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The map label for this gene is atpA2 [H]

Identifier: 118579282

GI number: 118579282

Start: 892179

End: 893681

Strand: Reverse

Name: atpA2 [H]

Synonym: Ppro_0845

Alternate gene names: 118579282

Gene position: 893681-892179 (Counterclockwise)

Preceding gene: 118579283

Following gene: 118579281

Centisome position: 22.3

GC content: 68.26

Gene sequence:

>1503_bases
ATGCCGACTGAAGCCACCCCATCCCGCTCACCCCTTAACCGGCTGGAGGCCAGGCTCGCGGGGTATCGCCCCACAACCCG
CATCAGGGAACGGGGATGCGTGCTGGCCGTGGGTGATGGTGTGGCCTGGATCGGCCGCCTTCCCTCGGCCGCCCTGGATG
AGGTCATCACCCTGGAGGAGGGGAGCCGGGCACTGGTCTTTCACCTGGGCAGGGAGCTTGTGGGCGCGATCCTGCTGCAC
CAGAGCGACCGGCTCACCGCGGGGACCGGGGCCGAGCTCTCCGGAAGCCGCCCCTCCATCCCGGCGGGAGACAGCCTGTT
GGGAAGGGTCGTAGACCCCCTGGGGAGACCGCTGGACGGCGGCGAGCCACCTGCCGACTGCATCCGCCGGGAGATCTTCG
GACCGTCGGCGCCGATCCTGGCCCGCAGCTTCGTGAACAGCCCGCTGTACACCGGCACCACCATCGTGGACACCATGATC
CCGGTGGGCCGGGGCCAGCGCCAGCTGATCATCGGCGGCTCATCCACGGGGAAAAGCTCCCTGGCCCTGGATGCGGTCAT
CAGCCAGAAGGGGAACGGCGTGCTCTGCGTCTACGTCCTGATCGGCCAGAAACGTTCCAAGGGCGTTGCCATCGTGGAGA
CGCTGCGGGAGGCCGGGGCGCTCCCCCACACCACGGTGGTGGTGGCCGAGGCGTTCGAGCTCCCCGGCCTGAAATACCTG
GCCCCCTTTGCCGGCTGCGCCCTGGCCGAGGAGTGGATGCAGCGGGGCCGGGATACCCTGATCGTCTACGACGACCTCTC
CCTGCACGCCCAGACCTACCGGGAGGTGTCCCTGATCCTGCGCCGGCCGCCGGGACGCGAGGCCTATCCCGGCGACATCT
TCTCCCTCCATGCCCGGCTCCTGGAGCGCTCCACCGTCCTGGCCGCAAGTCACGGCGGAGGGAGCATGACCGCCCTGCCG
ATCATCGAGATCCAGCAGGGGGAGTTGGCGGCCTACATCCCCACCAACCTGATCTCCATCACCGACGGCCAGATATACCT
GGACCAGCAGCTCTTCTCCGCCGGCTTCCTGCCGGCCATCGACATCACCCGCTCGGTCTCCCGCATCGGCGGCAAGGCCC
AACACCAGAGGGTCAAGGAGGAGGTGGGGCGCATGAAGCTGGACTACCTGCAGTTCCTGGAGCTGGAACTGTTCACCCGT
TTCGGCGCCCGCCTGGAGGCCTCGGTGGAGGCTCGCATCAGGCGGGGGAGGCTGCTACGGGAACTGCTGCGCCAGGAACG
GCGCGCCCCCCTTCCGGTGGAGTACCAGTTGGCCTGGCTGATCGCCTTCAACGAGGGGATGCTGGATAAAAAGAAACCGG
AGGAGATTGCGGGGGTAACGAAGAGGCTGGCAGCCGCGGTGGCCGGGAGCAGCTGCACGCTGGAGAGCGACCGCGACGCC
TGGCTGGCGCTGGTCAGTCAGGCCCTGGCAGACGACGGGGGGATGAATGGCCAGCAAGCGTGA

Upstream 100 bases:

>100_bases
GAAGACCCGACGCTTTTGGCCGGTGTGCGCGTGATCGCCGGCCCCTGGAATCTGGCTGCCAACCTGAGTGACGAACTGGC
CTTTTTCCGGGGAGGAATCG

Downstream 100 bases:

>100_bases
GCTTGAACGGCGGCTAGCCGCCCTGGGTGACATCGGCGCCATCCTGGGGGTGATGAAGAACCTGGCCCTGATGGAGACCG
CCAAGCTTTCCCGCGTGCTT

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha 2; F-ATPase subunit alpha 2 [H]

Number of amino acids: Translated: 500; Mature: 499

Protein sequence:

>500_residues
MPTEATPSRSPLNRLEARLAGYRPTTRIRERGCVLAVGDGVAWIGRLPSAALDEVITLEEGSRALVFHLGRELVGAILLH
QSDRLTAGTGAELSGSRPSIPAGDSLLGRVVDPLGRPLDGGEPPADCIRREIFGPSAPILARSFVNSPLYTGTTIVDTMI
PVGRGQRQLIIGGSSTGKSSLALDAVISQKGNGVLCVYVLIGQKRSKGVAIVETLREAGALPHTTVVVAEAFELPGLKYL
APFAGCALAEEWMQRGRDTLIVYDDLSLHAQTYREVSLILRRPPGREAYPGDIFSLHARLLERSTVLAASHGGGSMTALP
IIEIQQGELAAYIPTNLISITDGQIYLDQQLFSAGFLPAIDITRSVSRIGGKAQHQRVKEEVGRMKLDYLQFLELELFTR
FGARLEASVEARIRRGRLLRELLRQERRAPLPVEYQLAWLIAFNEGMLDKKKPEEIAGVTKRLAAAVAGSSCTLESDRDA
WLALVSQALADDGGMNGQQA

Sequences:

>Translated_500_residues
MPTEATPSRSPLNRLEARLAGYRPTTRIRERGCVLAVGDGVAWIGRLPSAALDEVITLEEGSRALVFHLGRELVGAILLH
QSDRLTAGTGAELSGSRPSIPAGDSLLGRVVDPLGRPLDGGEPPADCIRREIFGPSAPILARSFVNSPLYTGTTIVDTMI
PVGRGQRQLIIGGSSTGKSSLALDAVISQKGNGVLCVYVLIGQKRSKGVAIVETLREAGALPHTTVVVAEAFELPGLKYL
APFAGCALAEEWMQRGRDTLIVYDDLSLHAQTYREVSLILRRPPGREAYPGDIFSLHARLLERSTVLAASHGGGSMTALP
IIEIQQGELAAYIPTNLISITDGQIYLDQQLFSAGFLPAIDITRSVSRIGGKAQHQRVKEEVGRMKLDYLQFLELELFTR
FGARLEASVEARIRRGRLLRELLRQERRAPLPVEYQLAWLIAFNEGMLDKKKPEEIAGVTKRLAAAVAGSSCTLESDRDA
WLALVSQALADDGGMNGQQA
>Mature_499_residues
PTEATPSRSPLNRLEARLAGYRPTTRIRERGCVLAVGDGVAWIGRLPSAALDEVITLEEGSRALVFHLGRELVGAILLHQ
SDRLTAGTGAELSGSRPSIPAGDSLLGRVVDPLGRPLDGGEPPADCIRREIFGPSAPILARSFVNSPLYTGTTIVDTMIP
VGRGQRQLIIGGSSTGKSSLALDAVISQKGNGVLCVYVLIGQKRSKGVAIVETLREAGALPHTTVVVAEAFELPGLKYLA
PFAGCALAEEWMQRGRDTLIVYDDLSLHAQTYREVSLILRRPPGREAYPGDIFSLHARLLERSTVLAASHGGGSMTALPI
IEIQQGELAAYIPTNLISITDGQIYLDQQLFSAGFLPAIDITRSVSRIGGKAQHQRVKEEVGRMKLDYLQFLELELFTRF
GARLEASVEARIRRGRLLRELLRQERRAPLPVEYQLAWLIAFNEGMLDKKKPEEIAGVTKRLAAAVAGSSCTLESDRDAW
LALVSQALADDGGMNGQQA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=451, Percent_Identity=43.4589800443459, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI4757810, Length=451, Percent_Identity=43.4589800443459, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI32189394, Length=338, Percent_Identity=26.3313609467456, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI19913426, Length=294, Percent_Identity=24.4897959183673, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI19913428, Length=294, Percent_Identity=24.1496598639456, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1790172, Length=496, Percent_Identity=41.3306451612903, Blast_Score=356, Evalue=2e-99,
Organism=Escherichia coli, GI1788251, Length=269, Percent_Identity=30.8550185873606, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1790170, Length=325, Percent_Identity=25.5384615384615, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71988063, Length=468, Percent_Identity=42.5213675213675, Blast_Score=387, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI71988080, Length=468, Percent_Identity=42.5213675213675, Blast_Score=386, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI71988074, Length=468, Percent_Identity=39.957264957265, Blast_Score=350, Evalue=1e-96,
Organism=Caenorhabditis elegans, GI17510931, Length=298, Percent_Identity=25.503355704698, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17570191, Length=333, Percent_Identity=24.6246246246246, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI25144756, Length=310, Percent_Identity=25.1612903225806, Blast_Score=90, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319370, Length=457, Percent_Identity=44.6389496717724, Blast_Score=360, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6319603, Length=295, Percent_Identity=27.1186440677966, Blast_Score=103, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6322581, Length=309, Percent_Identity=24.9190938511327, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24658560, Length=471, Percent_Identity=42.4628450106157, Blast_Score=382, Evalue=1e-106,
Organism=Drosophila melanogaster, GI281361666, Length=300, Percent_Identity=24, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24646341, Length=300, Percent_Identity=24, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI17136796, Length=300, Percent_Identity=24, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24638766, Length=335, Percent_Identity=25.3731343283582, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28574560, Length=315, Percent_Identity=24.7619047619048, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 54034; Mature: 53903

