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The map label for this gene is atpB2

Identifier: 118579285

GI number: 118579285

Start: 894693

End: 895379

Strand: Reverse

Name: atpB2

Synonym: Ppro_0848

Alternate gene names: 118579285

Gene position: 895379-894693 (Counterclockwise)

Preceding gene: 118579286

Following gene: 118579284

Centisome position: 22.34

GC content: 65.5

Gene sequence:

>687_bases
ATGCTGGAAACGACACAGGCGCTGTTCCACCTGGGGCCCCTGGCCGTGGGAACCACGGTGGTGACCACCTGGGGGATCAT
GGTCGTCCTCTCCCTTGGCGCATGGCTGGCCAGCAGACGCCTGCGCCTCGACCCAGGCCCCTTCCAGGTGGCCCTGGAGG
GGGTCGTGCAGACCATCCGCGCCGCCGTGGAAGAGGTAGTGCCGCGACGCGCCGACACCGTCTTCCCCTTCGTGGCGACC
CTCTGGCTCTTCATCGGAATCGCCAACCTCTCCAGCCTGATCCCCCGTGTCCACTCCCCCACGGCAGACCTGTCCGCCAC
AACGGCCCTGGCGCTGCTGGTGTTTTTTTCGGTGCACTGGTTCGGAATCCGCATCCAGGGGCTGCGCCCCTATCTGCGAC
ATTACCTCTCGCCGAGCCCTTTCCTGCTCCCCTTTCACGTCATCGGCGAGATCACCCGCACCCTGGCCCTGGCCGTGCGC
CTGTTCGGCAACATGATGAGCCTGGAGACCGCGGCCCTGCTGGTGCTGCTGGTGGCAGGCCTGTTCGCGCCGATCCCGCT
TTTGATGCTGCACATCGTTGAAGCCCTGGTGCAGGCCTATATCTTCGGCATGCTGACACTGGTCTACATAGCCGGCGCCA
TCCAGTCCCTGGAGGCCCGGCGCTCTCCCAAGGAGGAGGAAACATGA

Upstream 100 bases:

>100_bases
CCTGGGGCTGGTCATCGGCGGGTTCAATGCCTACCTGCTGATACGGGAGCCGTAGGGACGCAGTGCACTGCGTCCCTCAC
CCAACAAGAAGGAGCACTTC

Downstream 100 bases:

>100_bases
GCGCCCTGTTCTGGTTCGTTTTCGCATCAACGGTGGTGGCGCTGATCGCCATGGCCATCGGCATCATCGCGCCGGCAAAG
GCCATGGGGCAGGCCATCTG

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a 2; F-ATPase subunit 6 2

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MLETTQALFHLGPLAVGTTVVTTWGIMVVLSLGAWLASRRLRLDPGPFQVALEGVVQTIRAAVEEVVPRRADTVFPFVAT
LWLFIGIANLSSLIPRVHSPTADLSATTALALLVFFSVHWFGIRIQGLRPYLRHYLSPSPFLLPFHVIGEITRTLALAVR
LFGNMMSLETAALLVLLVAGLFAPIPLLMLHIVEALVQAYIFGMLTLVYIAGAIQSLEARRSPKEEET

Sequences:

>Translated_228_residues
MLETTQALFHLGPLAVGTTVVTTWGIMVVLSLGAWLASRRLRLDPGPFQVALEGVVQTIRAAVEEVVPRRADTVFPFVAT
LWLFIGIANLSSLIPRVHSPTADLSATTALALLVFFSVHWFGIRIQGLRPYLRHYLSPSPFLLPFHVIGEITRTLALAVR
LFGNMMSLETAALLVLLVAGLFAPIPLLMLHIVEALVQAYIFGMLTLVYIAGAIQSLEARRSPKEEET
>Mature_228_residues
MLETTQALFHLGPLAVGTTVVTTWGIMVVLSLGAWLASRRLRLDPGPFQVALEGVVQTIRAAVEEVVPRRADTVFPFVAT
LWLFIGIANLSSLIPRVHSPTADLSATTALALLVFFSVHWFGIRIQGLRPYLRHYLSPSPFLLPFHVIGEITRTLALAVR
LFGNMMSLETAALLVLLVAGLFAPIPLLMLHIVEALVQAYIFGMLTLVYIAGAIQSLEARRSPKEEET

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family

Homologues:

Organism=Escherichia coli, GI1790176, Length=201, Percent_Identity=28.3582089552239, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATP62_PELPD (A1AMA7)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_900535.1
- ProteinModelPortal:   A1AMA7
- SMR:   A1AMA7
- STRING:   A1AMA7
- GeneID:   4573644
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_0848
- eggNOG:   COG0356
- HOGENOM:   HBG734175
- OMA:   QAYIFGM
- PhylomeDB:   A1AMA7
- ProtClustDB:   PRK13420
- HAMAP:   MF_01393
- InterPro:   IPR000568
- InterPro:   IPR023011
- Gene3D:   G3DSA:1.20.120.220
- PANTHER:   PTHR11410
- PRINTS:   PR00123
- TIGRFAMs:   TIGR01131

Pfam domain/function: PF00119 ATP-synt_A; SSF81336 ATPase_F0_A

EC number: 3.6.3.14

Molecular weight: Translated: 24993; Mature: 24993

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x22b5d008)-; HASH(0x23783934)-; HASH(0x23399a44)-; HASH(0x22b8bf04)-; HASH(0x2343066c)-; HASH(0x237839dc)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLETTQALFHLGPLAVGTTVVTTWGIMVVLSLGAWLASRRLRLDPGPFQVALEGVVQTIR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
AAVEEVVPRRADTVFPFVATLWLFIGIANLSSLIPRVHSPTADLSATTALALLVFFSVHW
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
FGIRIQGLRPYLRHYLSPSPFLLPFHVIGEITRTLALAVRLFGNMMSLETAALLVLLVAG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFAPIPLLMLHIVEALVQAYIFGMLTLVYIAGAIQSLEARRSPKEEET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
>Mature Secondary Structure
MLETTQALFHLGPLAVGTTVVTTWGIMVVLSLGAWLASRRLRLDPGPFQVALEGVVQTIR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
AAVEEVVPRRADTVFPFVATLWLFIGIANLSSLIPRVHSPTADLSATTALALLVFFSVHW
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
FGIRIQGLRPYLRHYLSPSPFLLPFHVIGEITRTLALAVRLFGNMMSLETAALLVLLVAG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFAPIPLLMLHIVEALVQAYIFGMLTLVYIAGAIQSLEARRSPKEEET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA