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The map label for this gene is fabF [H]

Identifier: 118579354

GI number: 118579354

Start: 968056

End: 969198

Strand: Direct

Name: fabF [H]

Synonym: Ppro_0917

Alternate gene names: 118579354

Gene position: 968056-969198 (Clockwise)

Preceding gene: 118579353

Following gene: 118579355

Centisome position: 24.15

GC content: 67.72

Gene sequence:

>1143_bases
ATGCCCATGAAAGCCGTTGTTGTCGACTGCGATTGCCTGACCCCCTACGGCATGGGGAGCGATGCCTGCTGGCAGGGACT
CCTGTCCGGGAGGTCGGCCATCACCAGGATTTCCCGCTTCGCCACCGGTGCCTTCATGTCCGACTACGCCGCCACGGTGG
AAGGGCTTATCTACCACGGCGGGACATCGTTGGTCATGCAGATGATCGATCGCCTGTTTCGCTGCGCTGCCCCGGACATC
CCGGCCGACAGCCGGCTCCTGCTGGCAACCACCAAGGGGGAGATCGACTTCCTGGAGATGAGCGTGCTCTCCGATAGCGG
CGATGCCGGCGAGAGCTCCCTGGAGCGGCTGCTGGAGAAGGTCGCCCGGCGCAGCGGCGCCGGGGGGGGGAGTCTGCTGC
TGTCGGCCGCCTGCACCTCGTCCTCGGCTGCAGCGGCGCGGGGCGCGGCCCTGATCAGGGATGGCCAGGCAGACTGCGTG
CTGGTGGTGGCCTGCGACGCGGTCACGGAATTCGTCTTTTCCGGCTTCTCCTCGCTGATGGCGCTGGACAGGGAGCCCGC
CCGTCCCTTCGACAAGAACCGCGCCGGACTGAGCGTGGGGGAGGCGGCCGCCTACATGCTGATCATGAGCGAAGAACGGG
CCCAACGGGAGAAGCGCGCCATCCTGGCCGAACTGGCCGGCTGGGGGTTGAGCGACGATGCCAACCACATGACCGGGCCG
AGCCGGGAAAGCGAGGGGATGATCCGCGCCATAGAGGTTGCGCTCCGCTCCGCCGGCCTGGGAGAGGAACGCATCGGTTT
CATCTCCGCCCACGGCACCGGCACCCCCTACAACGACGCCATGGAGATGCGCGCCTTCCGCGCCCTGTTCGGCGCACAGA
AGCGGCCGGTCTACTCAATCAAGGGGGGGATCGGCCACACCATGGGGGCAGCCGGTCTGGTGGAGCTGATCATGGCTGCC
AGGGCATTGAGCGAGCAGCAGGTTCCCCCCACGCTGAACCTGGAGCAGGCGAGTGACGATGCCAGGGGGTGGGTCTCCGC
CCAGCCGCAAGGACTGGAGGCGGCCGGCTATGCCCTGGTGACCAATGCCGGCTTCAGCGGCGTGAACACCGCCCTGGTGC
TGGGGAACGGGGGCCTGTCATGA

Upstream 100 bases:

>100_bases
TCCAGCTCTTTACCGACCAGCTGAGCGGTCAGCCCTGCATGGTCACGCCGGCCATGCTGGAGCGCTGCCGGAGCAGGTGG
AAGGCGGGGGAGTTTCATCC

Downstream 100 bases:

>100_bases
GAATCCAGGTGACCGGCGCCGGATGGGTGACAGAGTCGGCATACGGCAGCGTTGCGAGCGGGGAGGAGCGGCGTTTCGCC
GAGGGGGAGGGAGTAGTTTC

Product: beta-ketoacyl synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MPMKAVVVDCDCLTPYGMGSDACWQGLLSGRSAITRISRFATGAFMSDYAATVEGLIYHGGTSLVMQMIDRLFRCAAPDI
PADSRLLLATTKGEIDFLEMSVLSDSGDAGESSLERLLEKVARRSGAGGGSLLLSAACTSSSAAAARGAALIRDGQADCV
LVVACDAVTEFVFSGFSSLMALDREPARPFDKNRAGLSVGEAAAYMLIMSEERAQREKRAILAELAGWGLSDDANHMTGP
SRESEGMIRAIEVALRSAGLGEERIGFISAHGTGTPYNDAMEMRAFRALFGAQKRPVYSIKGGIGHTMGAAGLVELIMAA
RALSEQQVPPTLNLEQASDDARGWVSAQPQGLEAAGYALVTNAGFSGVNTALVLGNGGLS

Sequences:

>Translated_380_residues
MPMKAVVVDCDCLTPYGMGSDACWQGLLSGRSAITRISRFATGAFMSDYAATVEGLIYHGGTSLVMQMIDRLFRCAAPDI
PADSRLLLATTKGEIDFLEMSVLSDSGDAGESSLERLLEKVARRSGAGGGSLLLSAACTSSSAAAARGAALIRDGQADCV
LVVACDAVTEFVFSGFSSLMALDREPARPFDKNRAGLSVGEAAAYMLIMSEERAQREKRAILAELAGWGLSDDANHMTGP
SRESEGMIRAIEVALRSAGLGEERIGFISAHGTGTPYNDAMEMRAFRALFGAQKRPVYSIKGGIGHTMGAAGLVELIMAA
RALSEQQVPPTLNLEQASDDARGWVSAQPQGLEAAGYALVTNAGFSGVNTALVLGNGGLS
>Mature_379_residues
PMKAVVVDCDCLTPYGMGSDACWQGLLSGRSAITRISRFATGAFMSDYAATVEGLIYHGGTSLVMQMIDRLFRCAAPDIP
ADSRLLLATTKGEIDFLEMSVLSDSGDAGESSLERLLEKVARRSGAGGGSLLLSAACTSSSAAAARGAALIRDGQADCVL
VVACDAVTEFVFSGFSSLMALDREPARPFDKNRAGLSVGEAAAYMLIMSEERAQREKRAILAELAGWGLSDDANHMTGPS
RESEGMIRAIEVALRSAGLGEERIGFISAHGTGTPYNDAMEMRAFRALFGAQKRPVYSIKGGIGHTMGAAGLVELIMAAR
ALSEQQVPPTLNLEQASDDARGWVSAQPQGLEAAGYALVTNAGFSGVNTALVLGNGGLS

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=266, Percent_Identity=36.0902255639098, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI223972627, Length=147, Percent_Identity=40.1360544217687, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1787337, Length=256, Percent_Identity=35.546875, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1788663, Length=248, Percent_Identity=25.4032258064516, Blast_Score=91, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI71983541, Length=399, Percent_Identity=27.8195488721804, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71983535, Length=257, Percent_Identity=32.295719844358, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17550940, Length=260, Percent_Identity=25, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI212642053, Length=262, Percent_Identity=26.3358778625954, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320904, Length=254, Percent_Identity=34.251968503937, Blast_Score=126, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24644341, Length=271, Percent_Identity=33.5793357933579, Blast_Score=134, Evalue=9e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 39719; Mature: 39587

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS01186 EGF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMKAVVVDCDCLTPYGMGSDACWQGLLSGRSAITRISRFATGAFMSDYAATVEGLIYHG
CCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
GTSLVMQMIDRLFRCAAPDIPADSRLLLATTKGEIDFLEMSVLSDSGDAGESSLERLLEK
CHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHH
VARRSGAGGGSLLLSAACTSSSAAAARGAALIRDGQADCVLVVACDAVTEFVFSGFSSLM
HHHHCCCCCCHHHEEHHHCCCHHHHHHCHHHEECCCCCEEEEEEHHHHHHHHHHHHHHHH
ALDREPARPFDKNRAGLSVGEAAAYMLIMSEERAQREKRAILAELAGWGLSDDANHMTGP
HHCCCCCCCCCCCCCCCCHHHHHHEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
SRESEGMIRAIEVALRSAGLGEERIGFISAHGTGTPYNDAMEMRAFRALFGAQKRPVYSI
CCCCCHHHHHHHHHHHHCCCCHHHCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEE
KGGIGHTMGAAGLVELIMAARALSEQQVPPTLNLEQASDDARGWVSAQPQGLEAAGYALV
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCEEEE
TNAGFSGVNTALVLGNGGLS
ECCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
PMKAVVVDCDCLTPYGMGSDACWQGLLSGRSAITRISRFATGAFMSDYAATVEGLIYHG
CCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
GTSLVMQMIDRLFRCAAPDIPADSRLLLATTKGEIDFLEMSVLSDSGDAGESSLERLLEK
CHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHH
VARRSGAGGGSLLLSAACTSSSAAAARGAALIRDGQADCVLVVACDAVTEFVFSGFSSLM
HHHHCCCCCCHHHEEHHHCCCHHHHHHCHHHEECCCCCEEEEEEHHHHHHHHHHHHHHHH
ALDREPARPFDKNRAGLSVGEAAAYMLIMSEERAQREKRAILAELAGWGLSDDANHMTGP
HHCCCCCCCCCCCCCCCCHHHHHHEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
SRESEGMIRAIEVALRSAGLGEERIGFISAHGTGTPYNDAMEMRAFRALFGAQKRPVYSI
CCCCCHHHHHHHHHHHHCCCCHHHCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEE
KGGIGHTMGAAGLVELIMAARALSEQQVPPTLNLEQASDDARGWVSAQPQGLEAAGYALV
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCEEEE
TNAGFSGVNTALVLGNGGLS
ECCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]