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The map label for this gene is cobQ [H]

Identifier: 118579308

GI number: 118579308

Start: 914198

End: 916531

Strand: Reverse

Name: cobQ [H]

Synonym: Ppro_0871

Alternate gene names: 118579308

Gene position: 916531-914198 (Counterclockwise)

Preceding gene: 118579309

Following gene: 118579307

Centisome position: 22.87

GC content: 64.1

Gene sequence:

>2334_bases
ATGGCATCACTCTATATTATTGGTAGCGGTCCCGGGGCCGTTGAACACCTCACCGACGCCGCACGACAGGCCATTGCCGC
GTCAACGGTCATCGTCGGTTACGACAACTATATCGAGCAGATCAGGTCGCTCATCCAGGACAGGCAGACCGTCGCCACCG
GAATGATGCGCGAGGTTGAGCGCTGCCGCGAGGCCATCCACAGGGCACGCCAAGGAGAGACTGTCTGCCTGGTCTCGGGT
GGCGACGCAGGCATTTACGGCATGGCAGGACTGGTATTCGAACTACTGGAAAGCGAGACAACTGCGGATGCCGCGGCACC
CCAGCCGGACGTACGGGTCATCCCCGGCATCTCGGCCGTCCAGGCGGCGGCATCGGTCCTGGGCGCCCCGCTGATGCACG
ACTTCTCGGTCATCTCCCTCTCCGACCTGCTAACCCCCTGGGAGCTGATCCGCTGCAGACTGGAAGCCGCGGCACGGGCG
GACTTCGTCATCGCCCTCTACAACCCGCGCAGCAAGAGCCGCGTCACCCAGATCGAAGAGGCGGCCAGGATCATCCTGGC
CTCCCGCCCACCCGAGACGCCTGCCGGCATCGTCCGCAACGCCTGCCGACATGACCAGAACGCCACGGTCACCACCCTGG
GAGAACTGCTGAGCCACGACATCGACATGTCCACCATCGTGATCATCGGCAATGCCAGTAGCTTCATCGACAGCCGGGGC
CGCATGGTGACGCCGCGCGGCTATGCCCGCAAGTACGTCGACGCAGCCTCACCGCTGACGGCAACGCCACCGGACGGGCC
GCTCCCCGACGGACGGGCGCTGATGTTCTGCGGCACCGCATCGGATGTGGGCAAATCCATCCTCACCGCCGGCTTCTGCC
GTTCCCTGATCAGACGCGGCCTGACCGTGGCCCCCTTCAAGTCCCAGAACATGTCCAACAACTCCTTCGTCACCGCCGAG
GGGGGCGAGGTGGGGCGCGCCCAGGCCATGCAGGCCCAGGCCTGCAACATCCCGCCCCACACCGACATGAATCCGGTGCT
GCTCAAGCCCAACTCCGACACCGGCAGCCAGGTCGTCGTGCAGGGACGGCCGGTGGCCAACATGAACGTACGGGAATACG
ACAGCTACAAGCCCCAGGCTCTGGAGAGAATCAGAGAGAGCTTCCAGAACCTGCGCCAGGCCTACGAATTCATCGTCCTG
GAGGGGGCCGGCAGCATCTCCGAGATCAACCTCAAGGACAACGACATCGCCAACCTTAAGATCGCCCTGATGGCCCGCTG
CCCGGTGATCCTGGTGGCCGACATCGACCGGGGCGGCGTGTTCGCCCAGATCGCCGGCACCCTGGACCTGCTGGACCCCC
TGGAGCGGTACTACATCAAGGGGGTGATCATCAACAAGTTCCGCGGCGACGCTTCAATCCTGACCCCGGGCATCGACTTC
ATCCAGGAGCGCACCGGCGTGCCGGTGCTGGGGGTGCTCCCCTGGCTGTCCGAACTCTGCCTGCCGGCCGAGGACAGCGT
CATCCTCAGCCAGGAGGCCAAAATGGCGGCCCAGAAGGATGGCCGACAGATCAGGATCGGCATCATCCGACTGCCGCGCA
TTTCCAACTTCACCGATTTCGACCAGCTGCATGCCGAAGCAGATGTGATCCTGAGTTACGTCCGCAAGCCGGAACAGCTG
GAGGAACTGGACGTCCTGATCATCCCGGGGAGCAAATCCACCATCGGAGACCTGCTCTTCCTCAAAGAAGAGGGACTCCT
CGATGCCATCGCCGCCTTCAGGGGGCGGATCATCGGCATCTGCGGGGGCTACCAGATGCTGGGTCAACGGGTACTGGACC
CCCAGCGGGTGGAATCGTCCCTGCCCGAGGCCGAGGGTTTAGCCCTGCTGCCGGTGGAGACTACCATGCTGTTGGACAAG
GAGACCCACCAGGCCTGGGCACGCCTGGAACAGCCGGGACGGGCCATCGCCCCCGATTGCGACGGCGAGCTCAGCGGATA
CGAGATTCACATGGGAAGAACGGATTACCTCCATACCCCCCGTCCCTTTGCCCGCATCTTCCGGCGCGGTGACAGCGACG
TGGATATCCAGGACGGTTGCGTCTCGCAAGGCGGCCGGGTCTTCGGCACCTATCTGCACGGCATCTTCGACAACGCCCGC
TTCCGGGACAGCTATCTGAACGCAATCAGGAGCGAAAAGGGGATGCCGCTGCAACGGGAGGAGACTCGCCAGCCTGTCAG
CGACCCCTTCGACCTGCTCTCCTGCCACATGGAGCGGCATCTGGACATGCCGAAGCTGCTGGAAATCTGCGGACTGCCCC
GTGATCCAGCCTGA

Upstream 100 bases:

>100_bases
CATCCCCACAAGCTGACGTGTCATAATTCGTCGATTTTTCCCTCCCAGCCGATCGTTTGCACACGAACAGGACCCACACT
TCGCGCACAGAAGGAACAGC

Downstream 100 bases:

>100_bases
CCCCACCGTCCTGGCCCTGGCGCTGCTGCTGGACCTGTGCCTGGGTGATCCGCGCTGGCTGCCCCACCCGGTGGTGATGA
TCGGACGCCTGATCACCTTC

Product: cobyric acid synthase CobQ

Products: ADP; phosphate; adenosylcobyric acid; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 777; Mature: 776

Protein sequence:

>777_residues
MASLYIIGSGPGAVEHLTDAARQAIAASTVIVGYDNYIEQIRSLIQDRQTVATGMMREVERCREAIHRARQGETVCLVSG
GDAGIYGMAGLVFELLESETTADAAAPQPDVRVIPGISAVQAAASVLGAPLMHDFSVISLSDLLTPWELIRCRLEAAARA
DFVIALYNPRSKSRVTQIEEAARIILASRPPETPAGIVRNACRHDQNATVTTLGELLSHDIDMSTIVIIGNASSFIDSRG
RMVTPRGYARKYVDAASPLTATPPDGPLPDGRALMFCGTASDVGKSILTAGFCRSLIRRGLTVAPFKSQNMSNNSFVTAE
GGEVGRAQAMQAQACNIPPHTDMNPVLLKPNSDTGSQVVVQGRPVANMNVREYDSYKPQALERIRESFQNLRQAYEFIVL
EGAGSISEINLKDNDIANLKIALMARCPVILVADIDRGGVFAQIAGTLDLLDPLERYYIKGVIINKFRGDASILTPGIDF
IQERTGVPVLGVLPWLSELCLPAEDSVILSQEAKMAAQKDGRQIRIGIIRLPRISNFTDFDQLHAEADVILSYVRKPEQL
EELDVLIIPGSKSTIGDLLFLKEEGLLDAIAAFRGRIIGICGGYQMLGQRVLDPQRVESSLPEAEGLALLPVETTMLLDK
ETHQAWARLEQPGRAIAPDCDGELSGYEIHMGRTDYLHTPRPFARIFRRGDSDVDIQDGCVSQGGRVFGTYLHGIFDNAR
FRDSYLNAIRSEKGMPLQREETRQPVSDPFDLLSCHMERHLDMPKLLEICGLPRDPA

Sequences:

>Translated_777_residues
MASLYIIGSGPGAVEHLTDAARQAIAASTVIVGYDNYIEQIRSLIQDRQTVATGMMREVERCREAIHRARQGETVCLVSG
GDAGIYGMAGLVFELLESETTADAAAPQPDVRVIPGISAVQAAASVLGAPLMHDFSVISLSDLLTPWELIRCRLEAAARA
DFVIALYNPRSKSRVTQIEEAARIILASRPPETPAGIVRNACRHDQNATVTTLGELLSHDIDMSTIVIIGNASSFIDSRG
RMVTPRGYARKYVDAASPLTATPPDGPLPDGRALMFCGTASDVGKSILTAGFCRSLIRRGLTVAPFKSQNMSNNSFVTAE
GGEVGRAQAMQAQACNIPPHTDMNPVLLKPNSDTGSQVVVQGRPVANMNVREYDSYKPQALERIRESFQNLRQAYEFIVL
EGAGSISEINLKDNDIANLKIALMARCPVILVADIDRGGVFAQIAGTLDLLDPLERYYIKGVIINKFRGDASILTPGIDF
IQERTGVPVLGVLPWLSELCLPAEDSVILSQEAKMAAQKDGRQIRIGIIRLPRISNFTDFDQLHAEADVILSYVRKPEQL
EELDVLIIPGSKSTIGDLLFLKEEGLLDAIAAFRGRIIGICGGYQMLGQRVLDPQRVESSLPEAEGLALLPVETTMLLDK
ETHQAWARLEQPGRAIAPDCDGELSGYEIHMGRTDYLHTPRPFARIFRRGDSDVDIQDGCVSQGGRVFGTYLHGIFDNAR
FRDSYLNAIRSEKGMPLQREETRQPVSDPFDLLSCHMERHLDMPKLLEICGLPRDPA
>Mature_776_residues
ASLYIIGSGPGAVEHLTDAARQAIAASTVIVGYDNYIEQIRSLIQDRQTVATGMMREVERCREAIHRARQGETVCLVSGG
DAGIYGMAGLVFELLESETTADAAAPQPDVRVIPGISAVQAAASVLGAPLMHDFSVISLSDLLTPWELIRCRLEAAARAD
FVIALYNPRSKSRVTQIEEAARIILASRPPETPAGIVRNACRHDQNATVTTLGELLSHDIDMSTIVIIGNASSFIDSRGR
MVTPRGYARKYVDAASPLTATPPDGPLPDGRALMFCGTASDVGKSILTAGFCRSLIRRGLTVAPFKSQNMSNNSFVTAEG
GEVGRAQAMQAQACNIPPHTDMNPVLLKPNSDTGSQVVVQGRPVANMNVREYDSYKPQALERIRESFQNLRQAYEFIVLE
GAGSISEINLKDNDIANLKIALMARCPVILVADIDRGGVFAQIAGTLDLLDPLERYYIKGVIINKFRGDASILTPGIDFI
QERTGVPVLGVLPWLSELCLPAEDSVILSQEAKMAAQKDGRQIRIGIIRLPRISNFTDFDQLHAEADVILSYVRKPEQLE
ELDVLIIPGSKSTIGDLLFLKEEGLLDAIAAFRGRIIGICGGYQMLGQRVLDPQRVESSLPEAEGLALLPVETTMLLDKE
THQAWARLEQPGRAIAPDCDGELSGYEIHMGRTDYLHTPRPFARIFRRGDSDVDIQDGCVSQGGRVFGTYLHGIFDNARF
RDSYLNAIRSEKGMPLQREETRQPVSDPFDLLSCHMERHLDMPKLLEICGLPRDPA

Specific function: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1492

COG function: function code H; Cobyric acid synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR017929
- InterPro:   IPR004459
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: 6.3.5.10

