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The map label for this gene is queC

Identifier: 118579716

GI number: 118579716

Start: 1358107

End: 1358787

Strand: Direct

Name: queC

Synonym: Ppro_1288

Alternate gene names: 118579716

Gene position: 1358107-1358787 (Clockwise)

Preceding gene: 118579715

Following gene: 118579717

Centisome position: 33.88

GC content: 57.56

Gene sequence:

>681_bases
ATGGAAAAGAGAGCGGTAGTCCTCTACAGCGGTGGCCTGGACTCGACAACCTGTCTGGCAATGGCGAAGGCGGACGGTTT
TGCGCCCTATGCCATGAGCTTTTCCTATGGCCAGCGCCATGGCTTTGAACTTGAGGTAGCCAAGGCGAATGCCCGCCCCC
TGGGGGCTGTGGAGCATCTGGTTGTGGATTTTGACCTTCGCCGCATGGGCGGCAGTGCACTGACTGACGATATCAGCGTC
CCCAAGGAAGGTGTGGGGAGCGATATACCGGTGACCTATGTTCCGGCCCGCAACACCATTTTCCTCTCCTTTGCCCTTGG
GTGGGCCGAGGTGCTTGGTGCTTTTGACATCTATATCGGCGTTAATTCCCTGGACTATTCGGGGTACCCGGATTGCCGTC
CCGAGTTTGTCAGCGCATTCGAGGCACTGGCCAATCTGGCAACAAAGTCAGGGGTGGAAGGGCAGGGGCACTTCAGTATC
CGTACGCCGCTGATCAACATGACCAAGGCCGAGATCATCAAGGCTGGCGTTGCCCTGGGGGTGGATTACTCCTGGACCCA
CTCCTGTTATGATCCAGAGAGTGACGGAACTTCCTGCGGACGCTGTGATTCCTGCCGGTTGCGGCTGAAGGGATTTGCCG
AAGCAGGTCTTGTGGACCCGCTTACCTATTCTGGCAGATAG

Upstream 100 bases:

>100_bases
CTCCGGCGAAACTTTCAAATTCCCCGTTTGGGTTTTCTGTGTTCGTCTGCTACTATCCTCTACGGATAACTGATCAACTA
ATGGGAGGAGTGAACGAAAC

Downstream 100 bases:

>100_bases
TCCTTGATTATGCCTTGCTGTCGGATCGTGTCTTGAACTTCCTTACTGCTGTCGTACAATAGAAATGTATTGCAGTCAAC
ACACATCCAGAGGAGAACTG

Product: exsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MEKRAVVLYSGGLDSTTCLAMAKADGFAPYAMSFSYGQRHGFELEVAKANARPLGAVEHLVVDFDLRRMGGSALTDDISV
PKEGVGSDIPVTYVPARNTIFLSFALGWAEVLGAFDIYIGVNSLDYSGYPDCRPEFVSAFEALANLATKSGVEGQGHFSI
RTPLINMTKAEIIKAGVALGVDYSWTHSCYDPESDGTSCGRCDSCRLRLKGFAEAGLVDPLTYSGR

Sequences:

>Translated_226_residues
MEKRAVVLYSGGLDSTTCLAMAKADGFAPYAMSFSYGQRHGFELEVAKANARPLGAVEHLVVDFDLRRMGGSALTDDISV
PKEGVGSDIPVTYVPARNTIFLSFALGWAEVLGAFDIYIGVNSLDYSGYPDCRPEFVSAFEALANLATKSGVEGQGHFSI
RTPLINMTKAEIIKAGVALGVDYSWTHSCYDPESDGTSCGRCDSCRLRLKGFAEAGLVDPLTYSGR
>Mature_226_residues
MEKRAVVLYSGGLDSTTCLAMAKADGFAPYAMSFSYGQRHGFELEVAKANARPLGAVEHLVVDFDLRRMGGSALTDDISV
PKEGVGSDIPVTYVPARNTIFLSFALGWAEVLGAFDIYIGVNSLDYSGYPDCRPEFVSAFEALANLATKSGVEGQGHFSI
RTPLINMTKAEIIKAGVALGVDYSWTHSCYDPESDGTSCGRCDSCRLRLKGFAEAGLVDPLTYSGR

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=216, Percent_Identity=40.7407407407407, Blast_Score=126, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_PELPD (A1ANI8)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_900966.1
- ProteinModelPortal:   A1ANI8
- SMR:   A1ANI8
- STRING:   A1ANI8
- GeneID:   4573165
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_1288
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- PhylomeDB:   A1ANI8
- ProtClustDB:   CLSK827865
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 24247; Mature: 24247

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKRAVVLYSGGLDSTTCLAMAKADGFAPYAMSFSYGQRHGFELEVAKANARPLGAVEHL
CCCCEEEEEECCCCCHHEEEEECCCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCHHHE
VVDFDLRRMGGSALTDDISVPKEGVGSDIPVTYVPARNTIFLSFALGWAEVLGAFDIYIG
EEEEHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEHHHHHHHHHHEEEEEE
VNSLDYSGYPDCRPEFVSAFEALANLATKSGVEGQGHFSIRTPLINMTKAEIIKAGVALG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEECCHHHHHHHHHHHCC
VDYSWTHSCYDPESDGTSCGRCDSCRLRLKGFAEAGLVDPLTYSGR
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEKRAVVLYSGGLDSTTCLAMAKADGFAPYAMSFSYGQRHGFELEVAKANARPLGAVEHL
CCCCEEEEEECCCCCHHEEEEECCCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCHHHE
VVDFDLRRMGGSALTDDISVPKEGVGSDIPVTYVPARNTIFLSFALGWAEVLGAFDIYIG
EEEEHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEHHHHHHHHHHEEEEEE
VNSLDYSGYPDCRPEFVSAFEALANLATKSGVEGQGHFSIRTPLINMTKAEIIKAGVALG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEECCHHHHHHHHHHHCC
VDYSWTHSCYDPESDGTSCGRCDSCRLRLKGFAEAGLVDPLTYSGR
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA