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The map label for this gene is aroA

Identifier: 118579775

GI number: 118579775

Start: 1428909

End: 1430204

Strand: Direct

Name: aroA

Synonym: Ppro_1347

Alternate gene names: 118579775

Gene position: 1428909-1430204 (Clockwise)

Preceding gene: 118579774

Following gene: 118579776

Centisome position: 35.65

GC content: 64.27

Gene sequence:

>1296_bases
GTGAATTCCATCAGCATCACTCCGGGGTCATCACTGAAGGGGGAACTGGTCGTTCCCGGCGACAAATCCATCTCCCACCG
CTCAATCATGCTGGGCGCAATCGCCAATGGCGTAACCACCGTACGCGGCTTTTTGCGCGGTGAAGACAACATGGCTACCA
TGGCTGCTTTCCGTGCCATGGGGGTGCGCATCGACGACGATGGCCACCTGCTGTCCATTCACGGCAGGGGGTTGCATGGT
CTGGAGGAGCCGGGGGACGTGCTCGACTGCGGCAACTCCGGCACATCCATGCGGCTTTTGACCGGCCTCCTGGCCGGCCA
GAACTTCTTTTCCGTGCTCAGCGGTGACCAGTACCTGCGCAAGCGCCCCATGAAACGGGTCGTGGAGCCGCTCTCCCGCA
TGGGCGCCCGCATACTGGGGCGCGCCGGGGGAAACCTGGCGCCACTTGCCATCAGCGGCGGAACCCTGAATGCCATCGGC
TACGAGTCTCCGGTGTCCAGCGCCCAGATCAAGTCGGCCATCATGCTGGCCGGCCTGTACGCCGATGGCGACACCTCGGT
GCGCGAACCGAGTCTCTCCCGCGATCACTCCGAGCGGATGTTCGCCCTGTTCGGGGCGTCTCTGGAAACCTTCCACAACG
GCGTGACGGTCAAGGGAGGGATCGAACTGCATGCGCAGGAAATCCACGTTCCCGGTGACATCTCCTCGGCGGCGTTCTTT
ATCGTTGCCGCGCTGATCACGCCGGATTCCGAGCTGTTGATCCGCAACGTGGGGGTCAACCCGACCCGCACCGGCATCAT
CGACGTGCTGCGCTCCATGGGCGGAAGCATAGAACTGGTGGATGAACGCGAGGTTTCCGCCGAACCGGTGGCCGATATCC
TGGTGCGCTCCTCCCGCCTCAAGGGGGTGCGCATCGAGGGGCAGACGGTGCCGCGCGCCATCGACGAGTTTCCCGCCATC
TGCGTGGCCGCCGCCTGCGCCGAAGGGACCACCTCCATCCGCGATGCCCGCGAGTTGCGGGTCAAGGAGACCGACCGCAT
CAGCGCCATGGCGGTGAATCTGCGAACCCTGGGGGTGACGGTGGACGAGTGCGACGAGGGGATGGACATCACCGGCGTGG
AGCGTCTGGGCGGAGGCGTGGCCGAAAGCTTTGGCGACCATCGCATCGCCATGTCCCTGTCCGTGGCCGGCCTGGTGTCT
GCGGACGCTGTCAGGGTGAACGATATCGACTGCGTATCGACCTCCTTTCCCAACTTCTTCTCCCTGCTGGAACGCTTTCG
TACGGGTGCTCCATGA

Upstream 100 bases:

>100_bases
TCCCCGGGACTGGCCGAATTTTTTACCATCGCCAAGCAGTTTCGCGATGGTATCCTCTGAACCAAATTCTGTGCAATTGC
ATACCATGACTGGAGTATTC

Downstream 100 bases:

>100_bases
ACCGGCAGCCACGAGGACTGGTTATCGCCATCGACGGCCCTTCCGGGGCCGGCAAGAGCACCATTGCACGCCTTCTGGCC
AAGCGGCTCGGTTATCTGCA

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MNSISITPGSSLKGELVVPGDKSISHRSIMLGAIANGVTTVRGFLRGEDNMATMAAFRAMGVRIDDDGHLLSIHGRGLHG
LEEPGDVLDCGNSGTSMRLLTGLLAGQNFFSVLSGDQYLRKRPMKRVVEPLSRMGARILGRAGGNLAPLAISGGTLNAIG
YESPVSSAQIKSAIMLAGLYADGDTSVREPSLSRDHSERMFALFGASLETFHNGVTVKGGIELHAQEIHVPGDISSAAFF
IVAALITPDSELLIRNVGVNPTRTGIIDVLRSMGGSIELVDEREVSAEPVADILVRSSRLKGVRIEGQTVPRAIDEFPAI
CVAAACAEGTTSIRDARELRVKETDRISAMAVNLRTLGVTVDECDEGMDITGVERLGGGVAESFGDHRIAMSLSVAGLVS
ADAVRVNDIDCVSTSFPNFFSLLERFRTGAP

Sequences:

>Translated_431_residues
MNSISITPGSSLKGELVVPGDKSISHRSIMLGAIANGVTTVRGFLRGEDNMATMAAFRAMGVRIDDDGHLLSIHGRGLHG
LEEPGDVLDCGNSGTSMRLLTGLLAGQNFFSVLSGDQYLRKRPMKRVVEPLSRMGARILGRAGGNLAPLAISGGTLNAIG
YESPVSSAQIKSAIMLAGLYADGDTSVREPSLSRDHSERMFALFGASLETFHNGVTVKGGIELHAQEIHVPGDISSAAFF
IVAALITPDSELLIRNVGVNPTRTGIIDVLRSMGGSIELVDEREVSAEPVADILVRSSRLKGVRIEGQTVPRAIDEFPAI
CVAAACAEGTTSIRDARELRVKETDRISAMAVNLRTLGVTVDECDEGMDITGVERLGGGVAESFGDHRIAMSLSVAGLVS
ADAVRVNDIDCVSTSFPNFFSLLERFRTGAP
>Mature_431_residues
MNSISITPGSSLKGELVVPGDKSISHRSIMLGAIANGVTTVRGFLRGEDNMATMAAFRAMGVRIDDDGHLLSIHGRGLHG
LEEPGDVLDCGNSGTSMRLLTGLLAGQNFFSVLSGDQYLRKRPMKRVVEPLSRMGARILGRAGGNLAPLAISGGTLNAIG
YESPVSSAQIKSAIMLAGLYADGDTSVREPSLSRDHSERMFALFGASLETFHNGVTVKGGIELHAQEIHVPGDISSAAFF
IVAALITPDSELLIRNVGVNPTRTGIIDVLRSMGGSIELVDEREVSAEPVADILVRSSRLKGVRIEGQTVPRAIDEFPAI
CVAAACAEGTTSIRDARELRVKETDRISAMAVNLRTLGVTVDECDEGMDITGVERLGGGVAESFGDHRIAMSLSVAGLVS
ADAVRVNDIDCVSTSFPNFFSLLERFRTGAP

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=446, Percent_Identity=31.390134529148, Blast_Score=155, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6320332, Length=461, Percent_Identity=26.8980477223427, Blast_Score=120, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_PELPD (A1ANP7)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_901025.1
- ProteinModelPortal:   A1ANP7
- SMR:   A1ANP7
- STRING:   A1ANP7
- GeneID:   4573834
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_1347
- eggNOG:   COG0128
- HOGENOM:   HBG646626
- OMA:   LSRNHTE
- PhylomeDB:   A1ANP7
- ProtClustDB:   PRK02427
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 45558; Mature: 45558

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSISITPGSSLKGELVVPGDKSISHRSIMLGAIANGVTTVRGFLRGEDNMATMAAFRAM
CCCEECCCCCCCCCCEEECCCCCCCHHHEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
GVRIDDDGHLLSIHGRGLHGLEEPGDVLDCGNSGTSMRLLTGLLAGQNFFSVLSGDQYLR
CCEECCCCCEEEEECCCCCCCCCCCCEEECCCCCCHHHHHHHHHHCCHHHHHHCCCHHHH
KRPMKRVVEPLSRMGARILGRAGGNLAPLAISGGTLNAIGYESPVSSAQIKSAIMLAGLY
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEECCCCCCCCHHHHHHHHHEEEEE
ADGDTSVREPSLSRDHSERMFALFGASLETFHNGVTVKGGIELHAQEIHVPGDISSAAFF
ECCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHCCEEEECCEEEEEEEEECCCCCHHHHHH
IVAALITPDSELLIRNVGVNPTRTGIIDVLRSMGGSIELVDEREVSAEPVADILVRSSRL
HHHHHHCCCHHHEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCC
KGVRIEGQTVPRAIDEFPAICVAAACAEGTTSIRDARELRVKETDRISAMAVNLRTLGVT
CEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEEEEEEEEEE
VDECDEGMDITGVERLGGGVAESFGDHRIAMSLSVAGLVSADAVRVNDIDCVSTSFPNFF
HHHHCCCCCCCCHHHHCCHHHHHCCCCEEEEEEEEHHHEECCEEEECCCCCCCCCCHHHH
SLLERFRTGAP
HHHHHHHCCCC
>Mature Secondary Structure
MNSISITPGSSLKGELVVPGDKSISHRSIMLGAIANGVTTVRGFLRGEDNMATMAAFRAM
CCCEECCCCCCCCCCEEECCCCCCCHHHEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
GVRIDDDGHLLSIHGRGLHGLEEPGDVLDCGNSGTSMRLLTGLLAGQNFFSVLSGDQYLR
CCEECCCCCEEEEECCCCCCCCCCCCEEECCCCCCHHHHHHHHHHCCHHHHHHCCCHHHH
KRPMKRVVEPLSRMGARILGRAGGNLAPLAISGGTLNAIGYESPVSSAQIKSAIMLAGLY
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEECCCCCCCCHHHHHHHHHEEEEE
ADGDTSVREPSLSRDHSERMFALFGASLETFHNGVTVKGGIELHAQEIHVPGDISSAAFF
ECCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHCCEEEECCEEEEEEEEECCCCCHHHHHH
IVAALITPDSELLIRNVGVNPTRTGIIDVLRSMGGSIELVDEREVSAEPVADILVRSSRL
HHHHHHCCCHHHEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCC
KGVRIEGQTVPRAIDEFPAICVAAACAEGTTSIRDARELRVKETDRISAMAVNLRTLGVT
CEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEEEEEEEEEE
VDECDEGMDITGVERLGGGVAESFGDHRIAMSLSVAGLVSADAVRVNDIDCVSTSFPNFF
HHHHCCCCCCCCHHHHCCHHHHHCCCCEEEEEEEEHHHEECCEEEECCCCCCCCCCHHHH
SLLERFRTGAP
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA