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The map label for this gene is comEB [H]

Identifier: 118580021

GI number: 118580021

Start: 1707605

End: 1708072

Strand: Reverse

Name: comEB [H]

Synonym: Ppro_1598

Alternate gene names: 118580021

Gene position: 1708072-1707605 (Counterclockwise)

Preceding gene: 118580039

Following gene: 118580020

Centisome position: 42.62

GC content: 64.53

Gene sequence:

>468_bases
ATGCAACGCCCCTCCTGGGACAGGTACTTCATCGACATAACTCGCCTGGTGGCCACCCGCTCCACCTGTCTGCGCCGGGG
CGTGGGAGCGCTTCTGGTCAAGGATCGCAATATCCTGGCCACCGGCTACAACGGCGCGCCATCGGGCATCAGCCACTGCA
GCGAGGCGGGGTGCCTCAGGGAACGCCTGAACGTCCCTTCGGGGGAGCGCCATGAACTCTGCCGCGGCCTGCACGCCGAG
CAGAACGCCATCATCCAGGCGGCACGGCACGGCGTCAACATCGACGGCGCCACGCTCTACTGCACCACCATGCCCTGCGT
GATCTGCACCAAGATGCTGATCAATGCCGGCATACGGCGGGTGGTCTTCGACGAGGGGTATGCCGACGACCTGGCCCGGG
AGATGATCGCGGAATCGGGAATCAAGGTAGTCCACTTCCAGCGGGACTCCGGGGAGGATGAATCATGA

Upstream 100 bases:

>100_bases
CGCACCTCTTCGCAAAAGCCTCTCCCATTCCTGTATTGACCTGACCGCGAGACTGGGGTAACTTGACCGCCACATTAGCA
ATCGGAAGGAATGCACACCC

Downstream 100 bases:

>100_bases
AATGCCCGTTCTGCGGCAACTCCGACAGCAAGGTGGTGGATTCCCGGCCGGACAAGGGGGGCAGCGGCATACGCAGGCGG
CGTGAGTGCGAACAGTGCGC

Product: CMP/dCMP deaminase

Products: dUMP; NH3

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MQRPSWDRYFIDITRLVATRSTCLRRGVGALLVKDRNILATGYNGAPSGISHCSEAGCLRERLNVPSGERHELCRGLHAE
QNAIIQAARHGVNIDGATLYCTTMPCVICTKMLINAGIRRVVFDEGYADDLAREMIAESGIKVVHFQRDSGEDES

Sequences:

>Translated_155_residues
MQRPSWDRYFIDITRLVATRSTCLRRGVGALLVKDRNILATGYNGAPSGISHCSEAGCLRERLNVPSGERHELCRGLHAE
QNAIIQAARHGVNIDGATLYCTTMPCVICTKMLINAGIRRVVFDEGYADDLAREMIAESGIKVVHFQRDSGEDES
>Mature_155_residues
MQRPSWDRYFIDITRLVATRSTCLRRGVGALLVKDRNILATGYNGAPSGISHCSEAGCLRERLNVPSGERHELCRGLHAE
QNAIIQAARHGVNIDGATLYCTTMPCVICTKMLINAGIRRVVFDEGYADDLAREMIAESGIKVVHFQRDSGEDES

Specific function: Dispensable for transformability [H]

COG id: COG2131

COG function: function code F; Deoxycytidylate deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6321938, Length=147, Percent_Identity=38.7755102040816, Blast_Score=116, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24667298, Length=130, Percent_Identity=36.1538461538462, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24667302, Length=130, Percent_Identity=36.1538461538462, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013404
- InterPro:   IPR015517
- InterPro:   IPR016193
- InterPro:   IPR016473 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.12

Molecular weight: Translated: 17121; Mature: 17121

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRPSWDRYFIDITRLVATRSTCLRRGVGALLVKDRNILATGYNGAPSGISHCSEAGCLR
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEEECCCCCCHHHHHHHHHHHHH
ERLNVPSGERHELCRGLHAEQNAIIQAARHGVNIDGATLYCTTMPCVICTKMLINAGIRR
HHCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
VVFDEGYADDLAREMIAESGIKVVHFQRDSGEDES
HHCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MQRPSWDRYFIDITRLVATRSTCLRRGVGALLVKDRNILATGYNGAPSGISHCSEAGCLR
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEEECCCCCCHHHHHHHHHHHHH
ERLNVPSGERHELCRGLHAEQNAIIQAARHGVNIDGATLYCTTMPCVICTKMLINAGIRR
HHCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
VVFDEGYADDLAREMIAESGIKVVHFQRDSGEDES
HHCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dCMP; H2O

Specific reaction: dCMP + H2O = dUMP + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377 [H]