Molecular weight: Translated: 84864; Mature: 84733

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLYIIGSGPGAVEHLTDAARQAIAASTVIVGYDNYIEQIRSLIQDRQTVATGMMREVE
CCEEEEEECCCCHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
RCREAIHRARQGETVCLVSGGDAGIYGMAGLVFELLESETTADAAAPQPDVRVIPGISAV
HHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCHHHH
QAAASVLGAPLMHDFSVISLSDLLTPWELIRCRLEAAARADFVIALYNPRSKSRVTQIEE
HHHHHHHCCHHHHCCHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHH
AARIILASRPPETPAGIVRNACRHDQNATVTTLGELLSHDIDMSTIVIIGNASSFIDSRG
HHHEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEEECCHHHHHCCC
RMVTPRGYARKYVDAASPLTATPPDGPLPDGRALMFCGTASDVGKSILTAGFCRSLIRRG
CEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCC
LTVAPFKSQNMSNNSFVTAEGGEVGRAQAMQAQACNIPPHTDMNPVLLKPNSDTGSQVVV
CEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCEEEE
QGRPVANMNVREYDSYKPQALERIRESFQNLRQAYEFIVLEGAGSISEINLKDNDIANLK
ECCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEECCCCCCCCCEE
IALMARCPVILVADIDRGGVFAQIAGTLDLLDPLERYYIKGVIINKFRGDASILTPGIDF
EEEEECCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHEEEEEECCCCCCEECCCHHH
IQERTGVPVLGVLPWLSELCLPAEDSVILSQEAKMAAQKDGRQIRIGIIRLPRISNFTDF
HHHHCCCCEEHHHHHHHHHCCCCCCCEEECHHHHHHHHCCCCEEEEEEEECCCCCCCCCH
DQLHAEADVILSYVRKPEQLEELDVLIIPGSKSTIGDLLFLKEEGLLDAIAAFRGRIIGI
HHHHHHHHHHHHHHHCCHHHHHCCEEEECCCCCCHHHEEEEECCCHHHHHHHHCCCEEEE
CGGYQMLGQRVLDPQRVESSLPEAEGLALLPVETTMLLDKETHQAWARLEQPGRAIAPDC
ECCHHHHHHHCCCHHHHHHCCCCCCCEEEEEECCEEEECCHHHHHHHHHCCCCCCCCCCC
DGELSGYEIHMGRTDYLHTPRPFARIFRRGDSDVDIQDGCVSQGGRVFGTYLHGIFDNAR
CCCCCCEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCH
FRDSYLNAIRSEKGMPLQREETRQPVSDPFDLLSCHMERHLDMPKLLEICGLPRDPA
HHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ASLYIIGSGPGAVEHLTDAARQAIAASTVIVGYDNYIEQIRSLIQDRQTVATGMMREVE
CEEEEEECCCCHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
RCREAIHRARQGETVCLVSGGDAGIYGMAGLVFELLESETTADAAAPQPDVRVIPGISAV
HHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCHHHH
QAAASVLGAPLMHDFSVISLSDLLTPWELIRCRLEAAARADFVIALYNPRSKSRVTQIEE
HHHHHHHCCHHHHCCHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHH
AARIILASRPPETPAGIVRNACRHDQNATVTTLGELLSHDIDMSTIVIIGNASSFIDSRG
HHHEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEEECCHHHHHCCC
RMVTPRGYARKYVDAASPLTATPPDGPLPDGRALMFCGTASDVGKSILTAGFCRSLIRRG
CEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCC
LTVAPFKSQNMSNNSFVTAEGGEVGRAQAMQAQACNIPPHTDMNPVLLKPNSDTGSQVVV
CEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCEEEE
QGRPVANMNVREYDSYKPQALERIRESFQNLRQAYEFIVLEGAGSISEINLKDNDIANLK
ECCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEECCCCCCCCCEE
IALMARCPVILVADIDRGGVFAQIAGTLDLLDPLERYYIKGVIINKFRGDASILTPGIDF
EEEEECCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHEEEEEECCCCCCEECCCHHH
IQERTGVPVLGVLPWLSELCLPAEDSVILSQEAKMAAQKDGRQIRIGIIRLPRISNFTDF
HHHHCCCCEEHHHHHHHHHCCCCCCCEEECHHHHHHHHCCCCEEEEEEEECCCCCCCCCH
DQLHAEADVILSYVRKPEQLEELDVLIIPGSKSTIGDLLFLKEEGLLDAIAAFRGRIIGI
HHHHHHHHHHHHHHHCCHHHHHCCEEEECCCCCCHHHEEEEECCCHHHHHHHHCCCEEEE
CGGYQMLGQRVLDPQRVESSLPEAEGLALLPVETTMLLDKETHQAWARLEQPGRAIAPDC
ECCHHHHHHHCCCHHHHHHCCCCCCCEEEEEECCEEEECCHHHHHHHHHCCCCCCCCCCC
DGELSGYEIHMGRTDYLHTPRPFARIFRRGDSDVDIQDGCVSQGGRVFGTYLHGIFDNAR
CCCCCCEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCH
FRDSYLNAIRSEKGMPLQREETRQPVSDPFDLLSCHMERHLDMPKLLEICGLPRDPA
HHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; adenosylcobyrinic acid a,c-diamide; L-glutamine; H2O

Specific reaction: 4 ATP + adenosylcobyrinic acid a,c-diamide + 4 L-glutamine + 4 H2O = 4 ADP + 4 phosphate + adenosylcobyric acid + 4 L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA