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The map label for this gene is cirA [H]

Identifier: 118579660

GI number: 118579660

Start: 1285187

End: 1287223

Strand: Reverse

Name: cirA [H]

Synonym: Ppro_1231

Alternate gene names: 118579660

Gene position: 1287223-1285187 (Counterclockwise)

Preceding gene: 118579661

Following gene: 118579659

Centisome position: 32.12

GC content: 59.55

Gene sequence:

>2037_bases
ATGAAGCACCCGTTCGTCATTCTGTCACTCTGCAATGCCCTGGTCATGCCGCACATAATCGATTCCACTGCCCATGCGGA
CCAGAATGAAACAACCGCGCAACCAGATCAGCAGTCCACCGAAACAAAGAGTGCCGACACCACCCTTGACCGCATGGTCG
TCACCGCCACCAGAATCCAGGAATCCACCCTGGACATCCCCGCATCGGTTCAGGTCATCACCCAGGAGGAGATCAGAACA
TCATCGGCACGGGACGCGGGCGAGCTGATGGCCGAGGCAGGCATCGGCCACGTGCATAAGTACAACGGTGCCCAGACCGG
CAACGTAGAGATCAGGGGGCTTTCCACCGACCTGTTCACCGAGAGCAGCAGCAGGGTGCTGCTGCTGGTGAACGGCAACC
GGGCCGGCACCACCAACATGGCCAAAATTCCGGCCAGCGAGATCGAGCGCATCGAGATCGTAAAAGGTCCCGGCTCCGTA
CTGTACGGTTCCCAGGCCATGGGGGGTGTGATCAACATCATTACCAAACGCGGTACCGAGGAGGGAGTTCACGGCTCCAT
AGGCGCGGAGGGCGGTTCCTGGGGGTACTGGAAAAGCGGCGGCGATATACATGGCAAGAAATACGGCATCGACTATTTCA
TCTCCGGCGCAGCGTCGGCCAGCGACGACTACCGCACACCAAAGGGTTCCTACGACAACAACGCCTACGAGAGCGAAGAG
CTTTCCACCCGGCTCGGCTACAGTTTCCTGAACGACCACCGGGTTTCGGTCGGTTTCCAGCGCTGGGTCGGCAGGGACCT
GGGCTCTCCCGGCGCGGTCTACGCCAAGGACCCGGACGACTACTCCAAAAAGGCCCGTAACTCCTTCGATTTTGAATACA
CAAACAAAACCGCGACGCTCAAATACTACATCAACAACAACAAGGACGACTCCTACAGCACCGGCGGCATGGGCATGCCC
GGTCCGGGCAACGCGGACCGGTTCACCTCCAACAACCGCTCCCAGGGGGTCAGCATCCAGAACGTCTTCCCCATCGGCGT
ACACCGCATCATCATCGGCGGACAGTGGGACCGCAACTCCGTGGACACCTCCAGCAGCAGCGGCGCCCCCTACTATCCCG
ATTCACGTTACGACAACTACGCCGCCTTCGCCGAGGGGAGGCTCAGCCTGCTGAAGGAAAAACTGCTGCTCACCGCCGGC
GTGCGCTACGACTACTTCGACAACAACACCCTGTCAACCAAGGGGCTCACCAGTACCCCCGTCTCCCGTAGCATGGATCA
CGTCACCGGTCGGGGCGGCATAGTCTACAAGATCACCGACGGCCTCAGCCTGAAGGCTGCCATCGGAACGGCCTTCAGGG
CCCCCTCCCCCCGAGAACTGGCCAGCGACTACACCCTCTACGGCTATCGTACTCTGGGTAACCGCGACCTGGGACCGGAG
AAGAGCACCACCTACGAGGGAGGGGTGGAGTACGCCAAAGACCATCTCAAGGGGGGCTTCACCTTCTTTCACACCAGCTT
CTCCCACAAGATCGCCAGCTACTACGACAGCGCCCTGGGAGCGACCAGCTATAAAAACCTTTCCAGCGCCACGATCCAGG
GGATCGAGATGAACGCGGCCTATGACGTCGGCCTGGCAGCCGGCCTGGACATTTCCGTCCAACCGTTTGCAAACGTCACC
TACAAAACCAGATACGACGGTGAAAGCAAAGACAGCGCTAGCCACGGACACCTGCTGAACGTCCCCGAATGGACCGGCGC
CTTCGGTGTCAAAGCCGGCCAGGAGAAATGGGACGCAAAACTGATCATCAACTATTCGGGCAACGAGTACATCACGGACT
ACTCCGCCTCCTATCCCTATCCGGTGGTCAACAAGGGGGGCTTCATGACAATGGACATCAAGGGGGCCATCCGTCCGCTG
AAGAACCTGGAACTGACCCTCGCCGTGGAGAACCTGCTGGACAGGTACTACGAGTACATCAACGGCTATCCCATGCGGGG
AAGAACCTTTGTGGGAGGGGCCAGGTGGATTTTCTAA

Upstream 100 bases:

>100_bases
TGTCATGGGCCATACCATGGTGGGAAGGCCGGCAAGTAGGTCGCCCTGAGCCGGAAGACCTGTTTCGGAGCCATCTTCAT
TTCCCGAGGGAGGAAAACAA

Downstream 100 bases:

>100_bases
AATAGCCGTTTGCAACGCAACGGGACAACAAAACCCATCCTCTTACCATCCCACCCCTCCCCTTCAAGGGGAGGGGTGGG
ATCCCGCGGGAAACAGAACA

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 678; Mature: 678

Protein sequence:

>678_residues
MKHPFVILSLCNALVMPHIIDSTAHADQNETTAQPDQQSTETKSADTTLDRMVVTATRIQESTLDIPASVQVITQEEIRT
SSARDAGELMAEAGIGHVHKYNGAQTGNVEIRGLSTDLFTESSSRVLLLVNGNRAGTTNMAKIPASEIERIEIVKGPGSV
LYGSQAMGGVINIITKRGTEEGVHGSIGAEGGSWGYWKSGGDIHGKKYGIDYFISGAASASDDYRTPKGSYDNNAYESEE
LSTRLGYSFLNDHRVSVGFQRWVGRDLGSPGAVYAKDPDDYSKKARNSFDFEYTNKTATLKYYINNNKDDSYSTGGMGMP
GPGNADRFTSNNRSQGVSIQNVFPIGVHRIIIGGQWDRNSVDTSSSSGAPYYPDSRYDNYAAFAEGRLSLLKEKLLLTAG
VRYDYFDNNTLSTKGLTSTPVSRSMDHVTGRGGIVYKITDGLSLKAAIGTAFRAPSPRELASDYTLYGYRTLGNRDLGPE
KSTTYEGGVEYAKDHLKGGFTFFHTSFSHKIASYYDSALGATSYKNLSSATIQGIEMNAAYDVGLAAGLDISVQPFANVT
YKTRYDGESKDSASHGHLLNVPEWTGAFGVKAGQEKWDAKLIINYSGNEYITDYSASYPYPVVNKGGFMTMDIKGAIRPL
KNLELTLAVENLLDRYYEYINGYPMRGRTFVGGARWIF

Sequences:

>Translated_678_residues
MKHPFVILSLCNALVMPHIIDSTAHADQNETTAQPDQQSTETKSADTTLDRMVVTATRIQESTLDIPASVQVITQEEIRT
SSARDAGELMAEAGIGHVHKYNGAQTGNVEIRGLSTDLFTESSSRVLLLVNGNRAGTTNMAKIPASEIERIEIVKGPGSV
LYGSQAMGGVINIITKRGTEEGVHGSIGAEGGSWGYWKSGGDIHGKKYGIDYFISGAASASDDYRTPKGSYDNNAYESEE
LSTRLGYSFLNDHRVSVGFQRWVGRDLGSPGAVYAKDPDDYSKKARNSFDFEYTNKTATLKYYINNNKDDSYSTGGMGMP
GPGNADRFTSNNRSQGVSIQNVFPIGVHRIIIGGQWDRNSVDTSSSSGAPYYPDSRYDNYAAFAEGRLSLLKEKLLLTAG
VRYDYFDNNTLSTKGLTSTPVSRSMDHVTGRGGIVYKITDGLSLKAAIGTAFRAPSPRELASDYTLYGYRTLGNRDLGPE
KSTTYEGGVEYAKDHLKGGFTFFHTSFSHKIASYYDSALGATSYKNLSSATIQGIEMNAAYDVGLAAGLDISVQPFANVT
YKTRYDGESKDSASHGHLLNVPEWTGAFGVKAGQEKWDAKLIINYSGNEYITDYSASYPYPVVNKGGFMTMDIKGAIRPL
KNLELTLAVENLLDRYYEYINGYPMRGRTFVGGARWIF
>Mature_678_residues
MKHPFVILSLCNALVMPHIIDSTAHADQNETTAQPDQQSTETKSADTTLDRMVVTATRIQESTLDIPASVQVITQEEIRT
SSARDAGELMAEAGIGHVHKYNGAQTGNVEIRGLSTDLFTESSSRVLLLVNGNRAGTTNMAKIPASEIERIEIVKGPGSV
LYGSQAMGGVINIITKRGTEEGVHGSIGAEGGSWGYWKSGGDIHGKKYGIDYFISGAASASDDYRTPKGSYDNNAYESEE
LSTRLGYSFLNDHRVSVGFQRWVGRDLGSPGAVYAKDPDDYSKKARNSFDFEYTNKTATLKYYINNNKDDSYSTGGMGMP
GPGNADRFTSNNRSQGVSIQNVFPIGVHRIIIGGQWDRNSVDTSSSSGAPYYPDSRYDNYAAFAEGRLSLLKEKLLLTAG
VRYDYFDNNTLSTKGLTSTPVSRSMDHVTGRGGIVYKITDGLSLKAAIGTAFRAPSPRELASDYTLYGYRTLGNRDLGPE
KSTTYEGGVEYAKDHLKGGFTFFHTSFSHKIASYYDSALGATSYKNLSSATIQGIEMNAAYDVGLAAGLDISVQPFANVT
YKTRYDGESKDSASHGHLLNVPEWTGAFGVKAGQEKWDAKLIINYSGNEYITDYSASYPYPVVNKGGFMTMDIKGAIRPL
KNLELTLAVENLLDRYYEYINGYPMRGRTFVGGARWIF

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=722, Percent_Identity=25.207756232687, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1790405, Length=147, Percent_Identity=30.6122448979592, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1786798, Length=160, Percent_Identity=33.125, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 74001; Mature: 74001

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHPFVILSLCNALVMPHIIDSTAHADQNETTAQPDQQSTETKSADTTLDRMVVTATRIQ
CCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
ESTLDIPASVQVITQEEIRTSSARDAGELMAEAGIGHVHKYNGAQTGNVEIRGLSTDLFT
HHHCCCCCEEEEEEHHHHHCCCCCHHHHHHHHCCCCCEEECCCCCCCCEEEEEECHHHCC
ESSSRVLLLVNGNRAGTTNMAKIPASEIERIEIVKGPGSVLYGSQAMGGVINIITKRGTE
CCCCEEEEEEECCCCCCCCEEECCHHHCCEEEEEECCCCEEECCHHHCCCEEEEECCCCC
EGVHGSIGAEGGSWGYWKSGGDIHGKKYGIDYFISGAASASDDYRTPKGSYDNNAYESEE
CCCCCCCCCCCCCCCCCCCCCCCCCEEECCEEEEECCCCCCCCCCCCCCCCCCCCCCHHH
LSTRLGYSFLNDHRVSVGFQRWVGRDLGSPGAVYAKDPDDYSKKARNSFDFEYTNKTATL
HHHHHCHHHHCCCEEEEHHHHHHCCCCCCCCEEEECCCHHHHHHHCCCCCEEECCCEEEE
KYYINNNKDDSYSTGGMGMPGPGNADRFTSNNRSQGVSIQNVFPIGVHRIIIGGQWDRNS
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEECCCCCCC
VDTSSSSGAPYYPDSRYDNYAAFAEGRLSLLKEKLLLTAGVRYDYFDNNTLSTKGLTSTP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCC
VSRSMDHVTGRGGIVYKITDGLSLKAAIGTAFRAPSPRELASDYTLYGYRTLGNRDLGPE
HHHHHHHHCCCCCEEEEEECCCEEEEHHHHHHCCCCCHHHHCCCEEEEEEECCCCCCCCC
KSTTYEGGVEYAKDHLKGGFTFFHTSFSHKIASYYDSALGATSYKNLSSATIQGIEMNAA
CCCCCCCCHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCE
YDVGLAAGLDISVQPFANVTYKTRYDGESKDSASHGHLLNVPEWTGAFGVKAGQEKWDAK
ECCCEECCCCEEECCCCCEEEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCEE
LIINYSGNEYITDYSASYPYPVVNKGGFMTMDIKGAIRPLKNLELTLAVENLLDRYYEYI
EEEEECCCEEEEECCCCCCCCEECCCCEEEEECHHHHCCHHCCEEEEHHHHHHHHHHHHH
NGYPMRGRTFVGGARWIF
CCCCCCCCEEECCEEECC
>Mature Secondary Structure
MKHPFVILSLCNALVMPHIIDSTAHADQNETTAQPDQQSTETKSADTTLDRMVVTATRIQ
CCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
ESTLDIPASVQVITQEEIRTSSARDAGELMAEAGIGHVHKYNGAQTGNVEIRGLSTDLFT
HHHCCCCCEEEEEEHHHHHCCCCCHHHHHHHHCCCCCEEECCCCCCCCEEEEEECHHHCC
ESSSRVLLLVNGNRAGTTNMAKIPASEIERIEIVKGPGSVLYGSQAMGGVINIITKRGTE
CCCCEEEEEEECCCCCCCCEEECCHHHCCEEEEEECCCCEEECCHHHCCCEEEEECCCCC
EGVHGSIGAEGGSWGYWKSGGDIHGKKYGIDYFISGAASASDDYRTPKGSYDNNAYESEE
CCCCCCCCCCCCCCCCCCCCCCCCCEEECCEEEEECCCCCCCCCCCCCCCCCCCCCCHHH
LSTRLGYSFLNDHRVSVGFQRWVGRDLGSPGAVYAKDPDDYSKKARNSFDFEYTNKTATL
HHHHHCHHHHCCCEEEEHHHHHHCCCCCCCCEEEECCCHHHHHHHCCCCCEEECCCEEEE
KYYINNNKDDSYSTGGMGMPGPGNADRFTSNNRSQGVSIQNVFPIGVHRIIIGGQWDRNS
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEECCCCCCC
VDTSSSSGAPYYPDSRYDNYAAFAEGRLSLLKEKLLLTAGVRYDYFDNNTLSTKGLTSTP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCC
VSRSMDHVTGRGGIVYKITDGLSLKAAIGTAFRAPSPRELASDYTLYGYRTLGNRDLGPE
HHHHHHHHCCCCCEEEEEECCCEEEEHHHHHHCCCCCHHHHCCCEEEEEEECCCCCCCCC
KSTTYEGGVEYAKDHLKGGFTFFHTSFSHKIASYYDSALGATSYKNLSSATIQGIEMNAA
CCCCCCCCHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCE
YDVGLAAGLDISVQPFANVTYKTRYDGESKDSASHGHLLNVPEWTGAFGVKAGQEKWDAK
ECCCEECCCCEEECCCCCEEEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCEE
LIINYSGNEYITDYSASYPYPVVNKGGFMTMDIKGAIRPLKNLELTLAVENLLDRYYEYI
EEEEECCCEEEEECCCCCCCCEECCCCEEEEECHHHHCCHHCCEEEEHHHHHHHHHHHHH
NGYPMRGRTFVGGARWIF
CCCCCCCCEEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]