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The map label for this gene is zntR [H]

Identifier: 118579268

GI number: 118579268

Start: 879320

End: 879757

Strand: Reverse

Name: zntR [H]

Synonym: Ppro_0831

Alternate gene names: 118579268

Gene position: 879757-879320 (Counterclockwise)

Preceding gene: 118579271

Following gene: 118579267

Centisome position: 21.95

GC content: 61.42

Gene sequence:

>438_bases
ATGAAAATCGGAGAACTGGCGCAACGCGGCGACTGCAGCGTGGAAACGGTACGCTTTTACGAGCGGGAGGGCCTGCTGGA
ATCGCCTGCGCGTGACAGCAACGGCTATCGCTGCTACACCGGCACCCATCTGGTGCAGCTCAACTTCATCCGCCACTGCC
GCTCGCTGGGCATGGGATTGCCGGATGTGCGCAGATTGCGCTCACTGCAGGCCCATCCCGAACAGGGCTGCGACGAGATC
AACCACTTGATCGAAAGCCAGATCGAGCGTGTCCACCAGCAGATCCGGTCACTGCACCTGCTGGAGCAGCAGTTACACGC
GCTGCGGGATACCTGTCATGCCACGACGAATGTGGGCGAATGCGGCATCCTGCGCAATCTGGAGCAGGCGGCCGAGGGGG
AGAACTGCATCTGCCATCCTCCCGACACGACAAACTGA

Upstream 100 bases:

>100_bases
GCGTAGCAGGCTTGTTCATGGTGGCGCACCTCCGAGGCTATGCTACTATTAGACAGCCTGTACCCACTTCAGGGTCAAGG
GCTTTTCGGAGAGGATTGGC

Downstream 100 bases:

>100_bases
GGCTCATCAAACGTAATCCGCGTATCAAACGGCAGCGCTGTTTCGCGAACAGACTGTTCATGGAGTACACCAGAACCAGC
CCCGCGTTCCAGCAGGGGGA

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: Zn(II)-responsive regulator of zntA [H]

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MKIGELAQRGDCSVETVRFYEREGLLESPARDSNGYRCYTGTHLVQLNFIRHCRSLGMGLPDVRRLRSLQAHPEQGCDEI
NHLIESQIERVHQQIRSLHLLEQQLHALRDTCHATTNVGECGILRNLEQAAEGENCICHPPDTTN

Sequences:

>Translated_145_residues
MKIGELAQRGDCSVETVRFYEREGLLESPARDSNGYRCYTGTHLVQLNFIRHCRSLGMGLPDVRRLRSLQAHPEQGCDEI
NHLIESQIERVHQQIRSLHLLEQQLHALRDTCHATTNVGECGILRNLEQAAEGENCICHPPDTTN
>Mature_145_residues
MKIGELAQRGDCSVETVRFYEREGLLESPARDSNGYRCYTGTHLVQLNFIRHCRSLGMGLPDVRRLRSLQAHPEQGCDEI
NHLIESQIERVHQQIRSLHLLEQQLHALRDTCHATTNVGECGILRNLEQAAEGENCICHPPDTTN

Specific function: Zinc-responsive transcriptional regulator of zntA [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=139, Percent_Identity=35.2517985611511, Blast_Score=91, Evalue=3e-20,
Organism=Escherichia coli, GI1786695, Length=127, Percent_Identity=29.9212598425197, Blast_Score=72, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358
- InterPro:   IPR011788 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 16470; Mature: 16470

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
5.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGELAQRGDCSVETVRFYEREGLLESPARDSNGYRCYTGTHLVQLNFIRHCRSLGMGL
CCCHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCC
PDVRRLRSLQAHPEQGCDEINHLIESQIERVHQQIRSLHLLEQQLHALRDTCHATTNVGE
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
CGILRNLEQAAEGENCICHPPDTTN
HHHHHHHHHHHCCCCCEECCCCCCC
>Mature Secondary Structure
MKIGELAQRGDCSVETVRFYEREGLLESPARDSNGYRCYTGTHLVQLNFIRHCRSLGMGL
CCCHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCC
PDVRRLRSLQAHPEQGCDEINHLIESQIERVHQQIRSLHLLEQQLHALRDTCHATTNVGE
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
CGILRNLEQAAEGENCICHPPDTTN
HHHHHHHHHHHCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]