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The map label for this gene is pyc [H]

Identifier: 118579764

GI number: 118579764

Start: 1411949

End: 1415395

Strand: Direct

Name: pyc [H]

Synonym: Ppro_1336

Alternate gene names: 118579764

Gene position: 1411949-1415395 (Clockwise)

Preceding gene: 118579760

Following gene: 118579766

Centisome position: 35.23

GC content: 62.34

Gene sequence:

>3447_bases
ATGCAGAAGAGGAAGTTTAAAAAAATCATGGCAGCCAACCGCGGCGAGATTTCCGTCCGCATCTTCCGCGCCTGCGCCGA
GCTGGGCATCAGGATGGTGGCCATTTATTCCGAAGAGGACAAACTGTCGCTGCATCGTTACAAGGCTGATGAGGCCTACC
TGATCGGCAAGGGCAAGGCGCCCGTGGAGGCCTACCTGGGCATCGACGAGATCATCGCCCTGGCGCTGAAGGTCGGTGTG
GAGGCGATCCACCCCGGCTATGGATTTCTGTCCGAGAACGCCGAGTTTGCCGAGAAGTGCGAGGCCAACGGCATCGTCTT
CATCGGTCCCACGGGCGAGATGCAACGCGCCCTGGGGGATAAGGTTGCCGGCCGCAAGATGGCCACGGCTGCCGGTGTCA
ATGTGGTGCCTGGCACCGAGGATCCCATCGAGCGGGAAGAGGATGCCCTGAAGTTCGCCAAGCAGTACGGTTACCCGATC
ATCGTCAAGGCGGCGGCCGGCGGCGGCGGTCGCGGCATGCGTGTGGCCCACAACCAGAAAGAGTTGCTGGAAGGCTTGGT
GGCGGCCGGGAGCGAGGCCAAGGCTGCCTTCGGCAACGCGGCCGTGTTCCTGGAACGCTATCTGGAGAACCCCAAGCATA
TCGAGGTGCAGGTGCTGGGGGACAACTACGGCAACCTGGTGCATTTCTTCGAGCGTGACTGCTCGGTGCAACGCCGCCAC
CAGAAGGTGGTGGAGTTCGCGCCTTCCCTCTGCATCACCCCCGAACTGCGCGAGGAACTGTGCGACGCTGCGCTGAAGAT
CGCCCGGCAGGTCAACTACCGCAATGCCGGTACGGTGGAGTTCCTGGTGGATCAGCAGGGGCGTTACTACTTCATGGAGA
TGAACCCCCGCATCCAGGTGGAGCATACCGTGACCGAGATGATCACCGGCCGCAACCTGGTGCAGAACCAGATCCTGGTG
GCCGGCGGTTACGCCCTCTCTGACCCGGAGATCAATATCCCTTCCCAGGGCGCCATCAACATGCGCGGCTATGCCATCCA
GTGCCGCGTGACCACCGAAGATCCGGCCAACAACTTCGCCCCTGATTTCGGCATGCTGACCACCTACCGCTCTGCTGCCG
GCTGCGGGGTGCGTCTGGACGCCGGCAACGCCACCACCGGCGCCAGGATCACCCCCCACTACGATTCGCTGCTGGTCAAG
GTGGGCACCTGGGGACTTACCTTCCCGGAGGCGGCCCATATCATGGACCGGGCCCTGCGGGAGTTCAGGATCCGCGGGGT
CAAGACCAACATCGCCTTCCTGGAGAACGTGGTTACCCACCCGGTGTTTCTGGAGGGGAAGTGCGACACCTCCTTCATTG
ACAAGCATCCCGAGCTTCTGGTCTTCGAGGAGCGGAAGGACCGTGCCTCCAAACTGCTCAATTACCTGGGCGAGGTGGTT
GTCAATGGTATTCCCGGCATCACCGAGCGCATGAAGTCGTCCCAACTTGCCGAAGCCAGGGTGCCCGAGGTGGATGTGCT
CTCCCCCCGCCCCCAGGGGACCCGCGACCTGTTCAGAAAGATGGGCGCCGAGGCATTCTGCACGTGGGTGCTGGAGCAGG
AACGGCTGTTTCTGACTGATACCTCCATGCGCGACGCCCACCAGTCCAACCTGGCCACCCGCGTGCGCAGCTATGACCTG
CTCAAGATCGCCGAGCCCACCTCCTACCTGGGGGCGGAGCTCTTCTCCCTTGAGTGCTGGGGAGGAGCGACCTTCGATGT
CTCCATGCGCTTCCTGAAGGAAGACCCCTGGCAACGGCTGCATGCCCTGTCGGAGAAAGTGCCCAATGTCCTCTTGCAGA
TGCTGCTGCGCGGCTCCAATGCCGTGGGCTACACCAACTACCCGGACAACGTGGTGGAACGCTTCGTCGATGAGGCGGCC
CGCTCAGGCATCGACGTCTTCCGCGTGTTCGACTCCCTCAACTGGACCACAGGCATGCAGGTGGCCATGGAGGCGGTGCG
CAAGACAGGCAAGATCTGCGAGGCGGCCATCTGCTACACCGGCGACATCACCGATCCCAAGCGTGACAAGTATCCGTTGG
AATACTACGTCAACCTGGCCAAGGAACTGGAAAAGATGGGCGCCCACATCCTGGCCATCAAGGACATGGCCGGCCTGCTC
AAGCCCTTTGCCGCCTACCGGCTGATCAAGGCGCTTAAGGAGAACATCGGCATCCCGGTGCATCTGCATACCCACGACAC
CTCCTCCAACGGCGGCGCCACCCTGCTCAAGGCCAGCGAGGCCGGGGTGGATATCGTGGATGCGGCCCTCTCCGCCCTGT
CCGGCCTGACCGCCCAGCCCAGCCTGAACGCCATCGCCTCGGCCTTGGAGGGGAGCGAGCGCGACCCGCTGGTCAACGGC
CGCGGCCTGCAGCAGCTGTCAAACTACTGGGAAACGGTGCGGGATTACTACGCCCCCTTCGAGTCCGGCCTCAAGGGAGG
CACGGCCGAGGTCTACGAGCATGAGATTCCGGGCGGACAGTACTCCAACTTCAAGCCGCAGGTTGCGGGCATGGGGCTCA
TCGACCGCTGGGAGGAGTGCAAGGAGATGTACCGCAAGGTGAACCTCCTGTTCGGCGACATCGTCAAGGTCACCCCCACC
TCCAAGGTTGTGGGGGACATGGCCATGTTCCTGGTCAAGAACAACATGCAGCCGGAGGATATCTACACCGCCAGGGAAGA
GCTGGCCTTCCCCGAATCGGTGGTCGGCATGTTCAAGGGGATGCTGGGACAGCCCCACCAGGGATGGCCTGCCGACCTGC
AGCGGATCATACTCAAGGGAGAGCAGCCGATCACCTGCCGTCCCGGCGAGCTCCTGCAGCCGATCGACTTCCAGGAGGAA
CGCCGCAAGCTGGAGGAAAAGCTGGGGCACCCGGTGGACGACAAGGCGCTGCTCTCCGCCATCCTCTATCCCAACGTGTA
CCCGGACTTCGACAAGCATCTCCAGAAGTATTCCGACACCTCGGTGATACCGACCCCGATCTTCTTCTACGGCCTTGAGC
CGGGGCAGGAGACCTCCCTGGACATCGAGCCGGGCAAGACCCTGATCATCGCCCTCAACGCCATCGGCCGCCTGCACGAT
GATGGCACCCGCGTGGTTTCCTTCTCCCTGAACGGCAATAACCGTTCGGTGATTATCCGCGACCGTTCGGTCACCAGCGG
CGTGTTCGTGCGCGACAAGGCCGACAGGGACAACCCCAGCCATATCGGCGCTCCCATGCCGGGCAAGGTGTTCAAGGTCA
ATGTCAAGCCGGGCTTCGAGGTCAAGGCCGGTGATGTGCTGATGGTAACCGAAGCCATGAAGATGGAGACCAACATCAAG
GCCAAAGTCGACGGCCGGGTGATGGAGGTCAAGTTCAAGGAAGGGGACAAGGTGGAGAAGGACGACCTGTTAATCGTCAT
GGGTTGA

Upstream 100 bases:

>100_bases
AGGTGTAACTATATAAAATAGCTTGTATCTTTTTTTGGCGATGGATTGTCGCCGCGTTTGCCGGACATAGCGATACTTAT
CAGGATCAGGAGGTCATTCA

Downstream 100 bases:

>100_bases
GCCCTGTCCTGCTCCTGCTCCCGTTGAAACAAGCCCCCCGATGCGCTGCCCCGGGGGGCTTTTTATGTCCGGGGTACAAC
AGGGAGGTGTCTCAGTTTCG

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1148; Mature: 1148

Protein sequence:

>1148_residues
MQKRKFKKIMAANRGEISVRIFRACAELGIRMVAIYSEEDKLSLHRYKADEAYLIGKGKAPVEAYLGIDEIIALALKVGV
EAIHPGYGFLSENAEFAEKCEANGIVFIGPTGEMQRALGDKVAGRKMATAAGVNVVPGTEDPIEREEDALKFAKQYGYPI
IVKAAAGGGGRGMRVAHNQKELLEGLVAAGSEAKAAFGNAAVFLERYLENPKHIEVQVLGDNYGNLVHFFERDCSVQRRH
QKVVEFAPSLCITPELREELCDAALKIARQVNYRNAGTVEFLVDQQGRYYFMEMNPRIQVEHTVTEMITGRNLVQNQILV
AGGYALSDPEINIPSQGAINMRGYAIQCRVTTEDPANNFAPDFGMLTTYRSAAGCGVRLDAGNATTGARITPHYDSLLVK
VGTWGLTFPEAAHIMDRALREFRIRGVKTNIAFLENVVTHPVFLEGKCDTSFIDKHPELLVFEERKDRASKLLNYLGEVV
VNGIPGITERMKSSQLAEARVPEVDVLSPRPQGTRDLFRKMGAEAFCTWVLEQERLFLTDTSMRDAHQSNLATRVRSYDL
LKIAEPTSYLGAELFSLECWGGATFDVSMRFLKEDPWQRLHALSEKVPNVLLQMLLRGSNAVGYTNYPDNVVERFVDEAA
RSGIDVFRVFDSLNWTTGMQVAMEAVRKTGKICEAAICYTGDITDPKRDKYPLEYYVNLAKELEKMGAHILAIKDMAGLL
KPFAAYRLIKALKENIGIPVHLHTHDTSSNGGATLLKASEAGVDIVDAALSALSGLTAQPSLNAIASALEGSERDPLVNG
RGLQQLSNYWETVRDYYAPFESGLKGGTAEVYEHEIPGGQYSNFKPQVAGMGLIDRWEECKEMYRKVNLLFGDIVKVTPT
SKVVGDMAMFLVKNNMQPEDIYTAREELAFPESVVGMFKGMLGQPHQGWPADLQRIILKGEQPITCRPGELLQPIDFQEE
RRKLEEKLGHPVDDKALLSAILYPNVYPDFDKHLQKYSDTSVIPTPIFFYGLEPGQETSLDIEPGKTLIIALNAIGRLHD
DGTRVVSFSLNGNNRSVIIRDRSVTSGVFVRDKADRDNPSHIGAPMPGKVFKVNVKPGFEVKAGDVLMVTEAMKMETNIK
AKVDGRVMEVKFKEGDKVEKDDLLIVMG

Sequences:

>Translated_1148_residues
MQKRKFKKIMAANRGEISVRIFRACAELGIRMVAIYSEEDKLSLHRYKADEAYLIGKGKAPVEAYLGIDEIIALALKVGV
EAIHPGYGFLSENAEFAEKCEANGIVFIGPTGEMQRALGDKVAGRKMATAAGVNVVPGTEDPIEREEDALKFAKQYGYPI
IVKAAAGGGGRGMRVAHNQKELLEGLVAAGSEAKAAFGNAAVFLERYLENPKHIEVQVLGDNYGNLVHFFERDCSVQRRH
QKVVEFAPSLCITPELREELCDAALKIARQVNYRNAGTVEFLVDQQGRYYFMEMNPRIQVEHTVTEMITGRNLVQNQILV
AGGYALSDPEINIPSQGAINMRGYAIQCRVTTEDPANNFAPDFGMLTTYRSAAGCGVRLDAGNATTGARITPHYDSLLVK
VGTWGLTFPEAAHIMDRALREFRIRGVKTNIAFLENVVTHPVFLEGKCDTSFIDKHPELLVFEERKDRASKLLNYLGEVV
VNGIPGITERMKSSQLAEARVPEVDVLSPRPQGTRDLFRKMGAEAFCTWVLEQERLFLTDTSMRDAHQSNLATRVRSYDL
LKIAEPTSYLGAELFSLECWGGATFDVSMRFLKEDPWQRLHALSEKVPNVLLQMLLRGSNAVGYTNYPDNVVERFVDEAA
RSGIDVFRVFDSLNWTTGMQVAMEAVRKTGKICEAAICYTGDITDPKRDKYPLEYYVNLAKELEKMGAHILAIKDMAGLL
KPFAAYRLIKALKENIGIPVHLHTHDTSSNGGATLLKASEAGVDIVDAALSALSGLTAQPSLNAIASALEGSERDPLVNG
RGLQQLSNYWETVRDYYAPFESGLKGGTAEVYEHEIPGGQYSNFKPQVAGMGLIDRWEECKEMYRKVNLLFGDIVKVTPT
SKVVGDMAMFLVKNNMQPEDIYTAREELAFPESVVGMFKGMLGQPHQGWPADLQRIILKGEQPITCRPGELLQPIDFQEE
RRKLEEKLGHPVDDKALLSAILYPNVYPDFDKHLQKYSDTSVIPTPIFFYGLEPGQETSLDIEPGKTLIIALNAIGRLHD
DGTRVVSFSLNGNNRSVIIRDRSVTSGVFVRDKADRDNPSHIGAPMPGKVFKVNVKPGFEVKAGDVLMVTEAMKMETNIK
AKVDGRVMEVKFKEGDKVEKDDLLIVMG
>Mature_1148_residues
MQKRKFKKIMAANRGEISVRIFRACAELGIRMVAIYSEEDKLSLHRYKADEAYLIGKGKAPVEAYLGIDEIIALALKVGV
EAIHPGYGFLSENAEFAEKCEANGIVFIGPTGEMQRALGDKVAGRKMATAAGVNVVPGTEDPIEREEDALKFAKQYGYPI
IVKAAAGGGGRGMRVAHNQKELLEGLVAAGSEAKAAFGNAAVFLERYLENPKHIEVQVLGDNYGNLVHFFERDCSVQRRH
QKVVEFAPSLCITPELREELCDAALKIARQVNYRNAGTVEFLVDQQGRYYFMEMNPRIQVEHTVTEMITGRNLVQNQILV
AGGYALSDPEINIPSQGAINMRGYAIQCRVTTEDPANNFAPDFGMLTTYRSAAGCGVRLDAGNATTGARITPHYDSLLVK
VGTWGLTFPEAAHIMDRALREFRIRGVKTNIAFLENVVTHPVFLEGKCDTSFIDKHPELLVFEERKDRASKLLNYLGEVV
VNGIPGITERMKSSQLAEARVPEVDVLSPRPQGTRDLFRKMGAEAFCTWVLEQERLFLTDTSMRDAHQSNLATRVRSYDL
LKIAEPTSYLGAELFSLECWGGATFDVSMRFLKEDPWQRLHALSEKVPNVLLQMLLRGSNAVGYTNYPDNVVERFVDEAA
RSGIDVFRVFDSLNWTTGMQVAMEAVRKTGKICEAAICYTGDITDPKRDKYPLEYYVNLAKELEKMGAHILAIKDMAGLL
KPFAAYRLIKALKENIGIPVHLHTHDTSSNGGATLLKASEAGVDIVDAALSALSGLTAQPSLNAIASALEGSERDPLVNG
RGLQQLSNYWETVRDYYAPFESGLKGGTAEVYEHEIPGGQYSNFKPQVAGMGLIDRWEECKEMYRKVNLLFGDIVKVTPT
SKVVGDMAMFLVKNNMQPEDIYTAREELAFPESVVGMFKGMLGQPHQGWPADLQRIILKGEQPITCRPGELLQPIDFQEE
RRKLEEKLGHPVDDKALLSAILYPNVYPDFDKHLQKYSDTSVIPTPIFFYGLEPGQETSLDIEPGKTLIIALNAIGRLHD
DGTRVVSFSLNGNNRSVIIRDRSVTSGVFVRDKADRDNPSHIGAPMPGKVFKVNVKPGFEVKAGDVLMVTEAMKMETNIK
AKVDGRVMEVKFKEGDKVEKDDLLIVMG

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1148, Percent_Identity=49.8257839721254, Blast_Score=1100, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1148, Percent_Identity=49.8257839721254, Blast_Score=1100, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1148, Percent_Identity=49.8257839721254, Blast_Score=1100, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=464, Percent_Identity=42.8879310344828, Blast_Score=386, Evalue=1e-107,
Organism=Homo sapiens, GI189095269, Length=459, Percent_Identity=44.0087145969499, Blast_Score=375, Evalue=1e-103,
Organism=Homo sapiens, GI65506442, Length=460, Percent_Identity=43.9130434782609, Blast_Score=374, Evalue=1e-103,
Organism=Homo sapiens, GI295821183, Length=460, Percent_Identity=43.9130434782609, Blast_Score=374, Evalue=1e-103,
Organism=Homo sapiens, GI38679960, Length=515, Percent_Identity=30.873786407767, Blast_Score=239, Evalue=1e-62,
Organism=Homo sapiens, GI38679977, Length=515, Percent_Identity=30.873786407767, Blast_Score=239, Evalue=1e-62,
Organism=Homo sapiens, GI38679967, Length=515, Percent_Identity=30.873786407767, Blast_Score=239, Evalue=1e-62,
Organism=Homo sapiens, GI38679971, Length=515, Percent_Identity=30.873786407767, Blast_Score=239, Evalue=1e-62,
Organism=Homo sapiens, GI38679974, Length=514, Percent_Identity=30.9338521400778, Blast_Score=239, Evalue=1e-62,
Organism=Homo sapiens, GI134142062, Length=506, Percent_Identity=30.6324110671937, Blast_Score=229, Evalue=1e-59,
Organism=Escherichia coli, GI1789654, Length=451, Percent_Identity=45.6762749445676, Blast_Score=359, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17562816, Length=1148, Percent_Identity=50.4355400696864, Blast_Score=1138, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987519, Length=461, Percent_Identity=43.8177874186551, Blast_Score=364, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17567343, Length=458, Percent_Identity=42.3580786026201, Blast_Score=349, Evalue=6e-96,
Organism=Caenorhabditis elegans, GI71997168, Length=439, Percent_Identity=29.3849658314351, Blast_Score=202, Evalue=8e-52,
Organism=Caenorhabditis elegans, GI71997163, Length=439, Percent_Identity=29.3849658314351, Blast_Score=202, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI133931226, Length=494, Percent_Identity=29.3522267206478, Blast_Score=192, Evalue=9e-49,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1154, Percent_Identity=48.786828422877, Blast_Score=1076, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1174, Percent_Identity=48.7223168654174, Blast_Score=1071, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=452, Percent_Identity=38.0530973451327, Blast_Score=317, Evalue=8e-87,
Organism=Saccharomyces cerevisiae, GI6324343, Length=510, Percent_Identity=30, Blast_Score=222, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6323863, Length=435, Percent_Identity=32.4137931034483, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24652212, Length=1152, Percent_Identity=50.1736111111111, Blast_Score=1124, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1152, Percent_Identity=50.1736111111111, Blast_Score=1124, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1152, Percent_Identity=50.1736111111111, Blast_Score=1124, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1152, Percent_Identity=50.1736111111111, Blast_Score=1124, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1152, Percent_Identity=50.1736111111111, Blast_Score=1124, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1168, Percent_Identity=49.7431506849315, Blast_Score=1115, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1168, Percent_Identity=49.7431506849315, Blast_Score=1115, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1168, Percent_Identity=49.7431506849315, Blast_Score=1115, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1168, Percent_Identity=49.7431506849315, Blast_Score=1115, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1168, Percent_Identity=49.7431506849315, Blast_Score=1115, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=489, Percent_Identity=39.6728016359918, Blast_Score=365, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24651759, Length=449, Percent_Identity=39.1982182628062, Blast_Score=326, Evalue=5e-89,
Organism=Drosophila melanogaster, GI24586458, Length=501, Percent_Identity=31.1377245508982, Blast_Score=233, Evalue=6e-61,
Organism=Drosophila melanogaster, GI161076407, Length=501, Percent_Identity=31.1377245508982, Blast_Score=233, Evalue=7e-61,
Organism=Drosophila melanogaster, GI24586460, Length=501, Percent_Identity=31.1377245508982, Blast_Score=233, Evalue=7e-61,
Organism=Drosophila melanogaster, GI161076409, Length=501, Percent_Identity=31.1377245508982, Blast_Score=233, Evalue=8e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 127258; Mature: 127258

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKRKFKKIMAANRGEISVRIFRACAELGIRMVAIYSEEDKLSLHRYKADEAYLIGKGKA
CCHHHHHHHHCCCCCCEEHHHHHHHHHCCEEEEEEECCCCCCCCEEECCCCEEEEECCCC
PVEAYLGIDEIIALALKVGVEAIHPGYGFLSENAEFAEKCEANGIVFIGPTGEMQRALGD
CHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEECCCHHHHHHHHH
KVAGRKMATAAGVNVVPGTEDPIEREEDALKFAKQYGYPIIVKAAAGGGGRGMRVAHNQK
HHCCCHHHHHCCCEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEECCCHH
ELLEGLVAAGSEAKAAFGNAAVFLERYLENPKHIEVQVLGDNYGNLVHFFERDCSVQRRH
HHHHHHHHCCCCHHHHHCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCHHHHHHH
QKVVEFAPSLCITPELREELCDAALKIARQVNYRNAGTVEFLVDQQGRYYFMEMNPRIQV
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEECCCCEEE
EHTVTEMITGRNLVQNQILVAGGYALSDPEINIPSQGAINMRGYAIQCRVTTEDPANNFA
HHHHHHHHHCCHHHHCCEEEECCEEECCCCCCCCCCCCEEECCEEEEEEEECCCCCCCCC
PDFGMLTTYRSAAGCGVRLDAGNATTGARITPHYDSLLVKVGTWGLTFPEAAHIMDRALR
CCCCHHHHHHHCCCCCEEEECCCCCCCCEECCCHHCEEEEECCCCCCCCHHHHHHHHHHH
EFRIRGVKTNIAFLENVVTHPVFLEGKCDTSFIDKHPELLVFEERKDRASKLLNYLGEVV
HHHHCCCCHHHHHHHHHHCCCEEEECCCCCHHHCCCCCEEEECCHHHHHHHHHHHHHHHH
VNGIPGITERMKSSQLAEARVPEVDVLSPRPQGTRDLFRKMGAEAFCTWVLEQERLFLTD
HCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHCCCCEEEEEC
TSMRDAHQSNLATRVRSYDLLKIAEPTSYLGAELFSLECWGGATFDVSMRFLKEDPWQRL
CCHHHHHHHHHHHHHHCCCEEEECCCHHHHCCCEEEEEECCCCCHHHHHHHHHCCHHHHH
HALSEKVPNVLLQMLLRGSNAVGYTNYPDNVVERFVDEAARSGIDVFRVFDSLNWTTGMQ
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHH
VAMEAVRKTGKICEAAICYTGDITDPKRDKYPLEYYVNLAKELEKMGAHILAIKDMAGLL
HHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHH
KPFAAYRLIKALKENIGIPVHLHTHDTSSNGGATLLKASEAGVDIVDAALSALSGLTAQP
HHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCC
SLNAIASALEGSERDPLVNGRGLQQLSNYWETVRDYYAPFESGLKGGTAEVYEHEIPGGQ
CHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHEECCCCCC
YSNFKPQVAGMGLIDRWEECKEMYRKVNLLFGDIVKVTPTSKVVGDMAMFLVKNNMQPED
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHCCCCHHH
IYTAREELAFPESVVGMFKGMLGQPHQGWPADLQRIILKGEQPITCRPGELLQPIDFQEE
HHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCCHHH
RRKLEEKLGHPVDDKALLSAILYPNVYPDFDKHLQKYSDTSVIPTPIFFYGLEPGQETSL
HHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCEE
DIEPGKTLIIALNAIGRLHDDGTRVVSFSLNGNNRSVIIRDRSVTSGVFVRDKADRDNPS
EECCCCEEEEEEEHHHCCCCCCCEEEEEEECCCCCEEEEECCCCCCCEEEECCCCCCCCC
HIGAPMPGKVFKVNVKPGFEVKAGDVLMVTEAMKMETNIKAKVDGRVMEVKFKEGDKVEK
CCCCCCCCCEEEEECCCCCEECCCCEEEEEHHHHHCCCCEEEECCEEEEEEECCCCCCCC
DDLLIVMG
CCEEEEEC
>Mature Secondary Structure
MQKRKFKKIMAANRGEISVRIFRACAELGIRMVAIYSEEDKLSLHRYKADEAYLIGKGKA
CCHHHHHHHHCCCCCCEEHHHHHHHHHCCEEEEEEECCCCCCCCEEECCCCEEEEECCCC
PVEAYLGIDEIIALALKVGVEAIHPGYGFLSENAEFAEKCEANGIVFIGPTGEMQRALGD
CHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEECCCHHHHHHHHH
KVAGRKMATAAGVNVVPGTEDPIEREEDALKFAKQYGYPIIVKAAAGGGGRGMRVAHNQK
HHCCCHHHHHCCCEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEECCCHH
ELLEGLVAAGSEAKAAFGNAAVFLERYLENPKHIEVQVLGDNYGNLVHFFERDCSVQRRH
HHHHHHHHCCCCHHHHHCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCHHHHHHH
QKVVEFAPSLCITPELREELCDAALKIARQVNYRNAGTVEFLVDQQGRYYFMEMNPRIQV
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEECCCCEEE
EHTVTEMITGRNLVQNQILVAGGYALSDPEINIPSQGAINMRGYAIQCRVTTEDPANNFA
HHHHHHHHHCCHHHHCCEEEECCEEECCCCCCCCCCCCEEECCEEEEEEEECCCCCCCCC
PDFGMLTTYRSAAGCGVRLDAGNATTGARITPHYDSLLVKVGTWGLTFPEAAHIMDRALR
CCCCHHHHHHHCCCCCEEEECCCCCCCCEECCCHHCEEEEECCCCCCCCHHHHHHHHHHH
EFRIRGVKTNIAFLENVVTHPVFLEGKCDTSFIDKHPELLVFEERKDRASKLLNYLGEVV
HHHHCCCCHHHHHHHHHHCCCEEEECCCCCHHHCCCCCEEEECCHHHHHHHHHHHHHHHH
VNGIPGITERMKSSQLAEARVPEVDVLSPRPQGTRDLFRKMGAEAFCTWVLEQERLFLTD
HCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHCCCCEEEEEC
TSMRDAHQSNLATRVRSYDLLKIAEPTSYLGAELFSLECWGGATFDVSMRFLKEDPWQRL
CCHHHHHHHHHHHHHHCCCEEEECCCHHHHCCCEEEEEECCCCCHHHHHHHHHCCHHHHH
HALSEKVPNVLLQMLLRGSNAVGYTNYPDNVVERFVDEAARSGIDVFRVFDSLNWTTGMQ
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHH
VAMEAVRKTGKICEAAICYTGDITDPKRDKYPLEYYVNLAKELEKMGAHILAIKDMAGLL
HHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHH
KPFAAYRLIKALKENIGIPVHLHTHDTSSNGGATLLKASEAGVDIVDAALSALSGLTAQP
HHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCC
SLNAIASALEGSERDPLVNGRGLQQLSNYWETVRDYYAPFESGLKGGTAEVYEHEIPGGQ
CHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHEECCCCCC
YSNFKPQVAGMGLIDRWEECKEMYRKVNLLFGDIVKVTPTSKVVGDMAMFLVKNNMQPED
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHCCCCHHH
IYTAREELAFPESVVGMFKGMLGQPHQGWPADLQRIILKGEQPITCRPGELLQPIDFQEE
HHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCCHHH
RRKLEEKLGHPVDDKALLSAILYPNVYPDFDKHLQKYSDTSVIPTPIFFYGLEPGQETSL
HHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCEE
DIEPGKTLIIALNAIGRLHDDGTRVVSFSLNGNNRSVIIRDRSVTSGVFVRDKADRDNPS
EECCCCEEEEEEEHHHCCCCCCCEEEEEEECCCCCEEEEECCCCCCCEEEECCCCCCCCC
HIGAPMPGKVFKVNVKPGFEVKAGDVLMVTEAMKMETNIKAKVDGRVMEVKFKEGDKVEK
CCCCCCCCCEEEEECCCCCEECCCCEEEEEHHHHHCCCCEEEECCEEEEEEECCCCCCCC
DDLLIVMG
CCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]