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The map label for this gene is kdsC [H]

Identifier: 118579406

GI number: 118579406

Start: 1014061

End: 1014576

Strand: Direct

Name: kdsC [H]

Synonym: Ppro_0970

Alternate gene names: 118579406

Gene position: 1014061-1014576 (Clockwise)

Preceding gene: 118579405

Following gene: 118579407

Centisome position: 25.3

GC content: 56.78

Gene sequence:

>516_bases
ATGCAGGAGAAACTTAAAAAGATCAAACTACTGCTCCTGGATGTGGACGGCGTCATGACCGATGGCGGTATCGTGTTTGA
CGGCAACGGCCTGGAAACCAAGGTCTTCAACGTCAAGGACGGCCATGGTATCAAGATGCTCCAGCGTTACGGGATCCAAG
TGGGAGTCATTACCGGCAGAACCTCGGCCGTGGTGGATATCAGAACCCGTGAACTGGGCATCGAACTGGTGTACCAGGGG
GCTCTCAAGAAGATGGAAAGCTATGCCGACGTGAAGCAGAAAACCGGTCTGGATGACTGTCAGGTCGCTTACATGGGGGA
CGACGTCATTGATGTTCCGGTTATGAGGCGGGTCGGTTTTGCGGCCGCTCCTCCTGATGCGCTGCCGGAGGTGCTGGCCG
TTGCCGACTATGTGTCATCCCGCTCCGGCGGAAGGGGTGCGGTGCGAGAGGTATGCGATCTTATCCTCAAGGGGCGTGGC
TTCTGGCCTGAAATCGCCACGCGCTATGAGTTGTGA

Upstream 100 bases:

>100_bases
AGTACTCCATCACCTCCCTGTTTGTCTTTGACGACGACACAAGCAGTGTGCCCTGTGGCATCGTTCATCTGCACGACATT
CTGCGCTCGGGGATAGCCTG

Downstream 100 bases:

>100_bases
CGTGAGGTATACAAGCTCCATGCCAACTAGCCGGATAAACATACGTTTCGCTGGACAGCCCTCCGGCGCGATGCTATAGT
GCGCCAGTATGGTATCGTCC

Product: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MQEKLKKIKLLLLDVDGVMTDGGIVFDGNGLETKVFNVKDGHGIKMLQRYGIQVGVITGRTSAVVDIRTRELGIELVYQG
ALKKMESYADVKQKTGLDDCQVAYMGDDVIDVPVMRRVGFAAAPPDALPEVLAVADYVSSRSGGRGAVREVCDLILKGRG
FWPEIATRYEL

Sequences:

>Translated_171_residues
MQEKLKKIKLLLLDVDGVMTDGGIVFDGNGLETKVFNVKDGHGIKMLQRYGIQVGVITGRTSAVVDIRTRELGIELVYQG
ALKKMESYADVKQKTGLDDCQVAYMGDDVIDVPVMRRVGFAAAPPDALPEVLAVADYVSSRSGGRGAVREVCDLILKGRG
FWPEIATRYEL
>Mature_171_residues
MQEKLKKIKLLLLDVDGVMTDGGIVFDGNGLETKVFNVKDGHGIKMLQRYGIQVGVITGRTSAVVDIRTRELGIELVYQG
ALKKMESYADVKQKTGLDDCQVAYMGDDVIDVPVMRRVGFAAAPPDALPEVLAVADYVSSRSGGRGAVREVCDLILKGRG
FWPEIATRYEL

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=154, Percent_Identity=33.7662337662338, Blast_Score=93, Evalue=1e-19,
Organism=Escherichia coli, GI2367202, Length=161, Percent_Identity=47.8260869565217, Blast_Score=147, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 18691; Mature: 18691

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEKLKKIKLLLLDVDGVMTDGGIVFDGNGLETKVFNVKDGHGIKMLQRYGIQVGVITGR
CHHHHHHHEEEEEECCCEEECCCEEECCCCCEEEEEECCCCCCHHHHHHCCCEEEEEECC
TSAVVDIRTRELGIELVYQGALKKMESYADVKQKTGLDDCQVAYMGDDVIDVPVMRRVGF
CEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEECHHHHHHCCC
AAAPPDALPEVLAVADYVSSRSGGRGAVREVCDLILKGRGFWPEIATRYEL
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCC
>Mature Secondary Structure
MQEKLKKIKLLLLDVDGVMTDGGIVFDGNGLETKVFNVKDGHGIKMLQRYGIQVGVITGR
CHHHHHHHEEEEEECCCEEECCCEEECCCCCEEEEEECCCCCCHHHHHHCCCEEEEEECC
TSAVVDIRTRELGIELVYQGALKKMESYADVKQKTGLDDCQVAYMGDDVIDVPVMRRVGF
CEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEECHHHHHHCCC
AAAPPDALPEVLAVADYVSSRSGGRGAVREVCDLILKGRGFWPEIATRYEL
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]