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The map label for this gene is xdhB [H]

Identifier: 118579935

GI number: 118579935

Start: 1616403

End: 1617251

Strand: Reverse

Name: xdhB [H]

Synonym: Ppro_1512

Alternate gene names: 118579935

Gene position: 1617251-1616403 (Counterclockwise)

Preceding gene: 118579936

Following gene: 118579934

Centisome position: 40.35

GC content: 68.43

Gene sequence:

>849_bases
ATGAGGATCGTACTTTCCCCCTCGTCCCTGGAGGAGCTCTTCTCCCATCTGGAGCATTTTCCCCAGGCCATGGTCATGGC
CGGCGGCACCGATCTTTTGGTCAGGCTGCGCCAAGAGCCGGTCCCGAACCAGCGCCCCCTCCTGCTACTTGCCGGCCTGC
CGGAGCTCCAGGGCATCAATGACAGGGGAACGGAAATCTCCATCGGCGCCGCCACGCCGCTGGCCCGCCTGATCAGCCAC
CCGCTGGCCCTGGGTCATGCAGAGCTGCTGGTCCGGGCCGCCCGCACCATCGGCGGCCCGGCGATCAGGAACATGGCCAC
CCTGGGGGGCAACATCAGCACCGCATCCCCGGCCGGGGACTCCCTGCCGGCACTGCAGCTGCTGGGCGCTGAACTGGAGC
TGGCCTCCCGGCACGGGACACGCCGGCTGTCCGTGGGAGACTTTGTCGCCGGACCGGGCAGGACGCAGGTGCGCCATGGC
GAGGTCATCACCCGCATCCTGCTGCCCCGGGAGGAGGACTTCCCCCACCAGACCTTCCAGAAGGTCGGTCTGCGCAGTGC
TTTGGCCGTGGCCGTGGTCAGTTTTGCCGGGATGTTCAGGCTTTCCCCCGACGGCTGCGTGCAAGAGGCCCGTTTTGCCT
GGGGGAGCGTGGCGCCCACCGTTGTCAGGCTCCCCGGGCTGGAGGAGAAACTGGCCGGCGCGCCCCTGGACCGGGACACA
ATCCGGTCAGCGGCGGCACTGGTGCGCGAAGGCGTGTCGCCCATGGACGATATCCGCGGCAGCGCCGACTACCGCCGTTC
CGTGGCCGCCAACCTGCTGGTCCGTTTCCTGGAGGGAATCCATGCCTAA

Upstream 100 bases:

>100_bases
GGGAGGGGCTTTCCGGAAACCTCTGCCGCTGCACCGGGTATGTCAAAATCGTGGATGCGGTGGAGCGGGCCGCCACGGAC
ATCGGCGGAGGGGAACAAGA

Downstream 100 bases:

>100_bases
ACCAGCCGGCCTGTTCACGCCCGCCTTTCTGGTGATCAATTTCCAGTTCGCGCTGGTGACCGGCATTGCCGCGCTGTTCT
TCGCCTTCTCAGGCTATCTG

Product: molybdopterin dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MRIVLSPSSLEELFSHLEHFPQAMVMAGGTDLLVRLRQEPVPNQRPLLLLAGLPELQGINDRGTEISIGAATPLARLISH
PLALGHAELLVRAARTIGGPAIRNMATLGGNISTASPAGDSLPALQLLGAELELASRHGTRRLSVGDFVAGPGRTQVRHG
EVITRILLPREEDFPHQTFQKVGLRSALAVAVVSFAGMFRLSPDGCVQEARFAWGSVAPTVVRLPGLEEKLAGAPLDRDT
IRSAAALVREGVSPMDDIRGSADYRRSVAANLLVRFLEGIHA

Sequences:

>Translated_282_residues
MRIVLSPSSLEELFSHLEHFPQAMVMAGGTDLLVRLRQEPVPNQRPLLLLAGLPELQGINDRGTEISIGAATPLARLISH
PLALGHAELLVRAARTIGGPAIRNMATLGGNISTASPAGDSLPALQLLGAELELASRHGTRRLSVGDFVAGPGRTQVRHG
EVITRILLPREEDFPHQTFQKVGLRSALAVAVVSFAGMFRLSPDGCVQEARFAWGSVAPTVVRLPGLEEKLAGAPLDRDT
IRSAAALVREGVSPMDDIRGSADYRRSVAANLLVRFLEGIHA
>Mature_282_residues
MRIVLSPSSLEELFSHLEHFPQAMVMAGGTDLLVRLRQEPVPNQRPLLLLAGLPELQGINDRGTEISIGAATPLARLISH
PLALGHAELLVRAARTIGGPAIRNMATLGGNISTASPAGDSLPALQLLGAELELASRHGTRRLSVGDFVAGPGRTQVRHG
EVITRILLPREEDFPHQTFQKVGLRSALAVAVVSFAGMFRLSPDGCVQEARFAWGSVAPTVVRLPGLEEKLAGAPLDRDT
IRSAAALVREGVSPMDDIRGSADYRRSVAANLLVRFLEGIHA

Specific function: Presumed to be a dehydrogenase, but possibly an oxidase. Participates in limited purine salvage (requires aspartate) but does not support aerobic growth on purines as the sole carbon source (purine catabolism) [H]

COG id: COG1319

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=288, Percent_Identity=24.6527777777778, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI91823271, Length=288, Percent_Identity=27.0833333333333, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1789231, Length=261, Percent_Identity=31.8007662835249, Blast_Score=129, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17540638, Length=289, Percent_Identity=25.9515570934256, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005107
- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR002346 [H]

Pfam domain/function: PF03450 CO_deh_flav_C; PF00941 FAD_binding_5 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 30087; Mature: 30087

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVLSPSSLEELFSHLEHFPQAMVMAGGTDLLVRLRQEPVPNQRPLLLLAGLPELQGIN
CEEEECHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEECCCHHCCCC
DRGTEISIGAATPLARLISHPLALGHAELLVRAARTIGGPAIRNMATLGGNISTASPAGD
CCCCEEEECCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCC
SLPALQLLGAELELASRHGTRRLSVGDFVAGPGRTQVRHGEVITRILLPREEDFPHQTFQ
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHH
KVGLRSALAVAVVSFAGMFRLSPDGCVQEARFAWGSVAPTVVRLPGLEEKLAGAPLDRDT
HHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHCCCCCHHEECCCCHHHHCCCCCCHHH
IRSAAALVREGVSPMDDIRGSADYRRSVAANLLVRFLEGIHA
HHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRIVLSPSSLEELFSHLEHFPQAMVMAGGTDLLVRLRQEPVPNQRPLLLLAGLPELQGIN
CEEEECHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEECCCHHCCCC
DRGTEISIGAATPLARLISHPLALGHAELLVRAARTIGGPAIRNMATLGGNISTASPAGD
CCCCEEEECCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCC
SLPALQLLGAELELASRHGTRRLSVGDFVAGPGRTQVRHGEVITRILLPREEDFPHQTFQ
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHH
KVGLRSALAVAVVSFAGMFRLSPDGCVQEARFAWGSVAPTVVRLPGLEEKLAGAPLDRDT
HHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHCCCCCHHEECCCCHHHHCCCCCCHHH
IRSAAALVREGVSPMDDIRGSADYRRSVAANLLVRFLEGIHA
HHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]