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The map label for this gene is dinB [H]

Identifier: 118579997

GI number: 118579997

Start: 1678265

End: 1679497

Strand: Direct

Name: dinB [H]

Synonym: Ppro_1574

Alternate gene names: 118579997

Gene position: 1678265-1679497 (Clockwise)

Preceding gene: 118579996

Following gene: 118580006

Centisome position: 41.87

GC content: 63.18

Gene sequence:

>1233_bases
ATGGACGGTCGCGTCATTCTTCATATGGACATGAATGCCTTCTTCGCCTCGGTGGAGCAACAGGCCAACCCGGAGCTGCG
CGGCAAGCCGATCGCCGTGGTCGGTTCCGGCGCACGCAGCGTCATAACCACGGCCTCCTACGAGGCCAGGCGGCTGGGGG
TCAAAACCGGTATGGCGATCTGGGAGGCCAGACGCTGCTGCCCGCAGCTGACCCTGGTGGTGGGGGACAACCGCAAGTAC
ACCTCAACCTCCCGGCGGATCATGGAGATGATGGGAGAATACACCCCTGCACTGGAGGTCTTTTCCATCGATGAGGCCTT
CCTGGACGTCACCCACAGTCTCAACCTGTTCGGCAGCGCGGAACGCATCGCCTGCCTGATAAAGGCGCGCATCCTGCACA
CCTTCGGCCTCACCTGCTCCATCGGCATCGCCCCCAACAAGCTCCTGGCCAAGATGGCCAGCGACATGAAGAAGCCGGAC
GGGTTGACCGTTATTCAGCCTGGGGAGATTACGCGCACCATGGAGCGGTTGCCGGTGGCGGAACTGTGCGGAATCGGCAG
GAGCATGGAGCGGAATCTGCTGCTGATGGGCATCCGCACCTGTGGAGAGCTGGGGCGCTGTGACGAGGAGCGCCTGACCC
GCAGATTCGGCATCGTCGGCAAACGGTTGAAGGAGATGGGGCAGGGGATCGACGACAGCCCGGTCATACCCCAGGAGGAA
CAGGAGGAGGTCAAGAGCGTGGGGCACTCCATGACCCTGGCGCGTGATATCCTCCAGCGCCAGGATATCCTGAAATTCCT
GCTGCAGCTCTCCGAGATGGTCGGCAGGCGGGCGCGGCGTTACGGCGTGTCCGGCAGGACGGTCCACCTGTACGTCCGCT
TCGCCGATTTCTATTCCAGCGTCGGCCGGCAGGAGACACTGCCGGGATACATCAGTCGCAGCGAGGATATCTACCGGGCG
GCGGTGGCCATTCTTGATACGTTGGAATTGCCCCAGGCGGTGCGGCTTCTGGGGGTCAGGCTGACGAACCTGCGGCACCA
GGGCGAACAGTTACCCCTCTTCGAGGATGAGCGCCGCAGGTCCCGCATGGTGCGGGCCATGGATGAGGTCAACGACCGTT
TTGGCGATTTCACCCTGACCTTCGGAAGCCTCCTGACCAGCCGGGAAAAGGGGAGCCAGGTTATCTCCCCGGCCTGGCGG
CCGCAGGGGATCAGGAACGTGGATGTGCGCTGA

Upstream 100 bases:

>100_bases
CTGCACTTTACCGTCACCGATGAGGGGGGGCTGTTTGAACTGACCTACAACACCCATGACCAGACCTGGCAGTTGCGGGG
GATTGAGGTGGAGTAGCCTG

Downstream 100 bases:

>100_bases
GAGGGTGAGGAGTGAGGCTGCCCGGGGAGAGAGCTGAACCGCTCTCTCCCCCGAGGTTCACATCTTGTGGCACTTCTCGC
AGTCCCCGGCAACGGAGAAG

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MDGRVILHMDMNAFFASVEQQANPELRGKPIAVVGSGARSVITTASYEARRLGVKTGMAIWEARRCCPQLTLVVGDNRKY
TSTSRRIMEMMGEYTPALEVFSIDEAFLDVTHSLNLFGSAERIACLIKARILHTFGLTCSIGIAPNKLLAKMASDMKKPD
GLTVIQPGEITRTMERLPVAELCGIGRSMERNLLLMGIRTCGELGRCDEERLTRRFGIVGKRLKEMGQGIDDSPVIPQEE
QEEVKSVGHSMTLARDILQRQDILKFLLQLSEMVGRRARRYGVSGRTVHLYVRFADFYSSVGRQETLPGYISRSEDIYRA
AVAILDTLELPQAVRLLGVRLTNLRHQGEQLPLFEDERRRSRMVRAMDEVNDRFGDFTLTFGSLLTSREKGSQVISPAWR
PQGIRNVDVR

Sequences:

>Translated_410_residues
MDGRVILHMDMNAFFASVEQQANPELRGKPIAVVGSGARSVITTASYEARRLGVKTGMAIWEARRCCPQLTLVVGDNRKY
TSTSRRIMEMMGEYTPALEVFSIDEAFLDVTHSLNLFGSAERIACLIKARILHTFGLTCSIGIAPNKLLAKMASDMKKPD
GLTVIQPGEITRTMERLPVAELCGIGRSMERNLLLMGIRTCGELGRCDEERLTRRFGIVGKRLKEMGQGIDDSPVIPQEE
QEEVKSVGHSMTLARDILQRQDILKFLLQLSEMVGRRARRYGVSGRTVHLYVRFADFYSSVGRQETLPGYISRSEDIYRA
AVAILDTLELPQAVRLLGVRLTNLRHQGEQLPLFEDERRRSRMVRAMDEVNDRFGDFTLTFGSLLTSREKGSQVISPAWR
PQGIRNVDVR
>Mature_410_residues
MDGRVILHMDMNAFFASVEQQANPELRGKPIAVVGSGARSVITTASYEARRLGVKTGMAIWEARRCCPQLTLVVGDNRKY
TSTSRRIMEMMGEYTPALEVFSIDEAFLDVTHSLNLFGSAERIACLIKARILHTFGLTCSIGIAPNKLLAKMASDMKKPD
GLTVIQPGEITRTMERLPVAELCGIGRSMERNLLLMGIRTCGELGRCDEERLTRRFGIVGKRLKEMGQGIDDSPVIPQEE
QEEVKSVGHSMTLARDILQRQDILKFLLQLSEMVGRRARRYGVSGRTVHLYVRFADFYSSVGRQETLPGYISRSEDIYRA
AVAILDTLELPQAVRLLGVRLTNLRHQGEQLPLFEDERRRSRMVRAMDEVNDRFGDFTLTFGSLLTSREKGSQVISPAWR
PQGIRNVDVR

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=341, Percent_Identity=30.4985337243402, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI7706681, Length=342, Percent_Identity=30.4093567251462, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI154350220, Length=399, Percent_Identity=28.8220551378446, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI7705344, Length=112, Percent_Identity=42.8571428571429, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI5729982, Length=120, Percent_Identity=40.8333333333333, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1786425, Length=352, Percent_Identity=38.6363636363636, Blast_Score=211, Evalue=9e-56,
Organism=Escherichia coli, GI1787432, Length=405, Percent_Identity=29.3827160493827, Blast_Score=115, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI193205700, Length=433, Percent_Identity=26.0969976905312, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17537959, Length=241, Percent_Identity=29.045643153527, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115534089, Length=126, Percent_Identity=37.3015873015873, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI193205702, Length=253, Percent_Identity=28.8537549407115, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19923006, Length=416, Percent_Identity=26.4423076923077, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI21355641, Length=356, Percent_Identity=28.3707865168539, Blast_Score=121, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24644984, Length=356, Percent_Identity=28.3707865168539, Blast_Score=121, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24668444, Length=167, Percent_Identity=31.7365269461078, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 46110; Mature: 46110

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS50173 UMUC ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGRVILHMDMNAFFASVEQQANPELRGKPIAVVGSGARSVITTASYEARRLGVKTGMAI
CCCCEEEEECHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHCCHHHHHHHHHHHHHH
WEARRCCPQLTLVVGDNRKYTSTSRRIMEMMGEYTPALEVFSIDEAFLDVTHSLNLFGSA
HHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHCCCH
ERIACLIKARILHTFGLTCSIGIAPNKLLAKMASDMKKPDGLTVIQPGEITRTMERLPVA
HHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHCCHH
ELCGIGRSMERNLLLMGIRTCGELGRCDEERLTRRFGIVGKRLKEMGQGIDDSPVIPQEE
HHHCCCCCCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
QEEVKSVGHSMTLARDILQRQDILKFLLQLSEMVGRRARRYGVSGRTVHLYVRFADFYSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHHH
VGRQETLPGYISRSEDIYRAAVAILDTLELPQAVRLLGVRLTNLRHQGEQLPLFEDERRR
CCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
SRMVRAMDEVNDRFGDFTLTFGSLLTSREKGSQVISPAWRPQGIRNVDVR
HHHHHHHHHHHHHHCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDGRVILHMDMNAFFASVEQQANPELRGKPIAVVGSGARSVITTASYEARRLGVKTGMAI
CCCCEEEEECHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHCCHHHHHHHHHHHHHH
WEARRCCPQLTLVVGDNRKYTSTSRRIMEMMGEYTPALEVFSIDEAFLDVTHSLNLFGSA
HHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHCCCH
ERIACLIKARILHTFGLTCSIGIAPNKLLAKMASDMKKPDGLTVIQPGEITRTMERLPVA
HHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHCCHH
ELCGIGRSMERNLLLMGIRTCGELGRCDEERLTRRFGIVGKRLKEMGQGIDDSPVIPQEE
HHHCCCCCCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
QEEVKSVGHSMTLARDILQRQDILKFLLQLSEMVGRRARRYGVSGRTVHLYVRFADFYSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHHH
VGRQETLPGYISRSEDIYRAAVAILDTLELPQAVRLLGVRLTNLRHQGEQLPLFEDERRR
CCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
SRMVRAMDEVNDRFGDFTLTFGSLLTSREKGSQVISPAWRPQGIRNVDVR
HHHHHHHHHHHHHHCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA