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The map label for this gene is hrcA [H]

Identifier: 118579830

GI number: 118579830

Start: 1498727

End: 1499758

Strand: Reverse

Name: hrcA [H]

Synonym: Ppro_1406

Alternate gene names: 118579830

Gene position: 1499758-1498727 (Counterclockwise)

Preceding gene: 118579833

Following gene: 118579829

Centisome position: 37.42

GC content: 59.79

Gene sequence:

>1032_bases
ATGGATGTGAAGCTCTCACCAAGAAGCAGACAGATACTCGAGGCCATCGTCGAAGACTATATCGCGACAGCCGAACCGGT
GGGCAGCAGCGCCGTGGCCCGCCGACACGCCATGACGCTCTCACCGGCAACGGTCCGCAACGTCATGGCCAATCTGGAGG
AACTCGGGCTGTTGACCTCGCCCCACACCTCCGCGGGAAGAATCCCCACCGAAAAGGCCTACCGTTTCTACGTAGATTCA
CTGGTGGCGTTGCGCAAGGTGACCCGCGAAGAGAAGAAACAGATCATCCACAGCTGTCGCCGGTCCGGCGCGGGACTGAC
CGAGATCCTTAAGGAAACCAGCCGCGCCCTCTCGTCCCTGTCCAACTACATGGGCATCGTGGTGGCCCCCAGCATAACCT
CCGACGTGTTCCGCTACATCGAATTCATCCACCTGGGACCCCGCCGGGTGCTGGCCATCCTTGTCTCCAGGAACGGATCG
GTGCAAAACAGGCTGGTGGAAACGGATGAGGAAATTTCTCCGGACGACCTGGTAAAAATGGGCAACTACCTGAACGAACT
GATGCAGGGGCTGACCATCTCCCAGGCCAGGGAACGGATCCTGGAAGAAATGAAAAAGGAAAAGACCCAGTACGACCACC
TGCTCTCCCAGGCACTGCGCATCAGCAAGCAGGCGGTGAGCGTGGAACGAGACGAAATATTCCTGGAGGGGCAGGCCCGC
ATCCTGGACCAACCGGAGTTCAGCGATGTAACCAGAATGAGGGACATTTTCCGGGCCTTCGAGGAAAAGGGGCGCCTGCT
GCAGCTGCTCGGCCGCTGCATGTCCGCCGAGGGTGTGCGCATTTTCATCGGATCCGAAGCCCCGCTCAGCCAGACCGCCG
GCGTCAGCTTGATCACCTCGCGATTCGTCACCAGCAGCAACGCCGTGGGGATGCTGGGAATCATCGGCCCCACCCGCATG
GGTTATTCCAGCGTCATCCCCATCGTCGACTATACAGCCCGCCTGTTGAGCCGTTTCCTGAACAACGACTGA

Upstream 100 bases:

>100_bases
CAGACCGGCAAATCCCCTTGACAAATCATAGGTCACTGATTAAATTCAGAAGGAAATTAGCACTCTCCAGTCATGAGTGC
TATTTTTTTGAGGTCATGGA

Downstream 100 bases:

>100_bases
CCGCCAGGACATTCGCATCAAAAATGAAACGCACAAAAAGGACTCACTGAACCATGAAAAAGCATGTAACAGAAGAACAG
AAAACTTCCGCCGCACCCGA

Product: heat-inducible transcription repressor HrcA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MDVKLSPRSRQILEAIVEDYIATAEPVGSSAVARRHAMTLSPATVRNVMANLEELGLLTSPHTSAGRIPTEKAYRFYVDS
LVALRKVTREEKKQIIHSCRRSGAGLTEILKETSRALSSLSNYMGIVVAPSITSDVFRYIEFIHLGPRRVLAILVSRNGS
VQNRLVETDEEISPDDLVKMGNYLNELMQGLTISQARERILEEMKKEKTQYDHLLSQALRISKQAVSVERDEIFLEGQAR
ILDQPEFSDVTRMRDIFRAFEEKGRLLQLLGRCMSAEGVRIFIGSEAPLSQTAGVSLITSRFVTSSNAVGMLGIIGPTRM
GYSSVIPIVDYTARLLSRFLNND

Sequences:

>Translated_343_residues
MDVKLSPRSRQILEAIVEDYIATAEPVGSSAVARRHAMTLSPATVRNVMANLEELGLLTSPHTSAGRIPTEKAYRFYVDS
LVALRKVTREEKKQIIHSCRRSGAGLTEILKETSRALSSLSNYMGIVVAPSITSDVFRYIEFIHLGPRRVLAILVSRNGS
VQNRLVETDEEISPDDLVKMGNYLNELMQGLTISQARERILEEMKKEKTQYDHLLSQALRISKQAVSVERDEIFLEGQAR
ILDQPEFSDVTRMRDIFRAFEEKGRLLQLLGRCMSAEGVRIFIGSEAPLSQTAGVSLITSRFVTSSNAVGMLGIIGPTRM
GYSSVIPIVDYTARLLSRFLNND
>Mature_343_residues
MDVKLSPRSRQILEAIVEDYIATAEPVGSSAVARRHAMTLSPATVRNVMANLEELGLLTSPHTSAGRIPTEKAYRFYVDS
LVALRKVTREEKKQIIHSCRRSGAGLTEILKETSRALSSLSNYMGIVVAPSITSDVFRYIEFIHLGPRRVLAILVSRNGS
VQNRLVETDEEISPDDLVKMGNYLNELMQGLTISQARERILEEMKKEKTQYDHLLSQALRISKQAVSVERDEIFLEGQAR
ILDQPEFSDVTRMRDIFRAFEEKGRLLQLLGRCMSAEGVRIFIGSEAPLSQTAGVSLITSRFVTSSNAVGMLGIIGPTRM
GYSSVIPIVDYTARLLSRFLNND

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005104
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03444 DUF293; PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 38278; Mature: 38278

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVKLSPRSRQILEAIVEDYIATAEPVGSSAVARRHAMTLSPATVRNVMANLEELGLLTS
CCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
PHTSAGRIPTEKAYRFYVDSLVALRKVTREEKKQIIHSCRRSGAGLTEILKETSRALSSL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
SNYMGIVVAPSITSDVFRYIEFIHLGPRRVLAILVSRNGSVQNRLVETDEEISPDDLVKM
HHHCCEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHH
GNYLNELMQGLTISQARERILEEMKKEKTQYDHLLSQALRISKQAVSVERDEIFLEGQAR
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHH
ILDQPEFSDVTRMRDIFRAFEEKGRLLQLLGRCMSAEGVRIFIGSEAPLSQTAGVSLITS
HCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCEEEEECCCCCCCHHCCHHHHHH
RFVTSSNAVGMLGIIGPTRMGYSSVIPIVDYTARLLSRFLNND
HHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDVKLSPRSRQILEAIVEDYIATAEPVGSSAVARRHAMTLSPATVRNVMANLEELGLLTS
CCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
PHTSAGRIPTEKAYRFYVDSLVALRKVTREEKKQIIHSCRRSGAGLTEILKETSRALSSL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
SNYMGIVVAPSITSDVFRYIEFIHLGPRRVLAILVSRNGSVQNRLVETDEEISPDDLVKM
HHHCCEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHH
GNYLNELMQGLTISQARERILEEMKKEKTQYDHLLSQALRISKQAVSVERDEIFLEGQAR
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHH
ILDQPEFSDVTRMRDIFRAFEEKGRLLQLLGRCMSAEGVRIFIGSEAPLSQTAGVSLITS
HCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCEEEEECCCCCCCHHCCHHHHHH
RFVTSSNAVGMLGIIGPTRMGYSSVIPIVDYTARLLSRFLNND
HHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA