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The map label for this gene is fcbD [H]

Identifier: 118579844

GI number: 118579844

Start: 1517306

End: 1518091

Strand: Reverse

Name: fcbD [H]

Synonym: Ppro_1420

Alternate gene names: 118579844

Gene position: 1518091-1517306 (Counterclockwise)

Preceding gene: 118579845

Following gene: 118579843

Centisome position: 37.88

GC content: 61.83

Gene sequence:

>786_bases
ATGATGCCCATGCCTGAGGTCAGCGTGATCATACCCTGCTACAACCAGGGACAGTACCTGCACGAGGCGATTGACTCGGT
GCTGGGGCAGACCTTCAGCGACCTGGAAATCATCGTGGTAGATGACGGCTCCAGTGATCCGGCGACCCGGGAGGTCCTGG
ACGCCCTGAATCGAACGGCCACCAGACTGCTGCGGCGTAAAAACGGCGGCCTGGCCGCGGCTCGTAACAGCGGCATCAAT
GCGGCACATGGACGCTACATCCTCCCCCTGGACTGCGACGACCGCATCGCTCCGGATTACATCAGGCAGGCCCTAGCTGC
ATTTGAATCCGACCCGCTGTGCGGCATCGTCTACTGCCGGGCCGAAAAGTTCGGGGCCGAGCAGGGGACCTGGCGGCTCC
CCCCTTTCAGCAGGCTCCGCATGGGGCTGGGTAATGTGATCTTCTGTTCCGCGCTCTACCAGAAGAGCGACTGGCAGAGG
GTGGGGGGGTACGACGAAAACCTGCAACGGGGGTGGGAGGACTGGGACTTCTGGCTGGCGCTCCTGGAGCTGGGGCTCAC
CGTGCACTGCCTGCCATACGTCGGATTCCACTACCGCAAGAGCGAAAGCTCCATGGCCAGCTCCATGGATCCCGTGCTGA
AGGCAAACCTGCACCGACAGCTGATGCATAAACACCCTGACTTCTTCGGCCTCCTTTCCCGTACGCCACAGCCCCTGCTG
GAGATCTATTACCGCATGGCAGGGAGCGGAATCTATCGGCGCATCAAACGAAGTGGGGGACGCTGA

Upstream 100 bases:

>100_bases
CTTGAAACGATGTCCCAGGCCGCACATGAGTATGCCGCCGCCCATTTTTCATCGGCCCGTTTCTGTGAAGCATACCGCCG
GATTCTGGCGCCTGGCGGAT

Downstream 100 bases:

>100_bases
GCCATGAAGATCGTATTCCTGGCCCCCTTCGGCATCCGCCCCAAGGGAACCCTTCTGGCACGCATGCTTCCGTTGGCAAT
GGCCCTGAAAAAAGCCGGCC

Product: glycosyl transferase family protein

Products: NA

Alternate protein names: CS; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase; UDP-GalNAc transferase; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase; UDP-GlcUA transferase [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MMPMPEVSVIIPCYNQGQYLHEAIDSVLGQTFSDLEIIVVDDGSSDPATREVLDALNRTATRLLRRKNGGLAAARNSGIN
AAHGRYILPLDCDDRIAPDYIRQALAAFESDPLCGIVYCRAEKFGAEQGTWRLPPFSRLRMGLGNVIFCSALYQKSDWQR
VGGYDENLQRGWEDWDFWLALLELGLTVHCLPYVGFHYRKSESSMASSMDPVLKANLHRQLMHKHPDFFGLLSRTPQPLL
EIYYRMAGSGIYRRIKRSGGR

Sequences:

>Translated_261_residues
MMPMPEVSVIIPCYNQGQYLHEAIDSVLGQTFSDLEIIVVDDGSSDPATREVLDALNRTATRLLRRKNGGLAAARNSGIN
AAHGRYILPLDCDDRIAPDYIRQALAAFESDPLCGIVYCRAEKFGAEQGTWRLPPFSRLRMGLGNVIFCSALYQKSDWQR
VGGYDENLQRGWEDWDFWLALLELGLTVHCLPYVGFHYRKSESSMASSMDPVLKANLHRQLMHKHPDFFGLLSRTPQPLL
EIYYRMAGSGIYRRIKRSGGR
>Mature_261_residues
MMPMPEVSVIIPCYNQGQYLHEAIDSVLGQTFSDLEIIVVDDGSSDPATREVLDALNRTATRLLRRKNGGLAAARNSGIN
AAHGRYILPLDCDDRIAPDYIRQALAAFESDPLCGIVYCRAEKFGAEQGTWRLPPFSRLRMGLGNVIFCSALYQKSDWQR
VGGYDENLQRGWEDWDFWLALLELGLTVHCLPYVGFHYRKSESSMASSMDPVLKANLHRQLMHKHPDFFGLLSRTPQPLL
EIYYRMAGSGIYRRIKRSGGR

Specific function: Catalyzes the polymerization of chondroitin, a polysaccharide composed of a repeating disaccharide of N- acetylgalactosamine (GalNAc) and glucuronic acid (GlcUA) units. Each unit has the composition in beta-(1->4)-GlcUA-beta-(1->3)- GalNAc [H]

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family. CS/HAS subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790044, Length=165, Percent_Identity=33.9393939393939, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787259, Length=110, Percent_Identity=37.2727272727273, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: =2.4.1.175; =2.4.1.226 [H]

Molecular weight: Translated: 29530; Mature: 29530

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPMPEVSVIIPCYNQGQYLHEAIDSVLGQTFSDLEIIVVDDGSSDPATREVLDALNRTA
CCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
TRLLRRKNGGLAAARNSGINAAHGRYILPLDCDDRIAPDYIRQALAAFESDPLCGIVYCR
HHHHHHCCCCEEECCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEE
AEKFGAEQGTWRLPPFSRLRMGLGNVIFCSALYQKSDWQRVGGYDENLQRGWEDWDFWLA
HHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCHHHCCCCCHHHHCCCCHHHHHHH
LLELGLTVHCLPYVGFHYRKSESSMASSMDPVLKANLHRQLMHKHPDFFGLLSRTPQPLL
HHHHCCHHEEHHHHCCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHH
EIYYRMAGSGIYRRIKRSGGR
HHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MMPMPEVSVIIPCYNQGQYLHEAIDSVLGQTFSDLEIIVVDDGSSDPATREVLDALNRTA
CCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
TRLLRRKNGGLAAARNSGINAAHGRYILPLDCDDRIAPDYIRQALAAFESDPLCGIVYCR
HHHHHHCCCCEEECCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEE
AEKFGAEQGTWRLPPFSRLRMGLGNVIFCSALYQKSDWQRVGGYDENLQRGWEDWDFWLA
HHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCHHHCCCCCHHHHCCCCHHHHHHH
LLELGLTVHCLPYVGFHYRKSESSMASSMDPVLKANLHRQLMHKHPDFFGLLSRTPQPLL
HHHHCCHHEEHHHHCCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHH
EIYYRMAGSGIYRRIKRSGGR
HHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10818104; 11230405; 11248100 [H]