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The map label for this gene is btuB [H]

Identifier: 118579657

GI number: 118579657

Start: 1281295

End: 1283166

Strand: Reverse

Name: btuB [H]

Synonym: Ppro_1228

Alternate gene names: 118579657

Gene position: 1283166-1281295 (Counterclockwise)

Preceding gene: 118579658

Following gene: 118579656

Centisome position: 32.02

GC content: 62.02

Gene sequence:

>1872_bases
ATGCATATCCGTCTGATCCCCGGCATCTCCCTGCTGACCCTGTCGCTGCTGAGCGGCACATCCCTGGGCGCGGAAACAGC
CAAAGAAGAACCCTACAGCCTGGGCGAAGTTGTCGTCACCTCGGAACGACTGAAAGAGTACATCACAAACCATCCGCTTG
ATGTGACGACGGTGGAGCGCGGGGAGATCGTAAGCCGCAACCTGGGGAGCGTGGAGGAGATCCTCAAGACCATGCCAGGG
GTGGAGGTCTATTCCAGCGCCGGGGTCGGCTCGCGCATCTCCATCAGAGGTTCGGGCCGCTCCGGCAGCGTGATGGTTCT
CCTGAACGGCAGGCCGCTCAACTCAAACCAGTACGGCAGCCAGGACTTGAGCGCCATCCCGGTGGACAGCATCCAGTCGG
TTTCGGTCTTCAAGCCGCCGGTTCCGGTCTGGCTCGGTCCGGGGGGGAGCGACGGCGCCATCAACATCATCACCCGAACG
CCGAAACAGGGGGGGGGCAAGGAGAAACAGCGCAGTTCGCTTAAGGGGGGTGGAGGCTCCTACGGTCTGGTGGAGGGAAG
TGTAAGCCACCAACTGCCGGTTTCCGACAGTACCGTCCTGCTCGCAGCCACCGGAAACCACCGTGACGGCAAACGCACCA
ACAGCGACCGCAACGACGGCGCCTTCAACCTGAACTGGAATCGCCAGGGAGACGAGGGGCGTCGCTACGAGTTCAACGGC
CGCTACTACCAGGCCGAATTCGGCTCGCCCGGACCGGTGGACAACGAGACCCCCCATGCACGCCAGGAGTACCGCAAGGG
TTCCCTGGACGCTCGCTACTCCGGCCTGCTGGGGCAATCGGGAACCGTCAGCGCCACCGCCTACGGCGACATGATCTATC
TGAAAGACACTGACCAGTCCGGCTCCCGCTACACCCTGAACGACAACAAGGCCGGCCTCAAGCTGGACACCACCTGGTCG
GATGAATCTGAAAACTGGGACCTGCGTCTGGGCGGGATGACCGAGTGGAACGGCTATGACCATACCCTGAGCGGAGAGCA
CGAGCGCTTCAGGAACGGCCTCAGCGTGCAGTACGACCGCAGATTCGGCCCATTGACAACCACCTTCGGCCTGCGGGGGG
ACCTGACCAACGACTTCGGCGCTAACCCGGGGGGAACCATCGGGCTGGGTTGGGGCATTGCGGACAAGACGCTGCTCAAG
CTGCGGGCCGGCTACACGGTGAACATCCCCCTGTTCGGACAGCTCTACCAGACCAGCCACGGCTCCATCGACCAGACACG
GGGCAATCCGGACCTGAAAAAGGAGCGGGTCTGGTCCTATGAAATAGGGCTGGAACACACCTTCGCCAAGGACCGGTTGC
TGCAGCTGACCCTGTTCAGGAGCGACACCGTCGACCTGATCAGTTCCCGCCGGGGGAGCGATATGATCTATCGGCCGGTG
AACATACGGGGCGCCGAACGCCAAGGGGGCGAGATCATGGCCACGTACGCCTGGGACAACGGCCCGACCCTGGAAGCCAG
CCTGACCATCCAGGACTCGGCGGTCAAGAGCACCGGCAAGAAGCTCCCCTACACGCCCGGCCTGAAGATGAAATACACAC
TCTCCTACACCCTCCCCCGCCTGGCCACCAGACTGGAGACCACGGTCCGCTACGAAGGGAGCCGTTACAGTCAGGCGGAG
AACAAGAGCTACCAGCGGATGGACGACGCCGTTCTGGTGGACCTGAAGGCGACCCAACCGTTCAAGATCGGAAAAATAGC
CACAGAAATCTATCTGAGGGTTGATAATCTCTTCGATACGGCGTATGAAACTCATCTGGGGCATCCCGATGACGGCATCC
GTGCCGCCGCCGGCATACAGATGAGATTCTAG

Upstream 100 bases:

>100_bases
ACAGGTTATTCGGCTGTAGTGAAGATCCTTCCATCTTTCTTCGCGAACTTCGCGTGAATGGCCGCTTTTTCCAGATAAAA
ACCAACCAAAGGAACCTCCC

Downstream 100 bases:

>100_bases
GGAGGGCTTGTGTGATGAATGATCAGACGACGCAGAATCAGGACGTGTTTCCCCAGGTGCGCATCAAATCTCCGGTGATG
GAGGCCTGGCTCAACTCCTT

Product: TonB-dependent receptor

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 623; Mature: 623

Protein sequence:

>623_residues
MHIRLIPGISLLTLSLLSGTSLGAETAKEEPYSLGEVVVTSERLKEYITNHPLDVTTVERGEIVSRNLGSVEEILKTMPG
VEVYSSAGVGSRISIRGSGRSGSVMVLLNGRPLNSNQYGSQDLSAIPVDSIQSVSVFKPPVPVWLGPGGSDGAINIITRT
PKQGGGKEKQRSSLKGGGGSYGLVEGSVSHQLPVSDSTVLLAATGNHRDGKRTNSDRNDGAFNLNWNRQGDEGRRYEFNG
RYYQAEFGSPGPVDNETPHARQEYRKGSLDARYSGLLGQSGTVSATAYGDMIYLKDTDQSGSRYTLNDNKAGLKLDTTWS
DESENWDLRLGGMTEWNGYDHTLSGEHERFRNGLSVQYDRRFGPLTTTFGLRGDLTNDFGANPGGTIGLGWGIADKTLLK
LRAGYTVNIPLFGQLYQTSHGSIDQTRGNPDLKKERVWSYEIGLEHTFAKDRLLQLTLFRSDTVDLISSRRGSDMIYRPV
NIRGAERQGGEIMATYAWDNGPTLEASLTIQDSAVKSTGKKLPYTPGLKMKYTLSYTLPRLATRLETTVRYEGSRYSQAE
NKSYQRMDDAVLVDLKATQPFKIGKIATEIYLRVDNLFDTAYETHLGHPDDGIRAAAGIQMRF

Sequences:

>Translated_623_residues
MHIRLIPGISLLTLSLLSGTSLGAETAKEEPYSLGEVVVTSERLKEYITNHPLDVTTVERGEIVSRNLGSVEEILKTMPG
VEVYSSAGVGSRISIRGSGRSGSVMVLLNGRPLNSNQYGSQDLSAIPVDSIQSVSVFKPPVPVWLGPGGSDGAINIITRT
PKQGGGKEKQRSSLKGGGGSYGLVEGSVSHQLPVSDSTVLLAATGNHRDGKRTNSDRNDGAFNLNWNRQGDEGRRYEFNG
RYYQAEFGSPGPVDNETPHARQEYRKGSLDARYSGLLGQSGTVSATAYGDMIYLKDTDQSGSRYTLNDNKAGLKLDTTWS
DESENWDLRLGGMTEWNGYDHTLSGEHERFRNGLSVQYDRRFGPLTTTFGLRGDLTNDFGANPGGTIGLGWGIADKTLLK
LRAGYTVNIPLFGQLYQTSHGSIDQTRGNPDLKKERVWSYEIGLEHTFAKDRLLQLTLFRSDTVDLISSRRGSDMIYRPV
NIRGAERQGGEIMATYAWDNGPTLEASLTIQDSAVKSTGKKLPYTPGLKMKYTLSYTLPRLATRLETTVRYEGSRYSQAE
NKSYQRMDDAVLVDLKATQPFKIGKIATEIYLRVDNLFDTAYETHLGHPDDGIRAAAGIQMRF
>Mature_623_residues
MHIRLIPGISLLTLSLLSGTSLGAETAKEEPYSLGEVVVTSERLKEYITNHPLDVTTVERGEIVSRNLGSVEEILKTMPG
VEVYSSAGVGSRISIRGSGRSGSVMVLLNGRPLNSNQYGSQDLSAIPVDSIQSVSVFKPPVPVWLGPGGSDGAINIITRT
PKQGGGKEKQRSSLKGGGGSYGLVEGSVSHQLPVSDSTVLLAATGNHRDGKRTNSDRNDGAFNLNWNRQGDEGRRYEFNG
RYYQAEFGSPGPVDNETPHARQEYRKGSLDARYSGLLGQSGTVSATAYGDMIYLKDTDQSGSRYTLNDNKAGLKLDTTWS
DESENWDLRLGGMTEWNGYDHTLSGEHERFRNGLSVQYDRRFGPLTTTFGLRGDLTNDFGANPGGTIGLGWGIADKTLLK
LRAGYTVNIPLFGQLYQTSHGSIDQTRGNPDLKKERVWSYEIGLEHTFAKDRLLQLTLFRSDTVDLISSRRGSDMIYRPV
NIRGAERQGGEIMATYAWDNGPTLEASLTIQDSAVKSTGKKLPYTPGLKMKYTLSYTLPRLATRLETTVRYEGSRYSQAE
NKSYQRMDDAVLVDLKATQPFKIGKIATEIYLRVDNLFDTAYETHLGHPDDGIRAAAGIQMRF

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: COG4206

COG function: function code H; Outer membrane cobalamin receptor protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790405, Length=634, Percent_Identity=25.3943217665615, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010101
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 68399; Mature: 68399

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIRLIPGISLLTLSLLSGTSLGAETAKEEPYSLGEVVVTSERLKEYITNHPLDVTTVER
CEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCEEEEECC
GEIVSRNLGSVEEILKTMPGVEVYSSAGVGSRISIRGSGRSGSVMVLLNGRPLNSNQYGS
CCHHHCCCCHHHHHHHHCCCCEEEECCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCC
QDLSAIPVDSIQSVSVFKPPVPVWLGPGGSDGAINIITRTPKQGGGKEKQRSSLKGGGGS
CCCCCCCCCCCCCCEEECCCCCEEECCCCCCCEEEEEEECCCCCCCCHHHHHHCCCCCCC
YGLVEGSVSHQLPVSDSTVLLAATGNHRDGKRTNSDRNDGAFNLNWNRQGDEGRRYEFNG
CEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEECC
RYYQAEFGSPGPVDNETPHARQEYRKGSLDARYSGLLGQSGTVSATAYGDMIYLKDTDQS
EEEEEECCCCCCCCCCCCHHHHHHHCCCCCCHHHHCCCCCCCEEEEEECCEEEEEECCCC
GSRYTLNDNKAGLKLDTTWSDESENWDLRLGGMTEWNGYDHTLSGEHERFRNGLSVQYDR
CCEEEECCCCCCEEEECCCCCCCCCCEEEECCEECCCCCCCCCCCCHHHHHCCCCEEECC
RFGPLTTTFGLRGDLTNDFGANPGGTIGLGWGIADKTLLKLRAGYTVNIPLFGQLYQTSH
CCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCEEECCCCEEEEECCC
GSIDQTRGNPDLKKERVWSYEIGLEHTFAKDRLLQLTLFRSDTVDLISSRRGSDMIYRPV
CCCCCCCCCCCCCHHEEEEEECCCCHHHCCCEEEEEEEECCCCHHHHHCCCCCCEEEECC
NIRGAERQGGEIMATYAWDNGPTLEASLTIQDSAVKSTGKKLPYTPGLKMKYTLSYTLPR
CCCCCCCCCCEEEEEEEECCCCEEEEEEEEEHHHHHHCCCCCCCCCCCEEEEEEEECHHH
LATRLETTVRYEGSRYSQAENKSYQRMDDAVLVDLKATQPFKIGKIATEIYLRVDNLFDT
HHHHHHHEEEECCCCCCCHHCCHHHHCCCEEEEEEECCCCEEHHHEEEEEEEEEHHHHHH
AYETHLGHPDDGIRAAAGIQMRF
HHHHCCCCCCCCCEEECCEEECC
>Mature Secondary Structure
MHIRLIPGISLLTLSLLSGTSLGAETAKEEPYSLGEVVVTSERLKEYITNHPLDVTTVER
CEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCEEEEECC
GEIVSRNLGSVEEILKTMPGVEVYSSAGVGSRISIRGSGRSGSVMVLLNGRPLNSNQYGS
CCHHHCCCCHHHHHHHHCCCCEEEECCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCC
QDLSAIPVDSIQSVSVFKPPVPVWLGPGGSDGAINIITRTPKQGGGKEKQRSSLKGGGGS
CCCCCCCCCCCCCCEEECCCCCEEECCCCCCCEEEEEEECCCCCCCCHHHHHHCCCCCCC
YGLVEGSVSHQLPVSDSTVLLAATGNHRDGKRTNSDRNDGAFNLNWNRQGDEGRRYEFNG
CEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEECC
RYYQAEFGSPGPVDNETPHARQEYRKGSLDARYSGLLGQSGTVSATAYGDMIYLKDTDQS
EEEEEECCCCCCCCCCCCHHHHHHHCCCCCCHHHHCCCCCCCEEEEEECCEEEEEECCCC
GSRYTLNDNKAGLKLDTTWSDESENWDLRLGGMTEWNGYDHTLSGEHERFRNGLSVQYDR
CCEEEECCCCCCEEEECCCCCCCCCCEEEECCEECCCCCCCCCCCCHHHHHCCCCEEECC
RFGPLTTTFGLRGDLTNDFGANPGGTIGLGWGIADKTLLKLRAGYTVNIPLFGQLYQTSH
CCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCEEECCCCEEEEECCC
GSIDQTRGNPDLKKERVWSYEIGLEHTFAKDRLLQLTLFRSDTVDLISSRRGSDMIYRPV
CCCCCCCCCCCCCHHEEEEEECCCCHHHCCCEEEEEEEECCCCHHHHHCCCCCCEEEECC
NIRGAERQGGEIMATYAWDNGPTLEASLTIQDSAVKSTGKKLPYTPGLKMKYTLSYTLPR
CCCCCCCCCCEEEEEEEECCCCEEEEEEEEEHHHHHHCCCCCCCCCCCEEEEEEEECHHH
LATRLETTVRYEGSRYSQAENKSYQRMDDAVLVDLKATQPFKIGKIATEIYLRVDNLFDT
HHHHHHHEEEECCCCCCCHHCCHHHHCCCEEEEEEECCCCEEHHHEEEEEEEEEHHHHHH
AYETHLGHPDDGIRAAAGIQMRF
HHHHCCCCCCCCCEEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA