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The map label for this gene is serC [H]

Identifier: 118579174

GI number: 118579174

Start: 773764

End: 774858

Strand: Reverse

Name: serC [H]

Synonym: Ppro_0735

Alternate gene names: 118579174

Gene position: 774858-773764 (Counterclockwise)

Preceding gene: 118579175

Following gene: 118579173

Centisome position: 19.33

GC content: 61.37

Gene sequence:

>1095_bases
ATGAAGCGTTTTTACAATTTTTCCGCAGGCCCCTCCATGCTCCCCGAATCCGTGCTCGCCAAGGCAGCCGACGAAATGCT
CTGCTACGAGACGAGCGGCCAGTCGGTCATGGAGATGTCCCATCGCTCCAAGCCGTTCGAAGCCATCATCGCCGGCGCCG
AGGCCCTGGTTCGCCAGAACATGGCTATCCCGGACGACTACCACGTGCTCTTCCTGCAGGGAGGCGCCAGCCTGCAGTTC
CACATGCTGCCGCTCAATTTCATGACCATCAACAAGAAGGCCGACTTCACCCTCACCGGCACCTGGGCACAGAAGGCCGC
GGAAGAGGCCAAGAGGCTGGGTACGGCCAACATCGTCGGCTCCTCCAAGGACAAGAAGTGGTCCTACCTGCCGGAAATCA
CGGGCGCAGACCCGGAAGCCGACTACTTCCACATCTGCTACAACAACACCATCGAGGGCACCCAGTATCACAGCATCCCC
GAGGTGGGCGCCGTGCCGCTGATCGGCGACATCTCTTCCGGCGTGCTCTCCGCGCCGCTGGACGTGACCCGTTTCGCCGT
GCTGTACGCCGGGGCACAGAAGAACCTGGGCCCGGCCGGCGTAACCCTGGTGATCATCCGCAAGGACATGATGGAGCGCA
TCCCGGCCGGACTTCCGGCCATGCTGAGCTACAAGACCCATGTGGACGGCGGTTCCATGTACAACACCCCTCCCTGCTAT
GCCATCTATATCTTCAAGCTGGTTCAGGAGTGGATCAGGGACATGGGTGGTGCGGAGGTCATCTACCGCCAGAACCAGGA
GAAGGCCAGACTGCTGTACGACTTCCTGGACAGTTCCTCACTCTTCTTCAGCCCGGTGGAGAAGAGCGTGCGCTCGCTGA
TGAACGTTCCCTTCCTGACCACCGAGAAGGACGCGGACAAGGCTGAGGCGCTCAACAAGAAGTTCGTCAAAGAGAGCGAG
GCGGCCGGCCTGGTCAACCTTGCCGGACACCGCTCCGTGGGGGGCATGCGCGCGTCGATCTACAACGCCATGCCACTGGA
AGGGGTGCAGGCCCTGGTGGCATTCATGAAAGAGTTCGAGGCGCGCTGCGCATAA

Upstream 100 bases:

>100_bases
GTGACAGCATCACCAGCCGCACAGCGGCAGTCGTGCCCACGGGAAGGCGCCCCGGTTTCCACCGGAGCGCCCTTCATCTC
ACACAGTAGAGGAAATGACA

Downstream 100 bases:

>100_bases
AACCGGAAAGAGCGTCTGGCCACAGAGCACACGAGAGTTCTCAGCGGAGAGCCAATCCTGGCCGGCATACCTCCGGGCAT
ACCGGCTAGCCTCCACTGAT

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MKRFYNFSAGPSMLPESVLAKAADEMLCYETSGQSVMEMSHRSKPFEAIIAGAEALVRQNMAIPDDYHVLFLQGGASLQF
HMLPLNFMTINKKADFTLTGTWAQKAAEEAKRLGTANIVGSSKDKKWSYLPEITGADPEADYFHICYNNTIEGTQYHSIP
EVGAVPLIGDISSGVLSAPLDVTRFAVLYAGAQKNLGPAGVTLVIIRKDMMERIPAGLPAMLSYKTHVDGGSMYNTPPCY
AIYIFKLVQEWIRDMGGAEVIYRQNQEKARLLYDFLDSSSLFFSPVEKSVRSLMNVPFLTTEKDADKAEALNKKFVKESE
AAGLVNLAGHRSVGGMRASIYNAMPLEGVQALVAFMKEFEARCA

Sequences:

>Translated_364_residues
MKRFYNFSAGPSMLPESVLAKAADEMLCYETSGQSVMEMSHRSKPFEAIIAGAEALVRQNMAIPDDYHVLFLQGGASLQF
HMLPLNFMTINKKADFTLTGTWAQKAAEEAKRLGTANIVGSSKDKKWSYLPEITGADPEADYFHICYNNTIEGTQYHSIP
EVGAVPLIGDISSGVLSAPLDVTRFAVLYAGAQKNLGPAGVTLVIIRKDMMERIPAGLPAMLSYKTHVDGGSMYNTPPCY
AIYIFKLVQEWIRDMGGAEVIYRQNQEKARLLYDFLDSSSLFFSPVEKSVRSLMNVPFLTTEKDADKAEALNKKFVKESE
AAGLVNLAGHRSVGGMRASIYNAMPLEGVQALVAFMKEFEARCA
>Mature_364_residues
MKRFYNFSAGPSMLPESVLAKAADEMLCYETSGQSVMEMSHRSKPFEAIIAGAEALVRQNMAIPDDYHVLFLQGGASLQF
HMLPLNFMTINKKADFTLTGTWAQKAAEEAKRLGTANIVGSSKDKKWSYLPEITGADPEADYFHICYNNTIEGTQYHSIP
EVGAVPLIGDISSGVLSAPLDVTRFAVLYAGAQKNLGPAGVTLVIIRKDMMERIPAGLPAMLSYKTHVDGGSMYNTPPCY
AIYIFKLVQEWIRDMGGAEVIYRQNQEKARLLYDFLDSSSLFFSPVEKSVRSLMNVPFLTTEKDADKAEALNKKFVKESE
AAGLVNLAGHRSVGGMRASIYNAMPLEGVQALVAFMKEFEARCA

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=363, Percent_Identity=44.3526170798898, Blast_Score=320, Evalue=1e-87,
Organism=Homo sapiens, GI10863955, Length=320, Percent_Identity=42.1875, Blast_Score=263, Evalue=2e-70,
Organism=Escherichia coli, GI1787136, Length=367, Percent_Identity=45.2316076294278, Blast_Score=301, Evalue=3e-83,
Organism=Caenorhabditis elegans, GI17506897, Length=368, Percent_Identity=40.4891304347826, Blast_Score=284, Evalue=4e-77,
Organism=Saccharomyces cerevisiae, GI6324758, Length=392, Percent_Identity=35.7142857142857, Blast_Score=232, Evalue=6e-62,
Organism=Drosophila melanogaster, GI21356589, Length=358, Percent_Identity=41.6201117318436, Blast_Score=289, Evalue=2e-78,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 40061; Mature: 40061

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRFYNFSAGPSMLPESVLAKAADEMLCYETSGQSVMEMSHRSKPFEAIIAGAEALVRQN
CCCEECCCCCCCCCHHHHHHHHHHHHEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHCC
MAIPDDYHVLFLQGGASLQFHMLPLNFMTINKKADFTLTGTWAQKAAEEAKRLGTANIVG
CCCCCCCEEEEEECCCCEEEEEEEEEEEEECCCCCEEEECHHHHHHHHHHHHCCCCEECC
SSKDKKWSYLPEITGADPEADYFHICYNNTIEGTQYHSIPEVGAVPLIGDISSGVLSAPL
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEECCCCCCHHCCCH
DVTRFAVLYAGAQKNLGPAGVTLVIIRKDMMERIPAGLPAMLSYKTHVDGGSMYNTPPCY
HHHHHHHHEECCCCCCCCCCEEEEEEEHHHHHHCCCCCCHHHEEEEECCCCCCCCCCCHH
AIYIFKLVQEWIRDMGGAEVIYRQNQEKARLLYDFLDSSSLFFSPVEKSVRSLMNVPFLT
HHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCEE
TEKDADKAEALNKKFVKESEAAGLVNLAGHRSVGGMRASIYNAMPLEGVQALVAFMKEFE
CCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHH
ARCA
HCCC
>Mature Secondary Structure
MKRFYNFSAGPSMLPESVLAKAADEMLCYETSGQSVMEMSHRSKPFEAIIAGAEALVRQN
CCCEECCCCCCCCCHHHHHHHHHHHHEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHCC
MAIPDDYHVLFLQGGASLQFHMLPLNFMTINKKADFTLTGTWAQKAAEEAKRLGTANIVG
CCCCCCCEEEEEECCCCEEEEEEEEEEEEECCCCCEEEECHHHHHHHHHHHHCCCCEECC
SSKDKKWSYLPEITGADPEADYFHICYNNTIEGTQYHSIPEVGAVPLIGDISSGVLSAPL
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEECCCCCCHHCCCH
DVTRFAVLYAGAQKNLGPAGVTLVIIRKDMMERIPAGLPAMLSYKTHVDGGSMYNTPPCY
HHHHHHHHEECCCCCCCCCCEEEEEEEHHHHHHCCCCCCHHHEEEEECCCCCCCCCCCHH
AIYIFKLVQEWIRDMGGAEVIYRQNQEKARLLYDFLDSSSLFFSPVEKSVRSLMNVPFLT
HHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCEE
TEKDADKAEALNKKFVKESEAAGLVNLAGHRSVGGMRASIYNAMPLEGVQALVAFMKEFE
CCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHH
ARCA
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA