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The map label for this gene is atoS [C]

Identifier: 118579571

GI number: 118579571

Start: 1184443

End: 1186380

Strand: Reverse

Name: atoS [C]

Synonym: Ppro_1139

Alternate gene names: 118579571

Gene position: 1186380-1184443 (Counterclockwise)

Preceding gene: 118579572

Following gene: 118579570

Centisome position: 29.6

GC content: 59.96

Gene sequence:

>1938_bases
ATGCGGCTGATTCTGCAGGGGATCGAGTCCATCAGAAACGGCGATCTGGAGACCCGCATCCAGCTGAACCGCCACGACGA
GTGGAACGACATCGAGTCGGCCCTCAACCGCATGGCCGAGGAACGTCGGAAAGGCGAAGAGGCGCTCAGGGAGAGCGAGC
AGCGGTTGTCGGCCACGATTCAGGGATCGCCGATCCCGACCTTCGTGATCGACAGGGAGCAGAAGATCATCCACTGGAAC
CGGGCACTGGAACAGCTCAGCAACATCCGGGCCGACGAGGTGATCGGTTCGGATCTGGCCTGGAAGGCCTTTTACGATAA
AGAGCGGCCGACCCTGGCAAACCTGCTGGTCAGGGAGGAGACCTCTTCCCTATCGTCCTGGTATCGCGGCAAGTTCAGCA
AGTCCCGGCTGGTGGATGAGGCCTACGAGGCGACCGACTTCTTCCCCAAATGGGGCGAGGAGGGGAAGTGGCATTCGCTG
TTCACCAACCTCCCCGGAGGGAGCTTCACGGTCAACCACGACTACATCATCGAGGAGGTCAACGATGTGCTCTGCGACGT
GACCGGCTACACGCGGGAGGAGCTCATCGGTCAGCCCTGCGGCATCATCTGCCCCAAGGGGCCGCACCATTGCCCCATCT
TCGACCTGGGCAAGGAGAGCATCGACAACAGCGAGACCACGGTGAAGGCGAAAGACAGCAACCTTGTGCCGATCATCAAG
AGCGCCCGGAGAATCACCGTCGGAAGCAGGGAGGTGATCGTCGAAAACTTTCAGGACATCACCGAACAAAAGCTTCTGGA
GGCCCAACTGGGGCATGCCCAGAAGATGGAGGCTGTCGGCCAGTTGGCAGGCGGCGTTGCCCACGACTTCAACAACATCC
TGACCGCCATCATCGGCTACGGCAACCTGCTGCAGATGAAGGTCGGCGGGGACGAAACCCTGGAGAAGTACGTCAACCAG
ATACTCTACTCCGCCGAACGGGCAGCCACCCTCACCAACAGCCTGCTGGCATTCAGCAGGAAGCATATCATCCACGTACG
GGAGGTCAGCCTGAACGAGATCATCGCCAGGGCTGAAAAGCTCCTCTCACGGCTGGTGCCCGAAGACATCGAACTGCGCG
TCTTAGTCGGCCCCGACTGTTCCATCCTCGCCGACTCCACCCAGATGGAGCAGGTATTGATGAACCTGGTCACCAATGCC
CGGGACTCCATGCCCGACGGCGGCCGGCTCACCATCAGCACCGAGCCGGCCTTCCTGGACAGGGAGTTCGTGCACCGCCA
GGGCTACGGCGAACCGGGCAGCTTCGTCAAGGTGACGTTTTCGGACAACGGCGTCGGCATGGATGAGGGAATCAGGGAGC
GGATATTCGAGCCGTTTTTCACCACAAAGGAAACGGGCAAGGGCACCGGCCTGGGACTTGCCATCGTCTACGGGATCGTC
AAACAGCACGAAGGGTACATCGATGTATCGAGCCAGCCGGGCAGGGGTACAACCTTCACCATATACCTGCCGTTGATTAC
GGCAACCGACCAACCAGCCCACAGTCCGGACAGCAGGACATTGCCGCGGGGTACGGAAACCCTCCTCCTGGCTGAGGATG
AGCCACTGGTACGAGTCATCACCAAGACCATCCTGGAAGAGTTCGGCTATACGGTGATCGAGGCTGAGGATGGCGTCGAT
GCGGTTGACAGATTCCAGGAGCACCGGGAGCGGATCCAGCTGATCATCCTGGATGTGATCATGCCAAAAAAGAACGGCAG
ACAGGCCTATGACGCCATCAGGCTGATCCGCCCGGAGGTGAAGGCGCTGTTCATGAGCGGTTACGCCGACGACATCCTGA
GCAGCAAGGGGATCAGGGACGAAGAGCTGCATTTCGTTCCCAAACCCCTGGACCAGAGCATCCTCCTGCACAAGGTACGC
GAGATTCTGGACGCATGA

Upstream 100 bases:

>100_bases
GGGTTCCACCAGGGGCTTTATTCTGGCTGTCGCCGGCGGGCTGTTCGTCTCCCTCGGCCTTTTCACCATCGCCTTCAGTC
TCAGAAACATCCGCCGTCCC

Downstream 100 bases:

>100_bases
TCGCTCCCGTATCTGCCAGGCTCCTTCACGTATTCAATGGTAAGATATTCTCTCACAAAGCTCTACCGCACCTGCTGGTA
CAACCTCGCCGCAGAGGATC

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 645; Mature: 645

Protein sequence:

>645_residues
MRLILQGIESIRNGDLETRIQLNRHDEWNDIESALNRMAEERRKGEEALRESEQRLSATIQGSPIPTFVIDREQKIIHWN
RALEQLSNIRADEVIGSDLAWKAFYDKERPTLANLLVREETSSLSSWYRGKFSKSRLVDEAYEATDFFPKWGEEGKWHSL
FTNLPGGSFTVNHDYIIEEVNDVLCDVTGYTREELIGQPCGIICPKGPHHCPIFDLGKESIDNSETTVKAKDSNLVPIIK
SARRITVGSREVIVENFQDITEQKLLEAQLGHAQKMEAVGQLAGGVAHDFNNILTAIIGYGNLLQMKVGGDETLEKYVNQ
ILYSAERAATLTNSLLAFSRKHIIHVREVSLNEIIARAEKLLSRLVPEDIELRVLVGPDCSILADSTQMEQVLMNLVTNA
RDSMPDGGRLTISTEPAFLDREFVHRQGYGEPGSFVKVTFSDNGVGMDEGIRERIFEPFFTTKETGKGTGLGLAIVYGIV
KQHEGYIDVSSQPGRGTTFTIYLPLITATDQPAHSPDSRTLPRGTETLLLAEDEPLVRVITKTILEEFGYTVIEAEDGVD
AVDRFQEHRERIQLIILDVIMPKKNGRQAYDAIRLIRPEVKALFMSGYADDILSSKGIRDEELHFVPKPLDQSILLHKVR
EILDA

Sequences:

>Translated_645_residues
MRLILQGIESIRNGDLETRIQLNRHDEWNDIESALNRMAEERRKGEEALRESEQRLSATIQGSPIPTFVIDREQKIIHWN
RALEQLSNIRADEVIGSDLAWKAFYDKERPTLANLLVREETSSLSSWYRGKFSKSRLVDEAYEATDFFPKWGEEGKWHSL
FTNLPGGSFTVNHDYIIEEVNDVLCDVTGYTREELIGQPCGIICPKGPHHCPIFDLGKESIDNSETTVKAKDSNLVPIIK
SARRITVGSREVIVENFQDITEQKLLEAQLGHAQKMEAVGQLAGGVAHDFNNILTAIIGYGNLLQMKVGGDETLEKYVNQ
ILYSAERAATLTNSLLAFSRKHIIHVREVSLNEIIARAEKLLSRLVPEDIELRVLVGPDCSILADSTQMEQVLMNLVTNA
RDSMPDGGRLTISTEPAFLDREFVHRQGYGEPGSFVKVTFSDNGVGMDEGIRERIFEPFFTTKETGKGTGLGLAIVYGIV
KQHEGYIDVSSQPGRGTTFTIYLPLITATDQPAHSPDSRTLPRGTETLLLAEDEPLVRVITKTILEEFGYTVIEAEDGVD
AVDRFQEHRERIQLIILDVIMPKKNGRQAYDAIRLIRPEVKALFMSGYADDILSSKGIRDEELHFVPKPLDQSILLHKVR
EILDA
>Mature_645_residues
MRLILQGIESIRNGDLETRIQLNRHDEWNDIESALNRMAEERRKGEEALRESEQRLSATIQGSPIPTFVIDREQKIIHWN
RALEQLSNIRADEVIGSDLAWKAFYDKERPTLANLLVREETSSLSSWYRGKFSKSRLVDEAYEATDFFPKWGEEGKWHSL
FTNLPGGSFTVNHDYIIEEVNDVLCDVTGYTREELIGQPCGIICPKGPHHCPIFDLGKESIDNSETTVKAKDSNLVPIIK
SARRITVGSREVIVENFQDITEQKLLEAQLGHAQKMEAVGQLAGGVAHDFNNILTAIIGYGNLLQMKVGGDETLEKYVNQ
ILYSAERAATLTNSLLAFSRKHIIHVREVSLNEIIARAEKLLSRLVPEDIELRVLVGPDCSILADSTQMEQVLMNLVTNA
RDSMPDGGRLTISTEPAFLDREFVHRQGYGEPGSFVKVTFSDNGVGMDEGIRERIFEPFFTTKETGKGTGLGLAIVYGIV
KQHEGYIDVSSQPGRGTTFTIYLPLITATDQPAHSPDSRTLPRGTETLLLAEDEPLVRVITKTILEEFGYTVIEAEDGVD
AVDRFQEHRERIQLIILDVIMPKKNGRQAYDAIRLIRPEVKALFMSGYADDILSSKGIRDEELHFVPKPLDQSILLHKVR
EILDA

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=354, Percent_Identity=28.8135593220339, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI1790436, Length=254, Percent_Identity=31.496062992126, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1790300, Length=294, Percent_Identity=30.952380952381, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI48994928, Length=354, Percent_Identity=25.9887005649718, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788713, Length=230, Percent_Identity=30, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI145693157, Length=262, Percent_Identity=26.7175572519084, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI87081816, Length=269, Percent_Identity=24.1635687732342, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790346, Length=295, Percent_Identity=25.0847457627119, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789149, Length=237, Percent_Identity=25.7383966244726, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 72535; Mature: 72535

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLILQGIESIRNGDLETRIQLNRHDEWNDIESALNRMAEERRKGEEALRESEQRLSATI
CHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
QGSPIPTFVIDREQKIIHWNRALEQLSNIRADEVIGSDLAWKAFYDKERPTLANLLVREE
CCCCCCEEEECCCHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHCCCCCHHHHHHHHHH
TSSLSSWYRGKFSKSRLVDEAYEATDFFPKWGEEGKWHSLFTNLPGGSFTVNHDYIIEEV
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCEEECCHHHHHHH
NDVLCDVTGYTREELIGQPCGIICPKGPHHCPIFDLGKESIDNSETTVKAKDSNLVPIIK
HHHHHCCCCCCHHHHCCCCCCEECCCCCCCCCCCCCCHHHCCCCCCEEEECCCCCCHHHH
SARRITVGSREVIVENFQDITEQKLLEAQLGHAQKMEAVGQLAGGVAHDFNNILTAIIGY
CCCEEECCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GNLLQMKVGGDETLEKYVNQILYSAERAATLTNSLLAFSRKHIIHVREVSLNEIIARAEK
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHH
LLSRLVPEDIELRVLVGPDCSILADSTQMEQVLMNLVTNARDSMPDGGRLTISTEPAFLD
HHHHHCCCCCEEEEEECCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHH
REFVHRQGYGEPGSFVKVTFSDNGVGMDEGIRERIFEPFFTTKETGKGTGLGLAIVYGIV
HHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHCHHHCCCCCCCCCCHHHHHHHHHH
KQHEGYIDVSSQPGRGTTFTIYLPLITATDQPAHSPDSRTLPRGTETLLLAEDEPLVRVI
HHCCCEEEECCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCHHHHHH
TKTILEEFGYTVIEAEDGVDAVDRFQEHRERIQLIILDVIMPKKNGRQAYDAIRLIRPEV
HHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHEEHEECCCCCHHHHHHHHHHHHHH
KALFMSGYADDILSSKGIRDEELHFVPKPLDQSILLHKVREILDA
HHHHHHCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRLILQGIESIRNGDLETRIQLNRHDEWNDIESALNRMAEERRKGEEALRESEQRLSATI
CHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
QGSPIPTFVIDREQKIIHWNRALEQLSNIRADEVIGSDLAWKAFYDKERPTLANLLVREE
CCCCCCEEEECCCHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHCCCCCHHHHHHHHHH
TSSLSSWYRGKFSKSRLVDEAYEATDFFPKWGEEGKWHSLFTNLPGGSFTVNHDYIIEEV
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCEEECCHHHHHHH
NDVLCDVTGYTREELIGQPCGIICPKGPHHCPIFDLGKESIDNSETTVKAKDSNLVPIIK
HHHHHCCCCCCHHHHCCCCCCEECCCCCCCCCCCCCCHHHCCCCCCEEEECCCCCCHHHH
SARRITVGSREVIVENFQDITEQKLLEAQLGHAQKMEAVGQLAGGVAHDFNNILTAIIGY
CCCEEECCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GNLLQMKVGGDETLEKYVNQILYSAERAATLTNSLLAFSRKHIIHVREVSLNEIIARAEK
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHH
LLSRLVPEDIELRVLVGPDCSILADSTQMEQVLMNLVTNARDSMPDGGRLTISTEPAFLD
HHHHHCCCCCEEEEEECCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHH
REFVHRQGYGEPGSFVKVTFSDNGVGMDEGIRERIFEPFFTTKETGKGTGLGLAIVYGIV
HHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHCHHHCCCCCCCCCCHHHHHHHHHH
KQHEGYIDVSSQPGRGTTFTIYLPLITATDQPAHSPDSRTLPRGTETLLLAEDEPLVRVI
HHCCCEEEECCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCHHHHHH
TKTILEEFGYTVIEAEDGVDAVDRFQEHRERIQLIILDVIMPKKNGRQAYDAIRLIRPEV
HHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHEEHEECCCCCHHHHHHHHHHHHHH
KALFMSGYADDILSSKGIRDEELHFVPKPLDQSILLHKVREILDA
HHHHHHCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA