Click here to switch to the map view.

The map label for this gene is fabH [H]

Identifier: 118579939

GI number: 118579939

Start: 1618944

End: 1619972

Strand: Reverse

Name: fabH [H]

Synonym: Ppro_1516

Alternate gene names: 118579939

Gene position: 1619972-1618944 (Counterclockwise)

Preceding gene: 118579940

Following gene: 118579938

Centisome position: 40.42

GC content: 66.28

Gene sequence:

>1029_bases
ATGACCACGGGGGCTGGAATCCTGGGAACCGGTGTCTGCCTGCCGGAACAGCTGCTGACCAACGAAGAGCTCGCCAGCCG
CTTCGGCATCACCACGGAGTGGATCTTCGAGCGCACCGGCATCCGCCAACGCCACATCGCCGCACCGCATCAGGCCTGCT
CCGACCTGGCCATCGTTGCCGCCCGTCGGGCCCTGGCCGCCGCCGATACCCTTCCGGAGGAGATCGGCATGGTCATCGTC
TCCACCATATCCGGCGATTACCCCTCCCCGGCCACGGCGGCGCTCGTCCAGGGCGCCCTGGGGATTCCGGGCGCGATCTG
TTTCGACCTTTCTGCCGCCTGCTCCGGTTTCGTGTATGGGCTCGTGGTCGGCTGTCATGCCGTCACCTGCGGATTCAGCC
GCAAGGTGCTGCTGATCGGCGCGGAGGTGCTGTCCCGCATCGTCAACCCGGACGACTGCGACAGCGTCATCCTGTTCGGC
GACGGCGCCGGCGCGGCGGTGATCGGGCCGGTTCCCGACGGATTCGGCTTGCTGGCGACCGATGCGGGCACCATCGGCAG
CGAACATGAGGCCATCATGGTCCCGGCCGGCGGCAGCCGGTTGCCGCTCTCGGCGGAAGTCCTTGCCGACCAGTTGCAGT
ACGTGCGCATGGACGGGAACCAGGTTTTCGTCTTCGCCATGCGCATCCTGGGCAATTCGGCCATGCGCGCCATGAACAAG
CGGGGATTGACGCCAACGGATATCGCCCTGTTCGTGCCCCACCAGGCAAACCGCCGCATCATCGAGGCCGCGGCCGGCCG
GCTTGACCTGCCGCTGGAGCGGTTTGTCGTCAACCTGGAGCGGATCGGAAACACCTCTTCCGCCTCGATCCCCATTGCCC
TGGACGAGACCATCCGCACGGGGCGGATAGTGCATGGCGACCACCTGATGCTGACCGGATTCGGGGCGGGAGTCAGCTGG
GGGTCGGCATTGCTTCGCTGGCACTCCCCCGGGAGTGACCAAATTCACACCAAAGGAGATGAACCATGA

Upstream 100 bases:

>100_bases
CGGATTACGAGGGGATCAGGCTGTACAGCGCCGGGGCACGGGCGCTTTTGGAATTCATCCGCAACGACCGGGAATCAGTC
CCGGCACCGGGAGGGGTATG

Downstream 100 bases:

>100_bases
CAACACGCGAGAAAATCTGTGAACTGATTCTGAAGACGAGGAAGGGCAAGCTGGCCCCGGAGGACCTGAAACCCGAGGCT
GACCTGCGAAACGATCTGCG

Product: 3-oxoacyl-(acyl-carrier-protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTTGAGILGTGVCLPEQLLTNEELASRFGITTEWIFERTGIRQRHIAAPHQACSDLAIVAARRALAAADTLPEEIGMVIV
STISGDYPSPATAALVQGALGIPGAICFDLSAACSGFVYGLVVGCHAVTCGFSRKVLLIGAEVLSRIVNPDDCDSVILFG
DGAGAAVIGPVPDGFGLLATDAGTIGSEHEAIMVPAGGSRLPLSAEVLADQLQYVRMDGNQVFVFAMRILGNSAMRAMNK
RGLTPTDIALFVPHQANRRIIEAAAGRLDLPLERFVVNLERIGNTSSASIPIALDETIRTGRIVHGDHLMLTGFGAGVSW
GSALLRWHSPGSDQIHTKGDEP

Sequences:

>Translated_342_residues
MTTGAGILGTGVCLPEQLLTNEELASRFGITTEWIFERTGIRQRHIAAPHQACSDLAIVAARRALAAADTLPEEIGMVIV
STISGDYPSPATAALVQGALGIPGAICFDLSAACSGFVYGLVVGCHAVTCGFSRKVLLIGAEVLSRIVNPDDCDSVILFG
DGAGAAVIGPVPDGFGLLATDAGTIGSEHEAIMVPAGGSRLPLSAEVLADQLQYVRMDGNQVFVFAMRILGNSAMRAMNK
RGLTPTDIALFVPHQANRRIIEAAAGRLDLPLERFVVNLERIGNTSSASIPIALDETIRTGRIVHGDHLMLTGFGAGVSW
GSALLRWHSPGSDQIHTKGDEP
>Mature_341_residues
TTGAGILGTGVCLPEQLLTNEELASRFGITTEWIFERTGIRQRHIAAPHQACSDLAIVAARRALAAADTLPEEIGMVIVS
TISGDYPSPATAALVQGALGIPGAICFDLSAACSGFVYGLVVGCHAVTCGFSRKVLLIGAEVLSRIVNPDDCDSVILFGD
GAGAAVIGPVPDGFGLLATDAGTIGSEHEAIMVPAGGSRLPLSAEVLADQLQYVRMDGNQVFVFAMRILGNSAMRAMNKR
GLTPTDIALFVPHQANRRIIEAAAGRLDLPLERFVVNLERIGNTSSASIPIALDETIRTGRIVHGDHLMLTGFGAGVSWG
SALLRWHSPGSDQIHTKGDEP

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=321, Percent_Identity=40.1869158878505, Blast_Score=235, Evalue=4e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 35800; Mature: 35668

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTGAGILGTGVCLPEQLLTNEELASRFGITTEWIFERTGIRQRHIAAPHQACSDLAIVA
CCCCCCCCCCCCCCCHHHHCHHHHHHHHCCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHH
ARRALAAADTLPEEIGMVIVSTISGDYPSPATAALVQGALGIPGAICFDLSAACSGFVYG
HHHHHHHHHCCHHHHCEEEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LVVGCHAVTCGFSRKVLLIGAEVLSRIVNPDDCDSVILFGDGAGAAVIGPVPDGFGLLAT
HHHHHHHHHCCCCCEEEEEEHHHHHHCCCCCCCCEEEEEECCCCCEEECCCCCCCEEEEE
DAGTIGSEHEAIMVPAGGSRLPLSAEVLADQLQYVRMDGNQVFVFAMRILGNSAMRAMNK
CCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHEEECCCEEEEEHHHHHHHHHHHHHHH
RGLTPTDIALFVPHQANRRIIEAAAGRLDLPLERFVVNLERIGNTSSASIPIALDETIRT
CCCCCCCEEEECCCCCCCHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCC
GRIVHGDHLMLTGFGAGVSWGSALLRWHSPGSDQIHTKGDEP
CEEEECCEEEEEECCCCHHHHHHHEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTGAGILGTGVCLPEQLLTNEELASRFGITTEWIFERTGIRQRHIAAPHQACSDLAIVA
CCCCCCCCCCCCCCHHHHCHHHHHHHHCCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHH
ARRALAAADTLPEEIGMVIVSTISGDYPSPATAALVQGALGIPGAICFDLSAACSGFVYG
HHHHHHHHHCCHHHHCEEEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LVVGCHAVTCGFSRKVLLIGAEVLSRIVNPDDCDSVILFGDGAGAAVIGPVPDGFGLLAT
HHHHHHHHHCCCCCEEEEEEHHHHHHCCCCCCCCEEEEEECCCCCEEECCCCCCCEEEEE
DAGTIGSEHEAIMVPAGGSRLPLSAEVLADQLQYVRMDGNQVFVFAMRILGNSAMRAMNK
CCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHEEECCCEEEEEHHHHHHHHHHHHHHH
RGLTPTDIALFVPHQANRRIIEAAAGRLDLPLERFVVNLERIGNTSSASIPIALDETIRT
CCCCCCCEEEECCCCCCCHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCC
GRIVHGDHLMLTGFGAGVSWGSALLRWHSPGSDQIHTKGDEP
CEEEECCEEEEEECCCCHHHHHHHEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]