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTEATPSRSPLNRLEARLAGYRPTTRIRERGCVLAVGDGVAWIGRLPSAALDEVITLEE
CCCCCCCCCCHHHHHHHHHCCCCCCHHHHHCCCEEEECCCHHHHHCCCHHHHHHEEEECC
GSRALVFHLGRELVGAILLHQSDRLTAGTGAELSGSRPSIPAGDSLLGRVVDPLGRPLDG
CCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCC
GEPPADCIRREIFGPSAPILARSFVNSPLYTGTTIVDTMIPVGRGQRQLIIGGSSTGKSS
CCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCH
LALDAVISQKGNGVLCVYVLIGQKRSKGVAIVETLREAGALPHTTVVVAEAFELPGLKYL
HHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEHHHCCCCCHHH
APFAGCALAEEWMQRGRDTLIVYDDLSLHAQTYREVSLILRRPPGREAYPGDIFSLHARL
HHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
LERSTVLAASHGGGSMTALPIIEIQQGELAAYIPTNLISITDGQIYLDQQLFSAGFLPAI
HHHHHEEEEECCCCCEEEEEEEEECCCCEEEECCCCEEEEECCEEEEHHHHHHCCCCCHH
DITRSVSRIGGKAQHQRVKEEVGRMKLDYLQFLELELFTRFGARLEASVEARIRRGRLLR
HHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
ELLRQERRAPLPVEYQLAWLIAFNEGMLDKKKPEEIAGVTKRLAAAVAGSSCTLESDRDA
HHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHH
WLALVSQALADDGGMNGQQA
HHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PTEATPSRSPLNRLEARLAGYRPTTRIRERGCVLAVGDGVAWIGRLPSAALDEVITLEE
CCCCCCCCCHHHHHHHHHCCCCCCHHHHHCCCEEEECCCHHHHHCCCHHHHHHEEEECC
GSRALVFHLGRELVGAILLHQSDRLTAGTGAELSGSRPSIPAGDSLLGRVVDPLGRPLDG
CCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCC
GEPPADCIRREIFGPSAPILARSFVNSPLYTGTTIVDTMIPVGRGQRQLIIGGSSTGKSS
CCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCH
LALDAVISQKGNGVLCVYVLIGQKRSKGVAIVETLREAGALPHTTVVVAEAFELPGLKYL
HHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEHHHCCCCCHHH
APFAGCALAEEWMQRGRDTLIVYDDLSLHAQTYREVSLILRRPPGREAYPGDIFSLHARL
HHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
LERSTVLAASHGGGSMTALPIIEIQQGELAAYIPTNLISITDGQIYLDQQLFSAGFLPAI
HHHHHEEEEECCCCCEEEEEEEEECCCCEEEECCCCEEEEECCEEEEHHHHHHCCCCCHH
DITRSVSRIGGKAQHQRVKEEVGRMKLDYLQFLELELFTRFGARLEASVEARIRRGRLLR
HHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
ELLRQERRAPLPVEYQLAWLIAFNEGMLDKKKPEEIAGVTKRLAAAVAGSSCTLESDRDA
HHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHH
WLALVSQALADDGGMNGQQA
HHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA