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The map label for this gene is virA [H]

Identifier: 118580025

GI number: 118580025

Start: 1715752

End: 1716954

Strand: Direct

Name: virA [H]

Synonym: Ppro_1602

Alternate gene names: 118580025

Gene position: 1715752-1716954 (Clockwise)

Preceding gene: 118580024

Following gene: 118580026

Centisome position: 42.81

GC content: 55.36

Gene sequence:

>1203_bases
ATGTCCCCCTTGTTTAGTCAGGCATGTACAAACAACATGGCAATGAGAATGAGAACGATTCGCGAAGAAAACATGAGCCG
GTCGCAAAAACTGGAGTGCATCGGGACACTGGCTGGTGGAGTTGCCCATGATTTCAACAATATCCTGACGGTAATCATCG
GCGCCTGTACCCTGCTGGAAATGAACGCGGCCGATTATCCCGATCAGATGCCGTTCGTCTCCCGGATTCGCAATTATGCC
GAACGGGCCGCGCAGCTTACCCAAGATCTTCTGATATTCAGTCGCAGGCAGGCGGTTGTCATGGGGCCCGAGAATCTAGT
GGAGGTCTTTCATGACATGCATCGTTTTCTGGGGAGCATCATCGGCGAAGATATTCAGCTGATAACCGACCAGCAGGAGA
AAACGGTGATGGTTATGGTTGATCTCGGGCAGATTGAGCAGGTTCTCATGAATCTGGCGGCCAACTCCCGTGACGCCATG
CCCCGCGGCGGTGTTCTGCGCATGCGTCTGTCGCGGGTTACGAATGATGGAGCTCTGCCCCATCTAGAAGGTTGCCCTTT
GGGTGACTATGCCCTGATGACGGTATCCGATACCGGAACAGGAATCGACAGGGAGAACCTCTGCCGAATCTACGAACCTT
ATTTCACCACCAAGGAACTGCACGCCGGAGCCGGTCTCGGCCTCTCCGTCGTGTACGGCATCATCAGCCAACATAACGGC
GCCATACATGTGCAGAGCAGTCCGGGTGAGGGAACACTATTTAGCATATACCTGCCGATATGCGATCAGGAGGAGATGGT
GATGTCAGAAACTGGCGCAGGGCTATTACCGGGGGGCACGGAAACCATCCTGTTGGTTGACAGTGACCCGGTCATGTTGA
AAATCAATGCCAGCCTTCTGGAGGGGGCGGGCTACATGGTCCTGACTGCTTCGGATGGTCTGGAAGCGCAGGAACTGCTT
CGACGCGGGCAGGAAGCGATTTCGCTGGTTGTGCTTGATGAGGCGCTGCTTCCCGTACATGATCTGGAGACCTGCTGGCG
GCAGCTTGCAAACGATGACAAAATCAAGTTCATGCTGCTCCAGGGAACCGACGACGCGGGGACAGCGCGTACGATGAAGG
GGGCTGCCAGGATCACGAAGCCTCTTGATCCCCTGCTGCTTTTGGAACAGGTTCGCGCCTTGATCGATGGGCGTACCCTC
TGA

Upstream 100 bases:

>100_bases
CGCCCCCCTTTTTTTTAACCGGTCCGAGAGATAACTGTTTTTTGTGGAGAGTGTGAAGGTCAAGACCTCCGAGGTTTCGA
CAGTCTCGGAGGTCTTGTTC

Downstream 100 bases:

>100_bases
TATGGACGGAGCGTGACATTTTTTTTTTCAATGGTATAGTGCAGGCAATAAATTTTATTTTGGAAGGTAGTGTCAATGAA
ATCAAGGTTATCCCTCGTTG

Product: histidine kinase

Products: NA

Alternate protein names: WHR virA [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSPLFSQACTNNMAMRMRTIREENMSRSQKLECIGTLAGGVAHDFNNILTVIIGACTLLEMNAADYPDQMPFVSRIRNYA
ERAAQLTQDLLIFSRRQAVVMGPENLVEVFHDMHRFLGSIIGEDIQLITDQQEKTVMVMVDLGQIEQVLMNLAANSRDAM
PRGGVLRMRLSRVTNDGALPHLEGCPLGDYALMTVSDTGTGIDRENLCRIYEPYFTTKELHAGAGLGLSVVYGIISQHNG
AIHVQSSPGEGTLFSIYLPICDQEEMVMSETGAGLLPGGTETILLVDSDPVMLKINASLLEGAGYMVLTASDGLEAQELL
RRGQEAISLVVLDEALLPVHDLETCWRQLANDDKIKFMLLQGTDDAGTARTMKGAARITKPLDPLLLLEQVRALIDGRTL

Sequences:

>Translated_400_residues
MSPLFSQACTNNMAMRMRTIREENMSRSQKLECIGTLAGGVAHDFNNILTVIIGACTLLEMNAADYPDQMPFVSRIRNYA
ERAAQLTQDLLIFSRRQAVVMGPENLVEVFHDMHRFLGSIIGEDIQLITDQQEKTVMVMVDLGQIEQVLMNLAANSRDAM
PRGGVLRMRLSRVTNDGALPHLEGCPLGDYALMTVSDTGTGIDRENLCRIYEPYFTTKELHAGAGLGLSVVYGIISQHNG
AIHVQSSPGEGTLFSIYLPICDQEEMVMSETGAGLLPGGTETILLVDSDPVMLKINASLLEGAGYMVLTASDGLEAQELL
RRGQEAISLVVLDEALLPVHDLETCWRQLANDDKIKFMLLQGTDDAGTARTMKGAARITKPLDPLLLLEQVRALIDGRTL
>Mature_399_residues
SPLFSQACTNNMAMRMRTIREENMSRSQKLECIGTLAGGVAHDFNNILTVIIGACTLLEMNAADYPDQMPFVSRIRNYAE
RAAQLTQDLLIFSRRQAVVMGPENLVEVFHDMHRFLGSIIGEDIQLITDQQEKTVMVMVDLGQIEQVLMNLAANSRDAMP
RGGVLRMRLSRVTNDGALPHLEGCPLGDYALMTVSDTGTGIDRENLCRIYEPYFTTKELHAGAGLGLSVVYGIISQHNGA
IHVQSSPGEGTLFSIYLPICDQEEMVMSETGAGLLPGGTETILLVDSDPVMLKINASLLEGAGYMVLTASDGLEAQELLR
RGQEAISLVVLDEALLPVHDLETCWRQLANDDKIKFMLLQGTDDAGTARTMKGAARITKPLDPLLLLEQVRALIDGRTL

Specific function: Activates virG, by phosphorylating it, in the presence of acetosyringone or hydroxysyringone [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=247, Percent_Identity=28.7449392712551, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1788549, Length=245, Percent_Identity=28.1632653061224, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1790300, Length=252, Percent_Identity=30.1587301587302, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87081816, Length=325, Percent_Identity=25.2307692307692, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=24.0343347639485, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1788713, Length=187, Percent_Identity=28.3422459893048, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 43808; Mature: 43677

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPLFSQACTNNMAMRMRTIREENMSRSQKLECIGTLAGGVAHDFNNILTVIIGACTLLE
CCCHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
MNAADYPDQMPFVSRIRNYAERAAQLTQDLLIFSRRQAVVMGPENLVEVFHDMHRFLGSI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHH
IGEDIQLITDQQEKTVMVMVDLGQIEQVLMNLAANSRDAMPRGGVLRMRLSRVTNDGALP
HCCCCEEEECCCCCEEEEEEEHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHCCCCCCC
HLEGCPLGDYALMTVSDTGTGIDRENLCRIYEPYFTTKELHAGAGLGLSVVYGIISQHNG
CCCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHCCCC
AIHVQSSPGEGTLFSIYLPICDQEEMVMSETGAGLLPGGTETILLVDSDPVMLKINASLL
EEEEECCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEEEHHHH
EGAGYMVLTASDGLEAQELLRRGQEAISLVVLDEALLPVHDLETCWRQLANDDKIKFMLL
CCCCEEEEEECCCCCHHHHHHCCHHHEEEEEECCHHCCHHHHHHHHHHHCCCCCEEEEEE
QGTDDAGTARTMKGAARITKPLDPLLLLEQVRALIDGRTL
ECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SPLFSQACTNNMAMRMRTIREENMSRSQKLECIGTLAGGVAHDFNNILTVIIGACTLLE
CCHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
MNAADYPDQMPFVSRIRNYAERAAQLTQDLLIFSRRQAVVMGPENLVEVFHDMHRFLGSI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHH
IGEDIQLITDQQEKTVMVMVDLGQIEQVLMNLAANSRDAMPRGGVLRMRLSRVTNDGALP
HCCCCEEEECCCCCEEEEEEEHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHCCCCCCC
HLEGCPLGDYALMTVSDTGTGIDRENLCRIYEPYFTTKELHAGAGLGLSVVYGIISQHNG
CCCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHCCCC
AIHVQSSPGEGTLFSIYLPICDQEEMVMSETGAGLLPGGTETILLVDSDPVMLKINASLL
EEEEECCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEEEHHHH
EGAGYMVLTASDGLEAQELLRRGQEAISLVVLDEALLPVHDLETCWRQLANDDKIKFMLL
CCCCEEEEEECCCCCHHHHHHCCHHHEEEEEECCHHCCHHHHHHHHHHHCCCCCEEEEEE
QGTDDAGTARTMKGAARITKPLDPLLLLEQVRALIDGRTL
ECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2796735; 2194232; 11743193; 11743194 [H]