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The map label for this gene is xerD [H]

Identifier: 118579574

GI number: 118579574

Start: 1189805

End: 1190692

Strand: Direct

Name: xerD [H]

Synonym: Ppro_1142

Alternate gene names: 118579574

Gene position: 1189805-1190692 (Clockwise)

Preceding gene: 118579564

Following gene: 118579575

Centisome position: 29.69

GC content: 64.3

Gene sequence:

>888_bases
GTGAACGAGTACCTGGACCTATTCCTGGGCTACATCGCCGTGGAACGGGGGCTTGCGACCAACACCCGCCAGGCCTACAG
TCGCGATCTGGGGCGTTACCTCGATTTCCTGGCTGAGCGGGGGAAAAACGAGCCGGCCGAGGTGACGGCGGCCGATATCG
CCTCCTTTCTGGTAAGACTGAGAGATGAGGGGCTCGCCCCGGCCAGCAGGGCGCGCTGTCTGTCGGCCATCCGCATGTTC
CACAAGTTCCTGATGATCGAGAAGTACTGTGACGACAACCCGTCGGCCATACTCGAAGCGCCCCGCACCCTGCACAAGCT
GCCGGCATTCCTGGAGCCGGCGGAGGTGGACCGCCTGTTTTCCGCCTGCGCCGGGACGTCGGGGGAGGATCTGCGTGACC
GTGCCATGCTGGAGCTGCTCTACGCCACCGGGCTAAGGGTATCGGAACTGGTCACTATCACGCTGCGCCAGGTCAACCTT
GATGTGGGATACCTGATGGTTGTGGGCAAGGGGGACAAGGAGCGGCTGGTGCCCATCGGCGAGTCGGCCCGCGGGCGGGT
CAGAAGGTATATCGAGGAGGCCCGCTACCGCCTCGATCCCCAGGGGCGCACCCCCCATCTCTTCCTCTCCCGCCTGGGGG
ATGCCATGAGCCGCCAGGCCTTCTGGAACCTGATCAGGAAGCGGGCGAAACTCGCCGCAATCGCGAAGGATATTTCGCCC
CATACCCTGCGCCACTCCTTCGCCACCCACCTGCTGGAGAACGGCGCCGACCTGCGCAGCGTGCAGATCATGCTGGGCCA
TGCCGATCTCTCCAGCACCCAGATCTACACCCACGTCACCCGCGAGCGGTTGAAAAGGCTGCACCAGGAGATTCATCCCC
GGGGATGA

Upstream 100 bases:

>100_bases
TACGGCGGTTTCAGGGAGAGATGGTCAGCACGCCGTGGAGTGACTTGCCCGGCTTAAAGAGGATGCCGTCGTCAACGCCG
CCATCGGCAAGGAGAGAGAC

Downstream 100 bases:

>100_bases
GGGGGCGGTGGGGAATTTTTCGTTGTCCAGGTTCCGGTTTTACCAACTCTTTGTTTTTGATGATAAAAGAAACTGCTCTG
CGCTGATGCAGCATCCGGTG

Product: tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MNEYLDLFLGYIAVERGLATNTRQAYSRDLGRYLDFLAERGKNEPAEVTAADIASFLVRLRDEGLAPASRARCLSAIRMF
HKFLMIEKYCDDNPSAILEAPRTLHKLPAFLEPAEVDRLFSACAGTSGEDLRDRAMLELLYATGLRVSELVTITLRQVNL
DVGYLMVVGKGDKERLVPIGESARGRVRRYIEEARYRLDPQGRTPHLFLSRLGDAMSRQAFWNLIRKRAKLAAIAKDISP
HTLRHSFATHLLENGADLRSVQIMLGHADLSSTQIYTHVTRERLKRLHQEIHPRG

Sequences:

>Translated_295_residues
MNEYLDLFLGYIAVERGLATNTRQAYSRDLGRYLDFLAERGKNEPAEVTAADIASFLVRLRDEGLAPASRARCLSAIRMF
HKFLMIEKYCDDNPSAILEAPRTLHKLPAFLEPAEVDRLFSACAGTSGEDLRDRAMLELLYATGLRVSELVTITLRQVNL
DVGYLMVVGKGDKERLVPIGESARGRVRRYIEEARYRLDPQGRTPHLFLSRLGDAMSRQAFWNLIRKRAKLAAIAKDISP
HTLRHSFATHLLENGADLRSVQIMLGHADLSSTQIYTHVTRERLKRLHQEIHPRG
>Mature_295_residues
MNEYLDLFLGYIAVERGLATNTRQAYSRDLGRYLDFLAERGKNEPAEVTAADIASFLVRLRDEGLAPASRARCLSAIRMF
HKFLMIEKYCDDNPSAILEAPRTLHKLPAFLEPAEVDRLFSACAGTSGEDLRDRAMLELLYATGLRVSELVTITLRQVNL
DVGYLMVVGKGDKERLVPIGESARGRVRRYIEEARYRLDPQGRTPHLFLSRLGDAMSRQAFWNLIRKRAKLAAIAKDISP
HTLRHSFATHLLENGADLRSVQIMLGHADLSSTQIYTHVTRERLKRLHQEIHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=292, Percent_Identity=46.5753424657534, Blast_Score=245, Evalue=3e-66,
Organism=Escherichia coli, GI1790244, Length=287, Percent_Identity=36.5853658536585, Blast_Score=177, Evalue=8e-46,
Organism=Escherichia coli, GI1790768, Length=170, Percent_Identity=32.3529411764706, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790767, Length=173, Percent_Identity=27.7456647398844, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33453; Mature: 33453

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEYLDLFLGYIAVERGLATNTRQAYSRDLGRYLDFLAERGKNEPAEVTAADIASFLVRL
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
RDEGLAPASRARCLSAIRMFHKFLMIEKYCDDNPSAILEAPRTLHKLPAFLEPAEVDRLF
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
SACAGTSGEDLRDRAMLELLYATGLRVSELVTITLRQVNLDVGYLMVVGKGDKERLVPIG
HHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCC
ESARGRVRRYIEEARYRLDPQGRTPHLFLSRLGDAMSRQAFWNLIRKRAKLAAIAKDISP
CCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
HTLRHSFATHLLENGADLRSVQIMLGHADLSSTQIYTHVTRERLKRLHQEIHPRG
HHHHHHHHHHHHHCCCCHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNEYLDLFLGYIAVERGLATNTRQAYSRDLGRYLDFLAERGKNEPAEVTAADIASFLVRL
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
RDEGLAPASRARCLSAIRMFHKFLMIEKYCDDNPSAILEAPRTLHKLPAFLEPAEVDRLF
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
SACAGTSGEDLRDRAMLELLYATGLRVSELVTITLRQVNLDVGYLMVVGKGDKERLVPIG
HHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCC
ESARGRVRRYIEEARYRLDPQGRTPHLFLSRLGDAMSRQAFWNLIRKRAKLAAIAKDISP
CCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
HTLRHSFATHLLENGADLRSVQIMLGHADLSSTQIYTHVTRERLKRLHQEIHPRG
HHHHHHHHHHHHHCCCCHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]