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The map label for this gene is acoR [H]

Identifier: 118579472

GI number: 118579472

Start: 1088734

End: 1090734

Strand: Reverse

Name: acoR [H]

Synonym: Ppro_1039

Alternate gene names: 118579472

Gene position: 1090734-1088734 (Counterclockwise)

Preceding gene: 118579473

Following gene: 118579466

Centisome position: 27.21

GC content: 61.82

Gene sequence:

>2001_bases
GTGTCAAACTCGTACACGAAAAACCATATCAGCGATGTCATCCGCTCGGTCAATTCCAACAACCTGCCCTCAATCAGGAG
CAACACTACCGCCCCCGTCATCCACAGCTCGTGGAAACGCTGCTTCAACGATTACAGCATCGACCCTTCATCAAAAAGCA
AACCCCGCATCATCACCGGCAGCGCCCTGAAGGAGTGCCAGGAACCGCTGGAGGAGTTCCTGTTCATCGCCAAGTCCGGC
ATGAAGAGCCTCTACGAGAAGATCGCCACGGCCGGCTACGTGATCCTGCTGGGAGACGCCAACGGCGTCACCATCGACTA
CATGGGCAACCCCGACACCGAGAAGGAGCATCGTGACGCTGGTCTGTACCTGGGCTCGCTCTGGGCTGAATCCGTGGAAG
GCACCTGCGGCGTGGGAACCTGCATCGAGGAAAAGCGGCCCATCACCATCCACCGCGACGAGCATTTCCGCGCCCGCCAC
ATCGGCTTGAGCTGTTCCACCACCCCGCTCTTCTTCCCCGACGGAACCCTGCTGGGCGTACTGGACATATCCCAGCTCCA
TCCGCCGCAATCACGGGACTCGCAACTACTCGCCCTGCAGATGCTCAGCTATTCCGCCCGCCTGATCGAGAACGCCTATT
TCATGCGCCTCTACAAGGACTGCTGGATCGTGCGCTTCAGCTGCATGAAGGCGTTCGTGGAGGTAGTGGCCGAGAGTTTT
CTGGCGGTGAGCAACGAGGGGTACGTGATCGCCGCCAACCAGAGCGCACTGACCCAGCTGCAGGGGCCGCAGCTCCCCAG
CCCCATCGGCCGCCACGTCAGTGCCGTGTTCGATCTTCGCATGGAAGAGCTCGTGGAGCATGCCACCCACAAGACAACAA
CGATCCTTCCCATCCGCTTCCTGGATACCGGATATCAGTACTTTGCCACCTTCCGCGCGCCCGAGAAGAAGAGCCCCCTT
TCGCCCCCCAAAAAAGAGACCAGGAGCAAGCCTTCCCCCCACTTCACCCTGGACTACCTGGCCGGGACCGACCCGCGCAT
GGCCTACAACGTGAACTGCGCCAAACGGCTGATGAACAGGAACATATCCATACTCCTGATCGGAGAAACCGGAACCGGCA
AGGAGGTCTTTGCCCGGGCGATACACGAGGCCAGTGACAGGGCCTCCAAACCGTTCGTGGCCCTGAACTGCGCCTCCATT
CCGGAGTCGCTGATCGAGAGCGAGCTGTTCGGCTACAAGCAGGGCGCGTTCACCGGCGCCAACAGCAAGGGGATGCGGGG
CAAGATCCTGCAGTCCAGCGGCGGCACCCTGTTTCTGGACGAAATCGGCGACATGCCCTTCAACCTGCAGACGCGCCTGC
TGCGGGTGCTGGCGGAGCGGGAGGTGCAGCCGCTGGGAAGTGAATCGGTCATCAAGGTCGATCTCAACATCATCTGCGCC
ACCCTGAGGAACCTGGAAGAGCTGGTGCGCGAGAAACAGTTCCGGGAGGACCTGTACTACCGCCTGAACGGCATCACCAT
CAAACTGCCCCCCCTGCGGGAGCGCACGGACAGGGCTCTGGTGATCGAGAACGCCCTGGCGGCCGAGGCCGAGCCGGGCG
TCGAAACAGGCCTCGCCCCCGAGGCGCTGGAAATCCTGGCCGCCTATGACTGGCCGGGCAACATCAGACAACTGCGCAAT
GCGCTGCGCTTCTCCATCGCCATCAGCGAGGGTGAAACCATTCATGCCAGGGACCTGCCCCCTGACCTGCTCAAAGCCCC
GACATCCGGCATAGCCCTGCCTGCGCCCGCCCCCAGCCCGGAGCCCCTTCCGGCACAGGATCCGGCTTCACTGCTGCCGG
ACCTGCCTCCCCAGGACGCCCAGGAACGGGAGAAACTGCTGCGAACGCTGAAGAAGAACAAGTGGAACATCACCGATGCC
TCGCGGGAGCTGTGCGTCAGTCGTTCCACCCTGTACCGCAAGATGAGCAAATACCACCTCATTCCGCCCAACGAGCTCTG
A

Upstream 100 bases:

>100_bases
GAGAAGTACCGGGACTAACCGCCCGTAGTGAAGACGATGAAAGTGATTCACCGATACAAAGTGTCACTCTCAATTCGGTT
GTCATGTCAGGAGAGGAACG

Downstream 100 bases:

>100_bases
CCTTCCGCACTCCTCTGTTGTCGTCCGAAGCGCCCTTACCAAAGGACTTCGGACGACAACCCATCGGAACGAACCGCACC
TCTTGTCCACCACCCCACCA

Product: Fis family GAF modulated sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 666; Mature: 665

Protein sequence:

>666_residues
MSNSYTKNHISDVIRSVNSNNLPSIRSNTTAPVIHSSWKRCFNDYSIDPSSKSKPRIITGSALKECQEPLEEFLFIAKSG
MKSLYEKIATAGYVILLGDANGVTIDYMGNPDTEKEHRDAGLYLGSLWAESVEGTCGVGTCIEEKRPITIHRDEHFRARH
IGLSCSTTPLFFPDGTLLGVLDISQLHPPQSRDSQLLALQMLSYSARLIENAYFMRLYKDCWIVRFSCMKAFVEVVAESF
LAVSNEGYVIAANQSALTQLQGPQLPSPIGRHVSAVFDLRMEELVEHATHKTTTILPIRFLDTGYQYFATFRAPEKKSPL
SPPKKETRSKPSPHFTLDYLAGTDPRMAYNVNCAKRLMNRNISILLIGETGTGKEVFARAIHEASDRASKPFVALNCASI
PESLIESELFGYKQGAFTGANSKGMRGKILQSSGGTLFLDEIGDMPFNLQTRLLRVLAEREVQPLGSESVIKVDLNIICA
TLRNLEELVREKQFREDLYYRLNGITIKLPPLRERTDRALVIENALAAEAEPGVETGLAPEALEILAAYDWPGNIRQLRN
ALRFSIAISEGETIHARDLPPDLLKAPTSGIALPAPAPSPEPLPAQDPASLLPDLPPQDAQEREKLLRTLKKNKWNITDA
SRELCVSRSTLYRKMSKYHLIPPNEL

Sequences:

>Translated_666_residues
MSNSYTKNHISDVIRSVNSNNLPSIRSNTTAPVIHSSWKRCFNDYSIDPSSKSKPRIITGSALKECQEPLEEFLFIAKSG
MKSLYEKIATAGYVILLGDANGVTIDYMGNPDTEKEHRDAGLYLGSLWAESVEGTCGVGTCIEEKRPITIHRDEHFRARH
IGLSCSTTPLFFPDGTLLGVLDISQLHPPQSRDSQLLALQMLSYSARLIENAYFMRLYKDCWIVRFSCMKAFVEVVAESF
LAVSNEGYVIAANQSALTQLQGPQLPSPIGRHVSAVFDLRMEELVEHATHKTTTILPIRFLDTGYQYFATFRAPEKKSPL
SPPKKETRSKPSPHFTLDYLAGTDPRMAYNVNCAKRLMNRNISILLIGETGTGKEVFARAIHEASDRASKPFVALNCASI
PESLIESELFGYKQGAFTGANSKGMRGKILQSSGGTLFLDEIGDMPFNLQTRLLRVLAEREVQPLGSESVIKVDLNIICA
TLRNLEELVREKQFREDLYYRLNGITIKLPPLRERTDRALVIENALAAEAEPGVETGLAPEALEILAAYDWPGNIRQLRN
ALRFSIAISEGETIHARDLPPDLLKAPTSGIALPAPAPSPEPLPAQDPASLLPDLPPQDAQEREKLLRTLKKNKWNITDA
SRELCVSRSTLYRKMSKYHLIPPNEL
>Mature_665_residues
SNSYTKNHISDVIRSVNSNNLPSIRSNTTAPVIHSSWKRCFNDYSIDPSSKSKPRIITGSALKECQEPLEEFLFIAKSGM
KSLYEKIATAGYVILLGDANGVTIDYMGNPDTEKEHRDAGLYLGSLWAESVEGTCGVGTCIEEKRPITIHRDEHFRARHI
GLSCSTTPLFFPDGTLLGVLDISQLHPPQSRDSQLLALQMLSYSARLIENAYFMRLYKDCWIVRFSCMKAFVEVVAESFL
AVSNEGYVIAANQSALTQLQGPQLPSPIGRHVSAVFDLRMEELVEHATHKTTTILPIRFLDTGYQYFATFRAPEKKSPLS
PPKKETRSKPSPHFTLDYLAGTDPRMAYNVNCAKRLMNRNISILLIGETGTGKEVFARAIHEASDRASKPFVALNCASIP
ESLIESELFGYKQGAFTGANSKGMRGKILQSSGGTLFLDEIGDMPFNLQTRLLRVLAEREVQPLGSESVIKVDLNIICAT
LRNLEELVREKQFREDLYYRLNGITIKLPPLRERTDRALVIENALAAEAEPGVETGLAPEALEILAAYDWPGNIRQLRNA
LRFSIAISEGETIHARDLPPDLLKAPTSGIALPAPAPSPEPLPAQDPASLLPDLPPQDAQEREKLLRTLKKNKWNITDAS
RELCVSRSTLYRKMSKYHLIPPNEL

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=316, Percent_Identity=45.5696202531646, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI1790437, Length=321, Percent_Identity=42.0560747663551, Blast_Score=238, Evalue=1e-63,
Organism=Escherichia coli, GI1790299, Length=329, Percent_Identity=43.161094224924, Blast_Score=230, Evalue=3e-61,
Organism=Escherichia coli, GI1788550, Length=306, Percent_Identity=39.8692810457516, Blast_Score=222, Evalue=6e-59,
Organism=Escherichia coli, GI1788905, Length=321, Percent_Identity=40.1869158878505, Blast_Score=216, Evalue=6e-57,
Organism=Escherichia coli, GI87082117, Length=303, Percent_Identity=39.9339933993399, Blast_Score=213, Evalue=4e-56,
Organism=Escherichia coli, GI1786524, Length=346, Percent_Identity=39.3063583815029, Blast_Score=202, Evalue=7e-53,
Organism=Escherichia coli, GI1789087, Length=302, Percent_Identity=37.4172185430464, Blast_Score=195, Evalue=6e-51,
Organism=Escherichia coli, GI1787583, Length=375, Percent_Identity=33.8666666666667, Blast_Score=188, Evalue=9e-49,
Organism=Escherichia coli, GI87082152, Length=306, Percent_Identity=36.2745098039216, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI87081872, Length=307, Percent_Identity=36.8078175895765, Blast_Score=168, Evalue=8e-43,
Organism=Escherichia coli, GI87081858, Length=652, Percent_Identity=22.8527607361963, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1789828, Length=268, Percent_Identity=35.0746268656716, Blast_Score=125, Evalue=1e-29,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 74081; Mature: 73949

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSYTKNHISDVIRSVNSNNLPSIRSNTTAPVIHSSWKRCFNDYSIDPSSKSKPRIITG
CCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEC
SALKECQEPLEEFLFIAKSGMKSLYEKIATAGYVILLGDANGVTIDYMGNPDTEKEHRDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEECCCCCCCHHHHHH
GLYLGSLWAESVEGTCGVGTCIEEKRPITIHRDEHFRARHIGLSCSTTPLFFPDGTLLGV
CHHHHHHHHHHCCCCCCCCCHHCCCCCEEEECCCCCCHHEECCCCCCCEEECCCCCEEEE
LDISQLHPPQSRDSQLLALQMLSYSARLIENAYFMRLYKDCWIVRFSCMKAFVEVVAESF
EEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAVSNEGYVIAANQSALTQLQGPQLPSPIGRHVSAVFDLRMEELVEHATHKTTTILPIRF
HHCCCCCEEEEECHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEE
LDTGYQYFATFRAPEKKSPLSPPKKETRSKPSPHFTLDYLAGTDPRMAYNVNCAKRLMNR
ECCCCEEEEEECCCCCCCCCCCCHHHHCCCCCCCEEEEEECCCCCCEEEECHHHHHHHCC
NISILLIGETGTGKEVFARAIHEASDRASKPFVALNCASIPESLIESELFGYKQGAFTGA
CCEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCC
NSKGMRGKILQSSGGTLFLDEIGDMPFNLQTRLLRVLAEREVQPLGSESVIKVDLNIICA
CCCCCCCEEEECCCCEEEEHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHH
TLRNLEELVREKQFREDLYYRLNGITIKLPPLRERTDRALVIENALAAEAEPGVETGLAP
HHHHHHHHHHHHHHHHHHHEEECCEEEECCCCCCCCCCEEEEEHHHHCCCCCCCCCCCCH
EALEILAAYDWPGNIRQLRNALRFSIAISEGETIHARDLPPDLLKAPTSGIALPAPAPSP
HHHHHHHCCCCCCHHHHHHHHHEEEEEECCCCEEECCCCCHHHHHCCCCCEECCCCCCCC
EPLPAQDPASLLPDLPPQDAQEREKLLRTLKKNKWNITDASRELCVSRSTLYRKMSKYHL
CCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
IPPNEL
CCCCCC
>Mature Secondary Structure 
SNSYTKNHISDVIRSVNSNNLPSIRSNTTAPVIHSSWKRCFNDYSIDPSSKSKPRIITG
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEC
SALKECQEPLEEFLFIAKSGMKSLYEKIATAGYVILLGDANGVTIDYMGNPDTEKEHRDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEECCCCCCCHHHHHH
GLYLGSLWAESVEGTCGVGTCIEEKRPITIHRDEHFRARHIGLSCSTTPLFFPDGTLLGV
CHHHHHHHHHHCCCCCCCCCHHCCCCCEEEECCCCCCHHEECCCCCCCEEECCCCCEEEE
LDISQLHPPQSRDSQLLALQMLSYSARLIENAYFMRLYKDCWIVRFSCMKAFVEVVAESF
EEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAVSNEGYVIAANQSALTQLQGPQLPSPIGRHVSAVFDLRMEELVEHATHKTTTILPIRF
HHCCCCCEEEEECHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEE
LDTGYQYFATFRAPEKKSPLSPPKKETRSKPSPHFTLDYLAGTDPRMAYNVNCAKRLMNR
ECCCCEEEEEECCCCCCCCCCCCHHHHCCCCCCCEEEEEECCCCCCEEEECHHHHHHHCC
NISILLIGETGTGKEVFARAIHEASDRASKPFVALNCASIPESLIESELFGYKQGAFTGA
CCEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCC
NSKGMRGKILQSSGGTLFLDEIGDMPFNLQTRLLRVLAEREVQPLGSESVIKVDLNIICA
CCCCCCCEEEECCCCEEEEHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHH
TLRNLEELVREKQFREDLYYRLNGITIKLPPLRERTDRALVIENALAAEAEPGVETGLAP
HHHHHHHHHHHHHHHHHHHEEECCEEEECCCCCCCCCCEEEEEHHHHCCCCCCCCCCCCH
EALEILAAYDWPGNIRQLRNALRFSIAISEGETIHARDLPPDLLKAPTSGIALPAPAPSP
HHHHHHHCCCCCCHHHHHHHHHEEEEEECCCCEEECCCCCHHHHHCCCCCEECCCCCCCC
EPLPAQDPASLLPDLPPQDAQEREKLLRTLKKNKWNITDASRELCVSRSTLYRKMSKYHL
CCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
IPPNEL
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]