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The map label for this gene is virA [H]

Identifier: 118579178

GI number: 118579178

Start: 778385

End: 780481

Strand: Direct

Name: virA [H]

Synonym: Ppro_0740

Alternate gene names: 118579178

Gene position: 778385-780481 (Clockwise)

Preceding gene: 118579177

Following gene: 118579179

Centisome position: 19.42

GC content: 59.94

Gene sequence:

>2097_bases
ATGTCACGGTTTCCTTCTGTCATGAGCAAGCGCATCCTGATCCTGGTCATTCTGGTGACGGTTGTCTTTGTGGGGAAAGT
CCTCTTCGACATCACCTCTGACTACGGGCAGGTCATCCTTTCCGCGGAACGCCTGTCTCGCGGATTCGCCACCGCGCTCA
ACGAGCATGCCGTATACACGTTCAGCAACGCGGAAAACACCCTGGACGACCTCATCCAACATCTTCAGGAGCGCTCGTCC
CGCGCCATGCCCGATGAACGCCAGTTGCATCGCCTCCTCGTCAACTACCGGCTGAAGAGCCCCAACAGCCCCTTCCTCTT
CGCGACCACCGCTGGCGGCCGCCTCCACGCTTCTTCATCCGATTTTCCGGTCCGCGGCCTCAACCTCGTCAACCGCGAGT
ATTTCCAGCACCACCTGAACAGCCGGGATACTGCCCCGTATATCAGTCGATCTCCCAACAGCCTGATAGACGGCGACTGG
CTCATTTTCCTGACCAAGCGGATCTCCAATCCGGACGGCTCGCTGCGCATGATTGTGGGTATATCCATCGACCCGCTCCA
TTTGAATGATTTCTACCGCTCCATCGAACTGGGCACCCATGACCGGATTTTCCTGTTCCGCAAGGACGGTGCCGTCCTGA
CCCTGGAACCGTTCTATAAGGCGTTCATGGATAAGATCATTCCACCAACGGATACGATCAGGAGAGAGCTTGCCAAGCGT
CCCCATGCCGGCACCATCCATATGGAACAGGGGCTTGTGGATGAAACCAGCAGGATCGTGTCCTATCGCTTCTCGAACCG
TTATCCGGTGGTCTCCGTCGTTTCGCTGCGGGAGGATGATGTGCTGGCGCGCTGGAGAGCGCGTTCCGCCAAGAGTGCCG
CCGGGGCGCTGCTGCTGGTCGTGCTGGTGGGGACGCTGGGACTGCTGGTCTATCGTCAGGTCAAGGCGCTGAAGCAGAGT
GAAGACAAGTACAGCCTGATCTCCACCACCGCCAACGAGGGGATCTGGATGCTGGATGCAGACGACCGCATCATCTATGT
CAATCCCCGCGTGGGGGAGATGTTCGGCTATCCCGGCGAGGAGATGGTTGGGCATCCGATAAGCTCGTTCATGTGTCCGG
ACCAGCTTGCCGACCATGAAGTTCGGATGAGGTTCCGCAAAGAGGGGGGCTCCGAACGCTATGAGCGCCGCTTCCAGCAC
AGAGATGGCAGGGATGTCTGGACAATCATCTCAGCCGCGGCACTCATCGACGACGAGGATGGTTATCAGGGGGTCGTGGC
CATGTGCCTCGACATCACTGACCGCAAAATGAGCGAGGAACGCCAGACCCGGCTGGAAGAACAGTTGCGCCAGGCCCATA
AGATGGAGGCGGTGGGCATTCTGGCAGGTGGCATGGCCCACGATTTCAATAACCTGCTCCAGTCCATCATGGGATACATC
TTCCTGGCCAGGATGAGCGTGGAAGCCGACAGCGAGGCACGGGAATATCTGGACGAGGCGGAGAAGATCTCCGGCCAGGC
CAGCGAGCTGGGACAGCGGCTCCTGCTCCTTTCCCGCGGAGGAGTCGCCCTGTTGCGCGCCGCCCCCCTGGCGCCACTGA
TCCTGCCGCTGGTTTCCTCCGAGCTGGAGGGGACTGCCATCACCGGCGAGTTCGATCTGCCGGATGACATGCCGCACGTC
ACCATGGATGAGGCGCTGATGAAGCAGGTCATATCGCACCTGACGGTCAATGCCGTCGAAACCATGCCCGAGGGGGGCAC
GCTGCGCATCACCGGCGCAACGTTGACCATCACGGCAAAAAACGGGCTACCGCTTCCCGCCGGCCGCTACGTTCATATCG
CCTTCAGCGATACGGGGGGCGGGATTCCCGCCGACAATCTGCCCAGGATTTTCGATCCCTACTTCACCACCAAGGAGATG
TGGAACCGCAAGGGCATGGGGCTCGGTCTGGCCCTCTGCCATACGATCATACGCAAGCACAAAGGAATGATCAGCGCCAC
GTCGCCTGTGGGGGAAGGGGCCACGTTCAATATCTACCTTCCGGTCGCAGGCGAGGATGCCCCGACTCCATTCTCCGCAC
CCCCTCAGTTCTTCTGA

Upstream 100 bases:

>100_bases
TAGGTAAATGGCTGTTTCCCCCATTATTTGTCATGTAGTTTCCGTCCCCCCCTTCATACAGAGACTTGAATAATGGAATG
TGATTGTCACGAGGGCGTTA

Downstream 100 bases:

>100_bases
GCTCGTAAAGGTCTCCTGTTCCATGCGCGTTATCCTCGTTGCCATCCATCCCTATCCATCTCCTCAGGCTGTCCCTCTGG
CCAATGGTTTTCTTGCCGCC

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: WHR virA [H]

Number of amino acids: Translated: 698; Mature: 697

Protein sequence:

>698_residues
MSRFPSVMSKRILILVILVTVVFVGKVLFDITSDYGQVILSAERLSRGFATALNEHAVYTFSNAENTLDDLIQHLQERSS
RAMPDERQLHRLLVNYRLKSPNSPFLFATTAGGRLHASSSDFPVRGLNLVNREYFQHHLNSRDTAPYISRSPNSLIDGDW
LIFLTKRISNPDGSLRMIVGISIDPLHLNDFYRSIELGTHDRIFLFRKDGAVLTLEPFYKAFMDKIIPPTDTIRRELAKR
PHAGTIHMEQGLVDETSRIVSYRFSNRYPVVSVVSLREDDVLARWRARSAKSAAGALLLVVLVGTLGLLVYRQVKALKQS
EDKYSLISTTANEGIWMLDADDRIIYVNPRVGEMFGYPGEEMVGHPISSFMCPDQLADHEVRMRFRKEGGSERYERRFQH
RDGRDVWTIISAAALIDDEDGYQGVVAMCLDITDRKMSEERQTRLEEQLRQAHKMEAVGILAGGMAHDFNNLLQSIMGYI
FLARMSVEADSEAREYLDEAEKISGQASELGQRLLLLSRGGVALLRAAPLAPLILPLVSSELEGTAITGEFDLPDDMPHV
TMDEALMKQVISHLTVNAVETMPEGGTLRITGATLTITAKNGLPLPAGRYVHIAFSDTGGGIPADNLPRIFDPYFTTKEM
WNRKGMGLGLALCHTIIRKHKGMISATSPVGEGATFNIYLPVAGEDAPTPFSAPPQFF

Sequences:

>Translated_698_residues
MSRFPSVMSKRILILVILVTVVFVGKVLFDITSDYGQVILSAERLSRGFATALNEHAVYTFSNAENTLDDLIQHLQERSS
RAMPDERQLHRLLVNYRLKSPNSPFLFATTAGGRLHASSSDFPVRGLNLVNREYFQHHLNSRDTAPYISRSPNSLIDGDW
LIFLTKRISNPDGSLRMIVGISIDPLHLNDFYRSIELGTHDRIFLFRKDGAVLTLEPFYKAFMDKIIPPTDTIRRELAKR
PHAGTIHMEQGLVDETSRIVSYRFSNRYPVVSVVSLREDDVLARWRARSAKSAAGALLLVVLVGTLGLLVYRQVKALKQS
EDKYSLISTTANEGIWMLDADDRIIYVNPRVGEMFGYPGEEMVGHPISSFMCPDQLADHEVRMRFRKEGGSERYERRFQH
RDGRDVWTIISAAALIDDEDGYQGVVAMCLDITDRKMSEERQTRLEEQLRQAHKMEAVGILAGGMAHDFNNLLQSIMGYI
FLARMSVEADSEAREYLDEAEKISGQASELGQRLLLLSRGGVALLRAAPLAPLILPLVSSELEGTAITGEFDLPDDMPHV
TMDEALMKQVISHLTVNAVETMPEGGTLRITGATLTITAKNGLPLPAGRYVHIAFSDTGGGIPADNLPRIFDPYFTTKEM
WNRKGMGLGLALCHTIIRKHKGMISATSPVGEGATFNIYLPVAGEDAPTPFSAPPQFF
>Mature_697_residues
SRFPSVMSKRILILVILVTVVFVGKVLFDITSDYGQVILSAERLSRGFATALNEHAVYTFSNAENTLDDLIQHLQERSSR
AMPDERQLHRLLVNYRLKSPNSPFLFATTAGGRLHASSSDFPVRGLNLVNREYFQHHLNSRDTAPYISRSPNSLIDGDWL
IFLTKRISNPDGSLRMIVGISIDPLHLNDFYRSIELGTHDRIFLFRKDGAVLTLEPFYKAFMDKIIPPTDTIRRELAKRP
HAGTIHMEQGLVDETSRIVSYRFSNRYPVVSVVSLREDDVLARWRARSAKSAAGALLLVVLVGTLGLLVYRQVKALKQSE
DKYSLISTTANEGIWMLDADDRIIYVNPRVGEMFGYPGEEMVGHPISSFMCPDQLADHEVRMRFRKEGGSERYERRFQHR
DGRDVWTIISAAALIDDEDGYQGVVAMCLDITDRKMSEERQTRLEEQLRQAHKMEAVGILAGGMAHDFNNLLQSIMGYIF
LARMSVEADSEAREYLDEAEKISGQASELGQRLLLLSRGGVALLRAAPLAPLILPLVSSELEGTAITGEFDLPDDMPHVT
MDEALMKQVISHLTVNAVETMPEGGTLRITGATLTITAKNGLPLPAGRYVHIAFSDTGGGIPADNLPRIFDPYFTTKEMW
NRKGMGLGLALCHTIIRKHKGMISATSPVGEGATFNIYLPVAGEDAPTPFSAPPQFF

Specific function: Activates virG, by phosphorylating it, in the presence of acetosyringone or hydroxysyringone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=385, Percent_Identity=27.7922077922078, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI1790436, Length=255, Percent_Identity=34.1176470588235, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI145693157, Length=156, Percent_Identity=34.6153846153846, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1788393, Length=136, Percent_Identity=30.8823529411765, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 77867; Mature: 77736

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRFPSVMSKRILILVILVTVVFVGKVLFDITSDYGQVILSAERLSRGFATALNEHAVYT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
FSNAENTLDDLIQHLQERSSRAMPDERQLHRLLVNYRLKSPNSPFLFATTAGGRLHASSS
ECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEECCCCCCEEEEEECCCEEECCCC
DFPVRGLNLVNREYFQHHLNSRDTAPYISRSPNSLIDGDWLIFLTKRISNPDGSLRMIVG
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHCCCCCCEEEEEE
ISIDPLHLNDFYRSIELGTHDRIFLFRKDGAVLTLEPFYKAFMDKIIPPTDTIRRELAKR
EEECCEEHHHHHHHHCCCCCCEEEEEECCCCEEEEHHHHHHHHHHCCCCHHHHHHHHHHC
PHAGTIHMEQGLVDETSRIVSYRFSNRYPVVSVVSLREDDVLARWRARSAKSAAGALLLV
CCCCEEECCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHCCHHHHHHHHHH
VLVGTLGLLVYRQVKALKQSEDKYSLISTTANEGIWMLDADDRIIYVNPRVGEMFGYPGE
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCEEEEECCCHHHHCCCCCH
EMVGHPISSFMCPDQLADHEVRMRFRKEGGSERYERRFQHRDGRDVWTIISAAALIDDED
HHHCCCHHHCCCCHHHCCHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
GYQGVVAMCLDITDRKMSEERQTRLEEQLRQAHKMEAVGILAGGMAHDFNNLLQSIMGYI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
FLARMSVEADSEAREYLDEAEKISGQASELGQRLLLLSRGGVALLRAAPLAPLILPLVSS
HHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHEEEHCCCCEEEHHHCCHHHHHHHHHHC
ELEGTAITGEFDLPDDMPHVTMDEALMKQVISHLTVNAVETMPEGGTLRITGATLTITAK
CCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEC
NGLPLPAGRYVHIAFSDTGGGIPADNLPRIFDPYFTTKEMWNRKGMGLGLALCHTIIRKH
CCCCCCCCCEEEEEEECCCCCCCCCCCCCHHCCCCCHHHHHCCCCCCHHHHHHHHHHHHH
KGMISATSPVGEGATFNIYLPVAGEDAPTPFSAPPQFF
CCCEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SRFPSVMSKRILILVILVTVVFVGKVLFDITSDYGQVILSAERLSRGFATALNEHAVYT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
FSNAENTLDDLIQHLQERSSRAMPDERQLHRLLVNYRLKSPNSPFLFATTAGGRLHASSS
ECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEECCCCCCEEEEEECCCEEECCCC
DFPVRGLNLVNREYFQHHLNSRDTAPYISRSPNSLIDGDWLIFLTKRISNPDGSLRMIVG
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHCCCCCCEEEEEE
ISIDPLHLNDFYRSIELGTHDRIFLFRKDGAVLTLEPFYKAFMDKIIPPTDTIRRELAKR
EEECCEEHHHHHHHHCCCCCCEEEEEECCCCEEEEHHHHHHHHHHCCCCHHHHHHHHHHC
PHAGTIHMEQGLVDETSRIVSYRFSNRYPVVSVVSLREDDVLARWRARSAKSAAGALLLV
CCCCEEECCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHCCHHHHHHHHHH
VLVGTLGLLVYRQVKALKQSEDKYSLISTTANEGIWMLDADDRIIYVNPRVGEMFGYPGE
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCEEEEECCCHHHHCCCCCH
EMVGHPISSFMCPDQLADHEVRMRFRKEGGSERYERRFQHRDGRDVWTIISAAALIDDED
HHHCCCHHHCCCCHHHCCHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
GYQGVVAMCLDITDRKMSEERQTRLEEQLRQAHKMEAVGILAGGMAHDFNNLLQSIMGYI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
FLARMSVEADSEAREYLDEAEKISGQASELGQRLLLLSRGGVALLRAAPLAPLILPLVSS
HHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHEEEHCCCCEEEHHHCCHHHHHHHHHHC
ELEGTAITGEFDLPDDMPHVTMDEALMKQVISHLTVNAVETMPEGGTLRITGATLTITAK
CCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEC
NGLPLPAGRYVHIAFSDTGGGIPADNLPRIFDPYFTTKEMWNRKGMGLGLALCHTIIRKH
CCCCCCCCCEEEEEEECCCCCCCCCCCCCHHCCCCCHHHHHCCCCCCHHHHHHHHHHHHH
KGMISATSPVGEGATFNIYLPVAGEDAPTPFSAPPQFF
CCCEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3595559 [H]