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The map label for this gene is fabF [H]

Identifier: 118579363

GI number: 118579363

Start: 975867

End: 977045

Strand: Direct

Name: fabF [H]

Synonym: Ppro_0926

Alternate gene names: 118579363

Gene position: 975867-977045 (Clockwise)

Preceding gene: 118579362

Following gene: 118579364

Centisome position: 24.35

GC content: 68.02

Gene sequence:

>1179_bases
ATGCACGGAACCGACATGCTCATAACGGGATTGGGCGTGGTCTCGTCCGCCGGCAACGGCTGCAGCGAGACCCTTGATTC
CTTTGTACGGCTGGAACGCAACGCCGGACCGGTCACCCTCTTTCCCACGGCCATGGAGTATCCGGTCTTCGAGGTCAGGG
GGATGCCGCAACCGTATTGCCTCCAGGGGATGCGCACCCTCGGCCTGACCCTGATGGCCCTGGACCAGGCCCTGGAGGAT
GCCGGCCTGGACGACCTGTCCGGCCGACGCGTGGGGGTCTGTCTGGGGACCACGGTGGCCAGCCAGCTGAACGACCTGGG
GTTCTACGCCAGCTACCGCAGCCAGGGCTCGGCGCCTCTGACAGCGGTCGACCGCTTCCTCAAGGGGAACCTGGCCGAAT
GCGTAGCCCGCCGGGTCGGCGCACGCGGCCCGGTCCTGACCGTGGTCAACGCCTGCTCCTCGGGGAGCGATGCCATCGGC
GTGGCTCTCTCCTGGTTGAAGGGGGGGCTGTGCGACCTGGTCATCGCCGGCGGAGCCGACGAGCTGAACCATGTGCCCTA
CTGCGGCTTCAACTCCCTGGGCATCCTCAATCCGGGGCTCTGCGCCCCCTTTGACCGTGACCGCCGGGGGCTGAACCTGG
GGGAAGGGGCCGGGATCATGGTCCTGGAGCAGGAACGGCACGCCCGCATGCGGGGGAAGAGCTGCCAGCTCTTCCTGGCC
GGATACGGCTCCATGGCCGATGCCTATCACCTGACCGCCCCGCGCCCCGATGGCGCCGGCCTGAGGGCGGCGCTGCACAT
GGCCCTGGCCGAGGCTGGCATCGAACCCCGGCAGGTGGCCTTCGTCAATGCCCATGGCACCGGCACCCAGGACAATGACC
TGGTGGAGGGGACGGTTATCAAGGATCTTTTCGGAGCCGGGCTGAAGCTGCTCTCAACCAAGGGGTACACCGGCCACACC
CTGGGGGCAGCCGGCGGCCTGGAGGCGGTGTTCAGCGCCTTGGCGCTGCGGGAAGGGTGGATACCGGCCAGCGCCGGATT
CGTGAACCGGGACGAGGCCATTCCCCTGGTGCCGGTGCGGGAAAAGAGCGCCATCAGCGGATGCTATGCGGTCTCCACTT
CCCTGGCCTTCGGGGGGAACAACGCGGCCATCGTCCTGGGGCGGGGAGGGAAACCATGA

Upstream 100 bases:

>100_bases
ATCCGGACATGCGTATCGTCACCATCGACCAGGGGCTTGACCTGCTGGGGATTCCGAACTTTGTGCTTGGGCAGCAGCCC
GGACGCACGGGGAAAACGAC

Downstream 100 bases:

>100_bases
ACATCCTCGGTATCGGCTCTGTTTTCAGCCGGGGAGCGGGAGTCCCGGCCCTGGAGGATGCCCTGCTCTCCGGCTGGCAG
GCGCCGTCACGGGTGGAGGA

Product: beta-ketoacyl synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MHGTDMLITGLGVVSSAGNGCSETLDSFVRLERNAGPVTLFPTAMEYPVFEVRGMPQPYCLQGMRTLGLTLMALDQALED
AGLDDLSGRRVGVCLGTTVASQLNDLGFYASYRSQGSAPLTAVDRFLKGNLAECVARRVGARGPVLTVVNACSSGSDAIG
VALSWLKGGLCDLVIAGGADELNHVPYCGFNSLGILNPGLCAPFDRDRRGLNLGEGAGIMVLEQERHARMRGKSCQLFLA
GYGSMADAYHLTAPRPDGAGLRAALHMALAEAGIEPRQVAFVNAHGTGTQDNDLVEGTVIKDLFGAGLKLLSTKGYTGHT
LGAAGGLEAVFSALALREGWIPASAGFVNRDEAIPLVPVREKSAISGCYAVSTSLAFGGNNAAIVLGRGGKP

Sequences:

>Translated_392_residues
MHGTDMLITGLGVVSSAGNGCSETLDSFVRLERNAGPVTLFPTAMEYPVFEVRGMPQPYCLQGMRTLGLTLMALDQALED
AGLDDLSGRRVGVCLGTTVASQLNDLGFYASYRSQGSAPLTAVDRFLKGNLAECVARRVGARGPVLTVVNACSSGSDAIG
VALSWLKGGLCDLVIAGGADELNHVPYCGFNSLGILNPGLCAPFDRDRRGLNLGEGAGIMVLEQERHARMRGKSCQLFLA
GYGSMADAYHLTAPRPDGAGLRAALHMALAEAGIEPRQVAFVNAHGTGTQDNDLVEGTVIKDLFGAGLKLLSTKGYTGHT
LGAAGGLEAVFSALALREGWIPASAGFVNRDEAIPLVPVREKSAISGCYAVSTSLAFGGNNAAIVLGRGGKP
>Mature_392_residues
MHGTDMLITGLGVVSSAGNGCSETLDSFVRLERNAGPVTLFPTAMEYPVFEVRGMPQPYCLQGMRTLGLTLMALDQALED
AGLDDLSGRRVGVCLGTTVASQLNDLGFYASYRSQGSAPLTAVDRFLKGNLAECVARRVGARGPVLTVVNACSSGSDAIG
VALSWLKGGLCDLVIAGGADELNHVPYCGFNSLGILNPGLCAPFDRDRRGLNLGEGAGIMVLEQERHARMRGKSCQLFLA
GYGSMADAYHLTAPRPDGAGLRAALHMALAEAGIEPRQVAFVNAHGTGTQDNDLVEGTVIKDLFGAGLKLLSTKGYTGHT
LGAAGGLEAVFSALALREGWIPASAGFVNRDEAIPLVPVREKSAISGCYAVSTSLAFGGNNAAIVLGRGGKP

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=280, Percent_Identity=35, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI223972627, Length=150, Percent_Identity=37.3333333333333, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1787337, Length=417, Percent_Identity=31.4148681055156, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1788663, Length=405, Percent_Identity=29.8765432098765, Blast_Score=129, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71983541, Length=339, Percent_Identity=30.6784660766962, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI71983535, Length=257, Percent_Identity=31.5175097276265, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI212642053, Length=339, Percent_Identity=28.023598820059, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17550940, Length=297, Percent_Identity=27.9461279461279, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6320904, Length=437, Percent_Identity=27.9176201372998, Blast_Score=147, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24644341, Length=341, Percent_Identity=33.1378299120235, Blast_Score=158, Evalue=5e-39,
Organism=Drosophila melanogaster, GI24581345, Length=332, Percent_Identity=25.6024096385542, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221330659, Length=353, Percent_Identity=26.9121813031161, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19920632, Length=353, Percent_Identity=26.3456090651558, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 40700; Mature: 40700

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGTDMLITGLGVVSSAGNGCSETLDSFVRLERNAGPVTLFPTAMEYPVFEVRGMPQPYC
CCCCCEEEEHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCEECCCCCHHH
LQGMRTLGLTLMALDQALEDAGLDDLSGRRVGVCLGTTVASQLNDLGFYASYRSQGSAPL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHEEHHCCCCCCCH
TAVDRFLKGNLAECVARRVGARGPVLTVVNACSSGSDAIGVALSWLKGGLCDLVIAGGAD
HHHHHHHCCCHHHHHHHHHCCCCCHHHEEHHCCCCCCHHHHHHHHHCCCCEEEEEECCCH
ELNHVPYCGFNSLGILNPGLCAPFDRDRRGLNLGEGAGIMVLEQERHARMRGKSCQLFLA
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHCCCCEEEEEE
GYGSMADAYHLTAPRPDGAGLRAALHMALAEAGIEPRQVAFVNAHGTGTQDNDLVEGTVI
CCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHH
KDLFGAGLKLLSTKGYTGHTLGAAGGLEAVFSALALREGWIPASAGFVNRDEAIPLVPVR
HHHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECC
EKSAISGCYAVSTSLAFGGNNAAIVLGRGGKP
CCHHHHHHHEEHEEEEECCCCEEEEEECCCCC
>Mature Secondary Structure
MHGTDMLITGLGVVSSAGNGCSETLDSFVRLERNAGPVTLFPTAMEYPVFEVRGMPQPYC
CCCCCEEEEHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCEECCCCCHHH
LQGMRTLGLTLMALDQALEDAGLDDLSGRRVGVCLGTTVASQLNDLGFYASYRSQGSAPL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHEEHHCCCCCCCH
TAVDRFLKGNLAECVARRVGARGPVLTVVNACSSGSDAIGVALSWLKGGLCDLVIAGGAD
HHHHHHHCCCHHHHHHHHHCCCCCHHHEEHHCCCCCCHHHHHHHHHCCCCEEEEEECCCH
ELNHVPYCGFNSLGILNPGLCAPFDRDRRGLNLGEGAGIMVLEQERHARMRGKSCQLFLA
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHCCCCEEEEEE
GYGSMADAYHLTAPRPDGAGLRAALHMALAEAGIEPRQVAFVNAHGTGTQDNDLVEGTVI
CCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHH
KDLFGAGLKLLSTKGYTGHTLGAAGGLEAVFSALALREGWIPASAGFVNRDEAIPLVPVR
HHHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECC
EKSAISGCYAVSTSLAFGGNNAAIVLGRGGKP
CCHHHHHHHEEHEEEEECCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]