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The map label for this gene is atpB3

Identifier: 118579923

GI number: 118579923

Start: 1607088

End: 1607777

Strand: Direct

Name: atpB3

Synonym: Ppro_1500

Alternate gene names: 118579923

Gene position: 1607088-1607777 (Clockwise)

Preceding gene: 118579922

Following gene: 118579924

Centisome position: 40.1

GC content: 55.36

Gene sequence:

>690_bases
ATGGTTCATCCATTTCTGTTTCTCGAATTTTTACGCAAGATGCTTGCTCCTTTGCATCTGTCCGAGGCCAGCGCCGATGC
GGTCAGTTACACCTGGCTCATCATTGCGCTTCTTCTGCTCCTCTCCTTTCTGGCCACCAGGGCGCTCAAGACGGTCCCTG
GCGGGTTGCAGAACTTCATGGAAATTATTGTGGGCGGCATCGAGAACATGGTTACCGAAACTATGGGAGAGCATGGCCGT
CCCTACTTCCCGCTGGTGGCGACCATCGGTATCTTCGTGCTGGTCTCCAACCTGATCGGCCTGATCCCCGGATTCTTCCC
ACCAACGGCCAATATCAACACCACCGCCGCCTGCGCCATCGTTGTTTTTCTCTCGACCCATGTGGTGGGTATAAAGCGCC
ATGGAATTGGGTACATAAAGCATTTCTGCGGCCCGATTCTCTGGCTGACGCCGATCATGTTCTTCATCGAGGTCATCGGA
CACCTGAGTCGCCCCGTCTCCCTGACCCTGCGTCTGTTCGGTAATATGAACGGCCACGAACTGGTCCTGATCATCTTCTT
CGGTCTGGCGCCCTTCCTGGTGCCGCTGCCGATGATGCTGATGGGGGTATTGGTCTCCTTCATCCAGGCGTTTGTCTTCA
TGCTGCTGACGATGATCTACATCCAGGGGTCGCTTGAAGAGGCCCACTGA

Upstream 100 bases:

>100_bases
TAACTCTTAGGGCTGTTTGTACGGTTGTCAATCAGAAACGTCATAACCATAGAGTGCGGTATTCGATTCTATGGAACTTT
GGATACGGTGGGTTACGCAT

Downstream 100 bases:

>100_bases
TCCACCGGTTGATTCACAACAATTATCAAGATCCTATACTGCTTAGGATACATCACACTCCGAGGAGAAAAGAAAATGAG
TTTTTTCAGTATGTGCGTTC

Product: ATP synthase F0 subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a 3; F-ATPase subunit 6 3

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MVHPFLFLEFLRKMLAPLHLSEASADAVSYTWLIIALLLLLSFLATRALKTVPGGLQNFMEIIVGGIENMVTETMGEHGR
PYFPLVATIGIFVLVSNLIGLIPGFFPPTANINTTAACAIVVFLSTHVVGIKRHGIGYIKHFCGPILWLTPIMFFIEVIG
HLSRPVSLTLRLFGNMNGHELVLIIFFGLAPFLVPLPMMLMGVLVSFIQAFVFMLLTMIYIQGSLEEAH

Sequences:

>Translated_229_residues
MVHPFLFLEFLRKMLAPLHLSEASADAVSYTWLIIALLLLLSFLATRALKTVPGGLQNFMEIIVGGIENMVTETMGEHGR
PYFPLVATIGIFVLVSNLIGLIPGFFPPTANINTTAACAIVVFLSTHVVGIKRHGIGYIKHFCGPILWLTPIMFFIEVIG
HLSRPVSLTLRLFGNMNGHELVLIIFFGLAPFLVPLPMMLMGVLVSFIQAFVFMLLTMIYIQGSLEEAH
>Mature_229_residues
MVHPFLFLEFLRKMLAPLHLSEASADAVSYTWLIIALLLLLSFLATRALKTVPGGLQNFMEIIVGGIENMVTETMGEHGR
PYFPLVATIGIFVLVSNLIGLIPGFFPPTANINTTAACAIVVFLSTHVVGIKRHGIGYIKHFCGPILWLTPIMFFIEVIG
HLSRPVSLTLRLFGNMNGHELVLIIFFGLAPFLVPLPMMLMGVLVSFIQAFVFMLLTMIYIQGSLEEAH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family

Homologues:

Organism=Escherichia coli, GI1790176, Length=208, Percent_Identity=32.2115384615385, Blast_Score=89, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6226527, Length=183, Percent_Identity=28.9617486338798, Blast_Score=72, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATP63_PELPD (A1AP45)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_901173.1
- ProteinModelPortal:   A1AP45
- SMR:   A1AP45
- STRING:   A1AP45
- GeneID:   4572175
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_1500
- eggNOG:   COG0356
- HOGENOM:   HBG734175
- OMA:   YIFTILT
- PhylomeDB:   A1AP45
- ProtClustDB:   CLSK924394
- HAMAP:   MF_01393
- InterPro:   IPR000568
- InterPro:   IPR023011
- Gene3D:   G3DSA:1.20.120.220
- PANTHER:   PTHR11410
- PRINTS:   PR00123
- TIGRFAMs:   TIGR01131

Pfam domain/function: PF00119 ATP-synt_A; SSF81336 ATPase_F0_A

EC number: 3.6.3.14

Molecular weight: Translated: 25296; Mature: 25296

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x236ef564)-; HASH(0x2449c660)-; HASH(0x23713cfc)-; HASH(0x249e4898)-; HASH(0x2472823c)-; HASH(0x2472829c)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHPFLFLEFLRKMLAPLHLSEASADAVSYTWLIIALLLLLSFLATRALKTVPGGLQNFM
CCCHHHHHHHHHHHHCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
EIIVGGIENMVTETMGEHGRPYFPLVATIGIFVLVSNLIGLIPGFFPPTANINTTAACAI
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
VVFLSTHVVGIKRHGIGYIKHFCGPILWLTPIMFFIEVIGHLSRPVSLTLRLFGNMNGHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHH
LVLIIFFGLAPFLVPLPMMLMGVLVSFIQAFVFMLLTMIYIQGSLEEAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCH
>Mature Secondary Structure
MVHPFLFLEFLRKMLAPLHLSEASADAVSYTWLIIALLLLLSFLATRALKTVPGGLQNFM
CCCHHHHHHHHHHHHCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
EIIVGGIENMVTETMGEHGRPYFPLVATIGIFVLVSNLIGLIPGFFPPTANINTTAACAI
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
VVFLSTHVVGIKRHGIGYIKHFCGPILWLTPIMFFIEVIGHLSRPVSLTLRLFGNMNGHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHH
LVLIIFFGLAPFLVPLPMMLMGVLVSFIQAFVFMLLTMIYIQGSLEEAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA