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The map label for this gene is ribH

Identifier: 118579724

GI number: 118579724

Start: 1365340

End: 1365807

Strand: Reverse

Name: ribH

Synonym: Ppro_1296

Alternate gene names: 118579724

Gene position: 1365807-1365340 (Counterclockwise)

Preceding gene: 118579725

Following gene: 118579723

Centisome position: 34.08

GC content: 61.11

Gene sequence:

>468_bases
ATGCCGCGCTATTTTGAGGGAAAACTCGACGCCAAGGGCCAGAAGATCGGCATCGTTGTCAGTCGTTTCAACAGTTTCAT
AACCGAACGCCTGCTGGAGGGGGCCGTTGACGCGCTGGTCCGCCATGGCGCCGACGAGCAGGAGATCCATATAGCCCGTG
TCCCGGGTGCATTCGAGATCCCGCTGGCGGCGAAAAAGATGGCTGCCAGCGGAGCCTATGACGCTATCATCGCCCTGGGC
GCCGTCATCCGCGGCTCCACGCCCCACTTCGACTATGTTTCGTCGGAAGTGACCAAGGGGGTGGCGGCCGTATCCCTGGA
GAGCGGTGTTCCGATCTCCTTTGGCGTACTGACCACCGATTCCATCGAGCAGGCCGTTGAACGGGCCGGCACCAAGGCCG
GAAACAAGGGATTCGAGGCGGCGGTCACCGTCATCGAGACCGTCAACCTGCTGAGGAGCATCAACTAA

Upstream 100 bases:

>100_bases
TCTCCTCGGTTTGAGGACCCTTCGGGCTATTTTTCCTATCACATCGCCCAAAAGGTATGCTAGTATCCGGAGCTCTTTAG
GTTACGTGAGGGAGGTTACC

Downstream 100 bases:

>100_bases
TGGGACTGCGAAGGGAGTCGCGCGAACTGGCGCTGCAGATGCTCTACGCCCTTGATTCCAACGCATCCGTGGGCCCGCGG
GAGATGCTGCAGATGTTCCG

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MPRYFEGKLDAKGQKIGIVVSRFNSFITERLLEGAVDALVRHGADEQEIHIARVPGAFEIPLAAKKMAASGAYDAIIALG
AVIRGSTPHFDYVSSEVTKGVAAVSLESGVPISFGVLTTDSIEQAVERAGTKAGNKGFEAAVTVIETVNLLRSIN

Sequences:

>Translated_155_residues
MPRYFEGKLDAKGQKIGIVVSRFNSFITERLLEGAVDALVRHGADEQEIHIARVPGAFEIPLAAKKMAASGAYDAIIALG
AVIRGSTPHFDYVSSEVTKGVAAVSLESGVPISFGVLTTDSIEQAVERAGTKAGNKGFEAAVTVIETVNLLRSIN
>Mature_154_residues
PRYFEGKLDAKGQKIGIVVSRFNSFITERLLEGAVDALVRHGADEQEIHIARVPGAFEIPLAAKKMAASGAYDAIIALGA
VIRGSTPHFDYVSSEVTKGVAAVSLESGVPISFGVLTTDSIEQAVERAGTKAGNKGFEAAVTVIETVNLLRSIN

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family

Homologues:

Organism=Escherichia coli, GI1786617, Length=141, Percent_Identity=56.0283687943262, Blast_Score=166, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6324429, Length=126, Percent_Identity=34.1269841269841, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RISB_PELPD (A1ANJ6)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_900974.1
- ProteinModelPortal:   A1ANJ6
- SMR:   A1ANJ6
- STRING:   A1ANJ6
- GeneID:   4573173
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_1296
- eggNOG:   COG0054
- HOGENOM:   HBG311126
- OMA:   KAGNKGW
- PhylomeDB:   A1ANJ6
- ProtClustDB:   PRK00061
- HAMAP:   MF_00178
- InterPro:   IPR002180
- Gene3D:   G3DSA:3.40.50.960
- PANTHER:   PTHR21058
- TIGRFAMs:   TIGR00114

Pfam domain/function: PF00885 DMRL_synthase; SSF52121 DMRL_synthase

EC number: =2.5.1.9

Molecular weight: Translated: 16357; Mature: 16226

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRYFEGKLDAKGQKIGIVVSRFNSFITERLLEGAVDALVRHGADEQEIHIARVPGAFEI
CCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEC
PLAAKKMAASGAYDAIIALGAVIRGSTPHFDYVSSEVTKGVAAVSLESGVPISFGVLTTD
CHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEEECCCCCEEEEEECHH
SIEQAVERAGTKAGNKGFEAAVTVIETVNLLRSIN
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PRYFEGKLDAKGQKIGIVVSRFNSFITERLLEGAVDALVRHGADEQEIHIARVPGAFEI
CCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEC
PLAAKKMAASGAYDAIIALGAVIRGSTPHFDYVSSEVTKGVAAVSLESGVPISFGVLTTD
CHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEEECCCCCEEEEEECHH
SIEQAVERAGTKAGNKGFEAAVTVIETVNLLRSIN
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA