTGCAGAA
CCGGCTCAACAACACCAGTC

Downstream 100 bases:

>100_bases
CGGATGCAGCGCACCGGTTCCGATACCGTCATGACGCAACAGAAACAAGGAGGAAGTCGTTGCCACGCATAGTAACCCTT
CAGTTCAGCACAGCCGGAAA

Product: DNA polymerase III subunit delta'

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MPFSDVLGHERIVDILLRSLRTGKTAHAYIFEGPSGCGRRKTALALVQALFCGAGTNDACGVCPSCRKVAAGNHADIHLV
NPLPDKRDISISQLRDVQRDLAMRPYEAPRAACIIEPADRMNTSSANSFLKTLEEPPGNAIIILITENADMLLPTIRSRC
QLLRFAPLSPEQIRLLLERDGMDSATASLLAPLSDGSMQRALELDNDSLAQRRDLLLRRLEQLSLERVVTIFESSEELSG
SRDETLENLDMLLSFSRDMVHLAAGCSDITNRTIRPTLERLSCRLDLPGALRLADSILDTRRSIQRNANAKLALDHLFMN
IAAALAA

Sequences:

>Translated_327_residues
MPFSDVLGHERIVDILLRSLRTGKTAHAYIFEGPSGCGRRKTALALVQALFCGAGTNDACGVCPSCRKVAAGNHADIHLV
NPLPDKRDISISQLRDVQRDLAMRPYEAPRAACIIEPADRMNTSSANSFLKTLEEPPGNAIIILITENADMLLPTIRSRC
QLLRFAPLSPEQIRLLLERDGMDSATASLLAPLSDGSMQRALELDNDSLAQRRDLLLRRLEQLSLERVVTIFESSEELSG
SRDETLENLDMLLSFSRDMVHLAAGCSDITNRTIRPTLERLSCRLDLPGALRLADSILDTRRSIQRNANAKLALDHLFMN
IAAALAA
>Mature_326_residues
PFSDVLGHERIVDILLRSLRTGKTAHAYIFEGPSGCGRRKTALALVQALFCGAGTNDACGVCPSCRKVAAGNHADIHLVN
PLPDKRDISISQLRDVQRDLAMRPYEAPRAACIIEPADRMNTSSANSFLKTLEEPPGNAIIILITENADMLLPTIRSRCQ
LLRFAPLSPEQIRLLLERDGMDSATASLLAPLSDGSMQRALELDNDSLAQRRDLLLRRLEQLSLERVVTIFESSEELSGS
RDETLENLDMLLSFSRDMVHLAAGCSDITNRTIRPTLERLSCRLDLPGALRLADSILDTRRSIQRNANAKLALDHLFMNI
AAALAA

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786676, Length=215, Percent_Identity=31.6279069767442, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787341, Length=159, Percent_Identity=31.4465408805031, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004622 [H]

Pfam domain/function: NA

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 35962; Mature: 35831

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFSDVLGHERIVDILLRSLRTGKTAHAYIFEGPSGCGRRKTALALVQALFCGAGTNDAC
CCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCC
GVCPSCRKVAAGNHADIHLVNPLPDKRDISISQLRDVQRDLAMRPYEAPRAACIIEPADR
CCCCHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCHHH
MNTSSANSFLKTLEEPPGNAIIILITENADMLLPTIRSRCQLLRFAPLSPEQIRLLLERD
CCCHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
GMDSATASLLAPLSDGSMQRALELDNDSLAQRRDLLLRRLEQLSLERVVTIFESSEELSG
CCCHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCC
SRDETLENLDMLLSFSRDMVHLAAGCSDITNRTIRPTLERLSCRLDLPGALRLADSILDT
CHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
RRSIQRNANAKLALDHLFMNIAAALAA
HHHHHHCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PFSDVLGHERIVDILLRSLRTGKTAHAYIFEGPSGCGRRKTALALVQALFCGAGTNDAC
CCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCC
GVCPSCRKVAAGNHADIHLVNPLPDKRDISISQLRDVQRDLAMRPYEAPRAACIIEPADR
CCCCHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCHHH
MNTSSANSFLKTLEEPPGNAIIILITENADMLLPTIRSRCQLLRFAPLSPEQIRLLLERD
CCCHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
GMDSATASLLAPLSDGSMQRALELDNDSLAQRRDLLLRRLEQLSLERVVTIFESSEELSG
CCCHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCC
SRDETLENLDMLLSFSRDMVHLAAGCSDITNRTIRPTLERLSCRLDLPGALRLADSILDT
CHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
RRSIQRNANAKLALDHLFMNIAAALAA
HHHHHHCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]