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The map label for this gene is arsB [H]

Identifier: 118579278

GI number: 118579278

Start: 888285

End: 889346

Strand: Reverse

Name: arsB [H]

Synonym: Ppro_0841

Alternate gene names: 118579278

Gene position: 889346-888285 (Counterclockwise)

Preceding gene: 118579279

Following gene: 118579277

Centisome position: 22.19

GC content: 60.17

Gene sequence:

>1062_bases
ATGAGTGAACACGTTTCCCGCAAACTGTCCTTCCTGGACCGCTGGCTGACGCTCTGGATTTTCGCCGCCATGGCGCTGGG
CGTGGGCATGGGCTTTTTCATTCCGGGCGTGGAAGCCTTCATCAACAGCTTCCAGATGGGGACCACCAACATCCCCATCG
CAGTCGGCCTGATCGTGATGATGTATCCCCCCTTTGCCAAGGTGAAGTACGAGGAAATGCCAGAGGTTTTCCAGAACAAG
AAGATCCTGGGAGTTTCGCTGGTGCAGAATTGGGTGATCGGGCCGGTGCTGATGTTCGCACTGGCGGCCCTGCTGCTGCC
GGACAAACCGGAGTACATGGTCGGCCTGATCATGATCGGTCTGGCACGCTGCATCGCCATGGTCATCGTCTGGAACGAAC
TGGCCAAGGGGAGCACCGAATACGCCGCCGGTCTGGTGGCCTTCAACAGTATCTTCCAGGTGCTCTTCTTCAGTGTCTAC
GCCTGGTTCTTCATCACGGTCCTGCCGCCCATGATCGGCCTCAAGGGAGTGGTGGTTGACGTGAGCATCGGCCAGATCGC
CGAGAGCGTCTTCATCTACCTGGGCATCCCCTGTATCGCCGGCGCCCTGACACGGCTGATCGGGGTCAAGATCATGGGCA
AGGAGCGCTACCACCGCGTGGTGGTGCCCAAGATCAGCCCTCTGACCCTGATCGCCCTGCTCTTCACCATCGTGGTCATG
TTCAGCCTGAAGGGCAACCTGATCGTACAACTCCCCATGGATGTAGTGCGCATCGCCATTCCGCTGCTGGTCTACTTCGT
GGTGATGTTCCTGGTCTCCTTCTGGATGGGCAAGCGCCTGGGCGCCGACTACTCCAGGACCACCACCCTGGCCTTCACCG
CTGCCAGCAACAACTTCGAGCTGGCCATCGCCGTGGCAATTGCCGTATTCGGGCTCAACTCCGGCGCCGCCTTTGCCGCC
GTGATCGGGCCGCTGGTGGAGGTGCCGGTGATGATCGGACTGGTCAACGTGGCCTTCTGGTTCCAGCGCAGATGGTTCGC
CGGTAGGCCCGTGATCAGTTAG

Upstream 100 bases:

>100_bases
CGTCGCGTCTCGAAGGGAGCGAGGAAGAACTGCTGCCGGAATTCCGCCGCGTGCGTGACGAGATAAAAAACTGGATAATC
CACCATTTCGGAGGTGCATC

Downstream 100 bases:

>100_bases
GATCCATGATTATCCGGCGTTTCAGCTTGAGCGTGTAAAAACGACCAAATTTCTGGCAAGATGGATTCAGAAGCACTTCA
TCTTCAGGGGAGGATGCCAT

Product: arsenical-resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MSEHVSRKLSFLDRWLTLWIFAAMALGVGMGFFIPGVEAFINSFQMGTTNIPIAVGLIVMMYPPFAKVKYEEMPEVFQNK
KILGVSLVQNWVIGPVLMFALAALLLPDKPEYMVGLIMIGLARCIAMVIVWNELAKGSTEYAAGLVAFNSIFQVLFFSVY
AWFFITVLPPMIGLKGVVVDVSIGQIAESVFIYLGIPCIAGALTRLIGVKIMGKERYHRVVVPKISPLTLIALLFTIVVM
FSLKGNLIVQLPMDVVRIAIPLLVYFVVMFLVSFWMGKRLGADYSRTTTLAFTAASNNFELAIAVAIAVFGLNSGAAFAA
VIGPLVEVPVMIGLVNVAFWFQRRWFAGRPVIS

Sequences:

>Translated_353_residues
MSEHVSRKLSFLDRWLTLWIFAAMALGVGMGFFIPGVEAFINSFQMGTTNIPIAVGLIVMMYPPFAKVKYEEMPEVFQNK
KILGVSLVQNWVIGPVLMFALAALLLPDKPEYMVGLIMIGLARCIAMVIVWNELAKGSTEYAAGLVAFNSIFQVLFFSVY
AWFFITVLPPMIGLKGVVVDVSIGQIAESVFIYLGIPCIAGALTRLIGVKIMGKERYHRVVVPKISPLTLIALLFTIVVM
FSLKGNLIVQLPMDVVRIAIPLLVYFVVMFLVSFWMGKRLGADYSRTTTLAFTAASNNFELAIAVAIAVFGLNSGAAFAA
VIGPLVEVPVMIGLVNVAFWFQRRWFAGRPVIS
>Mature_352_residues
SEHVSRKLSFLDRWLTLWIFAAMALGVGMGFFIPGVEAFINSFQMGTTNIPIAVGLIVMMYPPFAKVKYEEMPEVFQNKK
ILGVSLVQNWVIGPVLMFALAALLLPDKPEYMVGLIMIGLARCIAMVIVWNELAKGSTEYAAGLVAFNSIFQVLFFSVYA
WFFITVLPPMIGLKGVVVDVSIGQIAESVFIYLGIPCIAGALTRLIGVKIMGKERYHRVVVPKISPLTLIALLFTIVVMF
SLKGNLIVQLPMDVVRIAIPLLVYFVVMFLVSFWMGKRLGADYSRTTTLAFTAASNNFELAIAVAIAVFGLNSGAAFAAV
IGPLVEVPVMIGLVNVAFWFQRRWFAGRPVIS

Specific function: Seems to confer resistance to arsenite by allowing cells to extrude this compound. Could be part of an arsenite extrusion pump [H]

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=320, Percent_Identity=36.5625, Blast_Score=178, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 38836; Mature: 38704

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEHVSRKLSFLDRWLTLWIFAAMALGVGMGFFIPGVEAFINSFQMGTTNIPIAVGLIVM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHH
MYPPFAKVKYEEMPEVFQNKKILGVSLVQNWVIGPVLMFALAALLLPDKPEYMVGLIMIG
HCCCHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LARCIAMVIVWNELAKGSTEYAAGLVAFNSIFQVLFFSVYAWFFITVLPPMIGLKGVVVD
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
VSIGQIAESVFIYLGIPCIAGALTRLIGVKIMGKERYHRVVVPKISPLTLIALLFTIVVM
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEECCCCCHHHHHHHHHHHHHH
FSLKGNLIVQLPMDVVRIAIPLLVYFVVMFLVSFWMGKRLGADYSRTTTLAFTAASNNFE
HHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCH
LAIAVAIAVFGLNSGAAFAAVIGPLVEVPVMIGLVNVAFWFQRRWFAGRPVIS
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SEHVSRKLSFLDRWLTLWIFAAMALGVGMGFFIPGVEAFINSFQMGTTNIPIAVGLIVM
CHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHH
MYPPFAKVKYEEMPEVFQNKKILGVSLVQNWVIGPVLMFALAALLLPDKPEYMVGLIMIG
HCCCHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LARCIAMVIVWNELAKGSTEYAAGLVAFNSIFQVLFFSVYAWFFITVLPPMIGLKGVVVD
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
VSIGQIAESVFIYLGIPCIAGALTRLIGVKIMGKERYHRVVVPKISPLTLIALLFTIVVM
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEECCCCCHHHHHHHHHHHHHH
FSLKGNLIVQLPMDVVRIAIPLLVYFVVMFLVSFWMGKRLGADYSRTTTLAFTAASNNFE
HHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCH
LAIAVAIAVFGLNSGAAFAAVIGPLVEVPVMIGLVNVAFWFQRRWFAGRPVIS
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895; 9537360 [H]