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The map label for this gene is zraS [C]

Identifier: 118579852

GI number: 118579852

Start: 1526935

End: 1529010

Strand: Reverse

Name: zraS [C]

Synonym: Ppro_1428

Alternate gene names: 118579852

Gene position: 1529010-1526935 (Counterclockwise)

Preceding gene: 118579853

Following gene: 118579850

Centisome position: 38.15

GC content: 58.62

Gene sequence:

>2076_bases
GTGAACGAAGAATCCATTACACCGCCGGGAGAACTGGAAACGCTGCGCGGCAGGGTGACCGACCTTGCCCGGGATAATGC
CCACCTGAAACTGATCAACCGCATGCTGCTCAGCCTCACTTCGGCCAGTGGCCTGGAAAACGTTGTTGAGCAGATCCTTC
GAACCCTGATGGAAACCATCGGCGCGTTCAATCTGCTGGTTTACTACCTCGTCGATGGCCGTTGGCACTGCCGCGATCTC
TTCGGAAGCGCCCGTGAGATGGAGTCGCCCGACACCCCCCTGGTAGCAGCCTGCGTACGGGAGCGTATCTTCCAGCGGGA
ACAGCAGGATGCGCGGGAGTTTCTCCCCGGTGACAGTCGCCCGGAGAACTGGGCCTTTCCCCTGCTGGTGCAGCAGCGTC
TGGTGGGAGTCGTGGTGATGGAGGGGATGATCATCGCTCACGACTCCATCCGCATCCAACTGCAGCCATTCTTCGTCTAC
GCAGCCTTGATGCTCGGCAACGAGATCTCCAACTACAGTGTGCTGGAACAGACCCACCAACAACTGCTCCAGACACATCA
AGCCCTGGAACGAGAAACGACTGCTCGCCAGGAGGCGGAGAAACTGTACCGCATGCTCTTCGAGCAGTCCCCTGACGGCA
TCATGCTGATCGACCCCGAATCCTTGAGAACACTCCGTTGCAACCATGCCGCCCACCGGATGCTGGGCTATTCCCTCGAC
GAGTTCGCGGCCCTGGCGATACCGGACGTTGCGGCGCAGGATGATCGGAATGAGGTTGCTCGGCGCGTCCGAATTGCTTT
GGAGCGTGGGGACCACACCTTCGAGGCCAGATTGTGCGCCAAAGGTGGGGAGTTCCGCGATGTGCTGGTGACCATGAGGA
TGATGACAACAGCCGGGCGCCCCCTACTGCACACCATCTGCCGCGACATTACCGATACCAAGAAGATGGAACAGGACCTC
TTCAAGAACCAGAAGATGGAATCCATCGGCCTTCTTGCCGGCGGTATCGCCCACGACTTCAACAACCTGCTGGCCGCCAT
CATGGGCAATATCTCGCTTGCCTCCATGTTACTCCAGCCTGGCTCCCGTTCGGTTTCTCTACTGGCCGAAAGCGAAAAGG
CTTGTTTGCGCGCCCGCGACCTGACCCTCCAGCTACTGACCTTCTCCAAAGGGGGCGCTCCGGTCAGGAGGCTTGCCTCC
GTCGAGCAGATCGTGAGGGAGAGCGCCTCCTTTGTCGTACGAGGAAGCGGAACCTTCTGCAACTTCCACGTAGCCAACGG
ACTCTGGCAGGCGGAAATAGACGAGGGACAGATCAGCCAAGTGATCCACAACCTGGTGATCAACGCGGTGCAGGCCATGC
CACACGGTGGAGTCATCACCATCACCTGCAGCAACGTTGCCGCTGTCACGGAGGGGGAGGCAGACCTTGTCAGGATCGAC
ATAGAAGATCAGGGAGAAGGGATTACGCCCGAGGTCCTGCCCCGCATCTTCGATCCCTACTTCACCACAAAGCGGCAAGG
TAGTGGCCTAGGACTGGCATCCTCCTACTCCATTATCAGAAATCATGGCGGTTACATCGAAGTTAATTCGCCGCCCGGTA
AGGGAGCCATCTTCAGCATCTTTCTCCCGGCCACGGTGGCCACTGTACTCCCTCCCTCGGTCGAACCCCATCAGATCCTG
ACACGCCCTTGCAAAATCCTGGTTATGGATGATGAGGAAATGCTGCGGGACGTCATCACCTCCATGCTGAATATGCTGGG
GCACCGGGTTGAAACAGCCTGCGACGGAAAAGAGACTCTGACCCGTTACCAGCGGGCTCGAGACAGTAGAGACCCCTTCG
ATGCGGTCATTCTTGATTTGACGGTCCCGGGAGGAATGGGGGGCAGGGAAACCATGGCGCGCCTGCGGGAAATCGACCCG
GAGGTAAAGGGGATAGTCTCCAGCGGCTATGCCAGTGACATGGCACTGCCCGATTTCCGCAGTCACGGGTTCTGCACCAT
TCTATCCAAACCCTACAGCATGCAGGATCTGATCAGGGTGCTGGAGGAACTGTTTACCCAAGACGCTCCCACCTGA

