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The map label for this gene is hemN [H]

Identifier: 118579732

GI number: 118579732

Start: 1375411

End: 1376556

Strand: Reverse

Name: hemN [H]

Synonym: Ppro_1304

Alternate gene names: 118579732

Gene position: 1376556-1375411 (Counterclockwise)

Preceding gene: 118579740

Following gene: 118579731

Centisome position: 34.35

GC content: 64.31

Gene sequence:

>1146_bases
ATGTTCACCCGCCTCTACATCCATATCCCCTTCTGTCTGCACAAGTGCCCCTACTGCGCCTTCATCTCCCAGGAGGGCTC
CCCAGCCCGGCGGGAGGCATACGTGGAACTGTTGCAGGCCGAGATGCGCCTGGCCCATGCCGGGATTCCGTCCGGCCGCC
CCCTGGAGTCGGTCTACTTCGGCGGAGGAACTCCGTCCCTGCTGGAACCCGACCAGATCGGACGGATACTTTCCCTGGCC
GACACCCTGTTTAGCCTGTTGCCCCATGCCGAGATCACCCTGGAGGCCAACCCGGGCACCATCGACAGGGCGAAGCTGGC
GGGCTTCCGCCATTCAGGAGTCAACCGGCTCTCCCTGGGGGTGCAGTCCTTAGACGACCGCATGCTGGCCAGCCTGGGGC
GGATCCATTCGGCGGCCCAGGCAGAACAGGCCGTGAAGGCGGCCCGGGCGACCGGGTTCGCTAACATCGGCATCGACCTG
ATCCATGCCCTGCCGGGACAGACCATGGAGATGTGGCGCCACGACCTGGAGCGTGCCCTGGATCTGGCGCCGGAGCACCT
GTCGGTCTACGGCCTGACCATCGAGGAGGGCACCCCCTTCGCCCAACGCTACACCCATGACCGTGACCTGCCGGACGAAG
ACCTGTCCGCCGACATGTTCCTAGCCGCCGATGACCTGCTGGGCGCTGCCGGGTACGAGCATTACGAGATCGCCAACTAC
GCCCTCCCCGGCTTTCGTTCCCGACACAACAGCGGCTACTGGAGGCGCGACGGCTACCTGGGGCTGGGGGCCGGCGCCCA
CTCATTCCTGCGTGGCACCGGCCACGGCCTCCGCTTCGCCAACAGTAGCGACGTCGACGAGTATGCAGCCGCCATCACTC
GTGGCCAGTTACCCCGACAGGAGATGACCGAGATTTCAGACGACGATGCCCTGGCAGAGTTCATGTTCCTGGGCTTGCGC
ATGCTGGACGGGGTGACATTCAGCGACTTCCGGAGGGAATTCGGAATGGAGATGAAGGAGCGTTTCGGTAAGGAGTTGGA
GGAGCTGACAGGTCTGGGGCTACTGGCCATGGACGACAGAGGAGTGCACCTGACCAGGCGCGGCATGCTGCTCTCCAACC
AGGTCTTTACCCGATTTCTGGAATAG

Upstream 100 bases:

>100_bases
CGCCATGGGTCACTATCAGGGTGCGAAAGCCTCCGTAACCGACTGCGGGACAGCCCGACGCGGTGAGCAGTCAGAGTACC
GAAAAGGAGTTACCTTCCCC

Downstream 100 bases:

>100_bases
CGCCCCCCGTCGCCGCCCCCGCATTTTCTCCTCGGAGCCATTATTAAATCTGCCCCCTATCCCCATCCCGGACACAGTGG
CAAACCACGATCCGATACGG

Product: putative oxygen-independent coproporphyrinogen III oxidase

Products: NA

Alternate protein names: Coprogen oxidase; Coproporphyrinogenase [H]

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MFTRLYIHIPFCLHKCPYCAFISQEGSPARREAYVELLQAEMRLAHAGIPSGRPLESVYFGGGTPSLLEPDQIGRILSLA
DTLFSLLPHAEITLEANPGTIDRAKLAGFRHSGVNRLSLGVQSLDDRMLASLGRIHSAAQAEQAVKAARATGFANIGIDL
IHALPGQTMEMWRHDLERALDLAPEHLSVYGLTIEEGTPFAQRYTHDRDLPDEDLSADMFLAADDLLGAAGYEHYEIANY
ALPGFRSRHNSGYWRRDGYLGLGAGAHSFLRGTGHGLRFANSSDVDEYAAAITRGQLPRQEMTEISDDDALAEFMFLGLR
MLDGVTFSDFRREFGMEMKERFGKELEELTGLGLLAMDDRGVHLTRRGMLLSNQVFTRFLE

Sequences:

>Translated_381_residues
MFTRLYIHIPFCLHKCPYCAFISQEGSPARREAYVELLQAEMRLAHAGIPSGRPLESVYFGGGTPSLLEPDQIGRILSLA
DTLFSLLPHAEITLEANPGTIDRAKLAGFRHSGVNRLSLGVQSLDDRMLASLGRIHSAAQAEQAVKAARATGFANIGIDL
IHALPGQTMEMWRHDLERALDLAPEHLSVYGLTIEEGTPFAQRYTHDRDLPDEDLSADMFLAADDLLGAAGYEHYEIANY
ALPGFRSRHNSGYWRRDGYLGLGAGAHSFLRGTGHGLRFANSSDVDEYAAAITRGQLPRQEMTEISDDDALAEFMFLGLR
MLDGVTFSDFRREFGMEMKERFGKELEELTGLGLLAMDDRGVHLTRRGMLLSNQVFTRFLE
>Mature_381_residues
MFTRLYIHIPFCLHKCPYCAFISQEGSPARREAYVELLQAEMRLAHAGIPSGRPLESVYFGGGTPSLLEPDQIGRILSLA
DTLFSLLPHAEITLEANPGTIDRAKLAGFRHSGVNRLSLGVQSLDDRMLASLGRIHSAAQAEQAVKAARATGFANIGIDL
IHALPGQTMEMWRHDLERALDLAPEHLSVYGLTIEEGTPFAQRYTHDRDLPDEDLSADMFLAADDLLGAAGYEHYEIANY
ALPGFRSRHNSGYWRRDGYLGLGAGAHSFLRGTGHGLRFANSSDVDEYAAAITRGQLPRQEMTEISDDDALAEFMFLGLR
MLDGVTFSDFRREFGMEMKERFGKELEELTGLGLLAMDDRGVHLTRRGMLLSNQVFTRFLE

Specific function: Anaerobic transformation of coproporphyrinogen-III into protoporphyrinogen-IX [H]

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=383, Percent_Identity=34.7258485639687, Blast_Score=181, Evalue=1e-45,
Organism=Escherichia coli, GI1789325, Length=380, Percent_Identity=35.2631578947368, Blast_Score=211, Evalue=5e-56,
Organism=Escherichia coli, GI87082341, Length=405, Percent_Identity=27.9012345679012, Blast_Score=140, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: =1.3.99.22 [H]

Molecular weight: Translated: 42323; Mature: 42323

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTRLYIHIPFCLHKCPYCAFISQEGSPARREAYVELLQAEMRLAHAGIPSGRPLESVYF
CCEEEEEECCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHEEE
GGGTPSLLEPDQIGRILSLADTLFSLLPHAEITLEANPGTIDRAKLAGFRHSGVNRLSLG
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHCHHHCCCHHHHHH
VQSLDDRMLASLGRIHSAAQAEQAVKAARATGFANIGIDLIHALPGQTMEMWRHDLERAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
DLAPEHLSVYGLTIEEGTPFAQRYTHDRDLPDEDLSADMFLAADDLLGAAGYEHYEIANY
HCCCCCEEEEEEEECCCCCHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHCCCCHHHHHHH
ALPGFRSRHNSGYWRRDGYLGLGAGAHSFLRGTGHGLRFANSSDVDEYAAAITRGQLPRQ
CCCCCCCCCCCCCEECCCCEEECCCHHHHHHCCCCCEEECCCCCHHHHHHHHHHCCCCHH
EMTEISDDDALAEFMFLGLRMLDGVTFSDFRREFGMEMKERFGKELEELTGLGLLAMDDR
HHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEECCC
GVHLTRRGMLLSNQVFTRFLE
CCEEEECCCHHHHHHHHHHCC
>Mature Secondary Structure
MFTRLYIHIPFCLHKCPYCAFISQEGSPARREAYVELLQAEMRLAHAGIPSGRPLESVYF
CCEEEEEECCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHEEE
GGGTPSLLEPDQIGRILSLADTLFSLLPHAEITLEANPGTIDRAKLAGFRHSGVNRLSLG
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHCHHHCCCHHHHHH
VQSLDDRMLASLGRIHSAAQAEQAVKAARATGFANIGIDLIHALPGQTMEMWRHDLERAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
DLAPEHLSVYGLTIEEGTPFAQRYTHDRDLPDEDLSADMFLAADDLLGAAGYEHYEIANY
HCCCCCEEEEEEEECCCCCHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHCCCCHHHHHHH
ALPGFRSRHNSGYWRRDGYLGLGAGAHSFLRGTGHGLRFANSSDVDEYAAAITRGQLPRQ
CCCCCCCCCCCCCEECCCCEEECCCHHHHHHCCCCCEEECCCCCHHHHHHHHHHCCCCHH
EMTEISDDDALAEFMFLGLRMLDGVTFSDFRREFGMEMKERFGKELEELTGLGLLAMDDR
HHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEECCC
GVHLTRRGMLLSNQVFTRFLE
CCEEEECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8757728; 8969508; 9384377; 1339421 [H]