Click here to switch to the map view.

The map label for this gene is pksC [H]

Identifier: 118579937

GI number: 118579937

Start: 1617736

End: 1618695

Strand: Reverse

Name: pksC [H]

Synonym: Ppro_1514

Alternate gene names: 118579937

Gene position: 1618695-1617736 (Counterclockwise)

Preceding gene: 118579938

Following gene: 118579936

Centisome position: 40.39

GC content: 65.83

Gene sequence:

>960_bases
ATGACGAGCACCACGGGGAAGATCGCCCTCCTCTGTTCCGGCCAAGCCGGGCAGAGAAGCGGCATGCTGGATGAACTTCT
CGGCAACCCGCGACATAACGAACTGTCGCAGCTGGCTTCCGATCTCCTGGGACAGGATGTGTGCTCCTGGTGGCGCTCCC
TCGGAGAAGACGAGATCTATGCCAACAGCCGGGCCCAGTTTACCATCGCCCTCTATCAGCTGGCAACCTGGGACGCCATC
CGCGACCTGCTTCCGAAGCCGGCCCTGGTGGCCGGCTACTCCCTTGGCGAGGTCGCGGCCTGTTACGTCGCCGGCGCCCT
GAACCGGCGGGAAACCCTCCGGATCATCCGGGAACGGGCGCGCCTGATGGATCTGGCAACGGCACAGCTGCGGCCGGGCC
GCGGGGCGATGATGCTATGGCGTTATGACGACGTCCCCGAACGACGGATGCGGCGCGATGCAATGATGGCAGCACTGGGG
ATCGACACGGCAATCGTCCGCGGCAGCGGCGAGGTGGTGCTGTCCGGCCGCGACGACGCGGTCCACCGGCTGCTGGATCA
TTTTTCCCCGACAAATCCGTCCCTGGTTCGTCTTCCCGTCGCTGTTCCCTCCCACAGCCGCCATCTGGCCGGGGCGGTGG
AACCGTTGCGCAGGTTCATCCTGGAAGGAGAATGCGCGGCTCCCGCCGTGCCGCTGCTGTCCAGCCTGTCCGGACAGCGG
ATCACGAGCCGTGAGGGAGTGGCGGAGGCACTGTCGGCCCAGCTCGCGAGCACCGTCCGCTGGGACCTCTGCATGGCGGC
CATGGCACGGGCCGCCATCGACACCGTGATTGAGCTGGGACCCGGGACGGACCTGGCCCGGCTCCTGATGCGCGAGTACC
CCCACATCAGGGTCTGTTCCGTCGATGAATTTCCATGCCTGTCCCGATTCGAGACATGGCTTGAGGAGCATCAAGCATGA

Upstream 100 bases:

>100_bases
CTTCGGCGTGGAATTCTCTCCTGAAGAGGCCCACTCGGTGGCAACCCTGGGGCAGATGATCGACTTCATCGACAAACGCC
TGGCCGCCGCCTAAACCGGC

Downstream 100 bases:

>100_bases
ATGAGGCACGGGAAACAATACGGTTCATCCTCAACGGCCGGGCAATGGCGATCGACGCCCCCGCAGACCGGCGGGTGGTG
GATCTGCTGCGCGAAGACCT

Product: malonyl CoA-ACP transacylase

Products: NA

Alternate protein names: AT [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MTSTTGKIALLCSGQAGQRSGMLDELLGNPRHNELSQLASDLLGQDVCSWWRSLGEDEIYANSRAQFTIALYQLATWDAI
RDLLPKPALVAGYSLGEVAACYVAGALNRRETLRIIRERARLMDLATAQLRPGRGAMMLWRYDDVPERRMRRDAMMAALG
IDTAIVRGSGEVVLSGRDDAVHRLLDHFSPTNPSLVRLPVAVPSHSRHLAGAVEPLRRFILEGECAAPAVPLLSSLSGQR
ITSREGVAEALSAQLASTVRWDLCMAAMARAAIDTVIELGPGTDLARLLMREYPHIRVCSVDEFPCLSRFETWLEEHQA

Sequences:

>Translated_319_residues
MTSTTGKIALLCSGQAGQRSGMLDELLGNPRHNELSQLASDLLGQDVCSWWRSLGEDEIYANSRAQFTIALYQLATWDAI
RDLLPKPALVAGYSLGEVAACYVAGALNRRETLRIIRERARLMDLATAQLRPGRGAMMLWRYDDVPERRMRRDAMMAALG
IDTAIVRGSGEVVLSGRDDAVHRLLDHFSPTNPSLVRLPVAVPSHSRHLAGAVEPLRRFILEGECAAPAVPLLSSLSGQR
ITSREGVAEALSAQLASTVRWDLCMAAMARAAIDTVIELGPGTDLARLLMREYPHIRVCSVDEFPCLSRFETWLEEHQA
>Mature_318_residues
TSTTGKIALLCSGQAGQRSGMLDELLGNPRHNELSQLASDLLGQDVCSWWRSLGEDEIYANSRAQFTIALYQLATWDAIR
DLLPKPALVAGYSLGEVAACYVAGALNRRETLRIIRERARLMDLATAQLRPGRGAMMLWRYDDVPERRMRRDAMMAALGI
DTAIVRGSGEVVLSGRDDAVHRLLDHFSPTNPSLVRLPVAVPSHSRHLAGAVEPLRRFILEGECAAPAVPLLSSLSGQRI
TSREGVAEALSAQLASTVRWDLCMAAMARAAIDTVIELGPGTDLARLLMREYPHIRVCSVDEFPCLSRFETWLEEHQA

Specific function: Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. It catalyzes the transfer of the malonyl-CoA group to the acyl-carrier-protein AcpK (Mal-AcpK) [H]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=299, Percent_Identity=27.0903010033445, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1787334, Length=305, Percent_Identity=25.9016393442623, Blast_Score=82, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24665753, Length=297, Percent_Identity=24.2424242424242, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 35086; Mature: 34955

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTTGKIALLCSGQAGQRSGMLDELLGNPRHNELSQLASDLLGQDVCSWWRSLGEDEIY
CCCCCCCEEEEECCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
ANSRAQFTIALYQLATWDAIRDLLPKPALVAGYSLGEVAACYVAGALNRRETLRIIRERA
CCCCCEEEEHHHHHHHHHHHHHHCCCCHHEECCCHHHHHHHHHHHHCCHHHHHHHHHHHH
RLMDLATAQLRPGRGAMMLWRYDDVPERRMRRDAMMAALGIDTAIVRGSGEVVLSGRDDA
HHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCHHHEEECCCCEEEECCHHH
VHRLLDHFSPTNPSLVRLPVAVPSHSRHLAGAVEPLRRFILEGECAAPAVPLLSSLSGQR
HHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCC
ITSREGVAEALSAQLASTVRWDLCMAAMARAAIDTVIELGPGTDLARLLMREYPHIRVCS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEC
VDEFPCLSRFETWLEEHQA
CCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSTTGKIALLCSGQAGQRSGMLDELLGNPRHNELSQLASDLLGQDVCSWWRSLGEDEIY
CCCCCCEEEEECCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
ANSRAQFTIALYQLATWDAIRDLLPKPALVAGYSLGEVAACYVAGALNRRETLRIIRERA
CCCCCEEEEHHHHHHHHHHHHHHCCCCHHEECCCHHHHHHHHHHHHCCHHHHHHHHHHHH
RLMDLATAQLRPGRGAMMLWRYDDVPERRMRRDAMMAALGIDTAIVRGSGEVVLSGRDDA
HHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCHHHEEECCCCEEEECCHHH
VHRLLDHFSPTNPSLVRLPVAVPSHSRHLAGAVEPLRRFILEGECAAPAVPLLSSLSGQR
HHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCC
ITSREGVAEALSAQLASTVRWDLCMAAMARAAIDTVIELGPGTDLARLLMREYPHIRVCS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEC
VDEFPCLSRFETWLEEHQA
CCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]