Upstream 100 bases:

>100_bases
CCCGCAGCACCACTCTGGACCTGCGCTGGATCGATGTCGGGCTTGAGGAACTGGAACGGACCCTGAAGGCAACCATCCGG
GCCGCGTTCAAGGACGCTAC

Downstream 100 bases:

>100_bases
CGATCATCCCCGACTGCAGACCGCCAGCACCTCATCGGATCACCCGAAACAAGACTACTCGACATTTCTGCACCAAAAGC
CTTGTGCCACAAAGGCATCA

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 691; Mature: 691

Protein sequence:

>691_residues
MNEESITPPGELETLRGRVTDLARDNAHLKLINRMLLSLTSASGLENVVEQILRTLMETIGAFNLLVYYLVDGRWHCRDL
FGSAREMESPDTPLVAACVRERIFQREQQDAREFLPGDSRPENWAFPLLVQQRLVGVVVMEGMIIAHDSIRIQLQPFFVY
AALMLGNEISNYSVLEQTHQQLLQTHQALERETTARQEAEKLYRMLFEQSPDGIMLIDPESLRTLRCNHAAHRMLGYSLD
EFAALAIPDVAAQDDRNEVARRVRIALERGDHTFEARLCAKGGEFRDVLVTMRMMTTAGRPLLHTICRDITDTKKMEQDL
FKNQKMESIGLLAGGIAHDFNNLLAAIMGNISLASMLLQPGSRSVSLLAESEKACLRARDLTLQLLTFSKGGAPVRRLAS
VEQIVRESASFVVRGSGTFCNFHVANGLWQAEIDEGQISQVIHNLVINAVQAMPHGGVITITCSNVAAVTEGEADLVRID
IEDQGEGITPEVLPRIFDPYFTTKRQGSGLGLASSYSIIRNHGGYIEVNSPPGKGAIFSIFLPATVATVLPPSVEPHQIL
TRPCKILVMDDEEMLRDVITSMLNMLGHRVETACDGKETLTRYQRARDSRDPFDAVILDLTVPGGMGGRETMARLREIDP
EVKGIVSSGYASDMALPDFRSHGFCTILSKPYSMQDLIRVLEELFTQDAPT

Sequences:

>Translated_691_residues
MNEESITPPGELETLRGRVTDLARDNAHLKLINRMLLSLTSASGLENVVEQILRTLMETIGAFNLLVYYLVDGRWHCRDL
FGSAREMESPDTPLVAACVRERIFQREQQDAREFLPGDSRPENWAFPLLVQQRLVGVVVMEGMIIAHDSIRIQLQPFFVY
AALMLGNEISNYSVLEQTHQQLLQTHQALERETTARQEAEKLYRMLFEQSPDGIMLIDPESLRTLRCNHAAHRMLGYSLD
EFAALAIPDVAAQDDRNEVARRVRIALERGDHTFEARLCAKGGEFRDVLVTMRMMTTAGRPLLHTICRDITDTKKMEQDL
FKNQKMESIGLLAGGIAHDFNNLLAAIMGNISLASMLLQPGSRSVSLLAESEKACLRARDLTLQLLTFSKGGAPVRRLAS
VEQIVRESASFVVRGSGTFCNFHVANGLWQAEIDEGQISQVIHNLVINAVQAMPHGGVITITCSNVAAVTEGEADLVRID
IEDQGEGITPEVLPRIFDPYFTTKRQGSGLGLASSYSIIRNHGGYIEVNSPPGKGAIFSIFLPATVATVLPPSVEPHQIL
TRPCKILVMDDEEMLRDVITSMLNMLGHRVETACDGKETLTRYQRARDSRDPFDAVILDLTVPGGMGGRETMARLREIDP
EVKGIVSSGYASDMALPDFRSHGFCTILSKPYSMQDLIRVLEELFTQDAPT
>Mature_691_residues
MNEESITPPGELETLRGRVTDLARDNAHLKLINRMLLSLTSASGLENVVEQILRTLMETIGAFNLLVYYLVDGRWHCRDL
FGSAREMESPDTPLVAACVRERIFQREQQDAREFLPGDSRPENWAFPLLVQQRLVGVVVMEGMIIAHDSIRIQLQPFFVY
AALMLGNEISNYSVLEQTHQQLLQTHQALERETTARQEAEKLYRMLFEQSPDGIMLIDPESLRTLRCNHAAHRMLGYSLD
EFAALAIPDVAAQDDRNEVARRVRIALERGDHTFEARLCAKGGEFRDVLVTMRMMTTAGRPLLHTICRDITDTKKMEQDL
FKNQKMESIGLLAGGIAHDFNNLLAAIMGNISLASMLLQPGSRSVSLLAESEKACLRARDLTLQLLTFSKGGAPVRRLAS
VEQIVRESASFVVRGSGTFCNFHVANGLWQAEIDEGQISQVIHNLVINAVQAMPHGGVITITCSNVAAVTEGEADLVRID
IEDQGEGITPEVLPRIFDPYFTTKRQGSGLGLASSYSIIRNHGGYIEVNSPPGKGAIFSIFLPATVATVLPPSVEPHQIL
TRPCKILVMDDEEMLRDVITSMLNMLGHRVETACDGKETLTRYQRARDSRDPFDAVILDLTVPGGMGGRETMARLREIDP
EVKGIVSSGYASDMALPDFRSHGFCTILSKPYSMQDLIRVLEELFTQDAPT

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=310, Percent_Identity=28.0645161290323, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI1788549, Length=377, Percent_Identity=29.4429708222812, Blast_Score=112, Evalue=9e-26,
Organism=Escherichia coli, GI48994928, Length=566, Percent_Identity=25.0883392226148, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1786600, Length=383, Percent_Identity=25.3263707571802, Blast_Score=90, Evalue=6e-19,
Organism=Escherichia coli, GI87081816, Length=241, Percent_Identity=30.2904564315353, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1788713, Length=243, Percent_Identity=31.2757201646091, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1790300, Length=342, Percent_Identity=27.1929824561404, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI145693157, Length=384, Percent_Identity=24.21875, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 76801; Mature: 76801

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEESITPPGELETLRGRVTDLARDNAHLKLINRMLLSLTSASGLENVVEQILRTLMETI
CCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GAFNLLVYYLVDGRWHCRDLFGSAREMESPDTPLVAACVRERIFQREQQDAREFLPGDSR
HHHHHHHHHHCCCCCHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PENWAFPLLVQQRLVGVVVMEGMIIAHDSIRIQLQPFFVYAALMLGNEISNYSVLEQTHQ
CCCCCHHHHHHHHHHHHHHHCCEEEEECCEEEEEHHHHHHHHHHHCCCCCCHHHHHHHHH
QLLQTHQALERETTARQEAEKLYRMLFEQSPDGIMLIDPESLRTLRCNHAAHRMLGYSLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHCCCHH
EFAALAIPDVAAQDDRNEVARRVRIALERGDHTFEARLCAKGGEFRDVLVTMRMMTTAGR
HHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEHHHHHCCCCHHHHHHHHHHHHHCCC
PLLHTICRDITDTKKMEQDLFKNQKMESIGLLAGGIAHDFNNLLAAIMGNISLASMLLQP
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
GSRSVSLLAESEKACLRARDLTLQLLTFSKGGAPVRRLASVEQIVRESASFVVRGSGTFC
CCCCEEHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEECCCCEE
NFHVANGLWQAEIDEGQISQVIHNLVINAVQAMPHGGVITITCSNVAAVTEGEADLVRID
EEEECCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCEEEEE
IEDQGEGITPEVLPRIFDPYFTTKRQGSGLGLASSYSIIRNHGGYIEVNSPPGKGAIFSI
ECCCCCCCCHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCEEEE
FLPATVATVLPPSVEPHQILTRPCKILVMDDEEMLRDVITSMLNMLGHRVETACDGKETL
EHHHHHHHHCCCCCCHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
TRYQRARDSRDPFDAVILDLTVPGGMGGRETMARLREIDPEVKGIVSSGYASDMALPDFR
HHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCC
SHGFCTILSKPYSMQDLIRVLEELFTQDAPT
CCCEEEEECCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNEESITPPGELETLRGRVTDLARDNAHLKLINRMLLSLTSASGLENVVEQILRTLMETI
CCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GAFNLLVYYLVDGRWHCRDLFGSAREMESPDTPLVAACVRERIFQREQQDAREFLPGDSR
HHHHHHHHHHCCCCCHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PENWAFPLLVQQRLVGVVVMEGMIIAHDSIRIQLQPFFVYAALMLGNEISNYSVLEQTHQ
CCCCCHHHHHHHHHHHHHHHCCEEEEECCEEEEEHHHHHHHHHHHCCCCCCHHHHHHHHH
QLLQTHQALERETTARQEAEKLYRMLFEQSPDGIMLIDPESLRTLRCNHAAHRMLGYSLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHCCCHH
EFAALAIPDVAAQDDRNEVARRVRIALERGDHTFEARLCAKGGEFRDVLVTMRMMTTAGR
HHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEHHHHHCCCCHHHHHHHHHHHHHCCC
PLLHTICRDITDTKKMEQDLFKNQKMESIGLLAGGIAHDFNNLLAAIMGNISLASMLLQP
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
GSRSVSLLAESEKACLRARDLTLQLLTFSKGGAPVRRLASVEQIVRESASFVVRGSGTFC
CCCCEEHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEECCCCEE
NFHVANGLWQAEIDEGQISQVIHNLVINAVQAMPHGGVITITCSNVAAVTEGEADLVRID
EEEECCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCEEEEE
IEDQGEGITPEVLPRIFDPYFTTKRQGSGLGLASSYSIIRNHGGYIEVNSPPGKGAIFSI
ECCCCCCCCHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCEEEE
FLPATVATVLPPSVEPHQILTRPCKILVMDDEEMLRDVITSMLNMLGHRVETACDGKETL
EHHHHHHHHCCCCCCHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
TRYQRARDSRDPFDAVILDLTVPGGMGGRETMARLREIDPEVKGIVSSGYASDMALPDFR
HHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCC
SHGFCTILSKPYSMQDLIRVLEELFTQDAPT
CCCEEEEECCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA